• Journal of Korean Society of Forest Science
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• v.103 no.3
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• pp.439-445
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• 2014

In this study, we developed a dynamic stand yield model to estimate the baseline carbon stock, which is essentially required for a forest carbon offset project based on forest management. For developing the yield model, the data was acquired from the databases of the $5^{th}$ National Forest Inventory. The model was validated by comparing its estimations with field measurements that were conducted from 4 study sites (14 plots with thinning treatments) located in Hong-chun, Hoeng-sung, Yang-yang Daechi and Yang-yang Jungja. The difference between the estimations and the field measurements was less than 5%. Using the dynamic stand yield model, we estimated the changes in stand yield volume and carbon stocks for each species according to the baseline scenarios. As the results, we found that baseline carbon stock was the highest at Quercus acutissima stand (83.01tC/ha), while the lowest at Pinus rigida stand (32.17tC/ha) and Pinus densiflora stand of central region (39.09tC/ha). Hence, a project provider could get more carbon emission credits from an improved forest management project when considering the project with Pinus rigida stand or Pinus densiflora stand (central region). The baseline carbon stock and the dynamic stand yield model developed from this study would be useful for designing carbon offset projects based on improved forest management.

• Journal of Life Science
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• v.28 no.6
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• pp.681-687
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• 2018

Recently, several researchers have been developing cosmetics from natural ingredients for skin whitening and anti-aging products. The red sea cucumber (RSC), Apostichopus japonicas, is a species of sea cucumber in the family stichopodiae, which is widely distributed in China, Japan, and Korea. To use Red Sea Cucumber as a cosmetic ingredient, its inhibitory effects on melanogenesis and the anti-aging effects of RSC extracts were investigated. First, a tyrosinase activity assay was performed, which showed that RSC inhibited tyrosinase activity at a concentration of $200{\mu}g/ml$. An MTT assay was carried out to evaluate cell toxicity, and the results showed that RSC extract has no cytotoxicity in HaCaT cells. Furthermore, the mRNA expression levels of tyrosinase, tyrosinase related protein 1 (TRP-1), tyrosinase related protein 2 (TRP-2), microphthalmia-associated transcription factor (MITF), and matrix metalloproteinase (MMPs) genes treated with RSC extract in B16F10 and HaCaT cells decreased. Moreover, a wound-healing assay was performed to identify the cell regeneration effect of RSC extracts. Also, a skin turnover effect was confirmed by creating a three-dimensional cell culture with HaCaT and human fibroblasts. Altogether, the results suggested that Red Sea Cucumber may possess a high ability to induce whitening and anti-wrinkle effects as a cosmeceutical ingredient.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1666-1685
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• 2004

This present study was designed to screen medicinal plants for the treatment of brain diseases such as Parkinson's disease or aging. We tested the effects of the water extracts from 38 species medicinal plants on antioxidant capacity, monoamine oxidase B (MAO-B) inhibitory activity, acetylcholinesterase (AChE) inhibition and antiperoxidation activity in vitro. The water extracts from 38 species were tested on their antioxidant activity using radical scavenging effects against ABTS+. The water extract of C. sappan was showed the highest antioxidant capacity, the antioxidant activity at 1 Jig of herbal extract being 0.38mM TE. Lipid peroxidation in brain homogenates induced by NADPH and ADP-Fe/sup 2+/ was strong inhibited by C. sappan and R. palmatum extracts. Among the 38 medicinal plants investigated, R. palmatum showed significant biological activity (antioxidant capacity, MAO-B inhibiory activity, and AChE inhibitory activity). The protective efficacy of R. palmatum water extract on 1-methyl-4­phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism and its possible mechanism were studied in C57BL/6 mice. Treatment of R. palmatum water extract protected biomacromolecules such as lipids from oxidative damage induced by MPTP. The content of MDA in brain tissue was decreased significantly by R. palmatum extract. These results suggest that R. palmatum water extract plays on effective role in attenuating MPTP-induced neurotoxicity in mice. This protective effect of R. palmatum might be estimated the result from the inhibitory activity on monoamine oxidase B and the enhancement of antioxidant activity.

• Korean Security Journal
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• no.30
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• pp.117-138
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• 2012

To cope with rapidly increasing crimes, the Smart-home system has become common to minimize and prevent crimes in the residential space. Accordingly, the interest on the security-related Smart-home system is also increasing. First is the establishment of Smart-home security standard. At present, the Smart-home security systems are implemented by individual policies of construction companies or by the requirement of residents. Each construction company has their own characteristics in the Smart-home security system; while there is no standardized system. Second is the introduction of Smart-home security certificate system. Like people have certificates, now the residential spaces may also need certificates. A certificate system that represents the performance of residential spaces cannot be an absolute criterion in the evaluation of apartment quality, however, it can be a basic requirement for the convenient residential environment and policies being implemented by the government. If a certificate system would be introduced, construction companies will compete with each other to provide with better security system and apartment operation companies will hire more specialized security personnel in order to get higher certificates. Consequently, better security of residential space will be secured. It is also required to develop and establish response measures by studying the key changes and trends of Smart-home security system. The advance in mechanical security devices will bring about more changes in the future. Therefore, more various in-depth studies are required on the basic specifications of security system in the residential spaces.

• Korean Journal of Microbiology
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• v.43 no.1
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• pp.40-46
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• 2007

For restoration of disturbed ecosystem in Lake Paro, artificial floating island (AFI) was installed. Even though the lake water was oligo-mesotrophic, the macrophytes, such as Iris ensata, Iris pseudoacorus, Phragmites communis were growing well in the rubberized coconut fiber media. For elucidating this process, total bacterial numbers, active bacterial numbers and exoenzymatic activities of ${\beta}-glucosidase$ and phosphatase of pore water of media and lake water were analyzed. The average of total bacterial numbers, active bacterial numbers and exoenzymatic activities of ${\beta}-glucosidase$ and phosphatase were $28.6{\times}10^{6}\;cells/ml,\;22.7{\times}10^{6}\;cells/ml,\;452.9nM/L/hr,\;and\;16381.9nM/L/hr$ which were 10, 15, 22 and 38 times higher than those of lake water, respectively. Moreover, the total phosphorus and total nitrogen concentration of media showed high values of 0.82 mg/L and 7.0 mg/L, respectively, while those of lake water 0.07 mg/L and 2.3 mg/L. This results suggest that the bacteria was playing an important role for restoration of disturbed ecosystem with newly created microbial ecosystem in media of artificial floating island.

• Journal of Ginseng Research
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• v.35 no.3
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• pp.325-330
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• 2011

Red ginseng saponin fraction-A (RGSF-A) contains a high percentage of panaxadiol saponins that were isolated from Korean red ginseng by ultrafiltration. The aim of this study was to elucidate the effects of RGSF-A on the porcine distal left anterior descending (LAD) coronary artery. The relaxant responses to RGSF-A were examined during contractions induced by 100 nM U46619 (9,11-dideoxy-9a,11a-methanoepoxy-prostaglandin F2a), a stable analogue of thromboxane A2. RGSF-A dose-dependently induced biphasic (fast- and slow-) relaxation in the distal LAD coronary artery in the presence of an intact endothelium. The fast-relaxation was quickly achieved in a minute, and then the slow-relaxation was slowly developed and sustained for more than thirty minutes after the administration of RGSF-A. The slow-relaxation had a tendency to be bigger than the fast-relaxation. Fast relaxation induced by RGSF-A was almost blocked by $N_{\omega}$-Nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase synthase inhibitor and 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ), a guanylate cyclase inhibitor. However slow relaxation induced by RGSF-A was only partially inhibited by L-NAME and ODQ. In the endothelium-removed ring, RGSF-A evoked only slowrelaxation to a certain extent. These data suggest that RGSF-A induced both endothelium dependent fast- and slow-relaxation and endothelium independent slow-relaxation in the porcine distal LAD coronary artery. The endothelium dependent fast-relaxation is mediated by the nitric oxide (NO)-cGMP pathway, and the endothelium dependent slow-relaxation is at least partially mediated by the NO-cGMP pathway. However, the endothelium-independent slow-relaxation remains to be elucidated.

• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.151-163
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• 2011

Objectives : Our aim is to evaluate feasibility for massive clinical research and to make basic analysis of efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue. Methods : This study is a protocol for a pilot randomized controlled trial. It was developed through literature searches and discussions among researchers. Results : Forty participants allocated to acupuncture group and wait-list group. Participants allocated to acupuncture group will be treated three times per week for a total of 12 sessions over four weeks. Eight points (GV20; bilatral GB20, BL11, BL13, BL15, BL18, BL20, BL23) have been selected for the acupuncture group. Participants in the wait-list group will not receive acupuncture treatment during study period and follow-up will be made in the 5th and 9th weeks after random allocation. Then the same acupuncture treatment as that performed to the acupuncture group will be made to the wait-list group. Fatigue Severity Scale, a short form of Stress Response Inventory, Beck Depression Inventory, and Insomnia Severity Index will be used as outcome variables to evaluate the efficacy of acupuncture. Safety will be assessed at every visit. Conclusions : The trial based on this study will be performed. The results of the trial will provide basis for the efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue.

• Korean Journal of Environmental Agriculture
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• v.28 no.4
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• pp.412-418
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• 2009

This study is conducted in order to know the residue patterns of insecticide cypermethrin and fungicide diethofencarb in ginseng sprayed by various application methods. Two pesticides were sprayed separately on ginseng using traditional, soil and vinyl mulching applications. The vinyl mulching application was that head part of ginseng protected from pesticides. When cypermethrin was sprayed on ginseng by traditional application, its residue amount in ginseng was 0.25 mg/kg which exceeded 0.1 mg/kg, maximum residue limit(MRL) established by Korea Food & Drug Administration(KFDA). But in case of vinyl mulching and soil application, its residue amounts were 0.04 and 0.07 mg/kg, respectively. The residue amount of diethofencarb in ginseng was 3.01 mg/kg which exceeded the MRL, 0.3 mg/kg. Further, in case of vinyl mulching and soil application, its residue amounts were 1.71 and 9.39 mg/kg which exceeded the MRL 0.3 mg/kg. Although the residue amounts of both pesticides exceeded the MRLs for ginseng, we can explain that pesticides remained in head part of ginseng is probably the reason why higher pesticides residue levels were observed.

• BMB Reports
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• v.38 no.6
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• pp.755-762
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• 2005

Epstein-Barr virus (EBV) infects more than 90% of the world's population and has a potential oncogenic nature. A histone deacetylase (HDAC) inhibitor, trichostatin A (TSA), has shown potential ability in cancer chemoprevention and treatment, but its effect on EBV-infected Akata cells has not been examined. This study investigated the effect of TSA on the proliferation and apoptosis of the cells. TSA inhibited cell growth and induced cytotoxicity in the EBV infected Akata cells. TSA treatment sensitively induced apoptosis in the cell, which was demonstrated by the increased number of positively stained cells in the TUNEL assay, the migration of many cells to the sub-$G_0/G_1$ phase in flow cytometric analysis, and the ladder formation of genomic DNA. Western blot analysis showed that caspase-dependent pathways are involved in the TSA-induced apoptosis of EBV-infected Akata cells. Overall, this study shows that EBV-infected B lymphomas are quite sensitive to TSA-provoked apoptosis.

• 한국신재생에너지학회:학술대회논문집
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• 2011.05a
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• pp.196.2-196.2
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• 2011

지구온난화와 화석연료 고갈에 대한 우려로 전세계적으로 신재생에너지의 개발 및 활용이 본격화되고 있다. 특히, 다양한 신재생에너지원 중에서 날씨 및 계절에 의한 영향, 기저부하 담당, 지상 점유 면적, 소음 등 생활환경 영향, 경제성 등을 고려할 때 지열에너지는 미래 청정에너지원로서 기대와 관심이 집중되고 있다. 화산이 존재하지 않는 우리나라에서의 지열발전은 거의 불가능한 것으로 인식되어 지금까지의 심부 지열에너지 개발 프로젝트는 대부분 지역난방, 시설영농 등 직접이용을 목표로 추진되어 왔다. 그러나, 2003년부터 한국지질자원연구원에서 수행한 포항 심부지열에너지 개발사업의 결과로 얻어진 다양한 지질학적/지열학적 증거들을 토대로 분석한 결과, 국내 일부 지역에서는 지하 5 km 심도에서 최대 약 $180^{\circ}C$의 지온이 예상되어 국내에서도 심부 지열에너지를 이용한 지열발전에 대한 가능성이 제기되어 왔다. 여기에, 유럽과 미국 그리고 호주 등 선진국을 중심으로 비화산 지역에서 지하 심부에 인공적으로 지열저류층(파쇄대)을 생성하고 이를 통해 열매체(물)를 순환시킴으로써 생산된 증기를 발전에 활용하는 EGS (Enhanced Geothermal System) 기술이 개발되고 몇몇 성공사례가 발표되었다. 또한, 이러한 기술개발에 힘입어 EGS 지열발전에 대한 선진국의 과감한 연구비 투자가 이어졌다. 이러한 기술적 배경에 발맞추어 우리나라에서도 2010년 12월에 EGS 지열발전 과제가 착수되었다. 이 프로젝트는 아시아에서는 최초로 수행되는 EGS 기술 개발과제로서 2015년까지 약 480억원의 R&D 예산을 투입하여 MW급의 지열발전 pilot plant의 구축을 목표로 하고 있다. 프로젝트가 성공적으로 추진될 경우 국내외적인 파급효과는 매우 클것이다. 특히 2015년까지 1.5 MW의 pilot plant의 구축이 성공적으로 추진될 경우 국내에서는 2017년까지 3 MW 이상, 2020년까지 20 MW이상, 2030년까지 200 MW 이상의 지열발전이 가능할 것으로 기대된다. 또한 축적된 기술개발 경험을 바탕으로 인도네시아, 필리핀 등의 해외의 지열발전 사업에도 진출할 수 있는 계기가 될 것이다. 프로젝트는 넥스지오를 주관기관으로 하고 한국지질자원연구원, 한국건설기술연구원 및 서울대학교 등의 지질자원 관련 연구 및 교육기관과 포스코, 이노지오테크놀로지 등의 산업체가 참여하여 컨소시엄 형태로 추진하고 있으며, 향후 관심있는 여러 기관 및 산업체의 지원과 참여를 기대한다.