• Integrative Medicine Research
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• 제6권3호
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• pp.254-259
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• 2017

Background: Those classified as Tae-Eum (TE)-type people in Sasang constitutional medicine (SCM) are prone to obesity. Although extensive clinical observations have confirmed this tendency, the underlying physiological mechanisms are unknown. Here, we propose a novel hypothesis using integrative physiology to explain this phenomenon. Methods: Hypoactive lung function in the TE type indicates that respiration is attenuated at the cellular level - specifically, mitochondrial oxygen consumption. Because a functional reduction in cellular energy metabolism is suggestive of intrinsic hypoactivity in the consumption (or production) of metabolic energy, we reasoned that this tendency can readily cause weight gain via an increase in anabolism. Thus, this relationship can be derived from the graph of cellular metabolic power plotted against body weight. We analyzed the clinical data of 548 individuals to test this hypothesis. Results: The statistical analysis revealed that the cellular metabolic rate was lower in TEtype individuals and that their percentage of obesity (body mass index >25) was significantly higher compared to other constitutional groups. Conclusion: Lower cellular metabolic power can be an explanation for the obesity trend in TE type people.

• 사상체질의학회지
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• 제36권1호
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• pp.13-30
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• 2024

Objectives This study aimed to analyze the influence of various sleep-related factors that affect sleep quality by each Sasang type. Methods A total of 400 subjects were included for this study, 108 males and 292 females. Sasang type was diagnosed using the SCAT. Then, the characteristics of each Sasang type were analyzed using HRV, DITI, and PSQI, PSS, and SDFI questionnaires. Logistic regression analysis was used to predict sleep-related factors that affect sleep disorders by Sasang types. Results This study shows that the pathophysiological characteristics for stress and digestive function of each Sasang type can differentiate sleep management through a logistic regression model including subscales of PSS and SDFI. Stress had no effect on the occurrence of sleep disturbance within only So-Eum, since the stress level is originally high in the So-Eum regardless of sleep quality. Rather, decreased appetite and poor eating habits had a significant impact on the decline in sleep quality. In addition, poor digestion and eating habits in So-Yang had a greater impact and poor digestion in Tae-Eum had a greater impact on the decline in sleep quality. Conclusion The stress and subscales of digestive function provide differentiated sleep management in So-Yang, Tae-Eum, and So-Eum types. The individualized sleep management for each Sasang type with statistically validated PSS and SDFI would be useful for sleep-related experts planning safe and effective person-centered health care as well as for Western clinicians who want to incorporate Sasang typology into their treatments as integrative medical technique in the future.

• 동의신경정신과학회지
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• 제26권4호
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• pp.337-348
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• 2015

Objectives: The purpose of this study was to review previous clinical studies on underlying mechanisms of sleep-related type-specific pathophysiological symptoms among the Sasang types. Methods and Procedure: We reviewed seven research databases from December 2003 to August 2015 with the keywords Sasang typology, constitution and sleep. The Sasang type-specific sleep-related symptoms were analyzed based on seven categories, including subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medications and daytime dysfunction. Results: Total of twelve studies were included in the analysis. The Tae-Yang type showed low subjective sleep quality, long sleep latency and frequent awakening, and the So-Yang type showed long sleep latency. The Tae-Eum type presented high subjective sleep quality, short sleep duration, frequent snore, toss and turn during the sleep, and insomnia and low frequency of dream. The So-Eum type showed long sleep latency in male and high frequency of dream. The Eum type combining Tae-Eum and So-Eum types had higher subjective sleep quality, longer sleep duration and higher frequency of dream than the Yang type combining Tae-Yang and So-Yang types.Conclusions This study reviewed type-specific sleep-related characteristics and discussed possible pathophysiological mechanisms involved. Differences in sleep characteristics among the Sasang types might stem from type-specific temperaments and require further study.

• 한국의사학회지
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• 제26권2호
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• pp.23-29
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• 2013

Objectives : The purpose of this study is to extend indications of Four-Constitution Medicinal formulas by comparing with formulas on Dongeuibogam(東醫寶鑑), focusing on their composition. Methods : 1. We analyzed the composition of Four-Constitution Medicine formula which are mentioned on Donguisusebowon(東醫壽世保元), focusing on their composition. 2. We analyzed the composition of formulas on Dongeuibogam(東醫寶鑑) comparing with 24 formulas for So-Eum type, 17 formulas for So-Yang type, 24 formulas for Tae-Eum type, 2 formulas for Tae-Yang type. Results & Conclusions : 1. We finally selected 14 formulas and its effect as similar formulas with Bojungyikgi-tang, Insamjinpi-tang, Cheongunggyeji-tang, Palmulgunja-tang, Hwanggigyejibuja-tang, Hwanggigyeji-tang for So-Eum type. 2. We finally selected 4 formulas and its effect as similar formulas with Dokwaljihwang-tang, Sukjihwanggosam-tang for So-Yang type.

• 동의생리병리학회지
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• 제24권4호
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• pp.722-726
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• 2010

This study was to examine the neuroticism related to psychological characteristics of each Sasang types using SCL-90-R with 107 students from College of Oriental Medicine, Daeguhaani University. We did ANOVA analysis with seven neuroticism-related sub-scales and found significant differences in somatization (F=3.701, p=0.028) and hostility (F=4.396, p=0.015). The post-hoc analysis showed that the So-Yang type ($23.17{\pm}8.95$) has significantly (p=0.048, p=0.012) higher score than Tae-Eum ($19.25{\pm}5.97$) and So-Yang($19.25{\pm}5.76$) type in somatization. In hostility, the So-yang type ($11.31{\pm}3.98$) has significantly (p=0.011, p=0.015) higher score than Tae-Eum ($8.80{\pm}2.61$) and So-Eum ($9.44{\pm}3.35$) type. The ANOVA analysis with female subjects found significant differences in anxiety (F=3.88, p=0.03) and hostility (F=5.04, p=0.01). The post-hoc analysis showed that the So-Yang type ($20.36{\pm}5.44$, $12.36{\pm}3.82$) has significantly (p=0.043, p=0.015) higher score compared to the So-Eum type ($15.46{\pm}3.36$, $8.69{\pm}2.06$) in anxiety and hostility. The profile analysis using seven neuroticism-related subscalesof SCL-90-R did not revealed significant differences (Flatness with Greenhouse-Geisser (F=202.347, p=0.0001), Parallelism with Greenhouse-Geisser (F=1.428, p=0.191)). We discussed the implications of neuroticism in Sasang typology and SCL-90-R somatization, anxiety and hostility scales. This study showed opposite results compared to the previous studies that So-Eum type has higher neuroticism compared to the So-Yang and Tae-Eum type. The reason for this discrepancy between this and previous studies, and differences between male and female should be examined thoroughly with larger and balanced sample.

• 사상체질의학회지
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• 제34권4호
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• pp.13-26
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• 2022

Objectives The purpose of this study was to explore the differences in allergic reactions by type of Sasang constitution using multiple allergen simultaneous test(MAST). Methods This study was conducted using the big data of Korean medical health checkups. Subjects with a history of allergic disease, Sasang constitution type information, and MAST results were included. Subjects who had taken drugs before MAST that affected allergic reactions were excluded. We compared total immunoglobulin E(IgE) concentrations, and the number of positive antigens by Sasang constitution using analysis of variance. The presence or absence of a positive reaction and specific IgE concentration classes of 92 antigens in MAST were analyzed by Fisher's exact test or Chi-squared test. Results The distribution of Sasang constitutional types of Tae-Yang, Tae-Eum, So-Yang, and So-Eum among 147 subjects was 2.7%, 42.9%, 38.1%, and 16.3%, respectively. There was no statistically significant difference in the total IgE concentration, the number of positive antigens, and specific IgE concentration classes for each antigen. There was a statistically significant difference in MAST-positive reaction for alder and pine antigens by type of Sasang constitution, and Tae-Eum had the most. Conclusions Tae-Eum showed a relatively strong positive reaction to a large number of antigens compared to the other types, but no statistically significant difference was observed. It is necessary to continuously investigate allergic reactions to provide evidence for the treatment of allergic diseases by Sasang constitution.

• 사상체질의학회지
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• 제21권1호
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• pp.217-226
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• 2009

1. Objective To investigate characteristics of menstrual patterns according to Sasang Constitutional disease, and to utilize for diagnosis and treatment of Sasang Constitutional disease. 2. Method The recruited subjects were 430 women who convinced their Sasang Constitution by taking herbal medicine and improving of chief complaint. The items of data contain age at menarche, age at menopause, menstrual cycle, menstrual duration, cyclic regularity of menstruation, severity of menstrual pain, the worst day of menstrual pain, type of menstrual pain, amount of menstruation. 3. Results 1) Severity of menstrual pain, the worst day of menstrual pain, menstrual pain accompanied with nausea were significant among Sasang Constitutional diseases. 2) In Bae-chu-pyo-byeong disease (背椎表病證), Wi-wan-han disease (胃院寒證), So-eum disease (少陰證) and Tae-eum disease (太陰證), menstrual pain was severer than other diseases. 3) In Hae-yeok disease and So-yang-sang-pung disease (少陽傷風證), the worst day of menstrual pain was a day before menstruation. In Hyung-gyeok-yeol disease (胸膈熱證), Tae-eum disease (太陰證), So-eum disease (少陰證), the frequency of a day after menstruation in the worst day of menstrual pain was higher than other diseases. In Wi-wan-han disease (胃院寒證), Mang-yang disease (亡陽證), the frequency of two day after menstruation in the worst day of menstrual pain was higher than other diseases. 4) In So-yang-sang-pung disease (少陽傷風證), Mang-eum disease (亡陰證), Eum-heo-o-yeol diasese (陰虛午熱證), Ul-gwang disease (鬱狂證), Tae-eum disease (太陰證), So-eum disease (少陰證), the frequency of menstrual pain accompanied with nausea were higher than other diseases. 4. Conclusion Menstrual patterns, especially menstrual pain is different among Sasang Constitutional diseases. Assessing menstrual pain can be used for diagnosing Sasang Constitutional diseases, deciding treatment course, determinating prognosis.

• International Journal of Advanced Culture Technology
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• 제7권2호
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• pp.77-82
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• 2019

This research aims to analyze the Sasang constitutions of army soldiers using the measuring tools which were developed by the Korea Institute of Oriental Medicine the government-affiliated Ministry of Science. Then, this research compares the The Sasang constitutions of soldiers to the Sasang typology of Yi Je-Ma, who systemized Korean traditional medicine in 1800s. Also, by comparing each result of subjected army unit, we will recommend proper diet management at regular intervals in order to enhance morals of soldiers. Finally, we also suggest to apply Sasang constitution to consultation in military so as to strengthen the combat power of the army.

• 동의생리병리학회지
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• 제19권6호
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• pp.1491-1495
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• 2005

The purpose of this study was to investigate the personality traits in three constitutional types, So-yang, So-eum and Tae-eum, using NEO-PI-R. The Questionnaire for QSCC II and NEO-PI-R Korean version were completed by 155 university students (108 males and 47 females), Analysis of difference among groups was conducted by ANOVA and followed by Scheffe test. Significant differences of personality among three constitutional types were revealed with respect to NEO-PI-R scales such as Extroversion and Openness in the big five factors and Anxiety, Angry ,Gregariousness, Assertiveness, Excitement Seeking, positive Emotion, Fantasy, Feeling, Action, Values, Modest and Deliberation in subtypesof the big five factors. The score of So-yang is significantly higher than that of so-eum in Extroversion, Openness, Angry, Gregariousness, Assertiveness, Excitement Seeking, Positive Emotion, Fantasy, Action and Values. The score of So-yang is significantly higher than that of Tae-eum in Extroversion, Openness, Gregariousness, Assertiveness, Excitement Seeking, Feeling, Action and Values. The score of So-eum is significantly higher than that of So-yang in Anxiety, Modest and Deliberation. The results Suggst that NEO-PI-R is helpful to determine constitution type, especially in the level of personality.

• 약학회지
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• 제58권1호
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• pp.71-79
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• 2014

Although Korean patients with type 2 diabetes mellitus (T2DM) are generally treated by western medicine, many of them strongly believe in the traditional oriental Sasang constitutional classification and depend on it for food, health supplements, and oriental medicines decision making. Sasang constitutional classification is a part of traditional Korean medicine that divides people into four constitutional types (Tae-Yang: TY, Tae-Eum: TE, So-Yang: SY, and So-Eum: SE), which differ in inherited characteristics such as appearance, personality traits, susceptibility to diseases, and drug responses. It is recommended for T2DM patients to control their blood glucose very well from early stages with drugs and diet. However, many T2DM patients respond differently to their drugs, even though they receive the same medicine. Therefore, the present study investigated whether Sasang constitutional type can explain the therapeutic differences between oral hypoglycemic agents (OHAs) therapy (mono, dual and triple drug therapy). Patients of 618 with T2DM diagnosis and Sasang constitutional type known who received both western and oriental medicine treatment in a hospital between April 2006 and April 2013 retrospectively studied. HbA1c (%) and blood glucose (mg/dl) levels before OHAs therapy and 3 month after were collected for metformin (MET) or sulfonylurea (SU) monotherapy, MET+SU dual therapy, MET+except SU (where was either alpha-glucosidase inhibitor, dipeptidyl peptidase-4 inhibitor, meglitinide or thiazolidinedione) dual therapy, and triple therapy, according to Sasang constitutional type. For statistical analysis, ANOVA was used and paired t-test by SPSS 19.0 where P values less than 0.05 were considered statistically significant. Pattern was similar levels of HbA1c and blood glucose and which was decreased in order of mono, MET+SU dual, MET+except SU dual and triple therapy. In all patients comparison, for the So-yang (SY) constitutional type, either monotherapy was less effective; for Te-eum (TE) type, MET+SU dual therapy was less effective while MET+except SU dual therapy was more effective and the triple therapy was less effective; and for So-eum (SE) type, the triple therapy was more effective. For the management of TE type it is recommended to use drugs except SU when dual therapy is needed, restrict triple therapy and consider dual and insulin therapy; for SY type it is recommended to follow current guidelines; and for SE type it is advisable to skip dual therapy and start the triple therapy early. Finally, the therapeutic response to OHAs is different among Korean T2DM patients with different Sasang constitutional types. Taken together, the choice of effective OHAs therapy for each type is necessary in order to minimize the poor control of blood glucose level, the risk of complications, and the costs from a failure of therapy.