• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.4
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• pp.239-245
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• 2012

Purpose: Vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis and lymphangiogenesis including induction of endothelial cell proliferation, migration and capillary tube formation. E7080 (S1164, Selleck chemical, Houston, TX, USA) is a muti-targeted kinase inhibitor, which targets VEGF receptor-2, 3 (VEGFR-2, 3) and inhibits survival and proliferation of tumor cell. The purpose of this study was to determine the anti-tumor effect of E7080 on oral squamous cell carcinoma. Methods: An oral squamous cell carcinoma cell line, SCC-9 was used in this study. E7080 was applied to SCC-9 cells by 3 different concentrations (1, 5, 10 ${\mu}g/mL$). Control means no application of E7080. The cellular growth was evaluated by real-time cell electronic sensing and MTT assay. The signal transduction was evaluated by Western blotting. Results: In experimental group, SCC-9 cell proliferation was decreased and the VEGFR-3 downstream pathways were inhibited compared with control. Furthermore, increasing the concentration of E7080, the ability of E7080 to disturbance of SCC-9 cell proliferation was increased. Conclusion: Proliferation of SCC-9 cells was inhibited by E7080, which was through by inhibition of VEGFR-3 downstream pathway. In vivo study with E7080 will be required to provide therapeutic benefits in oral squamous cell carcinoma.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.8A
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• pp.1252-1258
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• 1999

This paper describes a COMS IF transceiver IC for 10-MHz bandwidth wireless local loops. It interfaces between the RF section and the digital MODEM section and performs the IF-to-baseband (Rx) and baseband-to-IF (Tx) frequency conversions. The chip incorporates variable gain amplifiers, phase-locked loops, low pass filters, analog-to-digital and digital-to-analog converters. It has been implemented in a 0.6 -${\mu}{\textrm}{m}$ 2-poly 3-metal CMOS process. The phase-locked loops include voltage-controlled oscillators, dividers, phase detectors, and charge pumps on chip. The only external complonents are the filter and the varactor-tuned LC tank circuit. The chip size is 4 mm $\times$ 4 mm and the total supply current is about 57 mA at 3.3 V.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 1997.10a
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• pp.1.1-32
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• 1997

Atmospheric monitoring capabilities were established in 1988 by the University of Florida at Duke forest, near Durham. NC: Cary forest, near Gainesville, FL: and Austin forest, near Nacogdoches, TX. Continuous (hourly averaged) measurements of air quality (ozone, nitrogen oxides and sulfur dioxide) and meteorological variables were made at these three low elevation (< 200 meters), rural locations in the southeastern U.S. for more than three years. During the same period at these sites wet and dry acid deposition samples were collected and analyzed on an event and weekly basis, respectively The monitoring locations were selected to determine actual atmospheric exposure indices for southern pine species in support of on-site surrogate exposure chamber studies conducted by Southern Commercial Forest Research Cooperative (SCFRC) investigators. Daily and quarterly averaged ozone maxima were higher (55 ppb) at the northernmost site in the network (Duke forest) in the second and third quarters (spring and summer seasons) and lower (35 ppb) in the first and fourth quarters (winter and fall seasons), when compared to ozone levels at the two southernmost sites (Cary and Austin forests). Seasonal ozone levels at the latter two sites were similar Nitrogen oxieds and sulfur dioxide levels were insignificant (< 5 ppb) most of the time at all sites, although soil emissions of NO at two sites were found to influence nighttime ozone concentrations. Typical maximum quarterly and annual aggregate ozone exposure indices were significantly higher at Duke forest (92.5/259 ppm-hr) than those values observed at the two southern sites (65.6/210 ppm-hr). Acid deposition (wet and dry) components concentrations and deposition fluxes observed at the Duke forest, NC piedmont site, were generally greater, dependent on site and season, than corresponding variables measured at either of the two southern coastal plain sites (Cary and Austin forests). Acid deposition variables observed at the latter two sites were remarkably similar, both qualitatively and quantitatively, although the sites were located 1300 km apart. A comparison of deposition fluxes of elemental nitrogen (NO3, NH4') and sulfur (5042-, SO3) components in wet and dry forms indicated that wet deposition accounts for approximately 70% of the total nitrogen and 73% of the total sulfur input on an annual equivalent basis at all sites.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.40 no.3
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• pp.1-9
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• 2003

In this paper, we designed a highly suppressed sidelobe ladder type RF SAW bandpass filter based on 1-port resonator, for 800 MHz mobile communication system. In order to get the highest device characteristics, we optimized some important parameters such as the electrode thickness, electrode lambda weghting of the reflectors, and static capacitance ratio. Furthermore, we fabricated the Tx and Rx. filter using optimized parameters. Implemented filters can be used in 800 MHz mobile communication system and external impedance matching circuits are not needed. RF filter was fabricated on 36$^{\circ}$LiTaO$_3$ substrates with Al-Cu (W 3 %)and mounted 3.8mm$\times$3.8mm$\times$1.5mm SMD package. Developed filters has 2.3 dB insertion loss in the 25 MHz pass-band, 33MHz with 3-dB insertion loss, stop-band rejection of 30 dB, passband ripple is less than 0.5 The power durability of the filters measured about 3.5W and the maximum temperature variation within -2$0^{\circ}C$~8$0^{\circ}C$ was 0.09 dB/$^{\circ}C$ of 3-dB insertion loss.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.10
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• pp.1109-1115
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• 2010

FMCW(Frequency Modulation Continuous Wave) Radar can detect the distance and the velocity of forward obstacles using linearly modulated FM signal. For better performance, the RF of radar should be operated with wideband frequency linearity on 300 MHz bandwidth at 77 GHz carrier frequency. In this paper, we propose a simple method for improving frequency linearity of FMCW radar implemented with VCO. The proposed method shows that the Voltage-Frequency relation of VCO could be measured by using the modified Tx waveform of FMCW radar. Then the measured nonlinearity could be compensated using LUT(Look-up Table) with easy. It is noted that the proposed can be adopted in existing system without extra circuit.

• Journal of Korea Foundry Society
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• v.34 no.3
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• pp.94-99
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• 2014

A commercially used Zr-based amorphous alloy was recycled and the effects of introducing carbon during recycling on the glass forming ability and mechanical properties of the alloy were investigated. The initial carbon content used in this study was 229ppm. The carbon content was gradually increased as the number of recycling iterations was increased and after the $4^{th}$ recycling it rapidly increased. As return scrap was recycled, polygonal particles precipitated, and they were identified as ZrC. The amount of the precipitates also increased with recycling. Tg, Tx and ${\Delta}T$ of the base alloy were 615 K, 696 K and 81 Kr respectively and they changed to 634 K, 706 K and 72 K after the $10^{th}$ recycling. The decrease of the ${\Delta}T$ value indicates deterioration of the glass forming ability. Hardness was not changed during three iterations of recycling but after the $4^{th}$ recycling it significantly increased. This is ascribed to an increase of amount of the hard particles, namely ZrC.

• Journal of Advanced Marine Engineering and Technology
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• v.36 no.4
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• pp.504-511
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• 2012

In this paper, level instrument is implemented using beat frequency for distance measurement which means the difference between Tx and Rx signal frequency from FMCW Radar Level Transmitter. Beat frequency is analyzed through Fast Fourier Transform of which frequency precision can be improved by applying Zoom FFT. Distance precision is improved from 146.5[mm] to 5[mm] using the advantage of Zoom FFT which can raise the frequency precision without changing the sampling frequency or FFT point number to be fixed in the beginning of designing signal processing. Also, measurement error can be reduced within 2[mm] by incresing the FFT points using the method of Spline interpolation. For verifying the effectiveness of this Zoom FFT to FMCW Radar Level Transmitter, test bench is made to measure the distance for every 1[mm] between 700[mm] and 2000[mm] and measurement error can be checked in the range of ${\pm}2$[mm].

• Journal of Korea Society of Industrial Information Systems
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• v.17 no.2
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• pp.19-27
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• 2012

In railway tunnel environment, the reliability of a high-data-rate and real-time train-to-wayside communication should be maintained especially when high-speed train moves along the track. In China and Europe, the communication frequency around 900 MHz is widely used for railway applications. At this carrier frequency band, both of the solutions based on continuously laid leaky coaxial cable (LCX) and discretely installed base-station antennas (BSAs), are applied in tunnel radio coverage. Many available works have concentrated on the radio-wave propagation in tunnels by different kinds of prediction models. Most of them solve this problem as natural propagation in a relatively large hollow waveguide, by neglecting the transmitting/receiving (Tx/Rx) components. However, within such confined areas like railway tunnels especially loaded with train, the complex communication environment becomes an important factor that would affect the quality of the signal transmission. This paper will apply a full-wave numerical method to this case, for considering the BSA or LCX, train antennas and their interacted environments, such as the locomotive body, overhead line for power supply, locomotive pantograph, steel rails, ballastless track, tunnel walls, etc.. Involving finite-difference time-domain (FDTD) method and uni-axial anisotropic perfectly matched layer (UPML) technique, the entire wireless RF downlinks of BSA and LCX to tunnel space to train antenna are precisely modeled (so-called integrative modeling technique, IMT). When exciting the BSA and LCX separately, the field distributions of some cross-sections in a rectangular tunnel are presented. It can be found that the influence of the locomotive body and other tunnel environments is very significant. The field coverage on the locomotive roof plane where the train antennas mounted, seems more homogenous when the side-laying position of the BSA or LCX is much higher. Also, much smoother field coverage solution is achieved by choosing LCX for its characteristic of more homogenous electromagnetic wave radiation.

• The Journal of the Petrological Society of Korea
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• v.19 no.4
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• pp.245-254
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• 2010

Technology of surface investigation using X-ray is one of widely used technology nowadays. This technique has been numerously used for planetary surface investigations for both orbital and rover scientific instruments. Korea has a plan to send an orbiter and lander to the Moon by the early 2020s. Therefore, the time has come for Korean researchers to develop major scientific instruments and start to do research on basic research for the Moon. Because of this situation, we firstly investigate X-ray technology, which is essential as one of core techniques of planetary remote sensing from the orbit and ground. This paper presents the current status of planetary exploration using X-ray techniques and new development of worldwide X-ray technology which could be adapted for prospective planetary missions.

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.580-592
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• 2009

Objectives : This study had been performed for Respondents who live in Daegu and Kyungbuk province Age group of 30 to 50 years old. Methods : The oral health state and oral heath care, dental treatments about the use of oral hygiene devices were obtained through self-administering questionnaires from 2 to 31, January, 2009. Results : 1. The toothpick was well known for respondents and automatic brush, gargle, dental floss were practically used. 2. 57.1% of man know oral hygiene device, they know more about oral hygiene device if they have higher degree, and they use more if they are older than others. 3. 55.5% of respondents who think their oral health condition is not healthy enough recognize oral hygiene device, 77.5% of respondents who visited dental clinic around six month recognize oral hygiene device. 82.4% of respondents who had been follow-up. 86.1% of respondents who think their oral health state is good enough doesn't use oral hygiene device, oral hygiene device was used more for respondents who visited dental clinic frequently. 47.1% of respondents who visited dental clinic periodically use oral hygiene device. 4. Respondents who experience implant recognize more about oral hygiene device and periodontal Tx, orthodontics problem, preservative treatment were next. 5. 60.0% of respondents who were educated tooth brushing method recognize it. Oral hygiene device was frequently used if tooth brushing time were increased. 26.4% of respondents who were changed their tooth brushing method used oral hygiene device. Conclusions : Their recognition level was practically low whose age is around 30 to 50. Their oral hygiene device use ratio is higher then others who were educated tooth brush method so that I think we need to recommend for use oral hygiene device and use method.