• Title/Summary/Keyword: TR-state

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The Change of Taurine Transport in Variable Stress States through the Inner Blood-Retinal Barrier using In Vitro Model

  • Kang, Young-Sook;Lee, Na-Young;Chung, Yeon-Yee
    • Biomolecules & Therapeutics
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    • v.17 no.2
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    • pp.175-180
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    • 2009
  • Taurine is the most abundant free amino acid in the retina and transported into retina via taurine transporter (TauT) at the inner blood-retinal barrier (iBRB). In the present study, we investigated whether the taurine transport at the iBRB is regulated by oxidative stress or disease-like state in a conditionally immortalized rat retinal capillary endothelial cell line (TR-iBRB) used as an in vitro model of iBRB. First, [$^3H$]taurine uptake and efflux by TR-iBRB were regulated in the presence of extracellular $Ca^{2+}$. [$^3H$]Taurine uptake was inhibited and efflux was enhanced under $Ca^{2+}$ free condition in the cells. In addition, oxidative stress inducing agents such as tumor necrosis factor-$\alpha$ (TNF-$\alpha$), lipopolysaccharide (LPS), diethyl maleate (DEM) and glutamate increased [$^3H$]taurine uptake and decreased [$^3H$]taurine efflux in TR-iBRB cells. Whereas, 3-morpholinosydnonimine (SIN-1), which is known to NO donor decreased [$^3H$]taurine uptake. Lastly, TR-iBRB cells exposed to high glucose (25 mM) medium and the [$^3H$]taurine uptake was reduced about 20% at the condition. Also, [$^3H$]taurine uptake was decreased by cytochalasin B, which is known to glucose transport inhibitor. In conclusion, taurine transport in TR-iBRB cells is regulated diversely at extracellular $Ca^{2+}$, oxidative stress and hyperglycemic condition. It suggested that taurine would play a role as a retinal protector in diverse disease states.

Flexural strength of high-strength concrete filled steel tube columns strengthened by carbon fiber sheets (탄소섬유쉬트로 보강한 고강도 콘크리트 충전강관(CFT) 기둥의 휨내력에 관한 연구)

  • Park, Jai-Woo;Hong, Young-Kyun;Hong, Gi-Soup
    • Journal of the Earthquake Engineering Society of Korea
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    • v.12 no.1
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    • pp.21-28
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    • 2008
  • The CFT (Concrete Filled Steel Tube) columns became popular in high rise building construction due to not only its composite effect but also economic advantage. However, it has been pointed out in various previous researches that the current practice in CFT columns may lead the steel tube to probable local buckling at critical sections of the columns right after yielding. To resolve such a problem, the TR-CFT (Transversely Reinforced Concrete Filled Steel Tube) column is proposed to control or at least delay the local buckling state at the critical section by wrapping the CFT columns with carbon fiber sheet. The validity of the proposed column system is validated through the present paper by observing the experimental performance and comparing it with the analytical prediction of the TR-CFT columns with hish strength concrete. It is also shown that the current design code provisions such as ACI-318, in which the contribution of concrete confining effect filled in steel tube is not appropriately accounted for, may contain too much conservatism.

Effect of Phenyl Vinyl Methyl Silicone (PVMQ) on Low Temperature Sealing Performance of Fluorosilicone Composites

  • Lee, Jin Hyok;Bae, Jong Woo;Choi, Myoung Chan;Yun, Yu-Mi;Jo, Nam-Ju
    • Elastomers and Composites
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    • v.56 no.4
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    • pp.209-216
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    • 2021
  • In this study, we observed the mechanical properties, thermal stability, and low temperature sealing performance of fluorosilicone elastic composites. When the blend ratio of Phenyl vinyl methyl silicone (PVMQ) was increased, the tensile strength, modulus at 100%, and compression set were decreased. The thermal stability of fluorosilicone elastic composites showed a similar tendency. These were caused by poorer green strength of PVMQ than Fluorosilicone rubber (FVMQ). The change in the tensile strength and elongation at -40℃ showed a decreasing tendency with increasing PVMQ blend ratio. By increasing the PVMQ blend ratio, low-temperature performance was improved. The Dynamic mechanical analysis (DMA) results showed that Tg was decreased and low-temperature performance was improved with increasing PVMQ blend ratio. However tanδ was decreased becaused of the poor green strength and elasticity of PVMQ. From a hysteresis loss at -40℃, the hysteresis loss value was increased and fluorosilicone elastic composites showed the decreasing tendency of elasticity with increasing PVMQ blend ratio. From the TR test, TR10 was decreased with increasing PVMQ blend ratio. FS-4 (45% PVMQ blended composites) showed a TR10 of -68.0℃ that was 5℃ lower than that of FS-1 (100% FVMQ). The gas leakage temperature was decreased with increasing PVMQ blend ratio. The gas leakage temperature of FS-4 was -69.2℃ that was 5℃ lower than that of FS-1. Caused by the polymer chain started to transfer from a glassy state to a rubbery state and had a mobility of chain under Tg, the gas leakage temperature showed a lower value than Tg. The sealing performance at low temperature was dominated by Tg that directly affected the mobility of the polymer chain.

A study on insulation Characteristics of XLPE by various additives (다양한 첨가제에 따른 가교폴리에틸렌의 절연특성 분석)

  • Song, Sang-Min;Kim, Gyu-Sik;Son, Won-Keun;Ryu, Boo-Hyung;Park, Soo-Gil
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.05c
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    • pp.193-196
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    • 2001
  • XLPE is occasionally happened to deteriorate cable insulation characteristics. It is happened to do a breakdown state by the degradation of electrical characteristic and electrical breakdown strength. I prepared TR-XLPE (Tree-Retardant XLPE) as adding various additives to prevent its states. Various additives are treeing retardants, anti-oxidants. Treeing retardants three kinds of aromatic compounds as adding each additive. Anti-oxidants use quinone compound and cresol compound as adding each additive. In order to observe each electrical characteristics, I measured breakdown strength, relative dielectric constant$({\varepsilon}_r)$, dielectric loss tangent$(tan{\delta})$. TR-XLPE specimens as adding treeing retardants and anti-oxidants enhance breakdown strength, ${\varepsilon}_r$, $tan{\delta}$ than pure XLPE.

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Factorization of the Jet Mass Distribution in the Small R Limit

  • Idilbi, Ahmad;Kim, Chul
    • Journal of the Korean Physical Society
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    • v.73 no.9
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    • pp.1230-1239
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    • 2018
  • We derive a factorization theorem for the jet mass distribution with a given $p^J_T$ for the inclusive production, where $p^J_T$ is a large jet transverse momentum. Considering the small jet radius limit ($R{\ll}1$), we factorize the scattering cross section into a partonic cross section, the fragmentation function to a jet, and the jet mass distribution function. The decoupled jet mass distributions for quark and gluon jets are well-normalized and scale invariant, and they can be extracted from the ratio of two scattering cross sections such as $d{\sigma}/(dp^J_TdM^2_J)$ and $d{\sigma}/dp^J_T $. When $M_J{\sim}p^J_TR$, the perturbative series expansion for the jet mass distributions works well. As the jet mass becomes small, large logarithms of $M_J/(p^J_TR)$ appear, and they can be systematically resummed through a more refined factorization theorem for the jet mass distribution.

Effect of Self-Complex Exercise Program on Pain, Function, Psychosocial, Balance Ability, and TrA Muscle in Patients with Lumbar Instability: A Randomized Controlled Trial (허리 불안정성이 있는 허리통증 환자에게 실시한 자가-복합 운동프로그램이 통증과 기능, 심리사회적, 균형 능력 그리고 배가로근에 미치는 효과)

  • Yoon, Jong-Hyuk;Jeong, Dae-Keun;Park, Sam-Ho
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.2
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    • pp.73-83
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    • 2022
  • Purpose : Low back pain (LBP) is reported as a risk of experiencing musculoskeletal disorders due to muscle stiffness and hypokinetics. The lumbar spine in an unstable state causes imbalance and lumbar instability. Therefore, This study examined the effects of lumbar stabilization exercise and self-complex exercise program on pain, function, psychosocial level, static balance ability, and transverse abdominal muscle (TrA) thickness and contraction ratio in patients with lumbar instability. Methods : The design of this is a randomized controlled trial (RCT). Twenty-six LBP patients participated in this study. Screening tests were performed and assigned to the experimental group (n=13) and control group (n=13) using a random allocation program. Both groups underwent a lumbar stabilization exercise program. In addition, the experimental group implemented the self-complex exercise program. All interventions were applied three times per week for four weeks. The quadruple visual analog (QVAS), the Korean version of the Oswestry disability index (K-ODI), Korean version of fear-avoidance belief questionnaire (FABQ), static balance ability, TrA thickness, and contraction ratio were compared to evaluate the effect on intervention. Statistical significance was set at 𝛼=.05. Results : Both groups showed significant differences before and after the intervention in QVAS, K-ODI, FABQ, static balance ability, and TrA thickness in contraction (p<.05). In addition, significant differences in K-ODI and FABQ were observed between the experimental group and control group (p<.05). Conclusion : A lumbar stabilization exercise and self-complex exercise program resulted in reduced dysfunctions, psychosocial stability in patients with lumbar instability. Therefore, Lumbar stabilization exercise and self-complex exercise program for patients with lumbar instability are effective method with clinical significance in improving the function and psychosocial stability.

Effects of Eisenia Bicyclis Extracts and Pill on Blood Glucose and Lipid Profile in Streptozotocin-Induced Diabetic Mice (당뇨 생쥐에서 대황 추출물 및 정제환의 혈당과 지질 상태 개선 효과)

  • Cho, Sung-Hee;Park, So-Young;Choi, Sang-Won
    • Journal of Nutrition and Health
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    • v.41 no.6
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    • pp.493-501
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    • 2008
  • The objectives of this study were to investigate the antihyperglycemic and hypolipidmic effects of sea oak(Eisenia bicyclis, EB) in the diabetic state and to examine the appropriateness of formulated EB pill for the effects. The various test materials obtained from EB were included in the experimental diets with 15% fat/0.5% cholesterol and fed to streptozotocin-induced diabetic mice weighing $35.0{\pm}0.7$ g for three weeks but not in the control diet having the same composition. The test materials were EB dry powder, water and ethanol extracts, viscozyme-treated EB water extract(EB enzyme-TR) and formulated pill containing dry powders of the EB, two kinds of seaweed, black soybean, sesame, onion and garlic. BG was measured during feeding period and serum insulin, lipids and thiobarbituric acid reactive substances(TBARS) and intestinal disaccharidase activities were measured at the end of the three weeks of the feeding. BG increase was lower in the EB enzyme-TR group after 10 days of the experimental diet but lower in EB pill group after 15 days compared with the control group. Serum insulin levels were higher in the EB enzyme-TR and EB pill groups. Intestinal maltase but not sucrase activity was higher in EB enzyme-TR fed group than the control group. Serum levels of total cholesterol and triglyceride were reduced by the EB enzyme-TR and EB pill compared with the control diet. HDL-/total cholesterol was increased by all EB test materials. Serum TBARS levels were lower in the EB ethanol extract and EB pill groups than in the control group and tended to be lower in the other EB groups. It is concluded that the EB enzyme-TR is the best among the EB preparations to be utilized as a functional component for improving blood glucose and lipid profile in diabetic subjects in the future. However, the pill containing low level of the EB powder is also regarded as effective and readily usable when formulated with the several other ingredients of the proper composition.(Supported by the RIC Program of MOCIE, Korea).

EXTREME POINTS RELATED TO MATRIX ALGEBRAS

  • Lee, Tae Keug
    • Korean Journal of Mathematics
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    • v.9 no.1
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    • pp.45-52
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    • 2001
  • Let A denote the set {$a{\in}M_n{\mid}a{\geq}0$, $tr(a)=1$}, $St(M_n)$ the set of all states on $M_n$, and $PS(M_n)$ the set of all pure states on $M_n$. We show that there are one-to-one correspondences between A and $St(M_n)$, and between the set of all extreme points of A and $PS(M_n)$. We find a necessary and sufficient condition for a state on $M_{n1}{\oplus}{\cdots}{\oplus}M_{nk}$ to be extended to a pure state on $M_{n1}+{\cdots}+_{nk}$.

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The Study on Camparison Problem Behaviors with Self-conception & Mental Health in Adolescence (청소년의 문제행동과 자아개념$\cdot$정신건강 비교분석 - 서울시내 일부 주$\cdot$야간고등학교를 중심으로)

  • Kim Y.H.;Cho K.J.;Cho M.Y.
    • The Korean Nurse
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    • v.25 no.1 s.134
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    • pp.57-84
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    • 1986
  • On the assumption that nurses must take part actively in realizing ''Bright Society'' and ''Welfare Societ:'', I examined and made a Study of the youth''s self-conception and their state of mental health to offer the basic materials to early detection, tr

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Study on Development of Inter-acceptability Requirements of System Safety (시스템안전의 상호수용에 대한 요구사항 도출 연구)

  • Shin, Duc-Ko;Kim, Gon-Yop;Oh, Seh-Chan;Yoon, Yong-Ki
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.707-710
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    • 2011
  • System safety is defined as the state where the hazard risks due to internal system, interface, operation and maintenance are controlled as acceptable levels. It is represented and evaluated either with the risk level of each risk factor with the consideration of operation environments or with Safety Integrity Level (SIL) which is the system functional safety without considering application environments. The assessment results are issued in forms of certificates and they are reused in many cases. However, the conditions and restrictions for different application environments vary in each case, therefore, additional evaluation on the preconditions of assessment in comparison with the actual application environment must be carried out. For the area of train control, TR 50506-1 has been established based on the IEC 62425 (international standard for safety of train control system by RSSB) and EN 50129 (Europe standard) for the further assessment. In this paper, the analysis on TR 5056-1 has been conducted in depth. The purpose of the study is to determine the requirements for inter-acceptability including scope, procedures, principles, examination and suitability. The results can be utilized for the system safety maintenance when new devices or components are introduced in conventional systems.

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