• Korean Journal of Clinical Pharmacy
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• v.23 no.1
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• pp.14-19
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• 2013

Background :긴 측쇄의 트리글리세라이드(long chain triglyceride, LCT)는 대두 또는 홍화씨로부터 제조된 지방유제의 주요 성분이다. 중 측쇄 트리글리세라이드(medium chain triglyceride, MCT)는 LCT와 다른 물리적 성질을 가지고 있다. MCT의 지방산은 LCT의 지방산 보다 작은 분자량을 가지기 때문에 물에 더 잘 녹으며 다른 경로를 통하여 더 빨리 대사된다. Objectives & Methods :본 연구에서는 지방산의 길이에 따른 고영양수액제(total nutrient admixture, TNA)의 안정성을 비교하기 위하여 서로 다른 LCT와 MCT 조성을 가지는 4 가지 TNA 처방의 안정성을 실온 및 냉장 조건에서 측정하였다. Results :그 결과 MCT와 LCT의 혼합 조성의 TNA는 LCT 단독 조성의 TNA 와 유사한 안정성을 나타내었다. MCT와 LCT 혼합 TNA는 LCT 단독 TNA에 비하여 작은 입자크기를 보였지만 외관, 산도, 과산화수소가, 삼투농도, 아연 농도, 니코틴아미드 및 리보플라빈 농도에서는 의미 있는 차이를 보이지 않았다. Conclusion : 따라서 MCT와 LCT의 혼합 TNA는 LCT 단독 조성 TNA에 상응하는 안정성을 가지고 LCT단독 TNA을 대체제로 사용할 수 있다. 결론적으로, TNA의 2가지 타입 모두 3일 동안 실온과 냉장에서 안정하고, MCT와 LCT의 혼합 TNA는 LCT 단독 조성 TNA보다 생리화학적으로 더 안정하므로 환자들에게 좀 더 효과적인 에너지원이 될 것으로 전망된다.

• Perspectives in Nursing Science
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• v.16 no.1
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• pp.12-24
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• 2019

Purpose: This study examined the suitability of using text network analysis (TNA) methodology for topic analysis of academic papers related to nursing. Methods: TNA background theories, software programs, and research processes have been described in this paper. Additionally, the research methodology that applied TNA to the topic analysis of the academic nursing papers was analyzed. Results: As background theories for the study, we explained information theory, word co-occurrence analysis, graph theory, network theory, and social network analysis. The TNA procedure was described as follows: 1) collection of academic articles, 2) text extraction, 3) preprocessing, 4) generation of word co-occurrence matrices, 5) social network analysis, and 6) interpretation and discussion. Conclusion: TNA using author-keywords has several advantages. It can utilize recognized terms such as MeSH headings or terms chosen by professionals, and it saves time and effort. Additionally, the study emphasizes the necessity of developing a sophisticated research design that explores nursing research trends in a multidimensional method by applying TNA methodology.

• Journal of Korean Society of Archives and Records Management
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• v.18 no.1
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• pp.49-77
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• 2018

As the teaching environment of schools has significantly shifted toward using various types of educational contents, the need for the use of educational contents as class resources has increased. Having an archive is an effective way of organizing information that can provide various educational contents. The National Archives (TNA) of the UK has been actively producing and providing educational contents for teachers and students for a long time. The purpose of this study is to analyze in depth the detailed examples and structure of the contents, the process of producing educational contents, and the methods of providing various contents of the TNA, which systematically provides diverse educational contents. It intended to help archivists discover the educational values of archives in providing users with various types of educational contents. Then, the study compared the analysis results with the National Archives of Korea and suggested for its improvement, as well as that of other archives in the country.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8155-8161
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• 2016

The prognostic significance of AgNOR proteins in stage II-III rectal cancers treated with chemoradiotherapy was evaluated. Silver staining was applied to the $3{\mu}m$ sections of parafin blocked tissues from 30 rectal cancer patients who received 5-FU based chemoradiotherapy from May 2003 to June 2006. The microscopic displays of the cells were transferred into the computer via a video camera. AgNOR area (nucleolus organizer region area) and nucleus area values were determined as a nucleolus organizer regions area/total nucleus area (NORa/TNa). The mean NORa/TNa value was found to be $9.02{\pm}3.68$. The overall survival and disease free survival in the high NORa/TNa (>9.02) patients were 52.2 months and 39.4 months respectively, as compared to 100.7 months and 98.4 months in the low NORa/TNa (<9.02) cases. (p<0.001 and p<0.001 respectively). In addition, the prognosis in the high NORa/TNa patients was worse than low NORa/TNa patients (p<0.05). In terms of overall survival and disease-free survival, a statistically significant negative correlation was found with the value of NORa/TNa in the correlations tests. Cox regression analyses demostrated that overall survival and disease-free survival were associated with lymph node status (negative or positive) and the NORa/TNa value. We suggest that two-dimensional AgNOR evaluation may be a safe and usable parameter for prognosis and an indicator of cell proliferation instead of AgNOR dots.

• Journal of Korean Society of Archives and Records Management
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• v.17 no.4
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• pp.87-107
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• 2017

Because of the creation and transfer of born-digital records, file unit-based record description practices have changed fundamentally. In this study, we analyzed the archival description practices of The National Archives (TNA) to maintain intellectual control in the digital records management environment and to support the access to records of users. TNA has created an archival description based on ISAD(G) but, for describing born-digital records, it changed the guideline for descriptive cataloging practices. As the method of ISAD(G) cannot adhere to born-digital records, the next-generation descriptive standard, Records in Contexts (RiC), is still being developed by ICA. In addition to international efforts, we need to build an archival description system that fits our environment, especially because since the year 2000, TNA's online cataloging system has changed and ISAD(G) has been modified in this process. This study also proposed continuous monitoring of digital archival descriptions, provides an integrated approach to analog records and digital content and strengthens experimentation and cooperation toward an uncertain digital future.

• Proceedings of the KIEE Conference
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• 1997.11a
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• pp.209-211
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• 1997

This paper describes the TNA(Transient Network Analyzer) modeling/operating methods and the analysis results of expected overvoltages of 765 kV system in 2005 by the TNA. The power system is expressed as the equivalent inductance of power system, power source, transmission line, switch, and etc. in the TNA. We have examined the overvoltages in the ground fault case, the fault clearing case and the closing/re-closing case. The maximum line-to-line overvoltage is 1.87 p.u., which occurs between SS and SA at the fault clearing case.

• Journal of Microbiology and Biotechnology
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• v.17 no.7
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• pp.1090-1097
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• 2007

Genomic analysis of Thermococcus sp. NA1 revealed the presence of a 3,927-base-pair (bp) family B-type DNA polymerase gene, TNA1_pol. TNA1_pol, without its intein, was overexpressed in Escherichia coli, purified using metal affinity chromatography, and characterized. TNA1_pol activity was optimal at pH 7.5 and $75^{\circ}C$. TNA1_pol was highly thermostable, with a half-life of 3.5h at $100^{\circ}C$ and 12.5h at $95^{\circ}C$. Polymerase chain reaction parameters of TNA1_pol such as error-rate, processivity, and extension rate were measured in comparison with rTaq, Pfu, and KOD DNA polymerases. TNA1_pol averaged one incorrect bp every 4.45 kilobases (kb), and had a processivity of 150 nucleotides (nt) and an extension rate of 60 bases/s. Thus, TNA1_pol has a much faster elongation rate than Pfu DNA polymerase with 7-fold higher fidelity than that of rTaq.

• Proceedings of the KIEE Conference
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• 1992.07b
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• pp.945-948
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• 1992

In this paper, switching overvoltages are analyzed for future 765kv power system using EMTP(Electro Magnetic Transient Program) and compared with TNA (Transient Network Analyzer) study results which was previously undertaken during overseas training in 1980 and 1988. The result shows the maximum of 2.10 PU at midpoint of 310Km transmission line which is higher than those of TNA study by 0.4 PU. The deviation of EMTP result from TNA is caused by limitation of nonlinear representation and also frequency dependent modeling in EMTP. Further analysis are required to get more exact switching overvoltage factors for future KEPCO 765KV system not only by EMTP but also TNA.

• Journal of Microbiology and Biotechnology
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• v.34 no.4
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• pp.969-977
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• 2024

Indigo is a valuable, natural blue dye that has been used for centuries in the textile industry. The large-scale commercial production of indigo relies on its extraction from plants and chemical synthesis. Studies are being conducted to develop methods for environment-friendly and sustainable production of indigo using genetically engineered microbes. Here, to enhance the yield of bioindigo from an E. coli whole-cell system containing tryptophanase (TnaA) and flavin-containing monooxygenase (FMO), we evaluated tryptophan transporters to improve the transport of aromatic compounds, such as indole and tryptophan, which are not easily soluble and passable through cell walls. Among the three transporters, Mtr, AroP, and TnaB, AroP enhanced indigo production the most. The combination of each transporter with AroP was also evaluated, and the combination of AroP and TnaB showed the best performance compared to the single transporters and two transporters. Bioindigo production was then optimized by examining the culture medium, temperature, isopropyl β-D-1-thiogalactopyranoside concentration, shaking speed (rpm), and pH. The novel strain containing aroP and tnaB plasmid with tnaA and FMO produced 8.77 mM (2.3 g/l) of bioindigo after 66 h of culture. The produced bioindigo was further recovered using a simple method and used as a watercolor dye, showing good mixing with other colors and color retention for a relatively long time. This study presents an effective strategy for enhancing indigo production using a combination of transporters.

• Journal of Korean Society of Archives and Records Management
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• v.21 no.1
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• pp.141-161
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• 2021

This study aims to propose an implementation plan for ensuring the digital continuity of university information resources that require the continuous management of temporary and permanent records in digital transformation environments. Thus, the cases of The National Archives (TNA; United Kingdom) and the National Archives of Australia (NAA)'s digital continuity policies were investigated and analyzed, drawing implications for ensuring universities' digital continuity. The process for ensuring digital continuity proposed by TNA was then applied to a university case for the proposal of an implementation plan applicable to university information resources.