• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.1756-1760
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• 2006

LTPS technology based on SLS Crystallization was intensively reviewed. LTPS structure produced by SLS crystallization is composed of much larger grains compared with conventional ELA crystallization structure, which can give higher TFT performances. However, TFT performance uniformity and anisotropy problem should be solved for it to be used in mass production. TFT performance uniformity was from main grain boundary position and could be solved by equal defect area structure $(EDAS^{TM})$. TFT performance anisotropy could be also solved by multi-channel (MC) structure that can make parallel component in perpendicular channel direction. The higher TFT performances from SLS technology can make superior optical and/or electrical properties and has been adopted in mass production successfully.

• Current Industrial and Technological Trends in Aerospace
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• v.5 no.2
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• pp.33-42
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• 2007

위성체 총조립 및 시험(AIT ; Assembly, Integration & Test)을 위한 전기지상지원장비(EGSE ; Electrical Ground Support Equipment)와 위성 임무 준비 및 운용을 위한 관제시스템(MCS ; Mission Control System)의 공동 개발은 미국과 유럽의 위성사업 기관 및 업체에서 지금까지 많은 연구가 되어 왔다. 비록 두 시스템이 다른 목적으로 사용되고 있지만 기술적으로 유사한 기능을 갖는 시스템으로서 많은 공통점과 호환 가능성을 갖고 있다. 두 시스템의 공동 개발은 시스템 개발과 위성 운용 교육 및 준비에 필요한 비용 절감뿐만 아니라 AIT 단계에서 위성운용단계로의 자연스러운 전환이 가능하다. 이는 AIT 단계에서 공통지상시스템 하드웨어 및 운영시스템, 시험/운용 절차서, 위성 데이터베이스의 사전 검증이 이루어지기 때문이다. 또한 위성 운용 요원의 AIT 참여를 통해 공통지상시스템 운용 훈련과 위성 관제 지식 습득이 자연스럽게 이루어 질 수 있다. 이로서 사업 일정과 개발 위험도를 최소화 할 수 있다. 이러한 두 시스템의 공통성과 호환성 및 공통시스템 개발 장점이 있기에 EGSE와 MCS의 공통 기능에 대한 표준화 작업은 1986년 만들어진 COES(Committee for Operations and EGSE Standard)에서 공식적으로 논의되기 시작하여 1994년 CNES와 ESA의 발의로 제정된 ECSS(European Cooperation for Space Standards)를 통해 국제 표준(ISO, CCSDS 등)을 바탕으로 한 지상시스템에 대한 유럽 표준화 작업이 ECSS-E-70 Working Group에서 진행되고 있다. 또한 검증된 지상시스템의 핵심 운영시스템의 소프트웨어 모듈의 재사용을 통해 최근에서 다양한 공통지상시스템이 개발되어 운용되고 있다. 이러한 배경으로 국내에서도 저궤도 위성 개발에서 EGSE 핵심 모듈인 TM/TC 처리 및 Database 관리 모듈을 AIT 단계에서 개발 및 검증 후에 MCS에서의 재사용을 적극적으로 고려하고 있다. 앞으로 국제적인 추세에 따라 AIT 및 지상국간의 기술 및 인력 교류와 핵심모듈 개발을 통한 공통지상시스템 개발의 활발한 전개가 예상된다.

• Journal of the Korean Society of Clothing and Textiles
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• v.16 no.2
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• pp.245-254
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• 1992

The purpose of this study was to evaluate the mechanical thermal resistances and comfort properties of ski wear made with vapor-permeable water repellent (VPWR) fabrics and thermal insulation battings. Four types of experimental clothing were made with the combination of two VPWR fabrics (Hipora-$TM^{\circledR}$, Hipora-$CR^{\circledR}$) and two thermal insulation battings ($Viwarm^{\circledR},\;Airseal^{\circledR}$). Thermal resistances of ski wear were objectly evaluated by thermal manikin experiment ($21{\pm}\;2^{\circ}C,\;50{\pm}5\%$ R.H.,0.25 m/sec air velocity) and thermographic accessment ($2{\pm}2^{\circ}C,\;0\%$ R.H.,0.25 m/sec air velocity, and emissivity level : 1). Garment wear tests of ski wear included the measurement of the microclimate (inner temp. and relative humidity) of the experimental clothing by digital thermohygrometer and subject wear sensation using McNall's thermal comfort ratings. CBo values of experimental clothing 4 (Hipora-$CR^{\circledR}+Airseal^{\circledR}$) and 1 (Hipora-$TM^{\circledR}+Viwarm^{\circledR}$) were significantly higher than those of 2 (Hipora-$TM^{\circledR}+Airseal^{\circledR}$) and 3 (Hipora-$CR^{\circledR}+Viwarm^{\circledR}$). Thermal resistances in the points of breast, back, belly, and loin was significantly higher than those of upper am, fore arm, and shank of measuring points on the thermal manikin. According to the color map of the thermogram, the experimental clothing 4 indicated higher surface temperatures than the others showing more yellowish spots on the surface of clothing. Inner temperature of experimental clothing was not significantly different among the four types of ski wear, but relative humidities of experimental clothing were significantly different. Relative humidities of experimental clothing 1 and 3 showed higher than those of 2 and 4. Relative humidity of experimantal clothing was affected largely by the thermal resis- tance of thermal insulation batting materials. The subject wear sensation of experimental clothing 2 and 4 showed lower humidity than the others. Subject wear sensation was affected more by humidity sensation than by thermal sensation.

• Korean Journal of Optics and Photonics
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• v.11 no.3
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• pp.171-178
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• 2000

We present a numerical model which enables to analyze $1.47mu$m amplification band characteristics for thulium doped fluoride fiber amplifiers. We focused on upconversion pumping scheme, thus many transitions affecting $1.47mu$m band amplification was considered simultaneously. Backward propagating waves and transverse mode were also considered in the model. The parameters for modeling were then acquired using published experimental data and related theories such as Judd-Ofelt theory for radiative transition, empirical energy gap law for non-radiative transition, and McCumber relations for cross-sections. The simulation showed well-matched results with experiment and internal dynamics. amics.

• Macromolecular Research
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• v.15 no.2
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• pp.160-166
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• 2007

Novel multiblock copolymers, based on segmented sulfonated hydrophilic-hydrophobic blocks, were synthesized and investigated for their application as proton exchange membranes. A series of segmented sulfonated poly(arylene ether sulfone)-b-polyimide multiblock copolymers, with various block lengths, were synthesized via the coupling reaction between the terminal amine moieties on the hydrophilic blocks and naphthalene anhydride functionalized hydrophobic blocks. Successful imidization reactions required a mixed solvent system, comprised of NMP and m-cresol, in the presence of catalysts. Proton conductivity measurements revealed that the proton conductivity improved with increasing hydrophilic and hydrophobic block lengths. The morphological structure of the multiblock copolymers was investigated using tapping mode atomic force microscopy (TM-AFM). The AFM images of the copolymers demonstrated well-defined nanophase separated morphologies, with the changes in the block length having a pronounced effect on the phase separated morphologies of the system. The self diffusion coefficient of water, as measured by $^1H$ NMR, provided a better understanding of the transport process. Thus, the block copolymers showed higher values than Nafion, and comparable proton conductivities in liquid water, as well as under partially hydrated conditions at $80^{\circ}C$. The new materials are strong candidates for use in PEM systems.

• Herbal Formula Science
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• v.30 no.3
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• pp.175-182
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• 2022

Objective : This study aims to investigate the active ingredients and potential mechanisms of the beneficial herb on human cancers such as the liver by employing network pharmacology. Methods : Ingredients and their target information was obtained from various databases such as TM-MC, TTD, and Drugbank. Related protein for liver cancer was retrieved from the Comparative Toxicogenomics Database and literature. A hypergeometric test and gene set enrichment analysis were conducted to evaluate associations between protein targets of red ginseng (Panax ginseng C. A. Meyer) and liver cancer-related proteins and identify related signaling pathways, respectively. Network proximity was employed to identify active ingredients of red ginseng on liver cancer. Results : A compound-target network of red ginseng was constructed, which consisted of 363 edges between 53 ingredients and 121 protein targets. MAPK signaling pathway, PI3K-Akt signaling pathway, p53 signaling pathway, TGF-beta signaling pathway, and cell cycle pathway was significantly associated with protein targets of red ginseng. Network proximity results indicated that Ginsenoside Rg1, Acetic Acid, Ginsenoside Rh2, 20(R)-Ginsenoside Rg3, Notoginsenoside R1, Ginsenoside Rk1, 2-Methylfuran, Hexanal, Ginsenoside Rd, Ginsenoside Rh1 could be active ingredients of red ginseng against liver cancer. Conclusion : This study suggests that network-based approaches could be useful to explore potential mechanisms and active ingredients of red ginseng for liver cancer.

• Journal of Sasang Constitutional Medicine
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• v.35 no.4
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• pp.10-22
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• 2023

Objectives The aim of this study is to explore the mechanism of action and target diseases of Sasang constitutional prescriptions using a multiscale interactome approach. Methods The compound and target information of Sasang constitutional prescriptions were retrieved from various databases such as the TM-MC, STITCH, and TTD. Key targets for Sasang constitutional prescriptions were identified by selecting the top 100 targets based on the number of simple paths within the constructed network. Diffusion profiles for Sasang constitutional prescriptions and diseases were calculated based on a biased random walk algorithm. Potential diseases and key mechanisms of Sasang constitutional prescriptions were identified by analyzing diffusion profiles. Results We identified 144 Sasang constitutional prescriptions and their targets, finding 80 herbs with effective biological targets. A cluster analysis based on selecting up to 100 key targets for each prescription revealed a more cohesive grouping of prescriptions according to Sasang constitution. We then predicted potential diseases for 62 Sasang constitutional prescriptions using diffusion profiles calculated on a multiscale interactome. Finally, our analysis of diffusion profiles revealed key targets and biological functions of prescriptions in obesity and diabetes. Conclusions This study demonstrates the effectiveness of a multiscale interactome approach in elucidating the complex mechanisms and potential therapeutic applications of prescriptions in Sasang constitutional medicine.

• The Journal of Korean Academy of Prosthodontics
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• v.47 no.1
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• pp.70-81
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• 2009

Statement of problem: The position and length of cantilever influence on the stress distribution of implants, superstructure and bone. In edentulous mandible, implant-supported cantilever prostheses that based 4 or 6 implants between mental foramens has been attempted. Excessive bite force loaded at cantilever prosthesis causes bone resorption and breakage of superstructure prosthesis around posterior implants. To complement the cantilever length of conventional prosthesis, In 1992, (McCartney) introduced "cantilever-rest-implant" and Malo reported "All-on-Four" in 2003. Purpose: Analyze and compare the stress distribution of conventional cantilever prostheses with rest implant and All-on-$Four^{TM}$ implant prostheses. Material and method: The external loads(300 N vertically, 75 N horizontally) are applied to first molar area. The stress value, stress distribution and aspect of stress dispersion are analyzed by three-dimensional finite element analysis program, ANSYS ver. 10.0. Results: 1. The rest implant and "All-on-Four" implant system are superior to conventional cantilever prostheses to reduce stress on the bone and the superstructure around implants. 2. The rest implant was of the greatest advantage to stress distribution on bone, implant and superstructure. 3. With same number of implants, distally tilted implants are preferred to conventional cantilever prostheses for reducing the length of cantilever.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.46 no.2
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• pp.195-204
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• 2020

The purpose of this study was to investigate the effects of 14 Chung-bu medicinal materials described in the Dongui Bogam on inflammatory cytokine production in HaCaT human keratinocyte cells. In order to confirm this possibility, we screened inhibition activity of 17 cytokines using Bio-Plex Pro^TM Human Cytokine 17-plex assay in HaCaT cell lines. Of the 14 Chung-bu medicinal materials, Holotrichia (Ho) and Scorpio (Sc) exerted inhibitory effects on interleukin (IL)-5 production; Ho, Mantidis Ootheca (MO), and Hirudo (Hi) exerted inhibitory effects on IL-6 production; Ho, MO, Lumbricus (Lu), Hi, and Meretricis Concha (MC) showed significant inhibitory effects on IL-8 production; Gecko (Ge), Bombycis Faeces (BF), Cicadidae Periostracum (CP), and MC showed significant inhibitory effects on IL-13 production; and Testudinis Chinemis Plastrum et Carapax (TCPC), BF, and Lu exerted significant inhibitory effects on MIP-1β production. Results indicated that the Chung-bu medicinal materials might be a good candicate as potential anti-inflammatory agents for inhibition of skin inflammation. However, further investigations on these materials, including mechanistic studies, should be carried out to validated the effects in human skin equivalent models of dermatitis.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.31 no.6
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• pp.510-518
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• 2009

Purpose: In this study, we analyzed and compared the anatomical position of the mandibular canal in normal occlusion and mandibular prognathism patients. Patients and Methods: Computed tomography image from 58 patients were divided into normal occlusion group and mandibular prognathism group, and each measurement were taken in the each measuring points(2nd premolar, 1st molar, 2nd molar, 3rd molar, ramus). Measurements were statistically analyzed by student's t-test. Results: BC (Thickness of the buccal cortex) value was 2.3~2.7 mm, CB (Distance from the canal to the lingual aspect of the buccal cortex) value was 1.3~4.3 mm, MC (Diameter of the canal) value was 3.2~3.8 mm, LI (Distance from the canal to the lingual aspect of the lingual cortex) value was 2.0~3.7 mm, TM (Thickness of the total mandible) value was 9.5~12.9 mm and CM (Distance from the canal to the inferior border of the mandible) value was 6.9~17.5 mm. Conclusion: In the comparison between two groups, there was statistically significant difference in CB value of 2nd, 3rd molar between normal occlusion and mandibular prognathism, and other value in the rest of the measuring points didn't show statistically significant difference.