• Title/Summary/Keyword: THz

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Terahertz (THz) imaging technology for therapeutic and diagnostic applications of cancer incorporating with radiopharmaceutical fields

  • Min, Sun-Hong;Cho, Ilsung;Park, Chawon;Jung, Wongyun;Hwang, Won Taek;Kim, Minho;Lee, Kyo Chul;Lee, Yong Jin;Lim, Sang Moo;Hong, Bong Hwan
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.5 no.2
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    • pp.120-128
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    • 2019
  • Radiopharmaceuticals include therapeutic radiopharmaceuticals and diagnostic radiopharmaceuticals. Therapeutic radiopharmaceuticals are administered to the body and ingested at specific organs to detect radiation emitted from the site and to construct an image to diagnose the disease. Diagnostic radiopharmaceuticals are used to treat diseases by killing cells with radiation emitted from radiopharmaceuticals, such as cancer cells, vascular endothelial cells, arthritis, and Alzheimer's disease. The application possibilities of terahertz imaging technology for the combination of radiopharmaceuticals and molecular imaging medicine are discussed and experimental methods are presented. Terahertz imaging is expected to be a powerful technique because of the effective piercing feasibility, which enables to perform safe and high resolutive imaging. To investigate the response of cell to the terahertz wave, both the pulsed and CW THz wave systems are employed. THz imaging of a rat's paraffin-embedded epithelial cell with tumor is studied in advance.

THz Optical Properties of Pr3+-Doped Selenide Glasses (Pr3+ 도핑된 셀레나이드 유리의 테라헤르츠 광학 특성)

  • Kang, Seung Beom;Chung, Dong Chul;Kwak, Min Hwan
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.30 no.11
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    • pp.745-750
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    • 2017
  • Terahertz time-domain spectroscopy has been used to study the optical properties of $Pr^{3+}-doped$ selenide glasses. The complex refractive indexes of $Pr^{3+}-selenide$ glasses were measured in a frequency range from 0.3 to 1.5 THz. The real and imaginary refractive indexes increased with increasing frequency and $Pr^{3+}$ ion concentration. The obtained result indicated that the phonon modes of the $Pr^{3+}-doped$ selenide glasses shift to lower frequencies with the concentration of $Pr^{3+}$ ions. The theory of far-infrared absorption in amorphous materials was used to analyze the results. The measured data showed that the disorder-induced terahertz absorption increased with increasing $Pr^{3+}$ ion concentration.

Outage Probability for Cooperative Nano Communication in the THz Gap Frequency Range

  • Samarasekera, A. Chaminda J.;Shin, Hyundong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.1
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    • pp.102-122
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    • 2017
  • Nanotechnology has provided a set of tools that the engineers can use to design and manufacture integrated nano devices, which are capable of performing sensing, computing, data storing and actuation. One of the main hurdles for nano devices has been the amount of power that it can generate for transmission of data. In this paper, we proposed cooperative nano communication in the Terahertz (THz) Gap frequency band to increase the range of transmission. Outage probability (OP) performances for the proposed cooperative nano communication networks in the THz band (0.1 - 10THz) have been evaluated for the following scenarios; A) A single decode-and-forward (DF) relay over independent identically distributed (i.i.d.) Rayleigh fading channels, B) DF multi-relay network with best relay selection (BRS) over i.i.d. Rayleigh fading channels, and C) DF multi-relay network with multiple hops with BRS over i.i.d. Rayleigh fading channels. The results show that the transmission distance can be improved significantly by employing DF relays. Also, it is shown that by increasing the number of hops in a relay the OP performance is marginally degraded. The analytical results have been verified by Monte-Carlo simulation.

Diffraction-Limited High-Power Single-Cycle Terahertz Pulse Generation in Prism-Cut LiNbO3 for Precise Terahertz Applications

  • Baek, In Hyung;Kang, Bong Joo;Jeong, Young Uk;Rotermund, Fabian
    • Journal of the Optical Society of Korea
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    • v.18 no.1
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    • pp.60-64
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    • 2014
  • We report the generation of 3.3-mW single-cycle terahertz (THz) pulses at 1-kHz repetition rate via optical rectification in MgO-doped prism-cut stoichiometric LiNbO3. Efficient pulse-front tilting of 800-nm pulses was realized by an optimized single-lens focusing scheme for radially-symmetric propagation of THz beams. In this geometry, nearly-diffraction-limited THz Gaussian beams with electric field strength as high as 350 kV/cm were generated. The pump-to-THz energy conversion efficiency of $1.36{\times}10^{-3}$ and the extremely high signal-to-noise ratio of ~1:15000 achieved are among the best results for 1-kHz single-cycle terahertz pulse generation ever demonstrated in room temperature operation.

Periodically Poled BaTiO3: An Excellent Crystal for Terahertz Wave Generation by Cascaded Difference-frequency Generation

  • Li, Zhongyang;Yuan, Bin;Wang, Silei;Wang, Mengtao;Bing, Pibin
    • Current Optics and Photonics
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    • v.2 no.2
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    • pp.179-184
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    • 2018
  • Terahertz (THz) wave generation by periodically poled $BaTiO_3$ (PPBT) with a quasi-phase-matching (QPM) scheme based on cascaded difference-frequency generation (DFG) is theoretically analyzed. The cascaded DFG processes comprise cascaded Stokes and anti-Stokes processes. The calculated results indicate that the cascaded Stokes processes are stronger than the cascaded anti-Stokes processes. Compared to a noncascaded Stokes process, THz intensities from $20^{th}$-order cascaded Stokes processes increase by a factor of 30. THz waves with a maximum intensity of $0.37MW/mm^2$ can be generated by $20^{th}$-order cascaded DFG processes when the optical intensity is $10MW/mm^2$, corresponding to a quantum conversion efficiency of 1033%. The high quantum conversion efficiency of 1033% exceeds the Manley-Rowe limit, which indicates that PPBT is an excellent crystal for THz wave generation via cascaded DFG.

Terahertz time domain spectroscopy of GdBCO superconducting thin films

  • Ji, Gangseon;Park, Woongkyu;Lee, Hyoung-Taek;Song, Chang-Yun;Seo, Choongwon;Park, Minjo;Kang, Byeongwon;Kim, Kyungwan;Kim, Dai-Sik;Park, Hyeong-Ryeol
    • Progress in Superconductivity and Cryogenics
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    • v.21 no.1
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    • pp.15-17
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    • 2019
  • We present terahertz optical properties of $GdBa_2Cu_3O_{7-x}$ (GdBCO) superconducting thin films. GdBCO films with a thickness of about 105 nm were grown on a $LaAlO_3$ (LAO) single crystal substrate using a conventional pulsed laser deposition (PLD) technique. Using an Ar ion milling system, the thickness of the GdBCO film was reduced to 58 nm, and its surface was also smoothened. Terahertz (THz) transmission spectra through two different GdBCO films are measured over the range between 0.2 and 1.5 THz using THz time domain spectroscopy. Interestingly, the THz transmission of the thinner GdBCO film has been increased to six times larger than that of the thicker one, while the thinner film is still maintaining its superconducting property at below 90 K.

Dual-function Dynamically Tunable Metamaterial Absorber and Its Sensing Application in the Terahertz Region

  • Li, You;Wang, Xuan;Zhang, Ying
    • Current Optics and Photonics
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    • v.6 no.3
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    • pp.252-259
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    • 2022
  • In this paper, a dual-function dynamically tunable metamaterial absorber is proposed. At frequency points of 1.545 THz and 3.21 THz, two resonance peaks with absorption amplitude of 93.8% (peak I) and 99.4% (peak II) can be achieved. By regulating the conductivity of photosensitive silicon with a pump laser, the resonance frequency of peak I switches to 1.525 THz, and that of peak II switches to 2.79 THz. By adjusting the incident polarization angle by rotating the device, absorption amplitude tuning is obtained. By introducing two degrees of regulation freedom, the absorption amplitude modulation and resonant frequency switching are simultaneously realized. More importantly, dynamic and continuous adjustment of the absorption amplitude is obtained at a fixed resonant frequency, and the modulation depth reaches 100% for both peaks. In addition, the sensing property of the proposed MMA was studied while it was used as a refractive index sensor. Compared with other results reported, our device not only has a dual-function tunable characteristic and the highest modulation depth, but also simultaneously possesses fine sensing performance.