• 대한본초학회지
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• 제30권5호
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• pp.15-21
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• 2015

Objectives : Methicillin-resistantStaphylococcus aureus(MRSA) is a human pathogen. New antibacterial agents are needed to treat MRSA-related infections. This study investigated the antibacterial activity of EtOH 70% extracts ofTonghyeonipal-dan(THD) which prescription is composed of oriental medicine against MRSA.Methods : The antibacterial activity of THD was evaluated against MRSA strains by using the Disc diffusion method, broth microdilution method, Checkerboard dilution test, and Time-kill test; its mechanism of action was investigated by bacteriolysis, detergent or ATPase inhibitors were used.Results : The minimum inhibitory concentration (MIC) of THD is 1,000~2,000 μg/mL against MRSA. In the checkerboard dilution test, fractional inhibitory concentration index (FICI) of THD in combination with antibiotics indicated synergy or partial synergism againstS. aureus. Furthermore, a time-kill assay showed that the growth of the tasted bacteria was considerably inhibited after 24 h of treatment with the combination of THD with selected antibiotics. For measurement of cell membrane permeability, THD 500 μg/mL along with concentration of Triton X-100 (TX) and Tris-(hydroxymethyl) aminomethane (TRIS) were used. In the other hand, N,N-dicyclohexylcarbodimide (DCCD) and Sodium azide (NaN3) were used as an inhibitor of ATPase. TX, TRIS, DCCD and NaN3 cooperation againstS. aureusshowed synergistic action.Conclusions : Accordingly, antimicrobial activity of THD was affected by cell membrane and inhibitor of ATPase were assessed. These results suggest that THD has antibacterial activity, and that THD extract offers great potential as a natural antibiotic against MRSA.

• Journal of Power Electronics
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• 제19권6호
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• pp.1496-1504
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• 2019

This paper proposes a new THD reduction algorithm for modular multilevel converters (MMCs) with offset voltage injection operated in nearest level modulation (NLM). High voltage direct current (HVDC) is actively introduced to the grid connection of offshore wind powers, and this paper deals with a voltage generation technique with an MMC for wind power generation. In the proposed method, third harmonic voltage is added for reducing the THD. The third harmonic voltage is adjusted so that each of the pole voltage magnitudes maintains a constant value with a maximum number of (N+1) levels, where N is the number of sub-modules per arm. By using the proposed method, the THD of the output voltage is mitigated without increasing the switching frequency. In addition, the proposed method has advantageous characteristics such as simple implementation. As a part of this study, this paper compares the THD results of the conventional method and the proposed method with offset voltage injection to reduce the THD. In this paper, simulations have been carried out to verify the effectiveness of the proposed scheme, and the proposed method is implemented by a HILS (Hardware in the Loop Simulation) system. The obtained results show agreement with the simulation results. It is confirmed that the new scheme achieved the maximum level output voltage and improved the THD quality.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2003년도 춘계전력전자학술대회 논문집(1)
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• pp.323-326
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• 2003

본 논문에서는 THD 개선을 위한 단순한 구조의 단일 단 PFC를 제안하고 벅 컨버터에 적용하였다. 제안한 회로는 밸리-필 정류회로와 부스팅을 위한 인덕터를 결합하여 단일 능동 소자로 DC/DC 변환 과 PFC를 동시에 수행한다. 제안된 회로에서의 입력전류 모양은 입력전압조건과 PWM 스위칭 시간에 관계되고, 부스팅 인덕터에 의해 능동스위치 차단시간동안 입력 전류를 제어하여 THD를 개선한다. 부스팅 인덕터 채용에 따른 동작해석과 최적 THD를 위한 인덕터를 선정하고 100W출력 단일 단 컨버터를 설계, 제작하였다. 실험에 의한 측정된 결과로 제안된 컨버터의 타당성을 검증하였다.

• 한국초지조사료학회지
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• 제35권3호
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• pp.238-244
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• 2015

Three growing wethers were used to investigate the differences in nitrogen (N) retention, blood plasma metabolite concentration and energy-yielding nutrient supply to muscle and adipose tissue. The wethers were fed one of three diets: timothy hay with concentrate (THD), Italian ryegrass with concentrate (IRD), and rice straw with concentrate (RSD) for 11 days. The experimental diets were adjusted to the animals to provide 100 g of daily gain. The triglyceride (TG) concentration of blood plasma in arterial and portal veins was higher with THD and IRD than with RSD. Conversely, the available amount of TG in tissues was higher with IRD. The daily amount of glucose and non-esterified fatty acids (NEFA) supplied to muscle tissue and adipose tissue was numerically higher with THD than IRD or RSD. Although N retention did not differ among the diets, it was numerically higher with THD than with IRD or RSD. The results suggest that the difference in the amount of glucose and NEFA delivered to muscle tissue may reflect the N retention in response to forage based diets.

• Journal of Electrical Engineering and Technology
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• 제12권1호
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• pp.78-90
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• 2017

This paper presents the design of closed loop controllers operating a single-phase AC-DC three-level converter for improving power quality at AC mains. Closed loop inhibits outer voltage controller and inner current controller. Simulations of three level converter with three different voltage and current controller combinations such as PI-Hysteresis, Fuzzy-Hysteresis and Fuzzy tuned PI-Hysteresis are carried out in MATLAB/Simulink. Performance parameters such as input power factor and source current total harmonic distortion (THD) are considered for comparison of the three controller combinations. The fuzzy-tuned PI voltage controller with hysteresis current controller combination provides a better result, with a source-current THD of 0.93% and unity power factor without any source side filter for the three level converter. For load variations of 25% to 100%, a THD of less than 5% is obtained with a maximum value of only 1.67%. Finally, the fuzzy-tuned PI voltage with hysteresis controller combination is implemented in a Xilinx Spartan-6 XC6SLX25 FPGA board for experimental validation of power quality enhancement. A prototype 100 W, 0-24-48 V as output converter is considered for the testing of controller performance. A source-current THD of 1.351% is obtained in the experimental study with a power factor near unity. For load variations of 25% to 100%, the THD is found to be less than 5%, with a maximum value of only 2.698% in the experimental setup which matches with the simulation results.

• Nutrition Research and Practice
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• 제8권1호
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• pp.103-111
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• 2014

This study aims to determine the effect of a trained dedicated dietitian on clinical outcomes among Lebanese hemodialysis (HD) patients: and thus demonstrate a viable developing country model. This paper describes the study protocol and baseline data. The study was a multicenter randomized controlled trial with parallel-group design involving 12 HD units: assigned to cluster A (n = 6) or B (n = 6). A total of 570 patients met the inclusion criteria. Patients in cluster A were randomly assigned as per dialysis shift to the following: Dedicated Dietitian (DD) (n = 133) and Existing Practice (EP) (n = 138) protocols. Cluster B patients (n = 299) received Trained Hospital Dietitian (THD) protocol. Dietitians of the DD and THD groups were trained by the research team on Kidney Disease Outcomes Quality Initiative nutrition guidelines. DD protocol included: individualized nutrition education for 2 hours/month/HD patient for 6 months focusing on renal osteodystrophy and using the Trans-theoretical theory for behavioral change. EP protocol included nutrition education given to patients by hospital dietitians who were blinded to the study. The THD protocol included nutrition education to patients given by hospital dietitian as per the training received but within hospital responsibilities, with no set educational protocol or tools. Baseline data revealed that 40% of patients were hyperphosphatemics (> 5.5 mg/dl) with low dietary adherence and knowledge of dietary P restriction in addition to inadequate daily protein intake ($58.86%{\pm}33.87%$ of needs) yet adequate dietary P intake ($795.52{\pm}366.94$ mg/day). Quality of life (QOL) ranged from 48-75% of full health. Baseline differences between the 3 groups revealed significant differences in serum P, malnutrition status, adherence to diet and P chelators and in 2 factors of the QOL: physical and social functioning. The data show room for improvement in the nutritional status of the patients. The NEMO trial may be able to demonstrate a better nutritional management of HD patients.

• 대한전기학회논문지:전력기술부문A
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• 제52권4호
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• pp.177-177
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• 2003

We have proposed the dimming controller using the AC chopper technique. The AC chopper changes the amplitude of the input source voltage with the same frequency. The conventional dimming controller is operated by controlling voltage phase with the triac. It has bad characteristics of the input current THD and the input power factor But the dimming controller using the ac chopper technique has a low current THD and a good power factor. The developed dimming controller is consist of the IGBT and the low pass filter. The system is operated by the variation circuit of the input source voltage and the microprocessor.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 C
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• pp.1130-1132
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• 1999

This paper presents the feature extraction of fault current related to the multi-shot reclosing scheme in the power distribution system. Fourier transform is used to extract the feature of the fault current waveform in the case of the temporary fault and the permanent fault. After the waveform is analyzed using Fourier transform, the magnitude spectrum and the relative variation of THD are calculated. These results are that the relative variation of THD is great in the temporary fault and is little in the permanent fault.

• 한국음향학회지
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• 제19권1호
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• pp.84-88
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• 2000

본 논문에서는 저전압에서 동작하는 CMOS 아날로그 4상한 멀티플라이어를 설계하였다. 제안된 멀티플라이어는 2개의 완전 차동 트랜스컨덕터로 구성되고 공급 전압을 VT+2VDS,sat+VDS,triode로 낮게 유지할 수 있다. 설계된 아날로그 4상한 멀티플라이어는 1.2V 공급전압에서 0.25㎛ CMOS n-well 공정 파라미터를 이용하여 HSPICE 시뮬레이션 하였다. 시뮬레이션 결과 0.7VP-P 최대 입력에서 THD는 1.28%이다.

• 한국전자통신학회논문지
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• 제12권6호
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• pp.1035-1042
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• 2017

본 논문에서는 복잡한 전관방송 장비와 케이블을 용이하게 운용하고, 확장 및 증설할 수 있도록 전력선 통신을 이용한 전관방송 시스템을 개발하였다. 전력선 통신 기반 전관방송 시스템은 디지털 스트리밍 변조 방식을 적용한 제어 보드와 스피커 보드로 구현되었으며, 오디오 최대 출력, 오디오 채널 응답 시간, 오디오 출력 SNR, 그리고 오디오 출력 THD+N에 대한 성능 측정을 실시하여 만족스러운 결과를 확인할 수 있었다.