• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.5
• /
• pp.2297-2302
• /
• 2014

Objective: To evaluate early treatment for extranodal natural killer/T cell lymphoma (ENK/TCL) in China and provide reference for clinical treatment of these patients. Methods: Computer-based retrieval was performed in PubMed, CNKI, CBM, VIP and WanFang Data to search for randomized controlled trials (RCTs) of treatment for early ENK/TCL, and a meta-analysis was conducted with RevMan 5.0 software. Results: A total of 11 RCTs, including 871 patients, were selected, of which the first radiotherapy had a higher complete response (CR) than the first chemotherapy [OR=14.16, 95%CI (8.68, 23.10), P<0.00001] and CR was not different between combined treatment group and radiotherapy group [OR=1.86, 95%CI (0.47, 3.58), P=0.61], but long-term survival rate was higher with combined treatment[OR=1.88, 95%CI (1.09, 3.19), P=0.02]. No difference in survival rate was observed between radio-chemotherapy and chemo-radiotherapy groups [OR=1.11, 95%CI (0.73, 1.69), P=0.63]. Conclusions: Radiotherapy is of great significance in the treatment of early ENK/TCL, but combined therapy could further enhance long-term survival rate of patients. This conclusion still requires further confirmation using RCTs with high quality and large sample size.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.10
• /
• pp.6788-6798
• /
• 2015

In recent high speed rail way, the operating speed of train is enhanced and the introduction of EMU train vehicles is increased. In addition, as expected the demand of the concrete slab track and the trend of design cross-section reduction, the clear behavior of evaluation of internal slab layer is demanded about the variation of design load and speed. The purpose of this study is to evaluate and identify the mechanical behavior pattern of concrete slab track and track-road bed with the variation of axle load and train speed. To this end, the behavior of TCL and HSB was evaluated in according to the variation of axle load and speed. And the analysis results and the data measured TCL strain sensor, which was embedded in TCL slab under installation on Honam high speed railway, was analyzed. The analysis result shows that the strain are increasing in according to the speed-up of train, and line regression was obtained from measured data. Analysis data of the state of bonding condition of slab layer and measured data was analyzed. It is conducted that the TCL layer stress of HEMU 430X, which of axle load, is lighter was similar to the stress of KTX-Honam, the standard deviation of measured stress is dramatically increased.

• Journal of the Korean Society for Railway
• /
• v.17 no.4
• /
• pp.270-280
• /
• 2014

In this study, to examine the causes of cracks in continuously reinforced concrete tracks (CRCTs) and the main factors affecting cracking, a field survey on the status of cracks and crack patterns in the Gyeong-bu high speed line was conducted, and the crack patterns of CRCT due to the temperature difference between the top of the slab (TCL) and the bottom of the subbase (HSB) and the drying shrinkage of concrete were predicted by a nonlinear finite element model considering the structure of CRCT. The results of the numerical analysis show that cracks will be developed at the interface between the sleeper and the TCL, and under the sleeper due to the temperature difference and concrete shrinkage. This corresponds well to the crack locations found in the field. Also, it is found that the most significant factors are the coefficient of thermal expansion with respect to the temperature difference, and the drying shrinkage strain with respect to shrinkage. According to the results, the reinforcement ratio should be carefully determined considering the structures of CRCT because the crack spacing is not always proportional to the reinforcement ratio due to the sleepers embedded in the TCL.

• NEWSLETTER 전기공업
• /
• no.97-15 s.184
• /
• pp.24-26
• /
• 1997

• Journal of Power System Engineering
• /
• v.13 no.5
• /
• pp.46-51
• /
• 2009

Recently, the shock resistance and dynamic characteristics of hard disk drives have become more important due to their highly increased storage density and miniaturization. In this study, we have developed an ANSYS/Mechanical/LS-DYNA based HDD vibration/shock simulation tool for design engineers. This simulation tool using ANSYS APDL can produce a parametric finite element modeling of HDD automatically and has GUI-based applications using the script program language Tcl/Tk. In the present tool, we adopt the reliable methodology of vibration/shock simulation, which is experimentally verified. It is expected that this simulation tool can make the repetitive computational efforts for the shock-proof design of HDD drastically reduced.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.20 no.5
• /
• pp.605-613
• /
• 2007

The purpose of this study is to develop a structural analysis system of LNG pump tower structure. The system affords to build optimized finite element model and procedure of the pump tower structure. The pump tower structure is one of the most important components of LNG (liquefied natural gas) carriers. The pump tower structure is subject to sloshing load of LNG induced by ship motion depending on filling ratio. Three typer of loading components, which are thermal, inertia and self-gravity are considered in the analysis. The finite element analysis is performed with ANSYS commercial code. The failure of each members can be evaluated of API unity and punching shear in ABS rule. The GUI is newly developed using Tcl/tk script language. All these design and analysis procedures are embedded in to the analysis system successfully.

• Journal of Plant Biotechnology
• /
• v.30 no.3
• /
• pp.251-255
• /
• 2003

An efficient system for in vitro bulblet formation of Lilium oriental hybrids(cvs). Casa Blanca and Siberia is described. Transverse thin cell layer(tTCL)(1mm thick) explants of 'Casa Blanca' formed bulblets at a frequency of 97.7％ when cultured on Murashige and Skoog (MS) medium supplemented with 1mg/L 2,4 dichlorophenoxyacetic acid(2,4-D) (On average 15.6 bulblets were formed per explant). The frequency of bulblet formation was drastically reduced when the explant ghickness was thinner than 1 mm. Explants from the outermost layer of bulb scale produced greater frequency of bulblet formation than middle or innermost layer. Among auxins supplemented to culture medium at 1 mg/L, 2,4-D led to greater frequency of bulblet formation on explants than dicamba, picamba, or phenylacetic acid(PAA). tTCL explants from the middle region of the outermost layer bulb scale yielded greater frequency of bulblet formation than the upper or lower region. tTCL stem explants of 'Siberia' formed bulblets at a frequency of 95.3% when cultured on MS medium with 1 mg/L 2,4-D(On average 9.1 bulblets were formed per explant). The system estabilished in this study will be useful for in vitro rapid propagation and genetic transformation of Lilium Oriental hybrids.

• Journal of Life Science
• /
• v.22 no.10
• /
• pp.1330-1338
• /
• 2012

Solvent extracts of Theobroma cacao L. (TCL) were investigated for anti-oxidative and anti-inflammatory effects in order to consider TCL as a functional ingredient for cosmetic products. TCL(A) extract was fractioned according to polarity with $CHCl_3$, EtOAc, n-BuOH, and water. Following TCL(A) fractionation, the electron-donating ability of the n-BuOH and EtOAc solvent fractions (each 100 ${\mu}g/ml$) was about 76.2% and 53.9%, respectively. The superoxide anion radical inhibitory effect of the n-BuOH and EtOAc solvent fractions (each 50 ${\mu}g/ml$) was about 76.09% and 51.4%, respectively. Results of lipid oxidation showed that $Fe^{2+}$ had a greater chelating effect than $Cu^{2+}$. The $Fe^{2+}$ chelating effect of the EtOAc solvent fraction (50 ${\mu}g/ml$) was about 64%. Hyaluronidase inhibition related to the anti-inflammatory effect was 53.0% with EtOAc at 100 ${\mu}g/ml$, while the lipoxygenase inhibitory effect was about 51.32% at 10 ${\mu}g/ml$. The anti-inflammatory activity in the EtOAc fraction inhibited the generation of nitric oxide. Results also showed that iNOS protein expression increased in RAW264.7 cells. In contrast, at 100 ${\mu}g/ml$ EtOAc, iNOS and COX-2 protein expression significantly decreased in LPS-stimulated RAW 264.7 cells.

• The KIPS Transactions:PartC
• /
• v.11C no.4
• /
• pp.463-470
• /
• 2004

ASN.1/GDMO is the management object used in network management of TMN(Telecommunication Management of Network). However, ASN.1/GDMO is not directly used for managing the network, but translated Into a language with object-oriented paradigm. Therefore we need a development environment for handling ASN.1/GDMO. In this paper we present an integrated development environment(IDE) which consists of an editor and a browser. A user manages ASN.1/GDMO elements with GUI. The IDE is implemented with FLEX and BYACC in UNIX. And Objectivity DB is used as the DB and Tcl/Tk is used for developing GUI. This paper shows how the integrated environment of ASN.1 and GDMO works, and that it enables to manage efficiently the network.

• Journal of Pharmacopuncture
• /
• v.11 no.3
• /
• pp.55-66
• /
• 2008

Objective&Methods: The purpose of this study is to observe the effects of HK-1000 Herbal-acupuncture solution at GB34(Yangleungchean) on hyperlipidemia and arteriosclerosis in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological change of liver and aorta. Results: 1. HK-1000 herbal-acupuncture infusion increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1000 group, serum AST and ALT were significantly lower than those of the HG group and saline group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusions: From the above results, it is suggested that HK-1000 herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia and arteriosclerosis.