• Title/Summary/Keyword: T3N0

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Quality of Life Improved with Allergen-removed Rhus Verniciflua Stokes based Traditional Korean Medicine on a Patient with Refractory Rectal cancer : Single Case Report (알러젠 제거 옻나무 추출물 투여로 삶의 질이 개선된 불응성 직장암 환자 1례)

  • Kim, Na-Hee;Park, Jae-Woo;Kim, Kyung-Suk;Jung, Hyun-Sik;Choi, Won-Chul;Yoon, Seong-Woo
    • Journal of Korean Traditional Oncology
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    • v.13 no.1
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    • pp.55-61
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    • 2008
  • Nearly 800,000 new colorectal cancer cases are believed to be occur each year, which account for approximately 10% of all incident cancers, and mortality from colorectal cancer is estimated at nearly 450,000 per year. We report one patient with rectal cancer of stage III. The patient had a rectal cancer(StageIII T3N2M0) and underwent low anterior resection in 2004 followed by chemotherapy and radiotherapy. Lymph node metastases were found in 2005 and the patient was treated by palliative chemotherapy, which could not supress the lymph node metastases increase. The patient visited Kyunghee University East-West Neo Medical Center(KHNMC) in 2006 and was treated using allergen-removed Rhus Verniciflua Stokes(aRVS). Radiotherapy was done simultaneously in 2006. There was no evidence of recurrence since then. The patient showed no side effects. This case report brings forth the importance of a thorough study in rectal cancer in the traditional Korean medical point of view, along with the long-term effect of aRVS.

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Stability Evaluation of Bump Crossing and Loading of Proto-type Mini-Forwarder by Computer Simulation (컴퓨터 시뮬레이션을 이용한 소형 임내차 시작기의 장애물 통과 및 적재 안정성 평가)

  • Park H. K.;Kim K. U.;Shim S. B.;Kim J. W.;Park M. S.;Song T. Y.
    • Journal of Biosystems Engineering
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    • v.30 no.6 s.113
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    • pp.366-372
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    • 2005
  • The objective of this study was to evaluate the bump crossing and loading stability of a proto-type mini-forwarder under development. The evaluation was performed by computer simulation using a multi-body dynamic analysis program, Recur- Dyn 5.21. The proto-type was modeled and its properties such as mass, mass center, and mass moment of inertia were determined using 3D CAD modeler, Solid Edge 8.0. The $\%$ errors of masses, mass center, mass moment of inertia, and vertical motion of the model were within less than $10\%$ and the model's behavior agreed relatively well with those of the proto-type when traversing over a rectangular bump. Using the validated model, bump crossing of the proto-type was simulated and the loading limit was determined. It was found that effects of the shapes of bump on the bump crossing performance was insignificant within the practical heights of bumps. Stability of bump crossing increased with loading. However, loading of longer logs than 2.7 m made the crossing unstable because the ends of logs contacted ground when traversing over the bump. The maximum loading capacity of the proto-type was estimated to be 7.8 kN of 2.7 m long logs.

The effect of different fiber reinforcements on flexural strength of provisional restorative resins: an in-vitro study

  • Kamble, Vaibhav Deorao;Parkhedkar, Rambhau D.;Mowade, Tushar Krishnarao
    • The Journal of Advanced Prosthodontics
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    • v.4 no.1
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    • pp.1-6
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    • 2012
  • PURPOSE. The aim of this study was to compare the flexural strength of polymethyl methacrylate (PMMA) and bis-acryl composite resin reinforced with polyethylene and glass fibers. MATERIALS AND METHODS. Three groups of rectangular test specimens (n = 15) of each of the two resin/fiber reinforcement were prepared for flexural strength test and unreinforced group served as the control. Specimens were loaded in a universal testing machine until fracture. The mean flexural strengths (MPa) was compared by one way ANOVA test, followed by Scheffe analysis, using a significance level of 0.05. Flexural strength between fiber-reinforced resin groups were compared by independent samples t-test. RESULTS. For control groups, the flexural strength for PMMA (215.53 MPa) was significantly lower than for bis-acryl composite resin (240.09 MPa). Glass fiber reinforcement produced significantly higher flexural strength for both PMMA (267.01 MPa) and bis-acryl composite resin (305.65 MPa), but the polyethylene fibers showed no significant difference (PMMA resin-218.55 MPa and bis-acryl composite resin-241.66 MPa). Among the reinforced groups, silane impregnated glass fibers showed highest flexural strength for bis-acryl composite resin (305.65 MPa). CONCLUSION. Of two fiber reinforcement methods evaluated, glass fiber reinforcement for the PMMA resin and bis-acryl composite resin materials produced highest flexural strength. Clinical implications. On the basis of this in-vitro study, the use of glass and polyethylene fibers may be an effective way to reinforce provisional restorative resins. When esthetics and space are of concern, glass fiber seems to be the most appropriate method for reinforcing provisional restorative resins.

Comparison of Motivation for Rehabilitation, Family Support and Adherence to Rehabilitation between Depressive and Non-depressive Stroke Patients (뇌졸중 환자의 우울 유무에 따른 재활동기, 가족지지 및 재활이행 간의 비교)

  • Park, An Suk;Ko, Eun;Kang, Hee Sun
    • The Korean Journal of Rehabilitation Nursing
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    • v.19 no.2
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    • pp.138-147
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    • 2016
  • Purpose: The purpose of this study was to compare motivation for rehabilitation, family support and adherence to rehabilitation and identify factors predicting adherence to rehabilitation between depressive and non-depressive stroke patients. Methods: Stroke patients admitted to rehabilitation hospitals (n=159) participated in the study. Data were collected through self-reported questionnaires including general characteristics, depression, motivation for rehabilitation, family support and adherence to rehabilitation. The data were analyzed by descriptive statistics, t-test, $x^2$ test, Pearson correlation coefficients and logistic regression using the SPSS/WIN 21.0 program. Results: 62.9% of the subjects were identified as depressive patients. Motivation for rehabilitation (F=48.18, p=.020) and adherence to rehabilitation (F=9.68, p=.002) in depressive stroke patients were significantly lower than non-depressive stroke patients. Family support also in depressive group was lower than non-depressive group but there was no statistical significance (F=2.35, p=.127). Motivation for rehabilitation (OR=11.46), family support (OR=1.05) and onset period (less than 2 year)(OR=3.61) predicted the good adherence to rehabilitation in depressive stroke patients. Conclusion: The results of this study indicate that health professionals need to identify factors affecting adherence to rehabilitation and provide a nursing intervention considering the depression especially when caring for stroke patients.

Mechanical Behavior of the Soleus Aponeuroses during Voluntary Contraction Using Magnetic Resonance Imaging Technique (자기공명 영상기법을 이용한 인체 가자미근 건막의 기계학적 특성 연구)

  • Lee, Hae-Dong
    • Korean Journal of Applied Biomechanics
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    • v.17 no.1
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    • pp.121-127
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    • 2007
  • Muscle force produced by muscle fibers is transmitted to bones via tendinous structures(aponeuroses and tendon), resulting in joint(s) movement. As force-transmitting elements, mechanical behavior of aponeuroses and tendon are closely related with the function of muscle-tendon complex. The purpose of this study was to determine strain characteristics of aponeuroses for in-vivo human soleus muscle during submaximal voluntary contractions using an advanced medical imaging technique, velocity-encoded phase-contrast magnetic resonance imaging (VE-PC MRI). VE-PC MRI of the soleus muscle-tendon complex was acquired during submaximal isometric plantarflexion contraction-relaxation cycle (n = 7), using 3.0T Trio MRI scanner(Siemens AG, Malvern, MA). From the VE-PC MRI containing the tissue velocity in superior-inferior direction, twenty regions of interest(20 ROI; 10 on the anterior aponeurosis and 10 on the posterior aponeurosis) were tracked. During the isometric plantarflexion contraction-relaxation cycle, velocity and displacement profiles were different between the anterior and posterior aponeuroses, indicating heterogeneous strain behavior along the length of the leg. The anterior aponeurosis elongated while the posterior aponeurosis shortened during the initial phase of the contraction. Moreover, strain behavior of the posterior aponeurosis was different from that of the Achilles tendon. Possible explanation for the observed variations in strain behavior of aponeuroses was investigated with morphological assessment of the soleus muscle and it was found that the intramuscular tendinous structures significantly vary among subjects. In conclusion, the heterogeneous mechanical behavior of the soleus aponeuroses and the Achilles tendon suggests that the complexity of skeletal muscle-tendon complex should be taken into consideration when modeling the complex for better understanding of its functions.

Basic Studies for the Development of the $NO_2$ Gas Sensor Using Functional Organic Ultrathin Film (기능성 유기 초박막을 이용한 $NO_2$ 가스센서 개발을 위한 기초 연구)

  • Sohn, B.C.;Rim, B.O.;Kim, Y.I.;Sohn, T.W.;Shin, D.M.;Ju, J.B.;Chung, G.Y.;Kim, Y.K.;Kang, W.H.;Lee, B.H.
    • Journal of the Korean Applied Science and Technology
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    • v.12 no.1
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    • pp.125-131
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    • 1995
  • Ultra thin films of Tetra-3-hexadecylsulphamoylcopperphthalocyanine(HDSM-CuPc) were formed on various substrates by Langmuir-Blodgett method, where HDSM-CuPc was synthesized by attaching long-chain alkylamine(hexa-decylamine) to CuPc. The reaction product was identified with FT-IR, UV-visible absorption spectroscopies, elemental analysis and thin layer chromatography. The formation of Ultrathin Langmuir-Blodgett(LB) films of HDSM-CuPc was confirmed by FT-IR and UV-visible spectroscopies. A quartz piezoelectric crystal coated with LB films of HDSM-CuPc was examined as a gas sensor for $N0_2$ gas. HDSM-CuPc LB films were transferred to a quartz crystal microbalance(QCM) in the form of Z-type multilayers. Response characteristics of film-coated QCM to $NO_2$ gas concentrations over a range of $100{\sim}600ppm$ have been tested with a thickness of $5{\sim}20$ layers of HDSM-CuPc. Changes in frequency by adsorption of $NO_2$ were increased With the number of LB layers and $NO_2$ concentration, but the response time was slow.

Influence of operator's experience level on lifespan of the WaveOne Primary file in extracted teeth

  • Saleh, Abdulrahman Mohammed;Tavanafar, Saeid;Vakili-Gilani, Pouyan;Al Sammerraie, Noor Jamal;Rashid, Faahim
    • Restorative Dentistry and Endodontics
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    • v.38 no.4
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    • pp.222-226
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    • 2013
  • Objectives: The aim of this study was to assess the influence of operator experience level on the lifespan of the WaveOne Primary file (Dentsply Maillefer, Ballaigues, Switzerland) in extracted teeth. Materials and Methods: Moderately curved canals of extracted maxillary and mandibular molars were randomly distributed into 2 groups: experienced and inexperienced operators. Ten files were allocated to each group (n = 10). Each canal was prepared until the working length was reached, and the same file was used to prepare additional canals until it separated. The number of canals prepared before file separation was recorded. The fragment length of each file was measured, and the location of the fragment in the canal was determined. Data were statistically analysed using the independent 2-sample t-test. Results: The 2 operators prepared a total of 324 moderately curved canals of maxillary and mandibular molars. There was no significant intergroup difference in the mean number of canals prepared (p = 0.27). The average lifespan of the WaveOne Primary file was 17.1 and 15.3 canals, and the longest lifespan was 25 and 20 canals, when used by experienced and inexperienced operators, respectively. There were no statistically significant intergroup differences in separated fragment length and location. Conclusions: Within the limitations of this study, operator experience level appears to have no effect on the lifespan of the WaveOne Primary file in preparation of moderately curved canals. Single teeth with multiple canals can be prepared safely even by a novice operator by using a single file.

The Effects of Nursing Information at Discharge on Level of Knowledge and Daily Activities of Open Heart Surgery Patient (퇴원시 간호정보제공이 개심수술 환자의 지식과 일상활동에 미치는 효과)

  • Kim Keum Soon;Hah Yang Sook;Yoo Kyung Hee
    • Journal of Korean Public Health Nursing
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    • v.4 no.1
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    • pp.25-35
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    • 1990
  • This study examined the evaluation of the information effects of the teaching on knowledge and daily activities of open heart surgery patients between 2 and 6 weeks after discharge. The subject was 29 patients being taught with teaching materials at discharge as experimental group, 20 patients who received no education as control group among the patients who had undergone open heart surgery in S.N.U.H. And research method was non-equivalent control group non-synchronized quasi-experimental design. As the tool of this study, 30 items of knowledge measurement scale which was extracted among the content of teaching materials to evaluate the effect of education and 28 items of which were designed to measure the daily activities of patients with myocardial infarction for the estimation of the degree of observance in daily activities were used. For data analysis, frequency, t-test, Pearson's correlation coefficient and Cronbach's $\alpha$ were used. The result were as follows; 1. Informations given through teaching materials were effective for increasing the knowledge of the patient with open heart surgery. The knowledge of patients increased to the top level (p<0.05) in 2 weeks after discharge. In control group, the knowledge level of patients did not increase after discharge. 2. The knowledge level daily activity of the experimental group was somewat higher than that of the control group, but there was no significant difference. The score .of the experimental group was 69.66 in 6 weeks after discharge much less than the top level score 112. 3. The correlation between knowledge and daily activities was not significant, suggesting the fact that the increase of knowledge did not influence the daily activities significantly. Recommendation was suggested that; 1) Further studies might be .needed with the increasing numbers of the subjects. 2) Daily activities of the patients with open heart surgery should be investigated for long term period until they recovered normal activities.

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Comparison of mechanical properties of nickel-titanium rotary files: Aurum Blue vs. Aurum Pro (니켈티타늄 전동 파일의 기계적 특성 비교: Aurum Blue vs. Aurum Pro)

  • Kwak, Sang Won;Ha, Jung-Hong;Ahn, Sang Mi;Kim, Hyeon-Cheol
    • The Journal of the Korean dental association
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    • v.57 no.11
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    • pp.672-678
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    • 2019
  • AIM: The purpose of this study was to evaluate and compare the torsional fracture resistances, cyclic fatigue resistance, and bending stiffness of two nickel-titanium (NiTi) rotary instruments made of different heat-treated alloy: Aurum Blue (heat-treated) and Aurum Pro (conventional). Methods: Forty-five Aurum Blue and Aurum Pro NiTi files were selected for the three mechanical tests (n=15). For the torsional resistance test, 3 mm file tip was fixed and the shaft was driven clockwise at 2 rpm until fracture occurred by using a customized device. Cyclic fatigue resistance was evaluated by rotating instruments in artificial canal with dynamic mode. Bending stiffness was tested by observation of the bending moment on attaining a 45° bend. The results were analyzed by student-t tests at a significance level of 95%. The fractured surface of each groups were examined under a scanning electron microscope (SEM). Results: Aurum Blue showed significantly higher toughness, ultimate strength, distortion angle, and number of cycles to failure than those of Aurum Pro (p < 0.05). However, Aurum Blue and Aurum Pro did not differ significantly in terms of bending stiffness. SEM showed typical topographic appearances of the cyclic fatigue and torsional fracture. Conclusions: Under the limitations of this study, heat-treated instruments showed higher flexibility and fracture resistances than conventional NiTi instruments.

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A Case of Primary Lung Cancer Producing Alpha-fetoprotein (알파 태아단백을 분비하는 원발성 폐암 1예)

  • Yu, Ji-Hyun;Ahn, Joong-Hyun;Chung, Han-Hee;Kim, Young-Wook;Yu, Jin-Sok;Kim, Ju-Sang
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.1
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    • pp.72-76
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    • 2012
  • We observed a very rare case of primary lung cancer producing alpha-fetoprotein (AFP). A 70-year-old male with a history of smoking 50 packs per year was diagnosed with large cell carcinoma of the lung. The clinical stage was T2bN3M0 (IIIB), and serum AFP was 23,247 ng/mL. There was no evidence of metastasis to the liver, scrotum or other organs. While undergoing chemotherapy for 1 year, as the cancer progressed the AFP value steadily increased. The patient died of respiratory failure due to pneumonia 12 months after being diagnosed with lung cancer.