• Title/Summary/Keyword: T3N0

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Preoperative Staging in Non-Small Cell Lung Cancer without Lymphadenopathy on Computed Tomogram (흉부 전산화 단층촬영상 임파절종대가 없는 비소세포암 환자에 있어서 술전 병기판정)

  • Cha, Seung-Ick;Kim, Chang-Ho;Park, Jae-Yong;Jung, Tae-Hoon;Chang, Bong-Hyun;Kang, Duk-Sik
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.6
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    • pp.616-623
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    • 1994
  • Objectives: Careful evaluation about mediastinal involvement is important in the management of patients with non-small cell lung cancer. Invasive staging procedure such as mediastinoscopy is advocated because of the unreliability of noninvasive staging methods such as CT, MRI. We compared differences between pre- and postoperative staging in non-small cell lung cancer without lymphadenopathy on CT scan and investigated the methods for more accurate preoperative staging. Methods & Results: 1) Records of a total of 41 patients with preoperative $T_{1-3}N_0M_0$ non-small cell lung cancer were reviewed and the histologic types of tumors were squamous cell carcinoma in 32 cases, adenocarcinoma in 6 cases and large cell carcinoma in 3 cases. Twenty-four cases were central lesions and seventeen cases were peripheral lesions. 2) Among the 32 cases with preoperative $T_2$, 2 cases were identified postoperatively as $T_3$ with invasion of chest wall and among 6 cases with preoperative $T_3$, 1 case was identified postoperatively as $T_4$ with invasion of aorta and pulmonary arteries. 3) After the operation of 35 cases with $T_{1-2}$, 5 cases were $N_1$ and 3 cases were $N_2$ postoperatively. After the operation of 6 cases with $T_3$, 2 cases were $N_1$ and 3 cases were $N_2$ postoperatively. Preoperative $T_3$ showed more intrathoracic lymph node metastases and higher $N_2/N_1$ involvement ratio than preoperative $T_{1-2}$. 4) Complete surgical resections were done in 34 out of 41 cases. Incomplete resection were done in all postoperative $N_2$ tumors. Conclusion: Invasive staging procedures such as mediastinoscopy should be considered in the case of preoperative $T_3$ non-small cell lung cancer even though mediastinal lymphadenopathy is not recognized on the CT scan of the chest.

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The Result of Radiotherapy in Glottic Cancer (성문암의 방사선치료)

  • Cho, Moon-June;Kim, Il-Han;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.3 no.2
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    • pp.131-136
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    • 1985
  • A retrospective analysis of 29 patients with glottic cancer, treated at the Department of Therapeutic Radiology, Seoul National University Hospital. $97\%$ of the patients was male. Of the 29 patients, stage $T_1N_0M_0$ comprised $31\%$, $T_2N_0M_0\;52\%$, and stage $T_3N_0M_0\;14\%$. Local control rate with radical readiotherapy was $78\%$ for stage $T_1N_0M_0,\;60\%$, for stage $T_2N_0M_0$, and $50\%$ for stage $T_3N_0M_),\;57\%$ of the patients with the radiation failure was salvaged by surgery. The overall 3 year survival rate was $89\%$ for the $T_1N_0M_0,\;80\%$ for stage $T_2N_0M_0$, and $50\%$ for stage $T_3N_0M_0$. Among the survivors: $88\%$ of $T_1N_0M_0\;75\%$ of $T_2N_0M_0,\;and\;50\%$ $T_3N_0M_0$ had an intact larynx and natural voice. It is concluded that radiotherapy is a highly effective method as the primary treatment of the early glottic cancer, emphasized on preserving of the larynx and natural voice.

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Comparative Analysis of Three Subgroups in Stage II Stomach Cancer (제2기 위암에서 3 Subgroup간의 비교 분석)

  • Suh Byung Sun;Kim Byung Sik;Kim Yong Ho;Yook Jung-Whan;Oh Sung-Tae;Kim Wan-Soo;Park Kun-Choon
    • Journal of Gastric Cancer
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    • v.1 no.1
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    • pp.32-37
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    • 2001
  • Purpose: Three subgroups of stage II stomach cancer (T1N2M0, T2N1M0, T3N0M0) by UICC-TNM staging system show obvious survival difference to each other, which becomes the pitfall of the current staging system. We analyzed the survival and relapse pattern of stage II stomach cancer patients in three subgroups retrospectively to prove the need for change in staging system. Materials and Methods: From July 1989 to December 1995, curative gastric resection was performed in 1,037 patients with gastric adenocarcinoma, and among them 268 patients ($26\%$) were in stage II. The number in each of subgroups (T1N2M0, T2N1M0, and T3N0M0) were 17, 139 and 112 respectively. Survival and relapse pattern were analyzed and median follow up period was 46 months. Results: The 3-year cumulative survival rates of T1N2M0, T2N1M0, and T3N0M0 were $50\%,\;80\%,\;and\;76\%$ respectively (p=0.001). And the 3-year cumulative survival rates of T1N2M0 was comparable to those of 2 subgroups of stage IIIa (T2N2M0, T3N1M0), $47\%\;and\;45\%$ (p>0.05). Peritoneal recurrence was the most frequent in T3N0M0. And hematogenous spread was more frequent in T2N1M0 while nodal spread was more frequent in T1N2M0. Ten out of 17 cases of T1N2M0 died of recurrence. Most of them showed submucosal tumor with depressed lesion and mean tumor size was 3.3 cm. Conclusions: Up-staging of T1N2M0 should be considered because it has the lowest survival rate and the worst prognosis among the three subgroups of Stage II stomach cancer patients. In early gastric cancer patients with high-risk factors (large tumor size, invasion into the submucosal layer, and lymphatic vessel involvement), lymph node dissection and postoperative adjuvant therapy is recommended in an attempt to prevent recurrence in the form of lymph node metastasis.

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AN ANALOGUE OF THE HILTON-MILNER THEOREM FOR WEAK COMPOSITIONS

  • Ku, Cheng Yeaw;Wong, Kok Bin
    • Bulletin of the Korean Mathematical Society
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    • v.52 no.3
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    • pp.1007-1025
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    • 2015
  • Let $\mathbb{N}_0$ be the set of non-negative integers, and let P(n, l) denote the set of all weak compositions of n with l parts, i.e., $P(n,l)=\{(x_1,x_2,{\cdots},x_l){\in}\mathbb{N}^l_0\;:\;x_1+x_2+{\cdots}+x_l=n\}$. For any element $u=(u_1,u_2,{\cdots},u_l){\in}P(n,l)$, denote its ith-coordinate by u(i), i.e., $u(i)=u_i$. A family $A{\subseteq}P(n,l)$ is said to be t-intersecting if ${\mid}\{i:u(i)=v(i)\}{\mid}{\geq}t$ for all $u,v{\epsilon}A$. A family $A{\subseteq}P(n,l)$ is said to be trivially t-intersecting if there is a t-set T of $[l]=\{1,2,{\cdots},l\}$ and elements $y_s{\in}\mathbb{N}_0(s{\in}T)$ such that $A=\{u{\in}P(n,l):u(j)=yj\;for\;all\;j{\in}T\}$. We prove that given any positive integers l, t with $l{\geq}2t+3$, there exists a constant $n_0(l,t)$ depending only on l and t, such that for all $n{\geq}n_0(l,t)$, if $A{\subseteq}P(n,l)$ is non-trivially t-intersecting, then $${\mid}A{\mid}{\leq}(^{n+l-t-l}_{l-t-1})-(^{n-1}_{l-t-1})+t$$. Moreover, equality holds if and only if there is a t-set T of [l] such that $$A=\bigcup_{s{\in}[l]{\backslash}T}\;A_s{\cup}\{q_i:i{\in}T\}$$, where $$A_s=\{u{\in}P(n,l):u(j)=0\;for\;all\;j{\in}T\;and\;u(s)=0\}$$ and $$q_i{\in}P(n,l)\;with\;q_i(j)=0\;fo\;all\;j{\in}[l]{\backslash}\{i\}\;and\;q_i(i)=n$$.

Effect of Aluminum Sulfate Addition to Litter and Dietary Protein Levels of Broilers on Litter Nitrogen Content (육계에 급여되는 사료중의 단백질 수준과 깔짚 내의 Aluminum Sulfate 첨가가 깔짚 내의 질소 함량에 미치는 영향)

  • Park, I. H.;K. H. Nahm
    • Korean Journal of Poultry Science
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    • v.30 no.2
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    • pp.119-128
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    • 2003
  • The two experiments in this study compared litter nitrogen (N) contents after broiler chicks were raised for 42 days. Experiment I compared litter treated with aluminum sulfate (alum) [Al$_2$(SO$_4$)$_3$ㆍ14$H_2O$] (T$_1$) with nontreated litter (T$_2$) when the broiler chicks were fed the same levels of dietary protein (23% for 0∼3 weeks, 21% for 4∼6 weeks) Experiment 2 compared the alum treated litters of broiler chicks fed high protein diets (T$_3$) having 20.4% protein for 0∼3 weeks and 19.3% for 4∼6 weeks, with lower protein diets (T$_4$) having protein levels of 18.0% for 0∼3 weeks and 17.0% for 4 6 weeks. Each treatment had four replicate cages. As shown in Table 1, T$_1$ had a significantly (P<0.0l) lower pH and significantly (P<0.05) higher total N (TN), NH$_4$-N and inorganic N (IN) than T$_2$. T$_1$ and T$_2$ had similar moisture, organic carbon (OC), NO$_3$-N and organic N (ON). Alum treatment increased available N (AN) significantly (P<0.05) from 13.75$\pm$0.0l mg/g to 14.90$\pm$0.01 mg/g and predicted available N (PAN) significantly (P<0.05) from 15.00$\pm$0.0l to 16.50$\pm$0.02. The C : N ratios were 18.84$\pm$0.40 (T$_1$) and 19.46$\pm$0.10 (T$_2$) while the C : ON ratios were 28.49$\pm$1.15 (T$_1$) and 28.34$\pm$0.20 (T$_2$) although C : N ratios or C : ON ratios did not show any difference between T$_1$ and T$_2$. In Table 2, T$_3$ had significantly (P<0.05) higher moisture, TN, NH$_4$-N, ON and IN than T$_4$, while the pH, OC and NO$_3$-N were similar in both groups. The AN of T$_3$ increased significantly (P<0.05) from 10.99$\pm$0.0l mg/g to 12.98$\pm$0.03 mg/g, while the PAN increased significantly (P<0.05) from 12.39$\pm$0.10 mg/g (T$_4$) to 14.68$\pm$ 0.30 mg/g (T$_3$). The C : N ratios increased significantly (P<0.0l) from 20.07$\pm$0.20 (T$_3$) to 24.40$\pm$0.10 (T$_3$). The C : ON ratios also increased significantly (P<0.0l) from 28.99$\pm$1.15 (T$_3$) to 35.51$\pm$0.20 (T$_4$). These current research results show increased AN contents and PAN contents in alum treated litter or with increased CP levels regardless of alum treatment. However, none of the litters in this study could initially increase mineralization.

THE COMPUTATION METHOD OF THE MILNOR NUMBER OF HYPERSURFACE SINGULARITIES DEFINED BY AN IRREDUCIBLE WEIERSTRASS POLYNOMIAL $z^n$+a(x,y)z+b(x,y)=0 in $C^3$ AND ITS APPLICATION

  • Kang, Chung-Hyuk
    • Bulletin of the Korean Mathematical Society
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    • v.26 no.2
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    • pp.169-173
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    • 1989
  • Let V={(x,y,z):f=z$^{n}$ -npz+(n-1)q=0 for n .geq. 3} be a compled analytic subvariety of a polydisc in $C^{3}$ where p=p(x,y) and q=q(x,y) are holomorphic near (x,y)=(0,0) and f is an irreducible Weierstrass polynomial in z of multiplicity n. Suppose that V has an isolated singular point at the origin. Recall that the z-discriminant of f is D(f)=c(p$^{n}$ -q$^{n-1}$) for some number c. Suppose that D(f) is square-free. then we prove that by Theorem 2.1 .mu.(p$^{n}$ -q$^{n-1}$)=.mu.(f)-(n-1)+n(n-2)I(p,q)+1 where .mu.(f), .mu. p$^{n}$ -q$^{n-1}$are the corresponding Milnor numbers of f, p$^{n}$ -q$^{n-1}$, respectively and I(p,q) is the intersection number of p and q at the origin. By one of applications suppose that W$_{t}$ ={(x,y,z):g$_{t}$ =z$^{n}$ -np$_{t}$ $^{n-1}$z+(n-1)q$_{t}$ $^{n-1}$=0} is a smooth family of complex analytic varieties near t=0 each of which has an isolated singularity at the origin, satisfying that the z-discriminant of g$_{t}$ , that is, D(g$_{t}$ ) is square-free. If .mu.(g$_{t}$ ) are constant near t=0, then we prove that the family of plane curves, D(g$_{t}$ ) are equisingular and also D(f$_{t}$ ) are equisingular near t=0 where f$_{t}$ =z$^{n}$ -np$_{t}$ z+(n-1)q$_{t}$ =0.}$ =0.

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Effect of Protein Deprivation on Subsequent Efficiency of Dietary Protein Utilization in Finishing Pigs

  • Whang, K.Y.;Donovan, S.M.;Easter, R.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.5
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    • pp.659-665
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    • 2000
  • A nitrogen (N) balance trial was conducted to examine the effect of N deprivation on subsequent N retention, blood urea nitrogen (BUN) and IGF-I levels and the ratio of IGF binding protein (IGFBP)-3 to IGFBP-l and -2. Pigs in treatment (T) 1 were given diet A (2.39% N) and those in T2 and T3 were given diet B (1.31% N) and excreta were collected (period 1 (P1)). Pigs in T1 continued to receive diet A while diets for T2 and T3 were changed to diets A and C (2.74% N), respectively. The excreta were collected for two more periods (P2 and P3). During P1, pigs in T2 and T3 retained 50% less N (p<0.001) than those in T1. However, pigs provided T2 (p<0.01) and T3 (p<0.05) retained more N than those assigned to T1 during P2. Pigs in T3 tended to retain more (p=0.10) N than those receiving T2 for the same period. The BUN values were lower (p<0.05) for pigs assigned to T2 and T3 than T1 during P1 and P2. Both IGF-I and IGFBP ratios of pigs assigned to T1 were higher (p<0.05) than those given T2 and T3 during P1 but no differences were found during P2 and P3.

Effect of Pre-NH3 Stripping on the Advanced Sewerage Treatment by BNR (BNR에 의한 하수의 고도처리에 미치는 NH3 스트리핑 전처리의 영향)

  • Seo, Jeong-Beom;An, Kwang-Ho
    • Journal of Korean Society on Water Environment
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    • v.22 no.5
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    • pp.846-850
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    • 2006
  • The biological nutrient removal from domestic wastewater with low C/N ratio is difficult. Therefore, this study was performed to increase influent C/N ratio by ammonia stripping without required carbon source and for improving treatment efficiencies of sewerage by the combination process of ammonia stripping and BNR (StripBNR). The results of this study were summarized as follows. BOD removal efficiencies of BNR and StripBNR were 95.3% and 93.2%, respectively. T-N and T-P removal efficiencies of BNR were 53.3% and 40.8%, respectively. T-N and T-P removal efficiencies of StripBNR were 72.8% and 62.9%, respectively. Concentrations of $NH_3-N$, $NO_2-N$ and $NO_3-N$ at BNR effluent were 0.03 mg/L, 0.08 mg/L and 9.12 mg/L, respectively. On the other hands, concentrations of $NH_3-N$, $NO_2-N$ and $NO_3-N$ at StripBNR effluent were 5.79 mg/L, 0.01 mg/L and 0.14 mg/L, respectively. Consequently, influent C/N ratio of BNR process was increased by ammonia stripping. Removal efficiency of T-N and T-P was improved about 20% by the process of StripBNR.

Nutrient Removal Characteristics on Organic Material Loadings in Submerged Flat Sheet Type Sequencing Batch Membrane Reactor (침지식 평판형 연속회분식 박반응기에서 유입 유기물 부하의 변화에 따른 영양염류의 제거 특성)

  • Kim, Seung-Geon;Lee, Ho-Won;Kang, Yeung-Joo
    • Membrane Journal
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    • v.20 no.3
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    • pp.241-248
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    • 2010
  • The effect of organic material loadings on nutrient removal characteristics were investigated in sequencing batch reactor, in which a flat sheet type microfiltration membrane with a pore size of $0.4\;{\mu}m$ was submerged. Three organic concentrations of 200 mg/L (Run-1), 400 mg/L (Run-2) and 800 mg/L (Run-3) were carried out continuously to identify their effect on the filtration performance and nutrient removal. The removal efficiencies of T-N and T-P were increased with the increase of COD/N and COD/P. The T-N removal efficiencies of Run-1, Run-2 and Run-3 were 28.1, 32.6 and 90.4%, the average concentrations of T-N in permeate were 32.0, 30.0, and 4.3 mg/L, respectively. The T-P removal efficiencies of Run-1, Run-2 and Run-3 were 13.6, 35.3 and 93.1%, the average concentrations of T-P in permeate were 3.11, 2.33, and 0.25 mg/L, respectively.

Analysis of Water Quality Pollutants Proximated to sediment in Lake (호소내 퇴적물의 근접도에 따른 수질오염물질 분석(I) - COD, T-N, T-P, pH -)

  • Park, Sun-Ku;Yang, Young-Mo
    • Analytical Science and Technology
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    • v.14 no.3
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    • pp.238-243
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    • 2001
  • The study was carried out to analysis of the pollutant $COD_{Mn}$, T-N, T-P for water quality proximated to sediment in lake of K river basin. water extracted from sediment showed higher $COD_{Mn}$, T-N, T-P datas than water proximated to sediment. Also, water proximated to sediment and water 5-10cm proximated to sediment showed the following data : $COD_{Mn}$, 1.2~1.9mg/L, T-N, 1.3~6.2mg/L, TP, 0.05~0.26mg/L, respectively. From this results, we have known the fact that the pollution degree of sediment have an effect on the water quality in lake and stream.

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