• Title/Summary/Keyword: T23

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A Study of the Prognostic Factors in Resected Stage I Non-Small Cell Lung Cancer (제1병기 비소세포폐암 절제례의 예후인자에 대한 연구)

  • 김창수;천수봉;조성래
    • Journal of Chest Surgery
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    • v.31 no.10
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    • pp.973-981
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    • 1998
  • Background: About 30% to 40% of the patients with pathologic stage I non-small cell lung cancer (NSCLC) die within 5 years after complete resection. The identification of poor prognostic factors and the application of additional treatment are very important to improve the survival rate in resected stage I NSCLC. Materials and methods: Sixty-eight(68) patients who had been diagnosed postoperatively between Janury 1989 and December 1995 as having stage I non-small cell lung cancer according to the TNM classification were studied. The postoperative 5-year survival rate was calculated with the Kaplan-Meier method, and clinico- histopathologic factors including age, sex, operative method, type of tumor cell, T factor, grade of the differentiation in a squamous cell carcinoma, invasion of blood vessel and expression of the nm23-H1 protein were investigated and analyzed. Results: The median survival of the entire group of patients was 58$\pm$3 months, with a 5-year survival of 58.9%. In univariate analysis, invasion of blood vessel and poor differentiation of the tumor cell in a squamous cell carcinoma significantly worsened the survival. In multivariate analysis, invasion of blood vessel and grade of the differentiation of the tumor cells in a squamous cell carcinoma remained independent prognostic factors. High expression of the nm23-H1 protein was related to a high postoperative 5-year survival in comparision with low expression of the nm23-H1 pretein (73.0% vs 50.7%), but there was no statistical significance. Conclusions: These results highlight the negative prognostic value of poor differentiation of tumor cells in a squamous cell carcinoma and invasion of blood vessel in stage I non-small cell lung cancer. Also, further studies are necessary to be determined prognostic value of the T factor and expression of the nm23 protein in non-small cell lung cancer.

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IoT Roaming Service for Seamless IoT Service (무중단 IoT 서비스 제공을 위한 IoT 로밍서비스)

  • Ahn, Junguk;Lee, Byung Mun
    • Journal of Korea Multimedia Society
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    • v.23 no.10
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    • pp.1258-1269
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    • 2020
  • The IoT(Internet of Things) service provides users with valuable services by collecting and analyzing data using Internet-connected IoT devices. Currently, IoT service platforms are accomplished by using edge computing to reduce the delay time required to collect data from IoT devices. However, if a user moves to another network with IoT device, the connection will be lost and IoT service will be suspended. To solve this problem, we proposes a service that automatically roaming IoT service when IoT device makes move. IoT roaming service provides a device automatic tracking management technique designed to continue receiving IoT services even if users move to other networks. To check if the proposed roaming service was effective, we implemented IoT roaming service and measured the data transfer time while move between networks along with devices while using IoT service. As a result, the average data transfer time was 124.62ms, and the average service interrupt time was 812.12ms. with this result, we can assume that the user could feel service interruption time very shortly and it will not affect the service experience. with IoT roaming service, we expect that it will present a method that stably providing IoT services even if user moves networks.

UNIFORMLY LIPSCHITZ STABILITY AND ASYMPTOTIC PROPERTY IN PERTURBED NONLINEAR DIFFERENTIAL SYSTEMS

  • CHOI, SANG IL;GOO, YOON HOE
    • The Pure and Applied Mathematics
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    • v.23 no.1
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    • pp.1-12
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    • 2016
  • This paper shows that the solutions to the perturbed differential system $y^{\prime}=f(t, y)+\int_{to}^{t}g(s,y(s),Ty(s))ds+h(t,y(t))$ have asymptotic property and uniform Lipschitz stability. To show these properties, we impose conditions on the perturbed part $\int_{to}^{t}g(s,y(s),Ty(s))ds+h(t,y(t))$, and on the fundamental matrix of the unperturbed system y' = f(t, y).

Understanding the Internet of Things: Education and Experience

  • Yun, Jaeseok
    • Journal of the Korea Society of Computer and Information
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    • v.23 no.12
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    • pp.137-144
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    • 2018
  • In this paper, we propose an well-organized lecture note for giving a better understanding on the Internet of Things (IoT) to people including non-computer majors without computing and communication knowledge. In recent years, the term 'IoT' has been popularized, and IoT will make a huge impact on our industries, societies, and environments. Although there are large amount of literature on presenting IoT from technological perspectives, few are published that are organized for teaching students having non-computer-related majors. Based on research and education experiences on IoT, we tried to make a lecture note focusing on the process of collecting data from everyday objects, transmitting and sharing data, and utilizing data to create new values for us. The proposed lecture note was employed in teaching a liberal arts class, and it was shown that students could have an understanding of what IoT really means and how IoT could change our world.

Ontology Based-Security Issues for Internet of Thing (IoT): Ontology Development

  • Amir Mohamed Talib
    • International Journal of Computer Science & Network Security
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    • v.23 no.8
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    • pp.168-176
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    • 2023
  • The use of sensors and actuators as a form of controlling cyber-physical systems in resource networks has been integrated and referred to as the Internet of Things (IoT). However, the connectivity of many stand-alone IoT systems through the Internet introduces numerous security challenges as sensitive information is prone to be exposed to malicious users. In this paper, IoT based-security issues ontology is proposed to collect, examine, analyze, prepare, acquire and preserve evidence of IoT security issues challenges. Ontology development has consists three main steps, 1) domain, purpose and scope setting, 2) important terms acquisition, classes and class hierarchy conceptualization and 3) instances creation. Ontology congruent to this paper is method that will help to better understanding and defining terms of IoT based-security issue ontology. Our proposed IoT based-security issue ontology resulting from the protégé has a total of 44 classes and 43 subclasses.

Use of Blockchain to Support the Security of Internet of Things: A Review

  • Saher Un Nisa;Maryam Khalid
    • International Journal of Computer Science & Network Security
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    • v.23 no.7
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    • pp.149-154
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    • 2023
  • Internet of Things (IoT) is now spreading everywhere. It's the technology of every person's need so we can't step back from IoT but we can secure it as it is spreading quickly so it has greater chances of danger and being misused. There is an urgent need to make IoT devices secure from getting cracked or hacked. A lot of methods had tried and still trying to mitigate IoT security issues. In this paper Blockchain is going to be the solution of most of the IoT issues or problems. We have discussed or highlighted security issues with centralized IoT and then provided solution of such security challenges through the use of blockchain because is based on a decentralized technology that is hard to modify or update.

Roles of Virtual Memory T Cells in Diseases

  • Joon Seok;Sung-Dong Cho;Seong Jun Seo;Su-Hyung Park
    • IMMUNE NETWORK
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    • v.23 no.1
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    • pp.11.1-11.11
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    • 2023
  • Memory T cells that mediate fast and effective protection against reinfections are usually generated upon recognition on foreign Ags. However, a "memory-like" T-cell population, termed virtual memory T (TVM) cells that acquire a memory phenotype in the absence of foreign Ag, has been reported. Although, like innate cells, TVM cells reportedly play a role in first-line defense to bacterial or viral infections, their protective or pathological roles in immune-related diseases are largely unknown. In this review, we discuss the current understanding of TVM cells, focusing on their distinct characteristics, immunological properties, and roles in various immune-related diseases, such as infections and cancers.

Analysis of 16S-23S rRNA Intergenic Spacer Regions of Aeromonas veronii biogroup sobria and A. caviae (Aeromonas veronii biogroup sobria와 Aeromonas caviae의 16S-23S rRNA Intergenic Spacer Regions 분석)

  • 강동율;이훈구
    • Korean Journal of Microbiology
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    • v.36 no.3
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    • pp.173-180
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    • 2000
  • The intern1 spacer regions (ISR) between the 16s and 23s $1_RNA$ genes of Aeronzonus iwonii blogroupsobria and A. caviae were investigated by PCR fragment length typing and DNA sequencing. A. iwonii bv.sobria has a speciIic 16s-23s pattern of 2-4 fiagments ranging Goin 479-539 bp, with the exception of thespecies Aeron7onns cmiae, which has 3 fragments ranglog from 470-602 bp. In all of the.4 vei*onii bv. sobr,iaand A, caviae strains examined in this study, the 470-481bp Tragnent, designated TSR-1, invariably contained $tDNA^{uc(GAT)$ and $tDNA^{Ala(TGC)$ in contrast to ISR-2 (513-525 bp). ISR-3 (537-539 bp) and ISR-4 (568-602 bp)containing TEX>$tDNA^{Olu(ITC)$ A stretch of 20 nucleotides (178-197 bp) in the ISR-4 was conserved only wit11mA.caiiue, from which the A. caiiae specific primer, named prAC-F, was designed and used for PCR with aAcaviae coimnon reverse primer A PCR product of 450 bp was apparent alnong I , caiizne strains, but not ii1.4.ijeronii bv. sob~ia strains. The PCR product was oot detected t"-om strains belonging to A. hjili-o~~hila, Ebrio,aud the family Ef\ulcornertei,obncteriaceae. This study provides the first molecular tool for mdentifying the species 8.caviae.ing the species 8. caviae.

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