• Korean Journal of Mathematics
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• v.23 no.2
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• pp.269-282
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• 2015

In this paper, we investigate bounds for solutions of perturbed functional differential systems using the notion of $t_{\infty}$-similarity.

• Journal of the Korean Chemical Society
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• v.46 no.2
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• pp.157-163
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• 2002

To identify RNA motifs interacting with $tRNA^{Val}$, a SELEX(Systematic Evolution of Ligands by Exponential Enrichment) was applied. Random DNA library which contains a region of ran-domized 48-mer oligonucleotide flanked by conserved sequ ence primers was transcribed into RNA pool using T7 RNA polymerase and RNA aptamers were selected with $tRNA^{Val}$ -immobilized affinity column through 14 rounds of SELEX. Some of the resulting aptamers contained a consensus sequence similar to the sequence in the loop regions of three rRNAs; C43GAAC47 sequence of 5S rRNA, G1491AAGU1495, G1379UUCC1383 sequence of 16S rRNA and C1064UUAG1068, G2110UGUA2114, C2480GACGG2485, A2600CAGU2604 sequence of 23S rRNA. These results suggest that $tRNA^{Val}$ can interact with 5S rRNA, 16S rRNA and 23S rRNA with variety in ribosome.

• Journal of the Chungcheong Mathematical Society
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• v.23 no.4
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• pp.757-771
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• 2010

We study Gauss sums on ${\mathbb{F}}_q[T]$ and get some functional equations for L-functions.

• IMMUNE NETWORK
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• v.23 no.5
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• pp.41.1-41.21
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• 2023

CD4 and CD8 T cells are key players in the immune response against both pathogenic infections and cancer. CD4 T cells provide help to CD8 T cells via multiple mechanisms, including licensing dendritic cells (DCs), co-stimulation, and cytokine production. During acute infection and vaccination, CD4 T cell help is important for the development of CD8 T cell memory. However, during chronic viral infection and cancer, CD4 helper T cells are critical for the sustained effector CD8 T cell response, through a variety of mechanisms. In this review, we focus on T cell responses in conditions of chronic Ag stimulation, such as chronic viral infection and cancer. In particular, we address the significant role of CD4 T cell help in promoting effector CD8 T cell responses, emerging techniques that can be utilized to further our understanding of how these interactions may take place in the context of tertiary lymphoid structures, and how this key information can be harnessed for therapeutic utility against cancer.

• Parasites, Hosts and Diseases
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• v.31 no.3
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• pp.231-238
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• 1993

Effects of Paragonims westermai infection were observed in mice on the change of serum IgE level, the number of peripheral eosinophils and the distribution of Thy $1.2^{+}{\;}(CD3),{\;}L3T4^{+}{\;}(CD4),{\;}and{\;}Lyt-2^{+}$ (CD8) splenic T Iymphocytes without mitogen serum IgE increased at 3 weeks after the infection and reached a peak on week 4 and maintained high levels of IgE until the 23r6 week. Peripheral eosinophil numbers Increased at the second week and attained peak level on week 9. The frequency of $L3T4^{+}$(CD4) and $Lyt-2^{+}$ (CD8) T Iymphocytes decreased slightly until 4 weeks after the infection, but not significantly. Absolute number of $L3T4^{+}{\;}and{\;}Lyt-2^{+}$ T Iymphocytes, and the ratio of L3T4/Lyt-2 were not markedly changed over the period of observation. The frequency of Thy $1.2^{+}$ (CD3) T lymphocytes in the infected group slightly decreased until 4 weeks after the infection and showed significant reductions at the 2nd and 4th week of the infection (p < 0.05).

• Communications for Statistical Applications and Methods
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• v.23 no.4
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• pp.321-334
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• 2016

In this paper, we propose power t distribution based on t distribution. We also study the properties of and inferences for power t model in order to solve the problem of real data showing both skewness and heavy tails. The comparison of skew t and power t distributions is based on density plots, skewness and kurtosis. Note that, at the given degree of freedom, the kurtosis's range of the power t model surpasses that of the skew t model at all times. We draw inferences for two parameters of the power t distribution and four parameters of the location-scale extension of power t distribution via maximum likelihood. The Fisher information matrix derived is nonsingular on the whole parametric space; in addition we obtain the profile log-likelihood functions on two parameters. The response plots for different sample sizes provide strong evidence for the estimators' existence and unicity. An application of the power t distribution suggests that the model can be very useful for real data.

• Journal of Environmental Impact Assessment
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• v.21 no.5
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• pp.745-755
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• 2012

The relations between tributaries and mainstream were identified with the water qualities measurements in the field. Parameters of water qualities were BOD, T-N, T-P and measurements were performed by 4 events of rainfalls for 2011. The precipitation data influenced on pollutants loads. Pollutants loads were fluctuations with the seasonal variation. Gajoacheon contributed in 18.39% of BOD, 23.79% of T-N, 15.23% of T-P and Nabulcheon contributed in 13.54% of BOD, 13.05% of T-N and 13.66% of T-P in the region from Nam River_C to Nam River_D. In case of the region from Nam River_C to Nam River_D, Yongacheon river inflowed to main stream as 23.65% of BOD, 20.74% of T-N, and 15.05% of T-P.

• Korean Journal of Mathematics
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• v.23 no.4
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• pp.601-605
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• 2015

In the present note, provided $T{\in}{\mathfrak{L}}({\mathfrak{H}})$ is biquasitriangular and Browder's theorem hold for T, we show that the spectrum ${\sigma}$ is continuous at T if and only if the essential spectrum ${\sigma}_e$ is continuous at T.

• Journal of the Chungcheong Mathematical Society
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• v.23 no.3
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• pp.443-452
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• 2010

This work deals with the existence of uncountably many bounded positive solutions for the third order nonlinear neutral delay differential equation $$\frac{d^3}{dt^3}[x(t)+p(t)x(t-{\tau})]+f(t,x(t-{{\tau}_1}),{\ldots},x(t-{{\tau}_k}))=0,\;t{\geq}t_0$$ where ${\tau}>0$, ${\tau}_i{\in}{\mathbb{R}^+}$ for $i{\in}\{1,2,{\ldots},k\}$, $p{\in}C([t_0,+{\infty}),{\mathbb{R}^+})$ and $f{\in}C([t_0,+{\infty}){\times}{\mathbb{R}^k},{\mathbb{R}})$.

• Korean Journal of Environmental Biology
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• v.21 no.1
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• pp.77-85
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• 2003

We have examined the 16S-23S rRNA intergenic spacer regions (ISR) of Vibrio fluvialis. ISRs were PCR amplified, cloned into a plasmid vector and then sequenced. As results of ISR nucleotide sequence analysis, total of 6 clones were isolated depending on the size. The clones were different in both the number and the composition of the tRNA genes, and were designated ISR-A, ISR-E, ISR-El, ISR-lA, ISR-EKV, ISR-EKAV. ISR-A contains $tRNA^{Ala}$; ISR-lA, $tRNA^{Ile}$-$tRNA^{Ala}$; ISR-EKV, $tRNA^{GIu}$-$tRNA^{Lys}$-$tRNA^{Val}$;ISE-EKAV, $tRNA^{GIu}$-$tRNA^{Lys}$-$tRNA^{Ala}$-$tRNA^{Val}$; ISR -E and E1, $tRNA^{GIu}$ clusters. ISR-EKV was shown to be a minor type out of the six ISR types and showed a very limited homology between ISR-EKV from V, fluvialis and ISRa from other Vibrio species. Therefore ISR-EKV sequence was used to design species-specific primers to detect V, fiuvialis from other Vibrio species by PCR reaction. The specificity of the primers was examined using genomic DNA of other Vibrios as templates for PCR reaction. The result showed that PCR can be a useful method to detect V. fluvialis among Vibrio species in a single PCR reaction.