• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.7337-7342
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• 2015

The study aimed to investigate the profile of alkaloids in two ethyl acetate soluble fractions, namely fractions A and B from an ethanolic extract of Ficus septica leaves and cytotoxic effect on T47D breast cancer cells. Preparation of both fractions involved maceration of leaves with 70% (v/v) ethanol, filtration with $Al_2O_3$, precipitation with 0.1 N HCl, Mayer reagent, and 0.1 N NaOH, and also partition with ethyl acetate. Qualitative thin layer chromatography (TLC) was conducted to determine the profile of alkaloids in the two fractions, using alkaloid specific reagents such as Dragendorff, sodium nitrite, and Van Urk-Salkowski. Cytotoxic effects of both fractions on T47D cells were evaluated using MTT assay with a concentration series of 1.56; 3.12; 6.25; 12.5; 25 and $50{\mu}g/mL$. The TLC test showed that fractions A and B contained alkaloids with Rx values of 0.74 and 0.80 for fraction A and 0.74, 0.84, 0.92 for fraction B with regard to yohimbine using the mobile phase of n-buthanol:glacial acetic acid:distilled water (3:1:1 v/v/v). Moreover, an indole alkaloid was detected with Rx values of 0.80 and 0.84, respectively. Fractions A and B exhibited high cytotoxic effects on T47D cells with IC50 values of 2.57 and $2.73{\mu}g/mL$, respectively. In conclusion, overall the results of this study showed that fractions of Ficus septica contain alkaloids including indole alkaloid or its derivatives and possess a cytotoxic effect on T47D cells. This research supports the idea that alkaloids in F. septica have anticancer activity.

• Steel and Composite Structures
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• 제16권1호
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• pp.97-114
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• 2014

This paper deals with a study on ultimate strength behaviour of eccentrically loaded CFT columns with and without shear connectors. Thirty specimens are subjected to experimental investigation under eccentric loading condition. P-M curves are generated for all the test specimens and critical eccentricities are evaluated. Three different D/t ratios such as 21, 25 and 29 and L/D ratios varying from 5 to 20 are considered as experimental parameters. Six specimens of bare steel tubes as reference specimens, twelve specimens of CFT columns without shear connectors and twelve specimens of CFT columns with shear connectors, in total thirty specimens are tested. The P-M values at the ultimate failure load of experimental study are found to be well agreed with the results of the proposed P-M interaction model. The load-deflection and load-strain behaviour of the experimental column specimens are presented. The behaviour of the CFT columns with and without shear connectors is compared. Experimental results indicate that the percentage increase in load carrying capacity of CFT columns with shear connectors compared to the ordinary CFT columns is found to be insignificant with a value ranging from 6% to 13%. However, the ductility factor of columns with shear connectors exhibit higher values than that of the CFT columns without shear connectors. This paper presents the proposed P-M interaction model and experimental results under varying parameters such as D/t and L/D ratios.

• 전기전자학회논문지
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• 제20권3호
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• pp.318-321
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• 2016

IoT 산업이 빠르게 성장하면서 전원 관리 집적회로의 중요성이 부각되고 있다. 본 논문에서는 리플 Subtractor, 피드 포워드 커패시터, OTA를 이용한 LDO 구조를 제안한다. 이를 통해 10MHz가 넘는 고주파 영역에서도 -40dB 이상 높은 전원 전압 제거비(PSRR)를 얻었다. 설계된 Low-Dropout(LDO) 레귤레이터는 $0.18{\mu}m$ CMOS 공정에서 설계되었으며 시뮬레이션 결과 PSRR은 부하 전류 40mA, 500kHz에서 -73.4dB다. 최대 구동 가능 전류는 40mA이다.

• 대한소아치과학회지
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• 제8권1호
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• pp.89-102
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• 1981

1147 preschool children aged from 3 to 6 living in some farm villages in Kyungki-do were surveyed on dmf and distribution of dental caries in primary dentition. The results were as follows: 1. dmf rate ... 92.76 % boy ... 94.52 % girl ... 90.5.5 % 2. dmf t rate ... 37.07 % dmf t index ... 7.09 3. dmf s rate ... 13.74 % dmf s index ... 13.14 % 4. df t index ... 6.94 5. Each percentage of d, m & f per dmf teeth d rate ... 89.96 % m rate ... 7.24 % f rate ... 2.67 % 6. Most frequent site of dental caries in each tooth $\underline{A}$ mesial $\overline{A}$ distal $\underline{B}$ mesial $\overline{B}$ distal $\underline{C}$ distal $\overline{C}$ distal $\underline{D}$ disto-occlusal $\overline{D}$ disto-occlusal $\underline{E}$ linguo-occlusal $\overline{E}$ occlusal 7. Order of caries susceptibility $\overline{E}$ $\underline{E}$ $\overline{D}$ $\underline{D}$ $\underline{A}$ $\underline{B}$ $\overline{C}$ $\underline{C}$ $\overline{B}$ $\overline{A}$ 8. All the values in caries criteria showed a marked increae from those of 1968.

• 생물환경조절학회지
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• 제16권3호
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• pp.199-204
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• 2007

배양액 농도가 호접란 미니다화성계 품종 P. amabilis와 P. Taisuco Red Jewel의 유묘와 중간묘의 생장에 미치는 영향을 알아보기 위해 ebb and low system을 이용하여 4개월 재배한 결과는 다음과 같다. 유묘의 경우 엽장과 엽폭이 P. amabilis는 배양액의 EC가 $0.5{\sim}1.0dS{\cdot}m^{-1}$일 때 가장 길었으나 P. Taisuco Red Jewel 배양액의 EC가 $1.5dS{\cdot}m^{-1}$일 때 가장 길었다. 반면에 근장과 근중은 두 품종 모두 배양액의 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 무거웠고 이러한 경향은 중간묘에서도 동일하게 나타났다. 잎의 생체중과 건물중은 P. amabilis의 경우 배양액의 EC가 $1.5dS{\cdot}m^{-1}$로 높을 때 가장 무거웠으며, 배양액의 EC가 낮아질수록 잎의 생체중과 건물중은 낮아졌다. 반대로 뿌리의 생체중은 배양액 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 무거웠고, 배양액의 EC가 높아질수록 가벼워졌으며, P. Taisuco Red Jewel에서도 같은 경향이었다. 중간묘의 경우 뿌리의 생체중과 건물중이 P. amabilis는 배양액 EC가 $0.5dS{\cdot}m^{-1}$로 낮을 때 가장 높았고, 배양액의 EC가 높아질수록 뿌리의 생체중은 낮아졌다. T/R율과 잎의 엽록소함량은 유묘와 마찬가지로 두 품종 모두 배양액의 EC가 $1.5dS{\cdot}m^{-1}$로 높을 때 가장 높았으며, 배양액의 농도가 낮아질수록 낮아졌다.

• 한국수학교육학회지시리즈A:수학교육
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• 제29권1호
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• pp.41-45
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• 1990

S. Z. Wang, B. Y. Li, Z. M. Gao and K. Iseki proved some fixed point theorems on expansion mappings, which correspond some contractive mappings. In a recent paper, B. E. Rhoades generalized the results for in of mappings. In this paper, we obtain the following theorem, which generalizes the result of B. E. Rhoades. THEOREM. Let A, B, S and T be mappings from a complete metric space (X, d) into itself satisfying the following conditions: (1) ${\Phi}$(d(A$\chi$, By))$\geq$d(Sx, Ty) holds for all x and y in X, where ${\Phi}$ : R$\^$+/ \longrightarrowR$\^$+/ is non-decreasing, uppersemicontinuous and ${\Phi}$(t) < t for each t > 0, (2) A and B are surjective, (3) one of A, B, S and T is continuous, and (4) the pairs A, S and B, T are compatible. Then A, B, S and T have a unique common fixed point in X.

• 정보관리학회지
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• 제6권1호
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• pp.15-36
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• 1989

마이크로 컴퓨터의 급속한 성장에 따라 그 이용 범위 또한 넓어지게 되었다. 본고에 서는 이러한 마이크로 컴퓨터를 이용해 원자력 정책 자료 검색 시스템을 설계하였다.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2007년도 The 1st International Symposium on Advanced Magnetic Materials
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• pp.92.1-92.1
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• 2007

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2003년도 High Temperature Superconductivity Vol.XIII
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• pp.30-30
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• 2003

• 대한약학회:학술대회논문집
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• 대한약학회 2000년도 춘계총회 및 학술대회
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• pp.193.1-193.1
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• 2000