• Title/Summary/Keyword: T-junction

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Flow Analysis of POSRV Subsystem of Standard Korean Nuclear Reactor (한국 표준형 원전의 POSRV 하부 배관 유동해석)

  • Kwon, Soon-Bum;Kim, In-Goo;Ahn, Hyung-Joon;Lee, Dong-Eum;Baek, Seung-Cheol;Lee, Byeong-Eun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.27 no.10
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    • pp.1464-1471
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    • 2003
  • In order to investigate the flows with shock wave in branch, 108$^{\circ}$ elbow and T-junction of the IRWST system of standard Korean nuclear reactor, detail time dependent behaviors of unsteady flow with shock wave, vortex and so on are obtained by numerical method using compressible three-dimensional Navier-Stokes equations. At first, the complex flow including the incident and reflected shock waves, vortex and expansion waves which are generated at the corner of T-junction is calculated by the commercial code of FLUENT6 and is compared with the experimental result to obtain the validation of numerical method. Then the flow fields in above mentioned units are analyzed by numerical method of [mite volume method. In numerical analysis, the distributions of flow properties with the moving of shock wave and the forces acting on the wall of each unit which can be used to calculate the size of supporting structure in future are calculated specially. It is found that the initial shock wave of normal type is re-established its type from an oblique one having the same strength of the initial shock wave at the 4 times hydraulic diameters of downstream from the branch point of each unit. Finally, it is turned out that the maximum force acting on the pipe wall becomes in order of the T-junction, 108$^{\circ}$ elbow and branch in magnitude, respectively.

Lipoteichoic Acid Isolated from Staphylococcus aureus Induces Both Epithelial-Mesenchymal Transition and Wound Healing in HaCaT Cells

  • Kim, Seongjae;Kim, Hyeoung-Eun;Kang, Boyeon;Lee, Youn-Woo;Kim, Hangeun;Chung, Dae Kyun
    • Journal of Microbiology and Biotechnology
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    • v.27 no.10
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    • pp.1820-1826
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    • 2017
  • Lipoteichoic acid (LTA), a cell wall component of gram-positive bacteria, is recognized by Toll-like receptor 2, expressed on certain mammalian cell surfaces, initiating signaling cascades that include nuclear factor kappa-light-chain-enhancer of activated B cells (NF-${\kappa}B$) and mitogen-activated protein kinase. There are many structural and functional varieties of LTA, which vary according to the different species of gram-positive bacteria that produce them. In this study, we examined whether LTA isolated from Staphylococcus aureus (aLTA) affects the expression of junction proteins in keratinocytes. In HaCaT cells, tight junction-related gene expression was not affected by aLTA, whereas adherens junction-related gene expression was modified. High doses of aLTA induced the phosphorylation of extracellular signal-regulated protein kinases 1 and 2, which in turn induced the epithelial-mesenchymal transition (EMT) of HaCaT cells. When cells were given a low dose of aLTA, however, NF-${\kappa}B$ was activated and the total cell population increased. Taken together, our study suggests that LTA from S. aureus infections in the skin may contribute both to the outbreak of EMT-mediated carcinogenesis and to the genesis of wound healing in a dose-dependent manner.

Liquid entrainment through a large-scale inclined branch pipe on a horizontal main pipe

  • Gu, Ningxin;Shen, Geyu;Lu, Zhiyuan;Yang, Yuenan;Meng, Zhaoming;Ding, Ming
    • Nuclear Engineering and Technology
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    • v.52 no.6
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    • pp.1164-1171
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    • 2020
  • T-junction structures play an important role in nuclear power plant systems. Research on liquid entrainment is mostly based on small-scale branch pipes (d/D ≤ 0.2) and attention paid to large-scale branch pipes (0.33 < d/D < 1) is insufficient. Accordingly, this study implements a series of experiments on the liquid entrainment of T-junction with different angles (32.2°,47.9°,62.3°,90°) through a large-scale branch (d/D = 0.675). The onset liquid entrainment is related to the gas phase Froude number Frg, the dimensionless gas chamber height hb/d and the branch pipe angle 𝜃. As Frg increases, hb/d also rises. With a constant hb/d, the onset liquid entrainment changes from droplets entrainment by the gas phase to that by the rising liquid film. The steady-state liquid entrainment is related to w3g, h/d and 𝜃. With constant w3g and h/d, the branch quality grows as the branch angle increases. With a certain h/d, the branch quality increases, as the w3g number increases.

CHAINED COMPUTATIONS USING AN UNSTEADY 3D APPROACH FOR THE DETERMINATION OF THERMAL FATIGUE IN A T-JUNCTION OF A PWR NUCLEAR PLANT

  • Pasutto, Thomas;PENiguel, Christophe;Sakiz, Marc
    • Nuclear Engineering and Technology
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    • v.38 no.2
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    • pp.147-154
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    • 2006
  • Thermal fatigue of the coolant circuits of PWR plants is a major issue for nuclear safety. The problem is especially accute in mixing zones, like T-junctions, where large differences in water temperature between the two inlets and high levels of turbulence can lead to large temperature fluctuations at the wall. Until recently, studies on the matter had been tackled at EDF using steady methods: the fluid flow was solved with a CFD code using an averaged turbulence model, which led to the knowledge of the mean temperature and temperature variance at each point of the wall. But, being based on averaged quantities, this method could not reproduce the unsteady and 3D effects of the problem, like phase lag in temperature oscillations between two points, which can generate important stresses. Benefiting from advances in computer power and turbulence modelling, a new methodology is now applied, that allows to take these effects into account. The CFD tool Code_Saturne, developped at EDF, is used to solve the fluid flow using an unsteady L.E.S. approach. It is coupled with the thermal code Syrthes, which propagates the temperature fluctuations into the wall thickness. The instantaneous temperature field inside the wall can then be extracted and used for structure mechanics computations (mainly with EDF thermomechanics tool Code_Aster). The purpose of this paper is to present the application of this methodology to the simulation of a straight T-junction mock-up, similar to the Residual Heat Remover (RHR) junction found in N4 type PWR nuclear plants, and designed to study thermal striping and cracks propagation. The results are generally in good agreement with the measurements; yet, in certain areas of the flow, progress is still needed in L.E.S. modelling and in the treatment of instantaneous heat transfer at the wall.

YBa$_2$Cu$_3$O$_{7-{\delta}}$/SrTiO$_3$/YBa$_2$Cu$_3$O$_{7-{\delta}}$ multilayer structures for ground planes for ramp-edge junction devices

  • Kim, C.H.;Kim, Y.H.;Jung, K.R.;Hahn, T.S.;Park, J.H.;Choi, S.S.
    • 한국초전도학회:학술대회논문집
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    • v.10
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    • pp.179-183
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    • 2000
  • For a ground plane in high-temperature superconducting ramp-edge junction devices, YBa$_2$Cu$_3$O$_{7-{\delta}}$/SrTiO$_3$/YBa$_2$Cu$_3$O$_{7-{\delta}}$ multilayer structures were fabricated using pulsed laser deposition and ECR ion milling. Various process parameters were adjusted to enhance the device characteristics. By etching the STO layer to form a tapered edge of about 15$^{\circ}$ and in-situ RF plasma treatment of bottom YBCO surface prior to deposition of top YBCO, the top-to-bottom YBCO showed T$_c$ of 75${\sim}$80 K and I$_c$ of about 40 mA through holes. It was found that the deposition of bottom YBCO at a reduced laser repetition rate of 1Hz increased the T$_c$ of top YBCO to 79.9 K. The resistivity of 570 layer was about 10$^6$ ${\Omega}$cm at 60 K, which ensures good electrical isolation between successive YBCO layers.

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Electrical Characteristics of Ti Self-Aligned Silicide Contact (Ti Self-Aligned Silicide를 이용한 Contact에서의 전기적 특성)

  • 이철진;허윤종;성영권
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.2
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    • pp.170-177
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    • 1992
  • Contact resistance and contact leakage current of the Al/TiSiS12T/Si system are investigated for NS0+T and PS0+T junctions. SALICIDE (Self Aligned Silicide) process was used to make the Al/TiSiS12T/Si system. Titanium disilicide is one of the most common silicides because of its thermal stability, ability to form selective formation and low resistivity. In this paper, RTA temperature effect and Junction implant dose effect were evaluated to characterize contact resistance and contact leakage current. The TiSiS12T contact resistance to NS0+T silicon is lower than that to PS0+T silicon, and TiSiS12T of contact leakage current to NS0+T silicon is lower than that to PS0+T silicon. Contact resistance and contact leakage current of the Al/TiSiS12T/Si system by this method were possible for VLSI application.

Multiplex PCR Detection of the GT73, MS8xRF3, and T45 Varieties of GM Canola

  • Kim, Jae-Hwan;Kim, Tae-Woon;Lee, Woo-Young;Park, Sun-Hee;Kim, Hae-Yeong
    • Food Science and Biotechnology
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    • v.16 no.1
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    • pp.104-109
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    • 2007
  • A multiplex polymerase chain reaction (PCR) method was developed to simultaneously detect three varieties of genetically modified (GM) canola. The construct-specific primers were used to distinguish the following three varieties of GM canola; GT73, MS8xRF3, and T45, using multiplex PCR. The FatA (fatty acyl-ACP thioesterase) gene was used as an endogenous canola reference gene in the PCR detection. The primer pair Canendo-FIR containing a 105 bp amplicon was used to amplify the FatA gene and no amplified product was observed in any of the 15 different plants used as templates. The GT73-KHUF1/R1 primer recognized the 3'-flanking region of GT73, resulting in an amplicon of 125 bp. The Barstar-F1/MS8xRF3-R primer recognized the junction region of bars tar and the NOS terminator introduced into MS8xRF3, resulting in a 162 bp amplicon, and the T45-F2/R2 primer recognized the junction region of PAT and the 35S terminator introduced into T45, resulting in an amplicon of 186 bp. This multiplex PCR allowed for the detection of construct-specific targets in a genomic DNA mixture of up to 1% GM canola containing GT73, MS8xRF3, and T45.

Analysis of the Risk Factors for Unfavorable Radiologic Outcomes after Fusion Surgery in Thoracolumbar Burst Fracture : What Amount of Postoperative Thoracolumbar Kyphosis Correction is Reasonable?

  • Seo, Dong Kwang;Kim, Chung Hwan;Jung, Sang Ku;Kim, Moon Kyu;Choi, Soo Jung;Park, Jin Hoon
    • Journal of Korean Neurosurgical Society
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    • v.62 no.1
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    • pp.96-105
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    • 2019
  • Objective : The aims in the management of thoracolumbar spinal fractures are not only to restore vertebral column stability, but also to obtain acceptable alignment of the thoracolumbar junction (T-L junction) to prevent complications. However, insufficient surgical correction of the thoracolumbar spine would be likely to cause late progression of abnormal kyphosis. Therefore, we identified the surgical factors that affected unfavorable radiologic outcomes of the thoracolumbar spine after surgery. Methods : This study was conducted in a single institution from January 2007 to December 2013. A total of 98 patients with unstable thoracolumbar spine fracture were included. In these patients, fixation was done through transpedicular screws with rods by three surgical patterns. We reviewed digital radiographs and analyzed the images preoperatively and postoperatively during follow-up visits to compare the change of the thoracolumbar Cobb angle with radiologic parameters and clinical outcomes. The unfavorable radiologic group was defined as the patients who were measured as having greater than 20 degrees of thoracolumbar Cobb angle on the last follow-up, or who underwent kyphotic progression of thoracolumbar Cobb angle greater than 10 degrees from the immediate postoperative state to final follow-up, or who had overt instrument failure with/without additional surgery. We assessed the risk factors that affected the unfavorable radiologic outcomes. Results : We had 43 patients with unfavorable radiologic outcomes, including 35 abnormal thoracolumbar alignments and 14 instrumental failures with/without additional surgery. The multivariate logistic regression test showed that immediate postoperative T-L junction Cobb angle less than 10.5 degrees was a statistically significant risk factor, as well as the presence of osteoporosis (p=0.017 and 0.049, respectively). Conclusion : Insufficient correction of thoracolumbar kyphosis was considered to be a major factor of an unfavorable radiological outcome. The spinal surgeon should consider that having a T-L junction Cobb angle larger than 10.5 degrees immediately after surgery could result in an unfavorable radiological outcome, which is related to a poor clinical outcome.