• Journal for History of Mathematics
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• v.20 no.3
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• pp.127-146
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• 2007

From 1876 to 1883, British mathematician James Joseph Sylvester worked as the founding head of Mathematics Department at the Johns Hopkins University which has been known as America's first school of mathematical research. Sylvester established the American Journal of Mathematics, the first sustained mathematics research journal in the United States. It is natural that we think this is the most exciting and important period in American mathematics. But we found out that the International Congress of Mathematicians held at the World's Columbian Exposition in Chicago, August 21-26, 1893 was the real turning point in American's dedication to mathematical research. The University of Chicago was founded in 1890 by the American Baptist Education Society and John D. Rockefeller. The founding head of mathematics department Eliakim Hastings Moore was the one who produced many excellent American mathematics Ph.D's in early stage. Many of Moore's students contributed to build up real American mathematics research power in early 20 century The University also has a well-deserved reputation as the "teacher of teachers". Beginning with Sylvester, we analyze what E.H. Moore had done as a teacher and a head of the new department that produced many mathematical talents such as L.E. Dickson(1896), H. Slaught(1898), O. Veblen(1903), R.L. Moore(1905), G.D. Birkhoff(1907), T.H. Hilderbrants(1910), E.W. Chittenden(1912) who made the history of American mathematics. In this article, we study how Moore's vision, new system and new way of teaching influenced American mathematical society at early stage of the top class mathematical research. and the meaning that early University of Chicago case gave.

• Archives of Plastic Surgery
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• v.42 no.2
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• pp.207-213
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• 2015

Background Pincer nail deformity is a transverse overcurvature of the nail. This study aimed to define the anatomical characteristics of pincer nail deformity and to evaluate the surgical outcomes. Methods A retrospective review was conducted on 20 cases of pincer nail deformity of the great toe. Thirty subjects without pincer nail deformity or history of trauma of the feet were selected as the control group. Width and height indices were calculated, and interphalangeal angles and base widths of the distal phalanx were measured with radiography. We chose the surgical treatment methods considering perfusion-related factors such as age, diabetes mellitus, kidney disease, and peripheral vascular disease. The zigzag nail bed flap method (n=9) and the inverted T incision method (n=11) were used to repair deformities. The outcomes were evaluated 6 months after surgery. Results The interphalangeal angle was significantly greater in the preoperative patient group ($14.0^{\circ}{\pm}3.6^{\circ}$) than in the control group ($7.9^{\circ}{\pm}3.0^{\circ}$) (P<0.05). The postoperative width and height indices were very close to the measurements in the control group, and most patients were satisfied with the outcomes. Conclusions We believe that the width and height indices are useful for evaluating the deformity and outcomes of surgical treatments. We used two different surgical methods for the two patient groups with respect to the perfusion-related factors and found that the outcomes were all satisfactory. Consequently, we recommend taking into consideration the circulatory condition of the foot when deciding upon the surgical method for pincer nail deformity.

• Wind and Structures
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• v.26 no.4
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• pp.191-204
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• 2018

This article presents a study of the largest-ever (height = 220 m) cooling tower using the large eddy simulation (LES) method. Information about fluid fields around the tower and 3D aerodynamic time history in full construction process were obtained, and the wind pressure distribution along the entire tower predicted by the developed model was compared with standard curves and measured curves to validate the effectiveness of the simulating method. Based on that, average wind pressure distribution and characteristics of fluid fields in the construction process of ultra-large cooling tower were investigated. The characteristics of fluid fields in full construction process and their working principles were investigated based on wind speeds and vorticities under different construction conditions. Then, time domain characteristics of ultra-large cooling towers in full construction process, including fluctuating wind loads, extreme wind loads, lift and drag coefficients, and relationship of measuring points, were studied and fitting formula of extreme wind load as a function of height was developed based on the nonlinear least square method. Additionally, the frequency domain characteristics of wind loads on the constructing tower, including wind pressure power spectrum at typical measuring points, lift and drag power spectrum, circumferential correlations between typical measuring points, and vertical correlations of lift coefficient and drag coefficient, were analyzed. The results revealed that the random characteristics of fluctuating wind loads, as well as corresponding extreme wind pressure and power spectra curves, varied significantly and in real time with the height of the constructing tower. This study provides references for design of wind loads during construction period of ultra-large cooling towers.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.18 no.2
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• pp.180-194
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• 1985

The author investigated the history of oyster culture in Korea through examining old books and reports dealing with the fishery. Oysters have been produced in the all coastal areas in Korea, especially the center areas of production were the Hwangupo (Hamkyongbuk-do), Younghungman (Hamkyongnam-do), the estuary of Nakdonggang (Kyongsangnam-do), Kwangyangman, Haechangman, the estuary of Yongsangang (Chollanam-do), Yonghoto (Hwanghae-do) and the estuary of Uprockgang, where the large size oyster (more than 40cm in shell height) inhabited in form of groups. It was called by nine different names in the old times, Gul, Seukhwa and Moryeo were the most common names. The oyster was used as 46 kinds of medicinal stuff. The habitat forms of natural oyster can be distinguished to two types; one is that oyster is exposed to the air during the period of low tide (A-type), another is that oyster is not (B-type). The first oyster culture by the old books in Korea was started about 530 years ago as the bottom culture method derived from the A-type of oyster. After long years, the hanging culture method might have been started from the hint of the habitat form of B-type. The oyster culture in Korea developed based on the habitat forms of natural oyster at the biginning of 1900s. After World War II, the Korean government strongly recommded the laver farmers to culture oyster as relief measures. At that time, the stone culture method was mainly adopted. The quantity of oyster production is now about $15{\times}10^6{\sim}19{\times}10^6\;\frac{M}{T}$, and the half of oyster production including seed oyster is exported to the foreign countries.

• Journal of Chest Surgery
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• v.36 no.6
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• pp.444-447
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• 2003

Sleeve pneumonectomy can be a method of treatment in a selected patient with bronchogenic carcinoma involving carina. A 64 years old male with a history of mitral valve replacement via midsternotomy 13 years ago and resection of papilloma of the vocal cord 2 years ago. The patient was admitted due to blood-tinged sputum. Bronchoscopy and computerized tomogram of the chest revealed 3.5 cm mass at lower margin of the trachea and totally obstructing the left main bronchus. A biopsy revealed squamous cell carcinoma. He underwent left sleeve pneumonectomy through sequential bilateral thoracotomy without cardiopulmonary bypass, and the pathologic stage was T4N0M0 stage IIIB. The patient is being followed through the outpatient clinic in good general condition.

• Korean Journal of Biological Psychiatry
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• v.10 no.1
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• pp.80-84
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• 2003

Objective : Bipolar disorder is known to have strong genetic background and cellular immune activation. Based on the hypothesis that abnormalities of normal inhibitory control of T cell immunity can contribute to the pathophysiology of bipolar disorder, we investigated the relationship between the first exon at position +49(A/G) polymorphism of cytotoxic T lymphocyte antigen 4(CTLA4) gene and bipolar disorder. Method : Among the Korean patients diagnosed as bipolar disorder according to DSM-IV, 90 patients without serious medical illness, neurologic illness, hormonal disorder, or concomitant mental illness were selected. The normal control group consisted of 149 age-and sex-matched subjects without current or past history of autoimmune diseases or mental disorder. DNA was extracted from whole blood and the exon 1 region of CTLA-4 gene was amplified by polymerase chain reaction. Gene typing was performed using single strand conformation polymorphism. Results : There were no significant differences in genotype frequencies of G/G, G/A, and A/A between the patients with bipolar disorder and the control group(48.9% vs 46.3%, 44.4% vs 39.6%, and 6.7% vs 14.1%, respectively). There were no significant differences in allelic frequencies of G and A between the patients with bipolar disorder and the control group(71.1% vs 66.1%, and 28.9% vs 33.9%, respectively). Conclusion : This study did not show the association of exon 1 polymorphism of CTLA-4 gene with bipolar disorder.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1327-1331
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• 2014

Background: Electrical impedance tomography (EIT) is a new non-invasive, mobile screening method which does not use ionizing radiation to the human breast; allows conducting quantitative assessment of the images besides the visual interpretation. The aim of this study was to correlate the quantitative assessment and visual interpretation of breast electrical impedance tomographs and associated factors. Materials and Methods: One hundred and fifty mammography patients above 40 years and undergoing EIT were chosen using convenient sampling. Visual interpretation of the images was carried out by a radiologist with minimum of three years experience using the breast imaging - electrical impedance (BI-EIM) classification for detection of abnormalities. A set of thirty blinded EIT images were reinterpreted to determine the intra-rater reliability using kappa. Quantitative assessment was by comparison of the breast average electric conductivity with the norm and correlations with visual interpretation of the images were determined using Chi-square. One-way ANOVA was used to compare the mean electrical conductivity between groups and t-test was used for comparisons with pre-existing Caucasians statistics. Independent t-tests were applied to compare the mean electrical conductivity of women with factors like exogenous hormone use and family history of breast cancer. Results: The mean electrical conductivity of Malaysian women was significantly lower than that of Caucasians (p<0.05). Quantitative assessment of electrical impedance tomography was significantly related with visual interpretation of images of the breast (p<0.05). Conclusions: Quantitative assessment of electrical impedance tomography images was significantly related with visual interpretation.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1847-1850
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• 2013

We conducted a hospital case-control study by genotyping four potential functional single nucleotide polymorphisms (SNPs) to assess the association of Xeroderma pigmentosum complementation group F (XPF) with gastric cancer susceptibility, and role of XPF polymorphisms in combination with H.pylori infection in risk definition. A total of 331 patients with gastric cancer and 355 controls were collected. Four SNPs of XPF, rs180067, rs1799801, rs2276466 and rs744154, were genotyped by Taqman real-time PCR method with a 7900 HT sequence detector system. The gastric cancer patients were more likely to have smoking habit, a family history of cancer and H.pylori infection. We did not find any significant difference in the genotype distributions of XPF rs180067, rs1799801, rs2276466 and rs744154 between cases and controls. However, multivariate logistic analysis showed a non-significant decreased risk in patients carrying rs180067 G allele, rs1799801 T allele or rs2276466 T allele genotypes. A non-significant increased risk of gastric cancer was found in individuals carrying the rs744154 GG genotype. Stratification by H.pylori infection and smoking was not significantly different in polymorphisms of XPF rs180067, rs1799801, rs2276466 and rs744154. The four XPF SNPs did not show significant interaction with H.pylori infection and smoking status (P for interaction was 0.35 and 0.18, respectively). Our study indicated that polymorphisms in rs180067, rs1799801, rs2276466 and rs744154 may affect the risk of gastric cancer but further large sample size studies are needed to validate any association.

• Proceedings of the Mineralogical Society of Korea Conference
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• 2002.05a
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• pp.1-3
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• 2002

The eastward extension of the suture zone between the Sino-Korea and Yangtze cratons in the Korean Peninsula and Japanese islands remains debatable (Hiroi, 1981; Cluzel et al., 1991; Yin and Nie, 1993; Sohma and Kunugiza, 1993; Isozaki, 1997; Arakawa et at., 2000), and is related to our understanding of the continent-continent collision orogeny. The collision orogeny varies in tectono-metamorphic processes and the timing differs from place to place, as exemplified by the absence of coesite and micro-diamond in the Korean Peninsula and Japanese islands, because it is a long-lived process of more than several tens of million years from subduction to exhumation in the Wilson cycle, and because the suture zone extends more than several thousand kilometers with a curved shape from the Qinling area of China to the Hida highland area of Japan. Hiroi (1981) is the first paper to correlate the Unazuki metamorphic rocks of the Hida metamorphic belt in Japan with the Ogcheon belt in the Korean Peninsula based on the presence of 240 Ma medium P/T metamorphic rocks in both belts, but there is a lack of recent studies on this correlation. To resolve the correlationship, there are two approaches: 1) petrological studies characterizing the origin and P-T history of rocks and 2) in-situ micro-dating of fine-grained, zoned minerals of zircon, monazite, uraninite and thorite using the EPMA (U-Th-Pb chemical dating or CHIME depending on calibration method) and the SHRIMP (Sensitive High-resolution ion Microprobe) to decipher the timing of geological events. As a first step of these approaches, micro-dating was undertaken to rocks of the Hida metamorphic belt and its Mesozoic cover (Tetori Group) in the Hida highland area, central Japan.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.4
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• pp.1-15
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• 2020

Objectives : To investigate aggravating and mitigating factors of atopic dermatitis and to utilize the outcome in treatment planning. Methods : The research has a cross-sectional study design. Patients' SCORing Atopic Dermatitis (SCORAD) Index, demographic, physical characteristics, social history, serologic index and skin related instrumental measurements were analyzed with correlation and regression analysis method. Results : 48 patients in total were enrolled in the study. Skin Surface Hydration (SSH) and sex were found to be statistically significant aggravating and mitigating factors. As SSH increased, Total SCORAD (tSCORAD) and Objective SCORAD (oSCORAD) increased as well. As SSH decreased, tSCORAD and oSCORAD decreased as well. Female patient had a higher probability of suffering from severer subjective symptoms than that of male. Age, body mass index (BMI), alcohol consumption and smoking, transepidermal water loss (TEWL), IgE, IL-4, IL-5, IL-6, IFN-γ were found not to be statistically significant. There was no correlation between Subjective SCORAD (sSCORAD) and oSCORAD neither with Eczema Area and Severity Index (EASI). Conclusions : Increasing cutaneous moisture should be included in the treatment plan of atopic dermatitis. More emphasis should be put on alleviating subjective discomforts of female patients than that of male. Establishing separate strategies of managing objective eczema status and subjective discomforts respectively should be considered.