• The Plant Pathology Journal
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• 제37권5호
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• pp.446-454
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• 2021

Plant-parasitic nematodes are not only an important constraint on agricultural crop production, but also cause both direct and indirect damage to turfgrass, which is a ground cover plant. However, studies on plant-parasitic nematodes of turfgrass in Korea are scarce. A survey for plant-parasitic nematodes was carried out on 13 golf courses in Korea. The results yielded 28 species/taxa belonging to 16 genera and 12 families of plant-parasitic nematodes. Among the isolated species, Helicotylenchus microlobus, Mesocriconema nebraskense, Tylenchorhynchus claytoni, Mesocriconema sp., and Meloidogyne graminicola were the most prevalent species in all management zones. Twelve species were new records of plant-parasitic nematodes in Korea. Highest maximum densities were showed by T. claytoni, Paratylenchus nanus, M. nebraskense, M. graminicola, and H. microlobus. Diversity (H'), was significantly higher in fairways compared to tees and greens, though species evenness (J') and dominance (D) showed no statistically significant differences. This information is crucial in nematode problem diagnosis, and the subsequent formulation of management strategies.

• Steel and Composite Structures
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• 제48권1호
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• pp.73-88
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• 2023

This paper presents a novel implicit level set method for topology optimization of functionally graded (FG) structures with pre-existing discontinuities (pre-cracks) using radial basis functions (RBF). The mathematical formulation of the optimization problem is developed by incorporating RBF-based nodal densities as design variables and minimizing compliance as the objective function. To accurately capture crack-tip behavior, crack-tip enrichment functions are introduced, and an eXtended Finite Element Method (X-FEM) is employed for analyzing the mechanical response of FG structures with strong discontinuities. The enforcement of boundary conditions is achieved using the Hamilton-Jacobi method. The study provides detailed mathematical expressions for topology optimization of systems with defects using FG materials. Numerical examples are presented to demonstrate the efficiency and reliability of the proposed methodology.

• 터널과지하공간
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• 제9권1호
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• pp.1-11
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• 1999

열-수리-역학적 상호작용을 해석하기 위한 유한요소 코드가 개발되었다. 이 코드는 Noorishad(1984)에 의해 제시된 유한요소 수식화에 기초하였으며, 절리 거동은 Goodman 의 절리 구성 모델로 모사되었다. 개발된 코드가 각각 절리가 있거나 없는 두가지 종류의 수갱 모델에 대한 T-H-M 상호작용 해석에 적용되었다. 절 리가 없는 모델에 대해서, 수갱벽면으로부터 바깥 방향으로 온도 증가가 뚜렷이 나타났다. 절 리가 있는 모델에 대해서, 절리의 닫힘이 열팽창에 의해 생겼으며, 물이 암석기질보다 낮은 열 전도도와 높은 비열용량을 보이기 때문에 절리를 따라 온도 분포가 상대적으로 낮게 나타났다. 또한 절리 내에서의 열 유동의 영향이 암반내에서의 수리유동의 영향보다 더 크다고 결론내릴 수 있다.

• 대한조선학회논문집
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• 제29권2호
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• pp.132-139
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• 1992

기하학적 비선형 해석과정에서 일반적인 방법으로는 연속적인 하중증분단계의 기하학적 변위증분에서 절점회전이 미소하다는 가정에 의해 제한되어 접선강성행렬을 유도하고 유한회전의 영향을 증분평형 방정식의 반복계산하는 과정에서 고려하는 방법이 사용되고 있다. 그리고 개선된 방법으로는 미소회전증분의 가정을 무시하고 유한회전증분의 영향을 고려하여 접선강성행렬을 유도하는 방법이 Surana, Onate 및 Dvorkin 등에 의해서 개발되었다. 유한 회전을 고려하는 방법에서 Surana는 비선형 절점 회전함수를 가정하여 강성메트릭스를 유도하였으며 Onate와 Dvorkin은 전체좌표에서 회전각에 대한 회전행렬의 2차항까지를 고려한 강성메트릭스를 유도하였다. 본 논문에서는 유한요소의 기하학적 위치를 나타내는 변위함수의 방향 벡터를 삼각함수로 표현하여 연속적인 하중증분 사이의 방향벡터 증분을Tayler의 급수로 2차항까지 전개하므로써 비선형 회전 증분을 고려한 쉘 요소를 개발하였다. 기하학적 비선형 해석과정은 연속체 운동의 증분이론을 도입하여 Total Lagrange(T.L.)수식과 Updated Lagrange(U.L.)수식으로 비선형 거동을 해석하였다.

• IMMUNE NETWORK
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• 제23권2호
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• pp.16.1-16.19
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• 2023

Bacillus Calmette-Guerin (BCG) vaccine is the only licensed vaccine for tuberculosis (TB) prevention. Previously, our group demonstrated the vaccine potential of Rv0351 and Rv3628 against Mycobacterium tuberculosis (Mtb) infection by directing Th1-biased CD4⁺ T cells co-expressing IFN-γ, TNF-α, and IL-2 in the lungs. Here, we assessed immunogenicity and vaccine potential of the combined Ags (Rv0351/Rv3628) formulated in different adjuvants as subunit booster in BCG-primed mice against hypervirulent clinical Mtb strain K (Mtb K). Compared to BCG-only or subunit-only vaccine, BCG prime and subunit boost regimen exhibited significantly enhanced Th1 response. Next, we evaluated the immunogenicity to the combined Ags when formulated with four different types of monophosphoryl lipid A (MPL)-based adjuvants: 1) dimethyldioctadecylammonium bromide (DDA), MPL, and trehalose dicorynomycolate (TDM) in liposome form (DMT), 2) MPL and Poly I:C in liposome form (MP), 3) MPL, Poly I:C, and QS21 in liposome form (MPQ), and 4) MPL and Poly I:C in squalene emulsion form (MPS). MPQ and MPS displayed greater adjuvancity in Th1 induction than DMT or MP did. Especially, BCG prime and subunit-MPS boost regimen significantly reduced the bacterial loads and pulmonary inflammation against Mtb K infection when compared to BCG-only vaccine at a chronic stage of TB disease. Collectively, our findings highlighted the importance of adjuvant components and formulation to induce the enhanced protection with an optimal Th1 response.

• 한국약용작물학회지
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• 제26권4호
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• pp.317-327
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• 2018

Background: The root of Angelica gigas Nakai is used as a traditional herbal medicine in Korea for the treatment of many diseases. However, the poor water solubility of the active components in A. gigas Nakai is a major obstacle to its bioavailability. Methods and Results: This work aimed at enhancing the solubility of the active compounds of A. gigas Nakai by a chemical (using a surfactant) and physical (hot melt extrusion, HME) crosslinking method. Fourier transform infrared spectroscopy revealed multiple peaks in the case of the extrudate solids, attributable to new functional groups including carboxylic acid, alkynes, and benzene derivatives. Differential scanning calorimetry analysis showed that the extrudate soilid had a lower glass transition temperature ($T_g$) and enthalpy (${\Delta}H$) ($T_g:43^{\circ}C$, ${\Delta}H$ : < 6 J/g) as compared to the non-extrudate ($T_g:68.5^{\circ}C$, ${\Delta}H:123.2$) formulations. X-ray powder diffraction analysis revealed the amorphization of crystalline materials in the extrudate solid. In addition, enhanced solubility (53%), nanonization (403 nm), and a higher amount of extracted phenolic compounds were achieved in the extrudate solid than in the non-extrudate (solubility : 36%, nanonization : 1,499 nm) formulation. Among the different extrudates, acetic acid and span 80 mediated formulations showed superior extractions efficiency. Conclusions: HME successfully enhanced the production of amorphous nano dispersions of phenolic compound including decursin from extrudate solid formulations.

• Elastomers and Composites
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• 제49권2호
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• pp.160-166
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• 2014

자동차 선도장용으로 알루미늄 페이스트를 사용하여 6가지 베이스코트용 포뮬레이션이 설계되었다. 알루미늄 페이스트는 pancake 형태의 금속 안료인 #501, #801, #601와 cornflake 형태의 금속 안료인 #750, #770, #790가 사용되었다. 베이스코트의 상대적인 경화 밀도는 #501, #801, #601, #750, #770, #790 순으로 증가하였다. T-bending, 내충격성, 테이핑 부착력은 경화 밀도의 증가에 따라 향상되었다. Cornflake 형태의 안료에 대한 외관(combined factor) 테스트에서 입자가 가장 작은 #790이 다른 두 가지(#750, #770)와 비교하였을 때 가장 좋은 combined factor를 보여 주었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집C
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• pp.492-497
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• 2001

In the finite element analysis of metal forming processes using general Lagrangian formulation, element nodes in the mesh move and elements are distorted as the material is deformed. The excessive degeneracy of mesh interrupts finite element analysis and thus increases the error of plastic deformation energy. In this study, a remeshing scheme using so-called mesh compression method is proposed to effectively analyze the flash which is generated usually in hot forging processes. In order to verify the effectiveness of the method, several examples are tested in two-dimensional and three-dimensional problems.

• Structural Engineering and Mechanics
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• 제13권4호
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• pp.387-410
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• 2002

Formulation of an 8 nodes assumed strain shell element is presented for the analysis of shells. The stiffness matrix based on the Mindlin-Reissner theory is analytically integrated through the thickness. The element is free of membrane and shear locking behavior by using the assumed strain method such that the element performs very well in modeling of thin shell structures. The material is assumed to be isotropic and laminated composite. The element has six degrees of freedom per node and can model the stiffened plates and shells. A great number of numerical testing carried out for the validation of present 8 node shell element are in good agreement with references.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1999년도 춘계학술대회논문집
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• pp.171-175
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• 1999

the high temperature deformation behavior of 304 stainless steel was characterized by the hot torsion test. Continuous deformation was carried out at the temperature ranges 900-110$0^{\circ}C$ and the strain rate ranges 5x10-2~5/sec. The formulation of the flow stress curves was developed as subtraction form which was based on dynamic softening mechanisms The volume fraction of dynamic recrystallization and the mean grain size could be expressed as a function of deformation variables temperature (T) strain ($\varepsilon$) strain rate ($\varepsilon$) The calculated values of flow stress and mean grain size could be well matched with experimental values.