• The Journal of Korean Physical Therapy
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• v.10 no.2
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• pp.41-55
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• 1998

An analysis of 87 stroke Patients who were enrolled in 7 hospitals in cities of Pusan, Taegu, Kumi, and Andong from January 1 to May 31, 1998 was conducted using the modified Barthel Index(BI) and the adapted PULSES profile index(PS) to evaluate their function. Patients were examined at the following intervals : Initial assessment, one month after initial, at discharge, and ore month after discharge. The mean BI score of patients initial assessment was 26.32. and that of PS was 17.34. There were statistically significant between initial score and one month after initial (16.61 : p<0.001), at discharge(33.51 : p<0,001), one month after discharge(43,56 : p<0.001). PS scores were also improved significantly(-2.1, -3. 94, and -5.52(p<0.001), and BI score between discharge and one month after discharge wag significant improvement(10.06 : p <0.001) and in PS score(-1,57 : p<0.001). Age and BI scone were significantly associated with the improved in BI score between initial and discharge (T3-T1)(p<0.05). Below age forty and the lower initial BI score showed significantly higher improvement(T3-T1) after physical therapy(p<0.05). Initial BI score, BI score at discharge, and religion were significantly associated with the improvement of BI score between initial and one month after discharge(T4-T1)(p<0.05). The lower initial BI score, the high. BI score at discharge, and the religious showed significantly higher improvement(T4-T1)(p<0.05). BI score at discharge and religion were significantly associated with the improvement of BI score between at discharge and one month after discharge(T4-T3)(p<0.05). The lower BI score at discharge, the religious showed significantly higher improvement(T4-T3)(p<0.05) Initial PS score were significantly associated with the improved in PS score between initial and discharge(T3-T1)(p<0.05). The higher initial PS score showed significantly hier improvement(T3-T1)(p<0.05). Initial PS score, Bi score at discharge, and patient's attitude for physical therapy after discharge were significantly associated with the improvement of PS score between initial and one month after discharge(T4- T1)(p <0.05). The higher initial PS scorer the lower PS score at discharge, patient's positive attitude for physical therapy after discharge showed significantly higher improvement(T4-T1)(p<0.05). PS score at discharge, Patient's attitude for Physical therapy after discharge were significantly associated with the improvement of PS score between discharge and one month after discharge(T4-T3)(p<0.05). The higher PS score at discharge, patient's positive attitude for physical therapy after discharge showed significantly higher improvement(T4-T3)(p<0.05). In conclusion, Initial BI score, BI score at discharge, age, and religion were significantly associated with BI score improvement. initial PS score, BI score discharge, and patient's attitude for physical therapy after discharge were significantly associated with PS score improvement in stroke patients.

• Korean Journal of Agricultural Science
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• v.5 no.2
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• pp.115-119
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• 1978

To improve the feed value of rice straw, Tongil type rice straw and Persicaria Thunbergii Gross var. coreana Gross ex Nakai were mixed in the ratios of 10 : 90 (T1), 20 : 80 (T2), 30 : 70 (T3) and 40 : 60 (T4) in fresh weight and ensiled for 6 weeks. The chemical composition of fresh materials and silage, the organic acid contents and pH in silage were determined. And the results obtained were summarized as follow: 1. The crude protein content in rice straw was 8.18% of DM basis and that in Persicaria Thunbergii was 14.47%. And the nitrogen-free extract content in rice straw was 44.66% and.. that in Persicaria Thunbergii was 51.13%. 2. The optimum moisture contents were appeared in T2 as 72.12% and T3 as 66.43%. Considerably high crude protein contents were determined from all of treatments. 3. The pH of silage was varied from pH 3.8 of T1 to pH 4.5 of T2. And Total organic acid contents were increased from T1 to T4, but the percentage of lactic acid contents to total acid contents were decreased. 4. It was concluded that good quality silage could be made from rice straw with Persicaria Thunbergii and the best ratios of rice straw: Persicaria Thunbergii were between 20 : 80 and 30 : 70 in fresh weight.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5653-5657
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• 2012

Objectives: To investigate the effect of glycopeptide-preferring polypeptide GalNAc transferase 1 (ppGalNAc T1 ) targeted RNA interference (RNAi) on the growth and migration of human bladder carcinoma EJ cells in vitro and in vivo. Methods: DNA microarray assays were performed to determine ppGalNAc Ts(ppGalNAc T1-9) expression in human bladder cancer and normal bladder tissues. We transfected the EJ bladder cancer cell line with well-designed ppGalNAc T1 siRNA. Boyden chamber and Wound healing assays were used to investigate changes of shppGalNAc T1-EJ cell migration. Proliferation of shppGalNAc T1-EJ cells in vitro was assessed using [3H]-thymidine incorporation assay and soft agar colony formation assays. Subcutaneous bladder tumors in BALB/c nude mice were induced by inoculation of shppGalNAc T1-EJ cells and after inoculation diameters of tumors were measured every 5 days to determine gross tumor volumes. Results: ppGalNAc T1 mRNA in bladder cancer tissues was 11.2-fold higher than in normal bladder tissues. When ppGalNAc T1 expression in EJ cells was knocked down through transfection by pSUPER-shppGalNAc T1 vector, markedly reduced incorporation of [3H]-thymidine into DNA of EJ cells was observed at all time points compared with the empty vector transfected control cells. However, ppGalNAc T1 knockdown did not significantly inhibited cell migration (only 12.3%). Silenced ppGalNAc T1 expression significantly inhibited subcutaneous tumor growth compared with the control groups injected with empty vector transfected control cells. At the end of observation course (40 days), the inhibitory rate of cancerous growth for ppGalNAc T1 knockdown was 52.5%. Conclusion: ppGalNAc T1 might be a potential novel marker for human bladder cancer. Although ppGalNAc T1 knockdown caused no remarkable change in cell migration, silenced expression significantly inhibited proliferation and tumor growth of the bladder cancer EJ cell line.

• Journal of Korean Society of Forest Science
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• v.96 no.1
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• pp.29-33
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• 2007

The objective of this research was to provide basic information of Thuja orientalis stand for prediction system, which consists of the best model of diameter and basal area. Data was from cores of 45 sample trees of Thuja orientalis stand that was designated as a natural monument (No. 62) in Yeongcheon, Chungbuk. Of the projection functions tested, polymorphic equation using the overlapping data showed higher precision of the fitting than anamorphic equation using. In diameter growth, Schumacher polymorphic equation of $D_2={\exp}({\ln}(D_1)(T_1/T_2)^{0.4495}+3.8535(1-(T_1/T_2)^{0.4495}))$, and in basal area growth, Schumacher polymorphic equation of $BA_2={\exp}({\ln}(BA_1)(T_1/T_2)^{0.1235}+11.3793(1-(T_1/T_2)^{0.1235}))$ showed the highest precision of the fitting among them. The equation, therefore, could be available as basic information for estimation of growth and management of Thuja orientalis stand.

• Korean Journal of Ichthyology
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• v.20 no.1
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• pp.21-27
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• 2008

A total sample of 215 specimens of the Iksookimia koreensis was collected monthly from June 2004 to June 2005 in the Namdae stream, Cheorwon-gun, Gangwon-do, Korea. The age of every individual sample was estimated by the number of annual rings on the scales. A significant decrease of gonadosomatic index was noted between May and June reflecting the reproduction during this period. I. koreensis exhibited a strong bias to female (female : male, 1 : 0.56). The maximum age observed was 3 years old for male & female, both. The von Bertalanffy growth curves were expressed as $L_t=126.30[1-\exp\{-0.576(t+0.940)\}]$ for females and $L_t=100.19[1-\exp\{-1.119(t+0.695)\}]$ for males.Growth curve of weight was expressed as $W_t=11.567[1-\exp\{-0.576(t+0.940)\}]^{3.199}$ for females, $W_t=5.514[1-\exp\{-1.119(t+0.695)\}]^{3.199}$ for males. On the other hand, a significant difference in the growth rate between both sexes was found(i.e. females grew faster than males).

• Food Science of Animal Resources
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• v.27 no.3
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• pp.277-283
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• 2007

This study was conducted to determine the effect of mugwort powder supplementation on the fattening performance and carcass characteristics during a 14 month period (from 14 months to 27 months after birth) in 32 heads of fattening Hanwoo. Fattening Hanwoos were randomly assigned 4 treatments (8 heads/treatment): C-1 [(control (0%) with Hanwoo steers)], C-2 [(control (0%) with Hanwoo heifers)], T-1 (supplementation with 2.0% mugwort powder with Hanwoo steers) and T-2(supplementation with 2.0% mugwort powder with Hanwoo heifers). The final body weights for C-1, C-2, T-1 and T-2 at 27 months were 648.6kg, 623.1kg, 663.3kg and 620.7kg, respectively. The total gain and the daily gain were highest in the T-1 group (342.4 kg, 0.88 kg). Hanwoo steers were not significantly different from Hanwoo heifers. The feed intake for the C-1, C-2, T-1 and T-2 groups were 9.35 kg, 9.09 kg, 10.08 kg and 9.69 kg, with the T-1 value being highest. The feed conversion ratios were as follows: C-1 (11.28) > T-1 (11.48) > C-2 (11.52) > T-2 (12.57). The concentrations of total cholesterol, GOT, GPT, glucose and BUN in blood serum during the fattening period were higher after than before the experiment The total cholesterol, GOT and glucose after completion of the experiment were higher in the treatment groups than the control groups (p<0.05). The carcass body weight was higher in the treatment groups than the control groups. The back fat thickness was lower in the treatment groups (12.75-14.75mm) than the control groups (15.76-16.00mm), and the longissimus muscle area was higher in the treatment groups $(84.25-87.88cm^2)$ than the control groups $(84.00-85.25cm^2)$ with the highest over-all values in the T-1 group (p<0.05). The yield grade and quality grade point were higher in the treatment groups (2.02-2.50, 2.85-3.05 point, respectively) than the control groups (1.80, 2.55-2.80 point, respectively). In conclusion, the effects of feeding dietary mugwort powder to Hanwoo steers improved the ADG, carcass body weight, longissimus muscle area and quality grade.

• the MEAT Journal
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• s.34 winter
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• pp.40-47
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• 2007

This study was conducted to determine the effect of L. casei KCTC 3109 on physico-chemical characteristics and TBARS values of fermented pork meat. Each pork meat were allotted to two treatments ; Control (0%), T1 (supplemented with L. casei KCTC 3109 10%). The pH tenderness and water holding capacity (WHC) of T1 were higher than those of control (p<0.05), cooking loss of control was higher than T1. Water content, crude fat and ash were not significantly different, crude protein was higher in T1 compared with control (p<0.05). L*, a* and b* values of control were higher than those of T1 (p<0.05). TBARS values was higher in T1 (0.02 MA mg/1,000 g) than control (0.19 MA mg/1,000 g) (p<0.05).

• Food Science of Animal Resources
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• v.26 no.2
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• pp.218-222
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• 2006

This study was conducted to determine the effect of L. casei KCTC 3109 on physico-chemical characteristics and TBARS values of fermented pork meat. Each pork meat were allotted to two treatments ; Control (0%), $T_1$ (supplemented with L. casei KCTC 3109 10%). The pH tenderness and water holding capacity (WHC) of $T_1$ were higher than those of control (p<0.05), cooking loss of control was higher than $T_1$. Water content, crude Int and ash were not significantly different crude protein was higher in $T_1$ compared with control (p<0.05). $L^*,\;a^*$ and $b^*$ values of control were higher than those of $T_1$ (p<0.05). TBARS values was higher in $T_1$(0.02 MA mg/1,000 g) than control (0.19 MA mg/1,000g) (P<0.05).

• Journal of Korean Medicine for Obesity Research
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• v.20 no.1
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• pp.1-9
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• 2020

Objectives: Artemisinin and its derivatives extracted from Artemisia annua, a Chinese herbal medicine, have variable biological effects due to structural differences. Up to date, the anti-obesity effect of dihydroartemisinin (DHA), a derivative of artemisinin, is unknown. The purpose of this study was to investigate the anti-adipogenic and lipolytic effects of DHA on 3T3-L1 preadipocytes. Methods: Oil Red O staining and AdipoRed assay were used to measure lipid accumulation and triglyceride (TG) content in 3T3-L1 cells, respectively. Cell count analysis was used to determine the cytotoxicity of 3T3-L1 cells. Western blot and real-time reverse transcription polymerase chain reaction analyses were used to analyze the expression of protein and mRNA in 3T3-L1 cells, respectively. Results: DHA at 5 μM markedly inhibited lipid accumulation and reduced TG content in differentiating 3T3-L1 cells with no cytotoxicity. Furthermore, DHA at 5 μM inhibited the expression of CCAAT/enhancer-binding protein-α (C/EBP-α), peroxisome proliferator-activated receptor-γ (PPAR-γ), fatty acid synthase (FAS), and perilipin A as well as the phosphorylation of signal transducer and activator of transcription-3 (STAT-3) in differentiating 3T3-L1 cells. Moreover, while DHA at 5 μM had no effect on the mRNA expression of adiponectin, it strongly suppressed that of leptin in differentiating 3T3-L1 cells. However, DHA at 5 μM had no lipolytic effect on differentiated 3T3-L1 cells, as assessed by no enhancement of glycerol release. Conclusions: These results demonstrate that DHA at 5 μM has a strong anti-adipogenic effect on differentiating 3T3-L1 cells through the reduced expression and phosphorylation of C/EBP-α, PPAR-γ, FAS, perilipin A, and STAT-3.

• Journal of Veterinary Clinics
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• v.16 no.2
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• pp.332-338
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• 1999

This study was carried out to investigate weight gain and prevention of diarrhea in suckling calves which were injected with recombinant bovine somatopropin (rBST). A total of 101 breeding cows were assigned to the six groups according to the administered dosage and injected time, respectively. Groups T-1, T-3, T-4 and T-6 were injected starting 1 week before calving and groups T-2 and T-5 were injected on the calving day. The six groups were injected five times at two week intervals. Groups T-1 and T-2 were injected with 250mg composite rBST, Group T-3 was injected with 375 mg composite rBST. Groups T-4 and T-5 were injected with 500mg composite rBST, And group T-6 was injected with 500mg rBST-S. The control group was not injected with BST. The groups injected with 500 mg BrST had a lower rate of morbidity from diarrhea than the control group or the groups injected with 250 mg rBST (T-1 and T-2). Weight gain was higher in group T-4 than in the control group or groups T-1 and T-2. In Korean Native Cattle, the total weight gain was greater in group T-4 than in the control group (p<0.05). In crossbred cows, total weight gain was the highest in group T-4, and the total weight gain rate was greater than in group T-4 and the control group (p<0.05). The results of the hematological values showed that injections of rBST did not affect the level of the RBC, TP and BUN in the breeding cows at 9 weeks after postpartum or the neonatal calves. The results of this study indicate that injecting breeding cows with 500 mg rBST before calving would be effective in the preventing of diarrhea and in increasing weight gain of calves from birth to weaning.