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Parental Age-Related Risk of Retinoblastoma in Iranian Children

  • Saremi, Leila;Imani, Saber;Rostaminia, Maryam;Nadeali, Zakiye
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2847-2850
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    • 2014
  • Background: Retinoblastoma is a rare malignant intraocular neoplasm. About 90% of cases feature a germline mutation in the RB1 gene and these will develop retinoblastoma during their early childhood. An association between mutations in germline cells and aging has been demonstrated. This suggests a higher incidence of childhood cancer including retinoblastoma among children of older parents. Materials and Methods: In the present study we aimed to determine the association of paternal and maternal age with an increased risk of retinoblastoma in a case-control study in Iranian population. The study was carried out on 240 persons who were born during 1984-2012 in Mahak and Mofid hospitals in Tehran, Iran. The statistical analysis included studying the mean age of parents and in order to know whether parental age of patients is different from parental age of control group, (t-test) compare averages test is used perfectly. By binary logistic regression, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Results: The results of statistical analysis including the study of mean parental age by the use of (t-test) compare averages test showed a significant difference between parental ages of patients and controls. Logistic regression showed that coefficients were significant for maternal but not paternal age. Conclusions: Our findings indicate that advanced maternal age can increase the risk of retinoblastoma in offspring, but the paternal age has no significant effect.

A Study of Center Longitudinal Shunt-Series Coupling Slot Fed by Asymmetric Compound Iris for Waveguide Slot Coupler (도파관 슬롯 커플러용 비대칭 복합 아이리스에 의해 급전되는 중심 종방향 션트-시리즈 결합 슬롯에 관한 연구)

  • Kim, Byung-Mun;Ko, Ji-Hwan;Cho, Young-Ki
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.6
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    • pp.586-594
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    • 2013
  • This paper proposes a new coupling element of microwave slot coupler for designing waveguide slot array which can reduce the effect of undesired higher order mode coupling between coupling and radiating slots in the branch waveguide. The proposed device is composed of a centered longitudinal shunt-series coupling slot at the center of broad wall shared by two crossed rectangular waveguides and an asymmetric compound iris that excites the coupling slot. We first have obtained scattering parameters for the proposed coupler by use of EM S/W tool HFSS and then extracted the parameters of T- network equivalent circuit for the coupling slot. We also have analyzed the resonant properties such as resonant length and normalized admittance by changing the geometrical dimensions. The measured results for the fabricated coupler with short-circuited block ${\lambda}_g/4$ away from the coupling slot are well agreed with the simulated ones.

Effects of Sheng Hua Tang on Uterine Involution and Ovarian Activity in Postpartum Dairy Cows

  • Lee, K.H.;Lee, Y.T.;Chen, T.C.;Yeh, C.C.;Chen, J.Y.;Liu, L.Y.;Chi, C.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.9
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    • pp.1247-1254
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    • 2013
  • The effects of Sheng Hua Tang (SHT) on uterine involution and ovarian activity were investigated in postpartum dairy cows. SHT (70 g) was given to dairy cows (n = 10) to evaluate its effects for five days from the first postpartum day. Postpartum cows fed with a basal diet without SHT were used as the control group (n = 10). Ultrasounds and blood tests were recorded for four weeks from postpartum day seven with a 3-d interval. The results showed that the areas and diameters of endometria were significantly (p<0.01) reduced in the group that received SHT compared to the control group on the seventh postpartum day. The group that received SHT had an intrauterine fluid volume mean of $1.2{\pm}0.6cm^3$, which was significantly lower than that of the control group, $2.3{\pm}0.8cm^3$ (p<0.01) on the 13th postpartum day. In addition, the uterine tension score was a mean of $1.0{\pm}0.0$ in the group that received SHT, which was also significantly lower than that of the control group, $1.5{\pm}0.5$ (p<0.01) on the 19th postpartum day. Taken together, the Chinese herbal medicine remedy, SHT, promoted uterine involution and ovarian activity in postpartum dairy cows.

Isolation and Characterization of Reovirus in Korea (한국에 분포하는 레오바이러스의 분리 및 동정)

  • Song, Ki-Joon;Kang, Byung-Chul;Lee, Young-Eun;Baek, Luck-Ju;Lee, Yong-Ju;Song, Jin-Won
    • The Journal of Korean Society of Virology
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    • v.29 no.2
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    • pp.65-74
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    • 1999
  • Reovirus was found to inhabit both the respiratory and the enteric tract of human and animals. The genome of reovirus comprises 10 segments of double-stranded RNA, total size 24 kbp. Nine strains of reovirus were isolated from human and field mice in Korea. Aseptically collected sera from human and lung tissues from field mice were used for virus isolation. For serotype determination, hemagglutination inhibition test was used, and three strains were confirmed to type 2 and six strains to type 3. To determine the genomic diversity and molecular phylogeny of reoviruses isolated in Korea, part of S4 genomic segment of reovirus was enzymatically amplified and directly sequenced. In nucleotide level, Apo98-35 strain showed 15.4%, 19.3%, and 14.4% differences compared to type 1 (T1L, Lang), type 2 (T2J), and type 3 reference strains, respectively. In amino acid level, Apo98-35 strain showed 10.5%, 13.7%, and 9.5% differences compared to type 1, type 2, and type 3 reference strains, respectively. Using the maximum parsimony method based on 285 bp spaning region of the S4 genomic segment, phylogenetic analysis indicated that Apo98-35 from Korea formed different phylogenetic branch. Our data obtained by sequence and phylogenetic analyses of reoviruses are consistent with the distinct geographically dependent evolution of reoviruses in Korea.

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Establishing Automated Mapping/Facilities Management System Using PC-CAD (PC용 CAD를 이용한 단지기반시설 정보화)

  • 이규석;안승만;탁형렬
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.15 no.2
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    • pp.141-148
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    • 1997
  • Continuous development of Personal Computer(PC) combined with the decrease of price and the expansion of operating system in PC like Windows 95, and Windows N/T makes it possible for the user to consider PC-bas-ed Automated Happing/Facilities Management (AM/FM) system. Therefore, the purpose of this study is to establish a PC-based data automation system of pipe infrastructures-water, sewer, and drainage-and road in Korea Land Corporation. In order to achieve this goal, relevant literature survey was done first. Secondly, the study site was determined by discussion with Korea Land Institute. Thirdly, PC-based CAD software for AM/FM in the world market were surveyed, and AutoCAD Map was selected because KLC had been using hundreds of AutoCAD copies already. After that user needs assessment was done to visit on-site office, local branch office, and the corresponding city office for the system design and database design. After the graphic data were digitized and the attribute data were entered into the batabase, the data automation system was established, and tested for application. Finally, the guidelines and problems for PC-based data automation in AM/FM was discussed.

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Tracing Water Pollution Source using FDC and Exceedance Rate in Cheongmicheon Watershed (FDC 및 초과율을 이용한 청미천 유역에서의 오염원 추적)

  • Kim, Yeon-Su;Kim, Sang-Ho;Lee, Chang-Hee
    • Journal of Wetlands Research
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    • v.20 no.2
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    • pp.136-144
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    • 2018
  • The Ministry of the Environment conducts a water environment management plan and TMDL(Total Maximum Daily Load) for integrated watershed management, and determines whether the target water quality is achieved using water quality monitoring data. The concentration of monitoring points located in the downstream of the watershed is the outcome of complicated mechanisms such as influx of pollutants from the tributaries of the watershed and self-purification of river water. The purpose of this study is to analyze the effect of main stream and tributary water quality on the target water quality point using the water pollution source tracking and exceedance rate of watershed. In this study, FDC and exceedance rate analysis were performed on six water quality items including BOD and T-P, which are the targets of TMDL. Water quality items and points affecting the target water quality point were derived from flow rate. In this study, the pollution source tracking through FDC analysis and exceedance rate analysis will be able to establish more efficiently the water quality management strategy for each branch to achieve the target water quality.

Visual Monitoring System of Multi-Hosts Behavior for Trustworthiness with Mobile Cloud

  • Song, Eun-Ha;Kim, Hyun-Woo;Jeong, Young-Sik
    • Journal of Information Processing Systems
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    • v.8 no.2
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    • pp.347-358
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    • 2012
  • Recently, security researches have been processed on the method to cover a broader range of hacking attacks at the low level in the perspective of hardware. This system security applies not only to individuals' computer systems but also to cloud environments. "Cloud" concerns operations on the web. Therefore it is exposed to a lot of risks and the security of its spaces where data is stored is vulnerable. Accordingly, in order to reduce threat factors to security, the TCG proposed a highly reliable platform based on a semiconductor-chip, the TPM. However, there have been no technologies up to date that enables a real-time visual monitoring of the security status of a PC that is operated based on the TPM. And the TPB has provided the function in a visual method to monitor system status and resources only for the system behavior of a single host. Therefore, this paper will propose a m-TMS (Mobile Trusted Monitoring System) that monitors the trusted state of a computing environment in which a TPM chip-based TPB is mounted and the current status of its system resources in a mobile device environment resulting from the development of network service technology. The m-TMS is provided to users so that system resources of CPU, RAM, and process, which are the monitoring objects in a computer system, may be monitored. Moreover, converting and detouring single entities like a PC or target addresses, which are attack pattern methods that pose a threat to the computer system security, are combined. The branch instruction trace function is monitored using a BiT Profiling tool through which processes attacked or those suspected of being attacked may be traced, thereby enabling users to actively respond.

Quality Assessment of the Soils Used for Urban Agriculture in Seoul and its Vicinity

  • Lim, Ga-Hee;Park, Sol-Yi;Jeon, Da-Som;Yoon, Jung-Hwan;Lee, Dan-Bi;Oh, Jun-Seok;Kim, Kye-Hoon
    • Korean Journal of Soil Science and Fertilizer
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    • v.49 no.5
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    • pp.572-576
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    • 2016
  • Soil quality assessment is an important tool for environmental management in an agricultural field. It can be used to evaluate the health of the soils and to establish the basis for sustainable urban agriculture and soil management. For this study, the chemical properties of the soils used for urban agriculture were examined. Results of the soil analysis for chemical properties were applied to soil quality assessment system, which is composed of principal component analysis, application to scoring function and derivation of soil quality index (SQI). Soil pH, electrical conductivity (EC), organic matter (OM), total nitrogen (T-N) were determined for minimum data set (MDS) according to principal component analysis. Based on the results of scoring for four indicators (pH, EC, OM, T-N), soil pH was the indicator that needs the most urgent management. Results of SQI derivation showed that many of the urban farms appeared to be insufficient score in comprehensive soil quality assessment. In conclusion, soil management practices based on scores derived from soil chemical indicators need to be carried out to maintain sustainable urban agricultural soil environment and to provide easy-to-understand information to urban farmers.

Traffic Accident Reduction Effects of the All-Red Clearance Interval (ARCI) Operation (전적색신호시간 운영에 따른 교통사고 감소효과)

  • Park, Byung-Ho;Jung, Yong-Il;Kim, Kyung-Hwan
    • Journal of Korean Society of Transportation
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    • v.30 no.2
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    • pp.21-27
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    • 2012
  • This study deals with the relationships between signal operation and traffic accident of signalized intersections. The objective of this study is to analyze the traffic accident reduction effects on the operation of all-red clearance interval (ARCI). This study gives particular attentions to evaluating the traffic accident reduction effects of ARCI at 37 signalized intersections in Cheongju using before-after evaluation with comparison group. The main results are as follows. First, the number of traffic accidents, fatalities and injuries has changed before operating ARCI and thereafter. Second, the result of before-and-after evaluation with comparison group showed that the number of accidents was reduced by 20.0% and that the number of fatalities and injuries was reduced by 28.0%. Finally, reduction effects from operating ARCI were evaluated to be 6.0~35.0% in the number of accidents and 18.0~37.0% in the number of fatalities and injuries.

Spatio-Temporal Distribution of Euphausiids in Korean Waters in 2016 (2016년 한국 근해 난바다곤쟁이류의 시·공간적 분포)

  • Lee, Bo Ram;Park, Wongyu;Lee, Hae Won;Choi, Jung Hwa;Oh, Taeg Yun;Kim, Doo Nam
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.4
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    • pp.456-466
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    • 2021
  • The distribution and abundance of euphausiids were investigated in Korean waters in 2016. Euphausiids were sampled with a Bongo net. A CTD (Sea Bird Electronics 9 plus) measured the water temperature and salinity while sampling. Mean water temperature ranged from 4.2-31.0℃. The highest temperatures occur in September and lowest temperatures in February. The mean water salinity ranged from 27.9-34.8 psu, with the highest salinities in March and lowest in September. Euphausiid species in group W consisted of four species. Among the euphausiid species, Euphausia pacifica was the dominant species with peak densities in September. The E. pacifica from group W was distributed in the bottom cold water during summer when a thermocline was formed. Five euphausiid species occurred in group S. E. pacifica and E. nana were the dominant species. In group S, E. nana was located in the warm and saline Tsushima Warm Current, a branch of the influential Kuroshio Current. Five euphausiid species occurred in group E. E. pacifica and T. longipes were the dominant species. In group E, E. pacifica and T. longipes were distributed in the deep and cold waters, these species prefer low water temperatures and perform vertical migration. The distribution of euphausiids in Korean waters were highly influenced by mass water characteristics, such as temperature and salinity.