• YAKHAK HOEJI
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• v.42 no.1
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• pp.101-107
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• 1998

The antiparkinsonian agent l-deprenyl, a selective monoamine oxidase (MAO)-B inhibitor, is metabolized in part to l-methamphetamine and l-amphetamine. l< /I>-Deprenyl was evaluated for amphetamine and methamphetamine-like discriminative stimulus effects in rats and its mechanism of action was investigated. Rats were trained under a 5-response, fixed ratio schedule of stimulus-shock termination or a 10-response. Fixed-ratio schedule of food-presentation which discriminate between d-amphetamine (1mg/kg, i.p.) and saline or d-methamphetamine (1mg/kg, i.p.) and saline in a two-lever, operant conditioning procedure. Full generalization was obtained to d-amphetamine (1~3mg/kg). d-methamphetamine (1~3mg/kg) and l-deprenyl (17~30mg/kg) under both the food presentation and stimulus shock termination schedule. l-Deprenyl has dose-dependent amphetamine-and methamphetamine-like discriminative stimulus properties in rats only at doses of 17 and 30mg/kg. Reversible MAO-B inhibitor, RO 16-6491 didn`t show any amphetamine-like discriminative properties. Aromatic amino acid decarboxylase inhibitor, NSD 1015 decreased % responding of l-deprenyl in the methamphetamine-trained rats under the stimulus-shock termination schedule. SKF-525A produced partial inhibition of methamphetamine-like discriminative effects of l-deprenyl under the food presentation schedule. These results suggest that l-deprenyl has no abuse liability at the therapeutic range but there needs some caution at high doses and furthermore, drug discrimination studies under the food presentation and shock termination schedule are useful for the assessment of abuse liability of psychostimulants.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1294-1300
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• 2013

The purpose of this study is to increase contrast to noise ratio(CNR) in myocardial viability test by using contrast agent which highly content gadolinium(1mmol/mL) maximizing diagnostic value. This research method that four hundred four patients were underwent the MRI scanning two hundred eighty four of them were injected commercial contrast media which have 0.5mmol/L and the rest of them were injected new contrast media(gadobutrol) which have 1mmol/mL of molarity to study the contrast difference depending on the molarity of the contrast agent signal intensities of normal ventricle and left ventricle were measured to compare and evaluate signal to noise ratio(SNR) and CNR of the images. As result, 1mmol/mL contrast agent showed higher SNR by 25.13% in myocardium and 30.74% in left ventricle. CNR was proved to be better in 1mmol/mL contrast agent by 31.29%. The results above were all statistically meaningful. Therefore, contrast agent contenting more gadolinium which was 1mmol/mL in this study, could more effectively shorten T1 relaxation time, increase the signal intensity and at the same time maximize CNR and diagnostic value. This study firstly report the usefulness of 1mmol/mL contrast agent in patients allegedly suffering cardiac diseases and it is considered to increase diagnostic value.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.4
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• pp.321-328
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• 2021

This paper derives numerically new buckling Knockdown factors for the lightweight design of the composite propellant tanks for space launch vehicles. A nonlinear finite element analysis code, ABAQUS, is used for the present postbuckling analysis of composite cylinders under compressive loads. Various thickness ratios (R/t) and slenderness ratios (L/R) are considered and Single Perturbation Load Approach is applied to represent the geometric initial imperfection of the composite cylinder. For the composite cylinder with thickness ratio of 500 and slenderness ratio of 2.04, the buckling Knockdown factor derived in this work is higher by 84.38% than NASA's previous buckling design criteria. Therefore, it is investigated that a lightweight design is possible when the present Knockdown factors are used for the design of composite propellant tanks. In addition, it is shown that global buckling loads and buckling Knockdown factors decrease as the thickness ratio or slenderness ratio of composite cylinders increases.

• Journal of Korea Association of Health Promotion
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• v.4 no.1
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• pp.75-84
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• 2006

Background : Osteoporosis and atrophic cell pattern in Pap smear are frequent findings In postmenopausal women due to loss of ovarian function, The present study attempted to find out possible correlation between morphologic characteristics of Pap smear and osteoporosis. Material & methods: The subjects were 825 women(age from 35 to 80) who had undergone Pap smear and bone mineral density(BMD) at The Korea Association of Health Promotion, Seoul Branch, from March 8 to May 10, 2005. Pap smears from 825 women were reviewed and classified either mature cell pattern or atrophic cell pattern by their cytologic patterns, BMD were measured using LUNAR DPX MdIQ(Minster, Ohio, USA). BMD value of lumbar spine(Ll, L2,L3 and L4) were measured from 825 women and BMD value of proximal region off emur(neck NK, Wards triangle WT, and trochanter TR) were measured from 818 women and their bone status were classified as normal( T-sore:>-1.0), osteopenia (T-score: -l~<-2,5) and osteoporosis(T-score: ≤ -2.5). And age distribution of Pap smear, average T-value andfrequency ofsteoporo-sis of each region of the bone, percentage of osteoporosis of each boneregion by age group and changing pattern of percentage of osteopenia and osteoporosis in certain postmenopausal period were compared between mature and atrophic cell pattern. Results: Pap smears revealed total mature cell pattern 53,9%(445/825) and total atrophic cell pattern 46.1%(380/825), Percentage of mature cell pattern decreased from 98.2%(168/171)under 44 age group to 13,3%(17/128) over 65 age group and mature cell pattern increased from 1.8%(3/171) under 44 age group to 86.7%(111/128) oyer 65 age group. Mean T-value of each region of lumbar spine and femur of mature cell pattern were lower than that of atrophic cell pattern about -1,5. And osteoporosis has noted in atrophic cell pattern showing odds ratio Ll 13.9, L2 15.3, L3 12.0, L4 10,4, UK 6.7, WT 10.9 and TR 4.1.Atrophic cell pattern started to increase after 45 years of age and osteoporosis of a trophic cell pattern started after 55 years of age. During 50 to 64 years of age period, L3, L4 and WT revealed parallel increased of osteopenia and osteoporosis and Ll, L2 revealed decreased of osteopenia and increased of osteoporosis. nia Conclusion: Above findings suggest that atrophic cell pattern of Pap smear precedes osteoporosis about 10 years and one of predictor of osteoporosis.

• Steel and Composite Structures
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• v.45 no.1
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• pp.23-38
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• 2022

This paper presents experimental and analytical studies of eccentrically loaded concrete-filled double steel (CFDST) and concrete-filled double skin tube (DCFST) columns having outer stainless steel tube. Eighteen CFDST and DCFST column specimens were manufactured and tested to examine the strength and load-deflection responses. In the study, the main parameters were concrete strength, load eccentricity, cross section and slenderness. The strengths, load-deflection diagrams and failure patterns of the columns were observed. In addition, the tested CFDST and DCFST columns were analyzed to attain the capacity and load versus lateral deflection responses. The obtained theoretical results were compared with the test results. A parametric study was also performed to research the effects of the ratio of eccentricity (e/H_o) slenderness ratio (L/r), H_o/t_o ratio, H_i/t_i ratio and the concrete compressive strength on the behavior of columns. In this work, the obtained results indicated that the ductility and capacity of columns were affected by cross section, concrete strength, steel strength, loading eccentricity and slenderness.

• Journal of Environmental Science International
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• v.30 no.9
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• pp.709-717
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• 2021

This study evaluated the growth, physiological responses and productivity based on the intercropping ratio of cherry tomato (Lycopersicon esculentum L.) with basil (Ocimum basilicum L.). on the rooftops to determine out the efficient ratio in urban agriculture. From April to September 2019, an experiment was conducted on the rooftop of Konkuk University Glocal Campus. Cherry tomato and basil were selected as companion plants for eco-friendly urban agriculture on the rooftops. Each plot was created with a width of 100 cm, length of 100 cm, and height of 25 cm. After installing drainage and waterproof layers from bottom to top, substrate was laid out with a height of 20 cm. Intercropping ratio was consisted of a single tomato plant (TC), 2:1 tomato to basil (T₂B₁), 1:1 tomato to basil (T₁B₁), 1:2 tomato to basil 2 (T₁B₂), and a single basil plant (BC), were conducted using a randomized complete plot design with five treatments and three replication (a total 15 plots). Measurements were divided into growth, physiological responses, and productivity parameters, and detailed items were investigated and analyzed by classifying them into plant height, leaf length, leaf width, number of leaves, root length, root collar caliper, chlorophyll contents, fresh weight, dry weight, number of fruit, fruit caliper, fruit weight, and sugar content. Comparative analyses of cherry tomato with basil plants by intercropping ratio, growth, physiological, and productivity responses are determined to be efficient when the ratio of cherry tomato to basil ratio is 2:1 or 1:1.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.11 no.4
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• pp.610-618
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• 2000

A T-shaped microstripline -fed printed slot antenna is anlayzed by using the transmission line model(TLM) in this paper. Microstrip-slotline junction is modeled by employing a transformer and the transformer turn ratio is derived empirically. The method is extended to the case of $1\times2,l\times4$array antennas. Return loss results obtained by using the transmission line model. The maximum measured results and demonstrated the usefulness of the transmission line model. The maximum bandwidths of a single antenna, $1\times2,l\times4$ array antennas are 28.5%, 47.8%, and 50.9%, respectively, for the VSWR$\leq2$. The gain of $1\times4$ array antenna is 7.97dBi and the beamwidth is about $27^{\circ}$.

• International Journal of Industrial Entomology and Biomaterials
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• v.25 no.2
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• pp.147-151
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• 2012

Fifteen races resulted from silkworm breeding program at Sericulture Research Department (SRD) were used for hybridization. Fourteen hybrids were obtained and coded as; Giza C, D, R, S, T, U, A, V, W, P, H, L and Qanater 1, 2. The traits of cocoon weight, cocoon shell weight, pupal weight, cocoon shell ratio, silk productivity, fifth instar duration, total larval duration, number of cocoon per liter and pupation ratio were evaluated. Data were analyzed by using three formulae of heterosis over better, mid and check parent values. Hybrids of Giza V, C, N, Qanater 1 and 2 are promising and could be used in commercial cocoon production. Generally, there are some new hybrids can be exploited in commercial scale. Also, the local races can be evolved using the hybridization, inbreeding and selection program.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.1163-1164
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• 2006

TZM alloy having elongated coarse-grain structure was developed by three-step internal nitriding treatment at 1423 to 1873 K in $N_2$ and subsequent recrystallization treatment at 2173 K in vacuum. Some specimens were subjected to re-nitriding treatment at 1873 K for 16 h. After the recrystallization treatment, aspect ratio (L/W) of grains for rolling direction was about 50 at the maximum. Yield stress obtained at 1773 K after re-nitriding treatment was about 6 times as large as that of recrystallized specimen. Re-nitriding was very effective in the improvement in strength of TZM alloy having elongated coarse-grain structure.

• Steel and Composite Structures
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• v.9 no.4
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• pp.367-380
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• 2009

This study focuses on the experimental evaluation of the flexural-torsional performance of high strength thin-walled composite members. A series of tests on composite members with various sectional aspect ratios subjected to eccentric cyclic loads were conducted. Test results show that the composite member's torsional strength could be approximated using a series of linear segments and evaluated using the superposition of the component steel and reinforced concrete responses. It is also validated from the tests that the strength deterioration of members subjected to combined loads is closely related to the aspect ratios of the sections. An interaction expression between the bending and torsion for high strength thin-walled composite members is proposed for engineering practice references.