• Title/Summary/Keyword: T/C 계획

Search Result 146, Processing Time 0.028 seconds

Comparative evaluation of dose according to changes in rectal gas volume during radiation therapy for cervical cancer : Phantom Study (자궁경부암 방사선치료 시 직장가스 용적 변화에 따른 선량 비교 평가 - Phantom Study)

  • Choi, So Young;Kim, Tae Won;Kim, Min Su;Song, Heung Kwon;Yoon, In Ha;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.33
    • /
    • pp.89-97
    • /
    • 2021
  • Purpose: The purpose of this study is to compare and evaluate the dose change according to the gas volume variations in the rectum, which was not included in the treatment plan during radiation therapy for cervical cancer. Materials and methods: Static Intensity Modulated Radiation Therapy (S-IMRT) using a 9-field and Volumetric Modulated Arc Therapy (VMAT) using 2 full-arcs were established with treatment planning system on Computed Tomography images of a human phantom. Random gas parameters were included in the Planning Target Volume(PTV) with a maximum change of 2.0 cm in increments of 0.5 cm. Then, the Conformity Index (CI), Homogeneity Index (HI) and PTV Dmax for the target volume were calculated, and the minimum dose (Dmin), mean dose (Dmean) and Maximum Dose (Dmax) were calculated and compared for OAR(organs at risk). For statistical analysis, T-test was performed to obtain a p-value, where the significance level was set to 0.05. Result: The HI coefficients of determination(R2) of S-IMRT and VMAT were 0.9423 and 0.8223, respectively, indicating a relatively clear correlation, and PTV Dmax was found to increase up to 2.8% as the volume of a given gas parameter increased. In case of OAR evaluation, the dose in the bladder did not change with gas volume while a significant dose difference of more than Dmean 700 cGy was confirmed in rectum using both treatment plans at gas volumes of 1.0 cm or more. In all values except for Dmean of bladder, p-value was less than 0.05, confirming a statistically significant difference. Conclusion: In the case of gas generation not considered in the reference treatment plan, as the amount of gas increased, the dose difference at PTV and the dose delivered to the rectum increased. Therefore, during radiation therapy, it is necessary to make efforts to minimize the dose transmission error caused by a large amount of gas volumes in the rectum. Further studies will be necessary to evaluate dose transmission by not only varying the gas volume but also where the gas was located in the treatment field.

Effectiveness Assessment on Jaw-Tracking in Intensity Modulated Radiation Therapy and Volumetric Modulated Arc Therapy for Esophageal Cancer (식도암 세기조절방사선치료와 용적세기조절회전치료에 대한 Jaw-Tracking의 유용성 평가)

  • Oh, Hyeon Taek;Yoo, Soon Mi;Jeon, Soo Dong;Kim, Min Su;Song, Heung Kwon;Yoon, In Ha;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.31 no.1
    • /
    • pp.33-41
    • /
    • 2019
  • Purpose : To evaluate the effectiveness of Jaw-tracking(JT) technique in Intensity-modulated radiation therapy(IMRT) and Volumetric-modulated arc therapy(VMAT) for radiation therapy of esophageal cancer by analyzing volume dose of perimetrical normal organs along with the low-dose volume regions. Materials and Method: A total of 27 patients were selected who received radiation therapy for esophageal cancer with using $VitalBeam^{TM}$(Varian Medical System, U.S.A) in our hospital. Using Eclipse system(Ver. 13.6 Varian, U.S.A), radiation treatment planning was set up with Jaw-tracking technique(JT) and Non-Jaw-tracking technique(NJT), and was conducted for the patients with T-shaped Planning target volume(PTV), including Supraclavicular lymph nodes(SCL). PTV was classified into whether celiac area was included or not to identify the influence on the radiation field. To compare the treatment plans, Organ at risk(OAR) was defined to bilateral lung, heart, and spinal cord and evaluated for Conformity index(CI) and Homogeneity index(HI). Portal dosimetry was performed to verify a clinical application using Electronic portal imaging device(EPID) and Gamma analysis was performed with establishing thresholds of radiation field as a parameter, with various range of 0 %, 5 %, and 10 %. Results: All treatment plans were established on gamma pass rates of 95 % with 3 mm/3 % criteria. For a threshold of 10 %, both JT and NJT passed with rate of more than 95 % and both gamma passing rate decreased more than 1 % in IMRT as the low dose threshold decreased to 5 % and 0 %. For the case of JT in IMRT on PTV without celiac area, $V_5$ and $V_{10}$ of both lung showed a decrease by respectively 8.5 % and 5.3 % in average and up to 14.7 %. A $D_{mean}$ decreased by $72.3{\pm}51cGy$, while there was an increase in radiation dose reduction in PTV including celiac area. A $D_{mean}$ of heart decreased by $68.9{\pm}38.5cGy$ and that of spinal cord decreased by $39.7{\pm}30cGy$. For the case of JT in VMAT, $V_5$ decreased by 2.5 % in average in lungs, and also a little amount in heart and spinal cord. Radiation dose reduction of JT showed an increase when PTV includes celiac area in VMAT. Conclusion: In the radiation treatment planning for esophageal cancer, IMRT showed a significant decrease in $V_5$, and $V_{10}$ of both lungs when applying JT, and dose reduction was greater when the irradiated area in low-dose field is larger. Therefore, IMRT is more advantageous in applying JT than VMAT for radiation therapy of esophageal cancer and can protect the normal organs from MLC leakage and transmitted doses in low-dose field.

Antimicrobial Activity of Florfenicol Against Fish Pathogenic Bacteria and Pharmacokinetics in Blood of Cultured Olive Flounder by Oral Administration (Florfenicol의 어류 병원성 세균에 대한 항균 효과와 경구 투여후 넙치 혈액에서의 약물동태학적 특성)

  • Jung, Sung-Hee;Seo, Jung-Soo
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.25 no.5
    • /
    • pp.1079-1087
    • /
    • 2013
  • The pharmacokinetics of florfenicol (FF) after oral administration was studied in the cultured olive flounder, Paralichthys olivaceus, using high performance liquid chromatography (HPLC). After single administration of FF (20 mg/kg body weight) by oral route in olive flounder ($700{\pm}50$ g, $23{\pm}1.5^{\circ}C$), the concentration in the serum was determined at 1, 5, 10, 15, 24, 30, 50 and 168 h post-dose. The kinetic profile of absorption, distribution and elimination of FF in serum were analyzed fitting to a two-compartment model by WinNonlin program. The area under the concentration-time curve (AUC), maximum concentration ($C_{max}$), time for maximum concentration ($T_{max}$) and elimination time were 22.51 ${\mu}g{\cdot}h/mL$, 0.84 ${\mu}g/mL$, 8.62 h and 447 h, respectively. The results of this study related to dosage and withdrawal times could be used for prescription of FF in field for the treatment of bacterial diseases in olive flounder.

Vulnerability Assessment of Landslide by Heavy Rain to Establish Climate Change Adaptation Plan for Local Governments (지자체 기후변화 적응계획 수립지원을 위한 집중호우에 의한 산사태 취약성 평가)

  • Lee, Dong-kun;Kim, Ho Gul;Baek, Gyoung Hye;Seo, Changwan;Kim, Jaeuk;Song, Changkeun;Yu, Jeong Ah
    • Journal of Climate Change Research
    • /
    • v.3 no.1
    • /
    • pp.39-50
    • /
    • 2012
  • KMA(Korea Meteorological Administration) projected that annual mean temperatures of South Korea will rise $3.8^{\circ}C$ and the annual total precipitation will increase by 17 percent by 2100. Rainfall is concentrated during the summer in South Korea. Thus the risk of landslide by heavy rain is expected to increase. After the landslide of Mt. Umyeon occurred in July 2011, disaster of forest sector is highlighted. Therefore vulnerability assessment of landslide is urgent. However, vulnerability assessment based on local governments was not done yet. In this study, we assess vulnerability of landslide by heavy rain for local governments. We used several scenarios to consider uncertainty of climate change. Through this study, local governments can use the results to establish adaptation plans. Also, the results could be used to decrease vulnerability of landslide.

Geo-Morphological Study of Sand Dune for Railway Project in UAE (UAE 내 철도프로젝트 수행을 위한 사막 사구의 지형학적 특성 연구)

  • Moon, Joon-Shik;Kim, Jae-Young;Lee, Seung-Bok
    • Journal of the Korean Geotechnical Society
    • /
    • v.28 no.9
    • /
    • pp.17-22
    • /
    • 2012
  • Wind blown sand is expected to disrupt the operation of the railway as the presented railway project in this paper consists of large earthworks in extreme topography of the mega dune fields. For successful railway construction in sand dune area, effective mitigation measure is the most important factor to protect the track from wind blown sand. The effective mitigation measure requires an integrated consideration of the earthworks geometry and the direct control measures such as fence system. Basically there's no perfect measure protecting railway track from wind blown sand, and it would be more economical and effective to develop robust, deliberate maintenance program for track and direct control measure on the basis of geo-morphological study. The purpose of this study is to identify the large scale geo-morphological terrains and specific sand dune morphology in the project area in UAE and estimate the direction and migration rate for sand dunes with the local variations in prevailing wind directions by undertaking literature review, and aerial photographs, satellite images, and ground studies.

Gelatinization Properties of Starch Dough with Moisture Content, Heating Temperature and Heating Time (수분함량, 가열온도 및 가열시간에 따른 전분 반죽의 호화특성)

  • Lee, Boo-Yong;Lee, Chang-Ho;Lee, Cherl-Ho
    • Korean Journal of Food Science and Technology
    • /
    • v.27 no.3
    • /
    • pp.428-438
    • /
    • 1995
  • The gelatinization properties of corn and waxy corn starch doughs were examined at various moisture contents, heating temperatures and heating times. The onset temperatures of gelatinization with 1% CMC using Brabender Amylograph were $64^{\circ}C$ for both corn and waxy corn starch. In the gelatinization properties using DSC, onset temperature$(T_o)$, maximum peak temperature$(T_p)$, completion temperature$(T_c)$ and enthalpy of the corn starch were $68.15^{\circ}C,\;74.01^{\circ}C,\;85.65^{\circ}C$ and $3.2\;cal/gram$ respectively. While those of the waxy corn starch were $68.24^{\circ}C,\;75.43^{\circ}C,\;93^{\circ}C$ and $4.2\;cal/gram$ respectively. In enzymatic analysis, when the moisture content increased from 36% to 52% and heating temperature from $60^{\circ}C$ to $100^{\circ}C$, the gelatinization degree of starch dough increased from about 10% to about 62%. The gelatinization degree of waxy corn starch dough was $15{\sim}20%$ higher than that of corn starch dough under the same gelatinization conditions. The regression equations of gelatinization degree (Y) of starch dough in the range of $36{\sim}52%$ moisture content $(X_1)\;60{\sim}100^{\circ}C$ heating temperature $(X_2)\;and\;0{\sim}2.0$ min heating time $(X_3)$ were examined using response surface analysis. The regression equation of corn starch dough was: $Y=28.659+8.638\;X_}+15.675\;X_2+7.770\;X_3-1.620\;{X_1}^2+10.790\;X_1X_2-4.220\;{X_2}^2+0.510\;X_1X_3+1.980\;X_2X_3-6.850\;{X_3}^2\;(R^2=0.9714)$ and that of waxy corn starch dough was: $Y=32.617+12.535\;X_1+20.470\;X_2+8.608\;X_3+4.093\;{X_1}^2+13.550\;X_1X_2-4.467\;{X_2}^2+1.560\;X_1X_3+2.160\;X_2X_3-9.527\;{X_3}^2$\;(R^2=0.9621)$. As the moisture content, heating temperature and heating time increased, the reaction rate constant(k) of gelatinization increased. The greatest reaction rate constant was observed at initial 0.5 min heating time of 1st gelatinization stage. At the heating temperature of $90^{\circ}C$, gelatinization of starch dough was completed almost in the initial 0.5 min heating time. The reaction rate constant of waxy corn starch dough was higher than that of corn starch dough under the same gelatinization conditions. At the 52% moisture content, the regression equation between reaction rate constant(k) and heating temperature(T) for corn starch dough was $log\;k=11.1140-4.1226{\times}10^3(1/T)$ (r=-0.9520) and that of waxy corn starch dough was $log\;k=10.1195-3.7090{\times}10^3(1/T)$ (r=-0.9064).

  • PDF

Factors Related to Quit-Smoking Intention among Out-of-school Youths : Based on the Planned Behavioral Theory (학교 밖 청소년의 금연의도 관련요인: 계획된 행위이론 변수를 중심으로)

  • Yim, So Youn;Park, Min Hee
    • Journal of Korean Public Health Nursing
    • /
    • v.33 no.3
    • /
    • pp.354-363
    • /
    • 2019
  • Purpose: This study was undertaken to identify factors related to quit-smoking intention based on the planned behavior theory among out-of-school youths. Methods: This study was a quantitative research, data were collected during Nov. 1. 2018 to Feb. 28, 2019, study subjects were 189 out-of-school youths in Youth support Center located in A, B, C area city. The data were analyzed using independent sample t-test and one-way ANOVA, Pearson's correlation coefficient, and multiple linear regression. Results: There was a significant differences of quit smoking intention according to age, weekly allowance, participate of antismoking program. There were positive correlations between quit smoking intention and attitude to non-smoking and perceived behavior control. In smoking cessation intention influenced by predictive variable, age, weekly allowance, attitude to non-smoking, and perceived behavior control explain 26.8% smoking cessation intention. Conclusion: We believe that findings from this study will help to develop the specific smoking cessation education program for out-of-school youth's health behaviors.

Effects of Grit in Nursing Students on Self-Directed Learning Ability and Adjustment to College Life (간호대학생의 그릿이 자기주도 학습능력과 대학생활적응에 미치는 영향)

  • Hyo-jin Won
    • Journal of Practical Engineering Education
    • /
    • v.15 no.1
    • /
    • pp.89-95
    • /
    • 2023
  • This study is a descriptive research study to analyze the effects of grit in nursing students on self-directed learning ability and adjustment to university life. Data was collected from 260 nursing students including first and second-year nursing students in Region C University. The data was analyzed to find relationships among grit, self-directed learning ability, and college life adjustment using frequency analysis, descriptive statistics, t-test, ANOVA, and multiple regression analysis. The results showed the subdomains of grit in which grit in nursing students affected self-directed learning ability were consistency of interest (t=2.423, p<.05) and perseverance of effort (t=3.761, p<.001). The explanation power of the regression model was 40.2%, which was a statistically significant result (F=23.609, p<.001). The subdomains of grit in which grit in nursing students affected adjustment to college life were the consistency of interest (t=3.112, p<.001) and perseverance of effort (t=3.930, p<.001). The explanation power of the regression model was 43.2%, which was a statistically significant result (F=30.608, p<.001). These results show that it is necessary to develop educational programs to enhance individual nursing students' grit, self-directed learning ability, and college-life adjustment.

Study on the Intensive Catching Method of Anchovy for Live Bait-III Relation Between Variation of Sea Condition and Catch of Anchovy in the Southern Coast of Korea (활멸치의 집약적 생산수단에 관한 연구 -III)

  • 한영호
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.15 no.1
    • /
    • pp.23-33
    • /
    • 1979
  • This paper was analysed based on the oceanographic and meteorological data complied from 1971 to 1977 for that search relationships among the fluctuation of sea condition and weather condition, and the catch of anchovy. In the year when heat loss from the sea surface in winter was maximum(in 1974, 658 Iy), temperature of midwater in summer was lower 2~4\ulcornerC than normal year. While heat loss was minimum (in1973, 487 Iy), temperature of mid water was higher 2\ulcornerC. When temperature of mid water of southern coast from June to August was higher than normal year, anchovy was caught good deal, but that was lower than normal year was bad fishing. When it had much precipitation (in 1973, 256mm), plankton was checked maximum (12cc) and also the catch of anchovy too (11, OOOm/t). While precipitation was minimum (in 1976, 123mm), plankton (3cc) and anchovy (2, 800m/t) was a litle. If we calcalate heat budget in winter, we can forecast temperature of mid-water in summer of following year. Therefore we may be able to forecast catch anchovy.

  • PDF

A Study on the Flagship Store design element based on the Change of the Customer Behavior - Focused on the kolongsport Flagshipstore - (소비자 행동 경향에 따른 플래그십스토어 계획 요소에 관한 연구 - 코오롱스포츠 플래그십스토어를 중심으로 -)

  • Ahn, Hyun-Jeong
    • Korean Institute of Interior Design Journal
    • /
    • v.20 no.2
    • /
    • pp.72-84
    • /
    • 2011
  • In accordance with an active development, we now enjoy web 2.0 generation centering bilateral participation through the web 1.0 environment mainly providing the offering information and take a step web 3.0 understanding information by itself. The same time of digital technic development, consumption market arrived at market3.0 generation, also passed by market 1.0 and went via market 2.0 based on bilateral participation and understanding. This change have the marketing implement index changed as well. Nowadays, 7C is generalized of making up sensibility, emotion, communication, relationship, customization and interactive built as a major strategy from the day of 3p focused on customer environment, service process and 4P focused on physical quality of product. It isn't that brand and merchandise create life and experience like as past. It is focused on embodiment of a way of life, culture and creative experience from consumers' own. This treatise, therefore, fixes the object as flagship store positively reflecting the change and examine the change of a marketing code element and social factor stimulating customer behavior change. As a condition of this study, It fixes Maslow Motivation Theory as the main index of customer behavior, and 7C as the marketing code. This treatise ultimately studies the index of flagship store discussion based on domestic outdoor brand cases.