• 제목/요약/키워드: T/A-50

검색결과 6,592건 처리시간 0.04초

가스화 조건에서 탄종에 따른 석탄 슬래그 점도 거동 (Viscosity of Coal Slags under Gasification Conditions)

  • 문인식;조철범;오명숙
    • 에너지공학
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    • 제11권2호
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    • pp.149-159
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    • 2002
  • 분류층 가스화기에서 슬래그의 점도 변화는 가스화기 운전조건을 결정하는 중요한 요소이다. 본 논문에서는 국내 가스화 대상탄으로 선정된 9개 탄의 슬래그 점도를 가스화 조건에서 측정하였고 점도 변화에 영향을 미치는 슬래그내의 결정체의 크기와 종류를 관찰하였다. 시료는 고둥기술원 건식 가스화기에서 배출된 슬래그 시료를 사용하였다. 9개탄 중 Alaska Usibelli, Curragh, Drayton, Adaro, Baiduri탄 슬래그는 결정슬래그의 경향을 보여주었고, Datong탄과 Cypurus탄 슬래그는 유리슬래그이였다. 결정슬래그외 경우 $T_{cv}$ +$50^{\circ}C$를, 유리슬래그의 경우 $T_{1000}$poise/+$50^{\circ}C$를 가스화기의 최저운전온도로 정의하였을 때 Denisovsky 탄이 가장 높은 온도를, Drayton탄이 가장 낮은 온도를 필요로 하였다. 모든 슬래그가 가스화기 내화물성분인 C $r_2$ $O_3$를 포함하고 있었고, 132$0^{\circ}C$ 주위에서 $T_{cv}$ 를 갖는 결정슬래그의 경우(Alaska Usibeli, Curragh, Adaro탄) 냉각중에 형성됨을 나타내는 커다란 anorthite이 주 결정상으로 나타나 anorthite의 형성이 점도의 급격한 상승의 원인이 됨을 확인하였다. 또한 기포를 갖고 있는 Denisovsky탄의 경우 기포가 산화철의 환원에 의해 형성됨을 추정할 수 있었다..

Isoquercitrin의 세포 보호 작용과 피부 흡수 증진을 위한 리포좀 제형 연구 (Cellular Protective Effect and Liposome Formulation for Enhanced Transdermal Delivery of Isoquercitrin)

  • 조나래;구현아;박수아;한샛별;박수남
    • 대한화장품학회지
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    • 제38권2호
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    • pp.103-118
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    • 2012
  • 본 연구에서는 $H_2O_2$와 rose bengal로 처리된 HaCaT 세포에 있어서 isoquercitrin의 세포 보호 효과를 조사하였다. Isoquercitrin의 피부 전달시스템으로 에토좀 및 탄성 리포좀을 제조하고 입자크기, 포집효율 및 피부 흡수 증진 능력을 평가하였다. Isoquercitrin은 HaCaT 세포에 대해 50 ${\mu}M$의 농도에서 독성을 나타내지 않았다. 5 mM의 $H_2O_2$ 및 25 ${\mu}M$의 rose bengal로 HaCaT 세포를 처리하였을 때 isoquercitrin은 산화적 손상에 대항하여 농도 의존적(6.25 ~ 50 ${\mu}M$)으로 세포 보호 효과를 나타내었다. 0.03 % Isoquercitrin을 담지한 에토좀의 입자 크기는 222.85 nm, 포집효율은 82.26 %였다. 0.03 % isoquercitrin 함유 에토좀은 제조 후 2주일 동안 안정하였고, 일정한 입자 크기를 유지하였다. 피부 투과 실험 결과 에토좀은 일반 리포좀이나 에탄올 용액에서 보다 우수한 피부 투과능을 보여주었다. 0.1 % Isoquercitrin을 담지한 탄성 리포좀의 최적의 제형은 입자 크기(341.2 nm), 가변형성(59.89), 포집효율(54.3 %) 및 피부투과능 (초기 적하량 대비 54.4 %) 확인을 통해 인지질 대 계면활성제의 비율이 85 : 15인 제형이 가장 우수한 탄성 리포좀 제형임을 나타내었다.

Influence of Genotype and Haplotype of MDR1 (C3435T, G2677A/T, C1236T) on the Incidence of Breast Cancer - a Case-Control Study in Jordan

  • Abuhaliema, Ali M;Yousef, Al-Motassem F;El-Madany, Nirmeen N;Bulatova, Nailya R;Awwad, Nemah M;Yousef, Muhammad A;Al Majdalawi, Khalil Z
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권1호
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    • pp.261-266
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    • 2016
  • Background: Breast cancer is the leading cause of cancer death among women and the second in humans worldwide. Many published studies have suggested an association between MDR1 polymorphisms and breast cancer risk. Our aim was to study the association between genetic polymorphism of MDR1 at three sites (C3435T, G2677A/T, and C1236T) and their haplotype and the risk of breast cancer in Jordanian females. Materials and Methods: A case-control study involving 150 breast cancer cases and 150 controls was conducted. Controls were age-matched to cases. The polymerase chain reaction/restriction fragment length polymorphism (PCR-RFLP) technique and sequencing were performed to analyse genotypes. Results: The distribution of MDR1 C3435T genotypes differed between cases and controls [cases, CC 45.3%, CT 41.3%, and TT 13.3%; controls, CC 13.4%, CT 43.3%, and TT 30.2%, p < 0.001]. Similarly, the distribution of G2677A/T significantly differed [cases, GG 43.1 %, GT+GA 50.9% and AA+TT 6%; controls, GG 29.6 %, GT+GA 50.9%, and AA+TT 19.4%, p = 0.004]. On the other hand, genotype and allelotype distribution of C1236T was not statistically different between cases and controls (p=0.56 and 0.26, respectively). The CGC haplotype increased the risk to breast cancer by 2.5-fold compared to others, while TGC and TTC haplotypes carried 2.5- and 5-fold lower risk of breast cancer, respectively. Conclusions: Genetic polymorphisms of MDR1 C3435T and G2677A/T, but not C1236T, are associated with increased risk of breast cancer. In addition, CGC, TGC and TTC haplotypes have different impacts on the risk of breast cancer. Future, larger studies are needed to validate these findings.

Hippocampal Sclerosis: Correlation of MR Imaging Findings with Surgical Outcome

  • Yoon Hee Kim;Kee-Hyun Chang;Sun-Won Park;Young Whan Koh;Sang Hyun Lee;In Kyu Yu;Moon Hee Han;Sang Kun Lee;Chun-Kee Chung
    • Korean Journal of Radiology
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    • 제2권2호
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    • pp.63-67
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    • 2001
  • Objective: Atrophy and a high T2 signal of the hippocampus are known to be the principal MR imaging findings of hippocampal sclerosis. The purpose of this study was to determine whether or not individual MRI findings correlate with surgical outcome in patients with this condition. Materials and Methods: Preoperative MR imaging findings in 57 consecutive patients with pathologically-proven hippocampal sclerosis who underwent anterior temporal lobectomy and were followed-up for 24 months or more were retrospectively reviewed, and the results were compared with the postsurgical outcome (Engel classification). The MR images included routine sagittal T1-weighted and axial T2-weighted spin-echo images, and oblique coronal T1-weighted 3D gradient-echo and T2-weighted 2D fast spin-echo images obtained on either a 1.5 T or 1.0 T unit. The images were visually evaluated by two neuroradiologists blinded to the outcome; their focus was the presence or absence of atrophy and a high T2 hippocampal signal. Results: Hippocampal atrophy was seen in 96% of cases (55/57) [100% (53/53) of the good outcome group (Engel class I and II), and 50% (2/4) of the poor outcome group (class III and IV)]. A high T2 hippocampal signal was seen in 61% of cases (35/57) [62% (33/53) of the good outcome group and 50% (2/4) of the poor outcome group]. All 35 patients with a high T2 signal had hippocampal atrophy. 'Normal' hippocampus, as revealed by MR imaging, occurred in 4% of patients (2/57), both of whom showed a poor outcome (Engel class III). The presence or absence of hippocampal atrophy correlated well with surgical outcome (p<0.01). High T2 signal intensity did not, however, significantly correlate with surgical outcome (p>0.05). Conclusion: Compared with a high T2 hippocampal signal, hippocampal atrophy is more common and correlates better with surgical outcome. For the prediction of this, it thus appears to be the more useful indicator.

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비육돈 사료의 영양소 수준이 돈육 품질에 미치는 영향 (Effect of Nutrient Density of Diet on Pork Quility of Finishing Pigs)

  • 이제룡;서종태;정재두;이진우;하영주;이정일;곽석준;이중동
    • Journal of Animal Science and Technology
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    • 제45권6호
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    • pp.1039-1046
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    • 2003
  • 본 시험은 비육돈 사료의 변화가 돈육의 일반성분, 이화학적 특성, 육색, 아미노산 및 지방산 조성에 미치는 영향을 조사하기 위해 실시하였다. 60${\pm}$3kg의 삼원교잡종 240두를 공시하여 비육돈 사료 변화의 영양소 수준에 따라 대조구는 저영양소 사료 ME 2,960kcal/kg, CP 12.25%, Lysine 0.41%, Ca 0.70, T1은 중영양소 사료 ME 3,220kcal/kg, CP 15.50%, Lysine 0.87%, Ca 0.90 및 T2는 고영양소 사료 ME 3,350kcal/kg, CP 17.50%, Lysine 1.08%, Ca 0.90%로 배합한 사료를 66일간 급여하였다. 단백질, 지방 및 수분 함량은 대조구와 처리구간에 유사하였으며, 조회분 함량은 T1 처리구가 대조구와 T2 처리구에 비해 유의적으로 높았다(p〈0.05). 최종 pH$_{u}$는 T2 처리구가 대조구와 T1 처리구에 비해 유의적으로 높았고, 반면 가열감량은 낮게 나타났다(p〈0.05). 필수아미노산인 Threonine, Isoleucine 및 Histidine는 T2 처리구가 대조구에 비해 높은 반면 비필수아미노산인 Proline과 Glycine는 유의적으로 낮았다(p〈0.05). 대조구가 T1 처리구와 T2 처리구에 비해 포화지방산 및 단일불포화지방산 함량은 높은 경향을 보였고 특히, Oleic acid(18:1) 함량은 유의적으로 높았다(p〈0.05). 다가불포화지방산인 linoleic acid(C18:2)와 arachidonic acid(C20:4) 함량은 대조구에 비해 T1 및 T2 처리구가 유의적으로 높았다(p〈0.05). 이상에서 비육돈 사료 변화의 영양소 수준이 높은 T2 사료를 급여했을 때, 이화학적 특성에서 pH$_{u}$가 높고 가열 감량이 낮아 돈육품질이 향상되었으며 일반성분, 아미노산 및 지방산 조성에서도 대조구와 차이를 보였다.

식물을 이용한 오수의 고도처리에 관한 연구 (A Study on the Advanced Treatment of Wastewater by Plants)

  • 이용두;김현희
    • 한국환경과학회지
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    • 제8권1호
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    • pp.75-81
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    • 1999
  • In recent years increasing production and disposal of wastewater have caused an accelerated eutrophication of receiving waters. Therefore, in order to alleviate the detrimental impact of wastewater discharge, there is an increasing demand for removing the main nutrients, nitrogen and phosphorus, as well as the organic content of the waste water prior to disposal. This is effectively achieved by extended conventional treatment technology. However, the working expenses and energy requirements of such advanced treatment systems are rather high. So in a sparsely populated rural community is required development of wastewater treatment system combined with the regional characteristics. In this study, the systems are planted with Reeds and Amaryllis In A.C and estimated purification potential of system. The results obtained are as follows. BOD removal rate is 20% in the early stage, the last removal rate is 35% in A.C process and is 65% in Amaryllis+A.C process and is 50% in Reed+A.C process. T-N removal rate by Amaryllis is average 2.6g/$m^3$ㆍd, T-N removal rate by Reed is average 1.76g/$m^3$ㆍd. T-P removal rate by Amaryllis is average 0.27g/$m^3$ㆍd, T-P removal rate by Reed is average 0.25g/$m^3$ㆍd. BOD removal rate constant with retention time is 1.4494(1/d), T-N removal rate constant is 0.5428(1/d), T-P removal rate constant is 0.5287(1/d).

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알레르기 비염에 관한 임상적 연구 (A clinical study of allergic rhinitis)

  • 채병윤
    • 대한한의학회지
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    • 제21권3호
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    • pp.149-165
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    • 2000
  • As recent developments of Immunology and Nuclear medicine, serum IgE and IgG values are helpful in the diagnosis and evaluation of the therapeutic effects of nasal allergies. But in Korea, air pollution and the increased use of food additives have become leading factors in nasal allergies, It seems to be induced by environmental change, especially industrialization and urbanization, so allergic rhinitis in our environment has changed in accordance with the changes made in the living environment. Therefore this study is attempted in order to observe a clinical analysis which places more importance on allergic rhinitis. We studied 200 patients who had visited Kyunghee Oriental Medical Center with allergic rhinitis from January 1, 1999 to December 31, 1999 The results were as follows: 1. The sex distribution was 114 males(57%) and 86 females(43%). In age distribution, the average age was 25. In males, ages ranged from 3 to 66 years old and the average was 23.81. In females, ages ranged from 4 to 67 years old and the average was 28.57. The peak age was 30~39 years old(24%); under 9 years old and 10~19 years old were each 18%; 20~29 years old was 22%; 40~49 years old was 11 %; over 50 years old 6.5%. The gulf between males and females showed a statistically significant difference(P<0.025). 2. In the age of onset, male' s maximum was 62.5, minimum was 0.25; female s maximum was 59.5, minimum was 0.2. Under 9 years old was the most with 34%(male 24%, female 10%), 10~19 years old was 18%, 20~29 years old was 22.5%, 30~39 years old was 13.50%, over 40 years old was 12%, The gulf between males and females were showed statistically significant difference.(p<0.014) 3. The average duration of the disease was 5.67 years. In male and female, the maximum was 30, the minimum was 0.05; under 5 years old was the most with 62%(male 34.50%, female 27.50%); 6~10 years old was 23%. So, under 10 years old was 85%. There was no statistically significant difference in the duration of disease. 4. Regarding type of residence, 47.50% of patients with allergic rhinitis lived in apartments, 52.50% lived in houses. In males, 29.50% lived in apartments, 27.50% lived in houses. In females, 18% lived in apartments, 25% lived in houses. There was no statistically significant difference in the residence by T-test and chi-test. 5. In the distribution of season, spring is the most with 29.5% of patients, winter 28%, fall 25.5%, and summer 17%. But there was no statistically significant difference. 6. After observing 200 patients with allergic rhinitis, classifying main symptoms into 5 types, sneezing was the main symptom in 177cases(88.50%), nasal obstruction in 176cases(88%), rhinorrhea in 169cases(84.5%), post nasal discharge in 87cases(43.50%), and itching in I04cases(52%). The Cumulus ration is 98.50% and symptoms overlapped with an average 3.57±0.1 times but in an analysis of variance of these symptoms, the gulf between males and females was not recognized as statistically significant by T-test and ANOVA. 7. Patients whose families have allergic diseases account for 90 cases(45%) : 49cases(24.50%) male and 41cases(20.50%) female. There were 4 cases (71.11 %) whose families have allergic rhinitis, 9cases(10%) of asthma, and 7.78% with allergic dermatitis. There were 61 (67.80%) cases of patients whose parents have allergic diseases; cases wherein the patient s child had allergic diseases numbered 13 (14.45%); and cases with a sibling with allergic diseases totalled 16cases (17.80%). There was no statistically significant difference in allergic disease regarding sex, parents, or siblings by chi-test. 8. Blood type: For males, type A is the most common, with 37cases(18.5%), followed by type B with 32cases(16%), type O 28cases(l4%) and type AB 13cases(6.5%). For females, type B is the most common, with 30cases(15%), followed by type O with 23cases(l1.5%), type A with 18cases(9%) and type AB with 13cases(6.5%). There was no statistically significant difference in blood type by chi-test. 9. In the selection of prefered food, most patients prefer cool food, with 98 such cases(49%), tepid food in 54cases(27%) and warm food in 48cases(24%). These showed a statistically significant difference in the selection of prefered food between males and females by chi-test(p<0.009). 10. The state of Past History was classified into II types. chronic hypertrophic rhinitis is the most common with 11cases (18.64%), tonsil and adenoid hypertrophy is 8cases(l3.56%), sinusitis is 6cases(10.17%), nasal septum deviation is 4cases, nasal polyp is 2cases, others are 10cases(l6.95%). No statistically significant difference in past history between males and females was shown, but a statistically significant difference was shown when males and females were compared with total cases by T-test(p<0.002, P<0.0008). 11. Regarding complications, 37 patients (28.91%) had sinusitis: 22cases(17.19%) in male, 15cases(11.72%) in female. Chronic hypertrophic rhinitis was found in 15cases(11.72%). Others are under 10%. There was no statistically significant difference in the type of complications between males and females, but a statistically significant difference was shown when males and females were compared with total cases by T-test(P<0.00l, P<0.007). 12. In the treatment, medication was used 1691 times, an average of 2.58 times. No.34 was used 370 times for 124 cases, an average of 2.98 times. No. 152 was used 318 times for 106 cases, an average of 3.00 times. No.151 was used 307 times for 97cases, an average of 3.16 times. No. 31 was used 117 times for 33 cases, an average of 3.55 times. No 25 was used 116 times for 33 cases, an average of 3.52 times. 13. In the duration of treatment, the most frequent is 1 week(69cases, 34.50%), the maximum is 20weeks, and the minimum is 1week. A treatment period of 2~3 weeks accounted for 32% of cases, a period of 4~5weeks accounted for 13.5%. The gulf between males and females showed a statistically significant difference in the duration of treatment.(p<0.01). There was a statistical significance when the males were compared with total cases by ANOVA(P<0.03). 14. A comparison between before-treatment and after-treatment showed a statistically significant difference in treatment by T-test (p<0.01) and F-test (p<0.0058).

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유도 브릴루앙 산란 위상공액 거울을 이용한 Nd:YAG 레이저 발진기의 출력특성 (Characteristics of the Nd:YAG laser with stimulated brillouin scattering phase conjugate mirror)

  • 이동원;이성구;박승현;공홍진
    • 한국광학회지
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    • 제13권6호
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    • pp.548-553
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    • 2002
  • 유도 브릴루앙 산란 위상공액 거울(SBS-PCM)을 이용한 Nd:YAG 레이저 발진기를 구성하고 특성을 조사하였다. SBS-PCM은 SBS-cell과 렌즈계의 조합으로 구성되어 있다. Q-switcher를 사용하지 않은 경우, SBS-cell이 SBS-PCM으로 작용하지 않은 것을 확인하였고, Cr:YAG(T=50%) Q-switcher가 사용된 경우는 SBS-cell이 SBS-PCM으로 작용하였다. 이 경우 에너지 출력특성은 SBS-PCM의 유무에 관계엾이 차이가 없으나, 출력의 빔프로파일은 크게 향상되었다. 이를 설명하기 위해 초평면에서의 세기에 따른 반사율차이를 이용한 간단한 공간주파수 여과모형을 제시하고 시뮬레이션 하였다.

인체 T-림프구 hprt 유전자에서 방사선 및 pentachlorophenol에 의한 돌연변이 빈도의 비교(I) (Comparison of Mutant Frequencies Induced by ${\gamma}$-radiation and Pentachlorophenol at hprt Locus in Human T-lymphocytes(I))

  • 김인규;박선영;윤병수;조명행;이영순
    • Journal of Radiation Protection and Research
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    • 제22권1호
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    • pp.15-21
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    • 1997
  • 인체 T-림프구에서 감마선과 대표적 화학 독성물질인 pentachlorophenol(PCP)의 돌연변이 효과를 hypoxanthine phosphoribosyl transferase(hprt) 유전자의 돌연변이 빈도로써 측정하였다. 감마선은 $^{137}$Cs원을 사용하여 세포의 초기배양 시기에 0-3.0 Gy를 조사하였고, PCP는 세포의 초기배양시 최종농도 0-100 ppm으로 24시간 투여하였다. 돌연변이세포는 6-thioguanine을 처리 하에 세포가 성장하는 능력으로 분류하였다. 방사선에 의한 돌연변이빈도는 1.0 Gy, 2.0 Gy와 3.0 Gy 선량에서 대조군보다 약40%, 400%와 750% 증가하였고 0.2 Gy와 0.5 Gy의 선량에서는 유의성 있는 변화가 없었다. PCP를 15 ppm, 25 ppm 그리고 50 ppm을 처리하였을 때 대조군보다 각각 30%, 90% 및 520%정도 증가하였다.

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PCR for Diagnosis of Male Trichomonas vaginalis Infection with Chronic Prostatitis and Urethritis

  • Lee, Jong-Jin;Moon, Hong-Sang;Lee, Tchun-Yong;Hwang, Hwan-Sik;Ahn, Myoung-Hee;Ryu, Jae-Sook
    • Parasites, Hosts and Diseases
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    • 제50권2호
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    • pp.157-159
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    • 2012
  • The aim of this study was to assess the usefulness of PCR for diagnosis of Trichomonas vaginalis infection among male patients with chronic recurrent prostatitis and urethritis. Between June 2001 and December 2003, a total of 33 patients visited the Department of Urology, Hanyang University Guri Hospital and were examined for T. vaginalis infection by PCR and culture in TYM medium. For the PCR, we used primers based on a repetitive sequence cloned from T. vaginalis (TV-E650). Voided bladder urine (VB1 and VB3) was sampled from 33 men with symptoms of lower urinary tract infection (urethral charge, residual urine sensation, and frequency). Culture failed to detect any T. vaginalis infection whereas PCR identified 7 cases of trichomoniasis (21.2%). Five of the 7 cases had been diagnosed with prostatitis and 2 with urethritis. PCR for the 5 prostatitis cases yielded a positive 330 bp band from bothVB1 and VB3, whereas positive results were only obtained from VB1 for the 2 urethritis patients. We showed that the PCR method could detect T. vaginalis when there was only 1 T. vaginalis cell per PCR mixture. Our results strongly support the usefulness of PCR on urine samples for detecting T. vaginalis in chronic prostatitis and urethritis patients.