• Title/Summary/Keyword: Systems Engineering(SE)

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Alcohol exposure induces depression-like behavior by decreasing hippocampal neuronal proliferation through inhibition of the BDNF-ERK pathway in gerbils

  • Kim, Ji-Eun;Ji, Eun-Sang;Seo, Jin-Hee;Lee, Moon-Hyoung;Cho, Se-Hyung;KimPak, Young-Mi;Seo, Tae-Beom;Kim, Chang-Ju
    • Animal cells and systems
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    • v.16 no.3
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    • pp.190-197
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    • 2012
  • Depression is one of the most prevalent diseases of alcohol abuse. Brain-derived neurotrophic factor (BDNF) plays a critical role in cell survival in the hippocampus. Phosphorylation of extracellular signal-regulated kinase 1/2 (p-ERK1/2) is induced by BDNF, and it regulates cell proliferation and differentiation in the brain. We investigated the effects of alcohol intake on depression-like behavior, cell proliferation, expressions of BDNF and its downstream molecules in the hippocampus using Mongolian gerbils. The gerbils were divided into four groups: control group, 0.5 g/kg alcohol-treated group, 1 g/kg alcohol-treated group, 2 g/kg alcohol-treated group. Each dose of alcohol was orally administered for 3 weeks. The present results demonstrated that alcohol intake induced depression-like behavior. Both 5-hydroxytryptamine synthesis and its synthesizing enzyme tryptophan hydroxylase expression in the dorsal raphe and cell proliferation in the hippocampal dentate gyrus were decreased by alcohol intake. Alcohol intake suppressed BDNF expression, and resulted in the decrease of its downstream molecules, pERK1/2 and Bcl-2, in the hippocampus. We showed that alcohol intake may lead to a depressed-like state with reduced hippocampal cell proliferation through inhibition of the BDNF-ERK signaling pathway.

Cloud Platform for Smartfarm (스마트팜을 위한 클라우드 플랫폼)

  • Lee, Meong-hun;Yi, Se-yong;Kim, Joon-yong;Yoe, Hyun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.10a
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    • pp.496-499
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    • 2016
  • The smartfarm is a leader in the Field of environmental monitoring in agriculture. By the use of wireless remote systems, monitoring applications of the smartfarm are able to provide vital information to the farmer wherever he may be. Absentee farmers are finding the ease of viewing the application graphs on their mobile phone is providing them with peace of mind. We design system and technical requirements of service for managing and operating smart-farm based on cloud technology. It describes requirements of cloud technology for monitoring, controlling, managing, and operating cloud-based smart farm. Smart farm system and service with cloud platform contains 3 interfaces and 3 services. In addition, smart-farm using cloud platform could have several cases so it should be established and managed in varying way depending on cultivars, its size and type. This paper will focus the industry's attention on the importance of Open/Standard Cloud platform thereby stimulating the smartfarm in agriculture.

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Hydrological observation system deployment for water Water quantity, quality management (수자원 수량, 수질관리를 위한 수문관측시스템 구축방안)

  • Yu, Se-hwan;Jang, Dong-bae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.10a
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    • pp.882-885
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    • 2014
  • The duration and frequency of flooding and not last long, by the time climate change drought. The increased accordingly by reducing stream flow and year variation. This trend is expected to continue, and change towards a comprehensive analysis of such quantity, quality and management of water resources are managed. Flood warning system is called to perform them electronically to the management of water resources such as these to be in the organic water-related basic data acquisition, storage, processing and utilization. Can be divided into hydrological observations and flood warning systems alert system broadcast system. Hydrological observation system is the measurement from the hydrological stations (water level, rainfall, water) that can be observed hydrological status of the dam basin hydrological observation data transmitted to the central office, located at the dam monitoring and control system through a variety of networks including satellite, and the collected defined as the system that sent the K-water head office in 1 minute increments hydrological observation data. Headquartered in support of this decision. Dimensions of the dam are provided in addition to inward. Channeled through various hydrologic analysis and leveraging the data transfer. This paper looks at ways to build out hydrological observation system.

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Information and communication system for integrated management of water resources building measures (수자원 통합관리를 위한 정보통신시스템 구축방안)

  • Yu, Se-Hwan;Jang, Dong-bae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.807-809
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    • 2014
  • Individual dam water management is the comprehensive management of all water-based analyzes, quantity, quality, and comprehensive disaster management as a way to analyze and change. K-water is mainly the four river basins, and multipurpose dams and integrated water management is realized, and such information and communication system for integrated management of water resources is also a user-centered development, dam management, so that you can perform and built electronically be. The information communication system is configured to manage the operation of the control system of the equipment controlling system lower sensor and based on data collected from a field to store information, and to control the remote equipment capabilities. In this paper, the integrated management of water sector bodeung dam Information and Communication System for the best ways to learn about the system's security measures and systems to evaluate for weaknesses.

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A Web application vulnerability scoring framework by categorizing vulnerabilities according to privilege acquisition (취약점의 권한 획득 정도에 따른 웹 애플리케이션 취약성 수치화 프레임워크)

  • Cho, Sung-Young;Yoo, Su-Yeon;Jeon, Sang-Hun;Lim, Chae-Ho;Kim, Se-Hun
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.22 no.3
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    • pp.601-613
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    • 2012
  • It is required to design and implement secure web applications to provide safe web services. For this reason, there are several scoring frameworks to measure vulnerabilities in web applications. However, these frameworks do not classify according to seriousness of vulnerability because these frameworks simply accumulate score of individual factors in a vulnerability. We rate and score vulnerabilities according to probability of privilege acquisition so that we can prioritize vulnerabilities found in web applications. Also, our proposed framework provides a method to score all web applications provided by an organization so that which web applications is the worst secure and should be treated first. Our scoring framework is applied to the data which lists vulnerabilities in web applications found by a web scanner based on crawling, and we show the importance of categorizing vulnerabilities according to privilege acquisition.

Precast Segmental PSC Bridge Columns with Precast Concrete Footings : I. Development and Verification of System (조립식 기초부를 갖는 프리캐스트 세그먼트 PSC 교각 : I. 시스템 개발 및 검증)

  • Kim, Tae-Hoon;Park, Se-Jin;Kim, Young-Jin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.4A
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    • pp.395-405
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    • 2009
  • The purpose of this study was to investigate the performance of precast segmental PSC bridge columns with precast concrete footings. The proposed system can reduce work at a construction site and makes construction periods shorter. The precast concrete footings is intended to support precast segmental PSC bridge columns and provides an alternative to current cast-inplace systems, particularly for areas where reduced construction time is desired. Shortened construction time, in turn, leads to important safety and economic advantages when traffic disruption or rerouting is necessary. A model of precast segmental PSC bridge columns was tested under a constant axial load and a cyclically reversed horizontal load. In the companion paper, the experimental and analytical study for the performance assessment of precast segmental PSC bridge columns with precast concrete footings is performed.

Design of BOG re-liquefaction system of 20,000 m3 liquid hydrogen carrier

  • Byeongchang Byeon;Hwalong You;Dongmin Kim;Keun Tae Lee;Mo Se Kim;Gi Dock Kim;Jung Hun Kim;Sang Yoon Lee;Deuk Yong Koh
    • Progress in Superconductivity and Cryogenics
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    • v.25 no.3
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    • pp.49-55
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    • 2023
  • This paper presents the design of a re-liquefaction system as a BOG (boil-off gas) handling process in liquid hydrogen transport vessels. The total capacity of the re-liquefaction system was assumed to be 3 ton/day, with a BOR (boil-off rate) of 0.2 %/day inside the cargo. The re-liquefaction cycle was devised using the He-Brayton Cycle, incorporating considerations of BOG capacity and operational stability. The primary components of the system, such as compressors, expanders, and heat exchangers, were selected to meet domestically available specifications. Case studies were conducted based on the specifications of the components to determine the optimal design parameters for the re-liquefaction system. This encompassed variables such as helium mass flow rate, the number of compressors, compressor inlet pressure and compression ratio, as well as the quantity and composition of expanders. Additionally, an analysis of exergy destruction and exergy efficiency was carried out for the components within the system. Remarkably, while previous design studies of BOG re-liquefaction systems for liquid hydrogen vessels were confined to theoretical and analytical realms, this research distinguishes itself by accounting for practical implementation through equipment and system design.

Efficient Semi-automatic Annotation System based on Deep Learning

  • Hyunseok Lee;Hwa Hui Shin;Soohoon Maeng;Dae Gwan Kim;Hyojeong Moon
    • IEMEK Journal of Embedded Systems and Applications
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    • v.18 no.6
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    • pp.267-275
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    • 2023
  • This paper presents the development of specialized software for annotating volume-of-interest on 18F-FDG PET/CT images with the goal of facilitating the studies and diagnosis of head and neck cancer (HNC). To achieve an efficient annotation process, we employed the SE-Norm-Residual Layer-based U-Net model. This model exhibited outstanding proficiency to segment cancerous regions within 18F-FDG PET/CT scans of HNC cases. Manual annotation function was also integrated, allowing researchers and clinicians to validate and refine annotations based on dataset characteristics. Workspace has a display with fusion of both PET and CT images, providing enhance user convenience through simultaneous visualization. The performance of deeplearning model was validated using a Hecktor 2021 dataset, and subsequently developed semi-automatic annotation functionalities. We began by performing image preprocessing including resampling, normalization, and co-registration, followed by an evaluation of the deep learning model performance. This model was integrated into the software, serving as an initial automatic segmentation step. Users can manually refine pre-segmented regions to correct false positives and false negatives. Annotation images are subsequently saved along with their corresponding 18F-FDG PET/CT fusion images, enabling their application across various domains. In this study, we developed a semi-automatic annotation software designed for efficiently generating annotated lesion images, with applications in HNC research and diagnosis. The findings indicated that this software surpasses conventional tools, particularly in the context of HNC-specific annotation with 18F-FDG PET/CT data. Consequently, developed software offers a robust solution for producing annotated datasets, driving advances in the studies and diagnosis of HNC.

A Development of Monitoring System for Evaluating Factors of Road Serviceability: Road Surface Temperature and Dynamic Loads (도로 공용성 평가를 위한 모니터링 시스템 개발: 노면온도 및 동적 하중)

  • Jo, Eun Se Sang;Jang, Junbong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.44 no.2
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    • pp.237-244
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    • 2024
  • Pavement management systems (PMS) provide procedures to quantify road serviceability based on pavement conditions such as cracks and plastic deformation and suggest proper maintenance methods. The deterioration of the road pavement is relevant to the time although the quantifications on road serviceability in PMS present road surface conditions at the evaluation. More systematic evaluation on road serviceability may need time-dependent factors of road environments and that can improve PMS. Rainfall, temperature and vehicle loads can be environmental factors for road serviceability evaluation. As no data are avablie that can link between road conditions and environmental road factors, we conducted experiments to suggest economical devices and methods to obtain relevant data. We used temperature sensors and accelerometers with Arduino to measure road surface temperature and dynamic loads and provide data to improve pavement serviceability evaluation.

Development of KML conversion technology for ENCs application (전자해도 활용을 위한 KML 변환기술 개발)

  • Oh, Se-Woong;Ko, Hyun-Joo;Park, Jong-Min;Lee, Moon-Jin
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2010.04a
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    • pp.135-138
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    • 2010
  • IMO adopt the revision of SOLAS convention on requirement systems for ECDIS and considered an ECDIS as the major system for E-Navigation strategy on marine transportation safety and environment protection. ENC(Electronic Navigational Chart) as base map of ECDIS is considered as a principal information infrastructure that is essential for navigation tasks. But ENCs are not easy to utilize because they are encoded according to ISO/IEC 8211 file format, and ENCs is required to utilize in parts of Marine GIS and various marine application because they are used for navigational purpose mainly. Meanwhile Google earth is satellite map that Google company service, is utilized in all kinds of industry generally providing local information including satellite image, map, topography, 3D building information, etc. In this paper, we developed KML conversion technology for ENC application. details of development contents consist of ENC loading module and KML conversion module. Also, we applied this conversion technology to Korea ENC and evaluated the results.

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