• Toxicological Research
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• 제30권2호
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• pp.65-70
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• 2014

Recent episodes of severe air pollution in eastern Asia have been reported in the scientific literature and news media. Therefore, there is growing concern about the systemic effects of air pollution on human health. Along with the other well-known harmful effects of air pollution, recently, several animal models have provided strong evidence that air pollutants can induce liver toxicity and act to accelerate liver inflammation and steatosis. This review briefly describes examples where exposure to air pollutants was involved in liver toxicity, focusing on how particulate matter (PM) or carbon black (CB) may be translocated from lung to liver and what liver diseases are closely associated with these air pollutants.

• Journal of Chest Surgery
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• 제33권7호
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• pp.590-593
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• 2000

원발성 페평활근육종은 원발성 폐종양으로써 매우 드문 질환으로 대부분 기관지나 혈관들의 평활근에서 기시하나 드물게는 말초부에서도 생긴다고 한다. 이 드문 종양은 기관지종양과 유사하며, 국소적 혹은 전신적인 증상을 보인다고 하며, 관례적인 흉부방사선검사상 우연히 발견되기도 한다. 본원의 경우 61세의 남자환자에서 우연히 흉부방사선 검사상에 좌측 폐 말초부에서 발견된 큰 종괴가 발견되어 좌 전폐절제술을 시행하였으며, 이의 조직검사상 원발성 폐 평활근육종으로 술후 경과는 양호하였다.

• Tuberculosis and Respiratory Diseases
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• 제52권5호
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• pp.550-556
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• 2002

Microscopic polyangiitis is a systemic small-vessel vasculitis that is associated primarily with necrotizing glomerulonephritis and pulmonary capillaritis. A recurrent and diffuse alveolar hemorrhage due to pulmonary capillaritis is the main clinical manifestation of lung involvement. Recently, and interstitial lung disease that mimics idiopathic pulmonary fibrosis was reported to be rarely associated with microscopic polyangiitis. Here we report two patients with microscopic polyangiitis who showed a honeycomb lung at the time of the initial diagnosis with a brief review of relevant literature.

• Tuberculosis and Respiratory Diseases
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• 제65권6호
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• pp.527-531
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• 2008

저자들은 복부와 왼쪽 상박 및 손등에 발생한 궤양성피부결절을 주소로 내원하여 폐결핵과 파종성 피부 크립토콕쿠스증이 동시에 진단된 1예를 경험하였기에 이를 보고하는 바이다.

• Journal of Oral Medicine and Pain
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• 제40권2호
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• pp.82-87
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• 2015

Methotrexate (MTX) is a chemotherapeutic agent that is used to treat a host of malignancies. But recently, MTX has also been used as a therapeutic agent for chronic inflammatory disorders such as rheumatoid arthritis, psoriasis, and systemic lupus erythematosus. However, MTX is an antimetabolite that affects rapidly dividing normal cells such as oral mucosal epithelial cells, gastrointestinal epithelial cells, and bone marrow cells-which explains why oral mucositis is often an initial manifestation of MTX toxicity. Because oral lesions are frequently initially presented in dental clinics, dentists should consider the possibility of adverse drug reactions in the differential diagnoses of oral lesions through a meticulous collection of patients' medical histories. In this report, we examine patients who suffered from oral ulcerative lesions upon diagnosis of MTX-induced oral mucositis. Then, we suggest approaches for the diagnosis and treatment of MTX-induced oral mucositis through a review of literature.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제10권1호
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• pp.66-70
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• 2007

저자들은 말초 혈액 호산구수 증가, 반복적인 천식, 고정되지 않은 폐 침윤, 그리고 위장관 출혈 및 혈관외 호산구 침윤을 보인 영아에서 p-ANCA와 c-ANCA의 증가 소견과 스테로이드 사용 후 증상과 검사 소견이 급격히 호전을 반복적으로 보이는 임상 소견을 근거로 진단된 영아기 CSS 1예를 경험하였기에 보고하는 바이다.

• 대한두경부종양학회지
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• 제29권2호
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• pp.83-86
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• 2013

Some clinical diseases, such as granulomatous thyroiditis, tuberculosis, and sarcoidosis can cause granulomatous inflammation in thyroid, and theses have various clinical presentations. Granulomatous thyroiditis is an inflammation of thyroid gland, and may be painful and tender in case of infection, radiation, or trauma. Otherwise, autoimmune conditions, medications, or an idiopathic fibrosis may cause to be a painless thyroididtis. It is self-limited, possibly viral, inflammatory thyroid disorder usually presented with thyroid pain and systemic symptoms. Tuberculosis of the thyroid occurs only rarely and the patient may be asymptomatic. In thyroid sarcoidosis, most common findings are painless, progressive enlargement of the thyroid with normal function. We have experienced a case of chronic granulomatous inflammation of thyroid gland presenting as a painless thyroid nodule and report it with a review of literature.

• Tuberculosis and Respiratory Diseases
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• 제43권5호
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• pp.798-804
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• 1996

Chronic eosinophilic pneumonia is a very rare disorder of unknown etiology characterized by striking systemic and pulmonary manifestations such as fever, weight loss, dyspnea, blood eosinophilia, and fluffy peripheral opacities on chest radiograph. A number of these patients developed asthma before or with the onset of illness. The roentgenographic lesion rapidly resoluted with corticosteroid and recurrence was occasionally occured in the same location. Histopathologic features of chronic eosinophilic pneumonia include dense aggregates of eosinophils, histiocytes, and multinucleated giant cells within alveolar spaces, interstitium, and bronchioles associated with scattered lymphocytes and plasma cells. We report a case of chronic eosinophilic pneumonia diagnosed by clinical, radiographic, and histologic findings with review of the literature.

• 대한골관절종양학회지
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• 제4권2호
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• pp.99-102
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• 1998

Sarcoidosis is a multi systemic granulomatous disease of unknown etiology and pathogenesis. The granulomas are non-caseating, and the organs that are affected most frequently are the lungs, the skin, and the eyes. However it may also involve the liver, spleen, bone, nervous system, and other organs. The diagnosis is based on the identification of noncaseating granuloma in the tissues involved, excluding other granulomatous conditions. The diagnosis of sarcoid joint disease is often made in retrospect and only when the lung or eye is involved. We report a case of sarcoid synovitis in knee joint with review of literature.

• Tuberculosis and Respiratory Diseases
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• 제40권4호
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• pp.436-441
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• 1993

경북대학교병원 호흡기내과에서 1992년 10월 화학약품제조공장에서 누출된 이산화질소의 흡입으로 인하여 급성폐손상을 받은 남자 2예를 치험하였기에 문헌고찰과 함께 보고하였다.