• 제목/요약/키워드: Systemic administration

검색결과 445건 처리시간 0.054초

미용성형의료정보 모바일 플랫폼의 사용확산에 영향을 미치는 요인: 기술수용모델을 기반으로 (Factors Influencing the Use Diffusion of Cosmetic Medical Information Mobile Platform: Based on Technology Acceptance Model)

  • 박유영;부제만
    • 무역학회지
    • /
    • 제45권1호
    • /
    • pp.279-300
    • /
    • 2020
  • The cosmetic medical information mobile platform is evolving into a new channel for searching and obtaining relevant information before using cosmetic medical service. In addition, the medical institutions can facilitate the medical contracts, and take advantage of systemic customer management through the cosmetic medical information mobile platform. Therefore, the paradigm of the cosmetic medical mobile service industry is facing a flow of change through the use diffusion of cosmetic medical information mobile platform. In this study, in order to explore the factors affecting the use diffusion of the cosmetic medical information mobile platform, this study used the research model of the influence of the characteristics of the cosmetic medical information mobile platform on perceived convenience and usefulness, and use diffusion by applying TAM(Technology Acceptance Model). As a result, immediateness, interactivity, and customization in the characteristics of cosmetic medical information mobile platform had positive effects on the perceived convenience. Also, interactivity, customization, and economics had positive impacts on perceived usefulness. In addition, perceived convenience and usefulness had positive effects on the use diffusion. Through this study, the factors influencing the use diffusion of cosmetic medical information mobile platform were actually explored, and the service value of the cosmetic medical information mobile platform were categorized. Future research is expected to contribute to the continuous improvement of quality and expansion of the cosmetic medical service market based on various research.

불소투여 후 배출된 요내 불소농도 변화에 관한 연구 (FLUORIDE CONCENTRATION IN URINE EXCRETED AFTER FLUORIDE ADMINISTRATION)

  • 이보경;김태영;김종철
    • 대한소아치과학회지
    • /
    • 제27권1호
    • /
    • pp.62-69
    • /
    • 2000
  • 국소적으로 사용된 불소의 일부와 전신적으로 사용된 불소는 체내로 유입되어 우식을 예방하는 효과를 가진다. 그러나 적정 수준 이상의 불소가 체내로 유입되면 전신적으로 여러 가지 이상을 일으키는 급성, 만성 불소증과 치아불소증을 일으킬 수 있다. 따라서 최대한의 우식예방 효과를 가지며 부작용을 일으키지 않는 적절한 불소량을 아는 것은 매우 중요하다고 할 수 있다. 이러한 불소의 섭취량을 역추적 할 수 있는 가장 일반적인 방법으로는 체외로 배출되는 요내 불소농도를 측정하는 것을 들수 있다. 따라서 불소투여 후 불소의 체내 잔류시간과 일별 요내 불소농도를 비교하고자, 7명의 성인 남자를 대상으로 서로 다른 용량의 불소보조제-대조군 : 불소를 복용하지 않은 군, 1군 : 불소 1mg 복용군, 2군 불소 : 2mg 복용군, 3군 : 불소 3mg 복용군, 4군 : 불소 4mg 복용군 - 를 복용시킨 후 시간변화에 따른 요내 불소농도를 HMDS를 이용한 확산법과 불소이온전극(Orion, 96-09, U.S.A.)을 사용하여 측정하고 다음과 같은 결과를 얻었다. 1. 대조군 요내 불소농도의 평균값은 0.707ppm, 표준편차는 0.362ppm 이었다. 2. 불소투여 후 첫날 요내 불소농도는 4군(4.076ppm), 3군(2.400ppm), 2군(1.494ppm), 1군(0.362ppm) 순으로 높았다. 둘째날부터 1, 2, 3군에서는 대조군과 비교시 통계적 유의차를 보이지 않았으나 4군에서는 둘째날까지 대조군보다 유의성 있게 높았다(p<0.05). 3. 투여된 불소량의 증가에 따라 요내 불소농도도 증가되어 유지되었는데, 둘째날까지는 유의성 있게 높게 유지되었고 셋째날부터는 대조군과 통계적 유의차를 보이지 않았다.

  • PDF

Acidovorax avenae subsp. avenae에 의한 기장 세균성줄무늬병 (Bacterial Stripe of Proso Millet Caused by Acidovorax avenae subsp. avenae in Korea)

  • 윤영남;정지훈;이영훈;김현주;배순도;최병렬;남민희;이영기
    • 식물병연구
    • /
    • 제18권3호
    • /
    • pp.236-239
    • /
    • 2012
  • 2009년 7월 밀양지역의 농가포장에서 재배된 기장의 잎에 세균성 줄무늬증상이 발생되었다. 병징은 잎과 줄기전신에서 갈색의 괴저줄무늬를 보였으며, 포장전체에서 확인되었다. 이병된 잎에서 분리된 4계통의 세균들은 배양적, 생리 생화학적 특성, Biolog 검정, 16S rRNA 유전자 염기서열분석에 의하여 Acidovorax avenae subsp. avenae로 동정되었다. 또한 담배, 토마토에 접종하여 과민성반응을 확인하였으며, 기장에 접종하여 동일 병반을 확인할 수 있었다. 이상의 연구결과에 의하여 기장에서 Acidovorax avenae subsp. avenae에 의한 세균성줄무늬병을 국내 처음으로 보고한다.

Radiation recall dermatitis triggered by sorafenib after radiation therapy for hepatocellular carcinoma

  • Kim, Gwi Eon;Song, Hee-Sung;Ahn, Ki Jung;Kim, Young Suk
    • Radiation Oncology Journal
    • /
    • 제35권3호
    • /
    • pp.289-294
    • /
    • 2017
  • Sorafenib is widely used for unresectable and metastatic hepatocellular carcinomas. Radiation recall dermatitis (RRD) is an acute inflammatory reaction confined to previously irradiated skin that occurs after the administration of certain drugs. RRD after sorafenib treatment is rare; five cases have been reported thus far. We describe a 44-year-old man irradiated for chest wall bone metastasis from hepatocellular carcinoma. Eight days after radiotherapy completion, systemic therapy for metastatic hepatocellular carcinoma was initiated with sorafenib treatment. Eleven days after starting sorafenib, the patient complained of erythematous rash with pruritus in the chest wall, in a location consistent with the previous radiation field. Sorafenib was continued at the same dose, despite the RRD. The skin reaction subsided over the next 2 weeks without any medical intervention.

냉혈 K 심정지액의 반복사용시 전신적인 영향동물실험 6 (Systemic effects of multidose hypothermic potassium cardioplegia: an experimental study in six dogs)

  • 기노석
    • Journal of Chest Surgery
    • /
    • 제17권4호
    • /
    • pp.587-592
    • /
    • 1984
  • Potassium cardioplegia for myocardial preservation is being used extensively in open heart surgery. This study was designed to investigate the change in serum and urine potassium before, during, after the administration of cold blood potassium cardioplegic solution containing 28-30 mEq/L [28.6\ulcorner.56 mEq/L] of potassium chloride in 6 dogs. Total potassium dose used in the study was 14.9\ulcorner.89 mEq/L [1.2 mEq/Kg]. Mean potassium level in serum was within normal limits. Urinary excretion of potassium decreased during bypass but increased after bypass and eventually exceeded the amount of potassium infused as cold blood potassium cardioplegic solution. While cold blood potassium cardioplegia is a safe and efficient method of myocardial protection, postoperative potassium level must be observed carefully in order to detect obligatory potassium excretion following open heart surgery.

  • PDF

Skin Permeation of Flurbiprofen through Excised Rat Skin from Poloxamer 407 Gel

  • Gil, Hyung-Jun;Lee, Woo-Young;Chi, Sang-Cheol
    • Journal of Pharmaceutical Investigation
    • /
    • 제24권3호spc1호
    • /
    • pp.27-32
    • /
    • 1994
  • In order to reduce systemic side effects following oral administration, flurbiprofen was formulated as transdermal gels consisting of the drug, poloxamer 407 and ethanol in buffer solutions. The effect of formulation variables in the preparation of flurbiprofen gels on skin permeation of the drug was evaluated using Keshary-Chien diffusion cells fitted with excised rat skins. The permeation rate of flurbiprofen through rat skin was directly proportional to initial drug concentration (between 0.1% and 1.0%) in the gel while it was inversely proportional to poloxamer 407 concentration (between 17.5% and 25%). The skin permeation of flurbiprofen was substantially influenced by the gel pH between 3 and 7, exhibiting a maximum at pH 4. The concentration effect of ethanol on the permeation of the drug was negligible in the concentration range of $10{\sim}20%$.

  • PDF

Spinal Epidural Lipomatosis in Korean

  • Yoo, Je Chul;Choi, Jeong Jae;Lee, Dong Woo;Lee, Sang Pyung
    • Journal of Korean Neurosurgical Society
    • /
    • 제55권6호
    • /
    • pp.365-369
    • /
    • 2014
  • Spinal epidural lipomatosis (SEL) is a rare disorder, regarded in literature as a consequence of administration of exogenous steroids, associated with a variety of systemic diseases, endocrinopathies and the Cushing's syndrome. Occasionally, SEL may occur in patients not exposed to steroids or suffering from endocrinopathies, namely, idiopathic SEL. Thus far, case studies of SEL among Korean have been published rather sporadically. We reviewed the clinical features of SEL cases, among Koreans with journal review, including this report of three operated cases. According to this study, there were some differences between Korean and western cases. Koreans had higher incidences of idiopathic SEL, predominant involvement in the lumbar segments, very few thoracic involvement and lower MBI, as opposed to westerners.

공공교통 전동차 안전운행을 위한 RIMS 프로젝트 적용의 성공요인 연구 (A Study on the Successful Factors in the Application of RIMS Project for the Safe Operation of Rolling Stocks in the Public Transportation)

  • 이강원;방연근;손영진
    • 한국철도학회논문집
    • /
    • 제9권5호
    • /
    • pp.555-560
    • /
    • 2006
  • This study finds out and suggests success factors for the application of RIMS project through the case study of Seoul Metro and literature survey. The successful application of RIMS needs expert knowledge and concept of BOM, standardization of maintenance planning, check lists of heavy maintenance inspection, organization structure of rolling stock maintenance offices, material management system of warehousing and the process of parts repairing between offices, connection of material ordering system, problem solving of circular spare parts administration among inspection, maintenance, and material organizational units, systemic serial number management of parts with RFID, daily closing diary connected with work process chart, and sufficient period of RIMS's test run. RIMS contributes to real time management of rolling stock maintenance, transparency of management, reliability of train operation, customer satisfaction, and management innovation.

폐진균증 (Pulmonary Mcosis)

  • 임병화;홍완일;김의윤
    • Journal of Chest Surgery
    • /
    • 제6권1호
    • /
    • pp.29-36
    • /
    • 1973
  • It has been known that the pulmonary mycosis generally results from saphrophytic colonization of pre-existing lung cavities, e.g. , due to pulmonary tuberculosis, abscess, bronchiectasis. or congen-ital cysts. Recently, the authors experienced four cases of the pulmonary mycosis which were all treated surgically, and in our opinion, three of them were considered to arise from secondary saphrophytic colonization of pre-existing tuberculous cavities by serial chest roentgenograms. One of them was actinomycosis which was known as relatively rare pulmonary mycosis, and its clinical experience was previously reported. The purpose of this report is mainly to review our clinical experience and some related literatures with three patients with aspergillosis. Many writers have stressed the sputum culture for aspergillus, immunologic study and serial roentgenographic findings were all important or essential in diagnosing aspergillosis. Surgical resection appears to be the treatment of choice for the mycosis of lung, and systemic administration of effective anti-fungal agents such as amphotericin B for aspergillosis and penicillin for actinomycosis respectively following surgical intervention is usually necessary to eradicate completely.

  • PDF