• Journal of Korean Medical Ki-Gong Academy
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• v.15 no.1
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• pp.71-88
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• 2015

Objects : The purpose of this case study is to report the effect of Su-Gi therapy with Oriental medical treatments on systemic psoriasis. Methods : The subject is a patient with systemic psoriasis. This patient was treated with Oriental medical treatments and Su-Gi therapy. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results : After the treatment, the symptoms of psoriasis were relieved. PASI score of this patient went down from 39.6 to 12.5. Conclusions : This study showed that Su-Gi therapy added with Oriental medical treatment can be an effective choice for systemic psoriasis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.4
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• pp.22-30
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• 2018

Objectives : The aim of this study is to investigate the relationship between chronic low grade inflammation theory, psoriasis, and herbal medicine. Methods : We reviewed recent studies on the relationship between chronic low-grade inflammation, psoriasis, and herbal medicine through Pubmed. Results : The pathological basis for psoriasis is the action of inflammatory mediators by the activation of the immune response, which can be a cause of various cardiovascular, metabolic and psychological symptoms of psoriasis patients, in addition to skin lesions. The herbal medicines improve these inflammatory conditions and improve local lesions through herbal medicine such as Qingdai, which have a strong inhibitory effect on IL-17,22 production. Conclusions : Herbal medicines used in psoriasis are thought to be effective not only for the improvement of local psoriasis lesions through anti-inflammatory effect but also for the improvement of systemic inflammation associated with chronic low grade inflammation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.1
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• pp.91-105
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• 2018

Objectives : The purpose of this study is to report the Sik-yang-seng(食養生) therapy with Korean Medicine and acupuncture on a chronic psoriasis patient who is occurred to latrogenic cushing's syndrome. Methods : The patient who has been diagnosed psoriasis had symptoms with latrogenic Cushing's syndrome. The patient was treated with Sik-yang-seng(食養生) therapy including Korean Medicine and acupuncture. Evaluation was done by PASI score, itching score, statistics and pictures. Results : After treatment, the PASI score of patients with Sik-yang-seng(食養生) therapy including Korean Medicine and acupuncture was 1.8 which means 95.5% improvement. Conclusions : Korean medical treatment performed with Sik-yang-seng(食養生) therapy can help recovery of Biwi(脾胃)function therefore can increase effect of the treatment of psoriasis and latrogenic Cushing's syndrome.

• Korean journal of dermatology
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• v.56 no.9
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• pp.548-551
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• 2018

Biologics are the most advanced treatment for psoriasis. Ustekinumab, one of the biologics for psoriasis, is a human monoclonal antibody that binds to the p40 subunit of interleukin-12 and interleukin-23. A 41-year-old woman with a 17-year history of plaque psoriasis and psoriatic arthritis presented with worsening lesions. The patient had previously been treated with a number of topical and systemic medications and narrow band ultraviolet B. However, none of the treatments consistently controlled her disease. Thus, treatment with ustekinumab 45 mg via subcutaneous injection was initiated. Approximately 7 days after the first treatment, she experienced a flare with generalized pustules in her whole body. The condition was controlled with systemic steroid treatment. The patient was subsequently treated with adalimumab, and improvement in her plaque and pustular lesions was noted. Herein, we report a case of psoriasis that flared up after ustekinumab therapy, which was accompanied by a morphological change from plaque to pustular lesions.

• The Journal of Korean Medicine
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• v.31 no.5
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• pp.179-187
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• 2010

There is now growing evidence that psoriasis, like other inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus, is a systemic disorder that is associated with enhanced atherosclerosis and risk of coronary artery disease. Erythrodermic psoriasis is a severe form of psoriasis that can be challenging to treat, and carries with it substantial morbidity and an increased risk of mortality compared with other forms of psoriasis. We experienced a case of an erythrodermic psoriasis patient with heart disease. The patient was suffering from whole body erythema, scale, edema and pain. She was admitted to the hospital, and herbal medication, acupuncture, herbal wet dressing and herbal ointment were applied. After 10 days, her edema and pain were remarkably improved, and the patient was discharged and treated through the outpatient clinic. Almost all symptoms were improved after approximately 3 months. We suggest that herbal medicines can be a choice for severe psoriasis patients and can also be helpful for cardiovascular disease.

• Physical Therapy Korea
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• v.3 no.1
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• pp.73-79
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• 1996

Photochemotherapy(UVA with 8-methoxypsoralen) was given to 30 patients with systemic psoriasis. The results of clearing and long-term(6-month) interval maintenance were reported. Clearing requirements were in general similar to these reported by Melski and Burger. The skin of the 14 patients (46.6%) recovered good skin condition by a once weekly maintenance dose. This result was better than that reported by other authors. 1. During initial treatment period, average number of treatment was 27.3 and average duration treatment was 24.8 weeks. 2. The factors to quit treatment were motion decrease, moving to the remote area, complications, etc. 3. Number of patient who received maintenance treatment was 14. 4. The complications reported from the patients were hyperpigmentation, nausea, headache, pruritis, vomiting, gastritis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.251-259
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• 2007

Objective : This study is designed to investigate the effect of Oriental medical therapy on psoriasis. Methods : We applied Aroma ointment to abnormal skin two times a day. For herbal medicine, Bangpungtongsungsan-gami was given. We checked involvement in scaly skin, erythematosus papules and infiltration according to psoriasis area and severity(PASI) Results : After treatment, the patient showed that itching symptoms was disappeared and score of PASI changed from 27 to 0.8 Conclusions : According to the result, Oriental medical therapy and Aroma therapy has a good effect on psoriasis. But further studies are required to definitely prove the effectiveness of Aroma therapy

• CELLMED
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• v.4 no.4
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• pp.23.1-23.8
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• 2014

Psoriasis is a common, chronic, recurrent, immune-mediated inflammatory disorder of skin. Although conventional topical and systemic therapies yield remission for a while, they carry a risk of many side effects that limit the long term use of these agents and the disease recurs generally in a short period of time after cessation of therapy. An increasing number of psoriatic patients are using herbal products as a treatment to control their disease with less side effects. Clinicians should be aware of plants used in psoriasis and side effects related with them. The aim of this article is to review the different herbs used in psoriasis treatment.

• BMB Reports
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• v.47 no.2
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• pp.60-68
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• 2014

Psoriasis is a chronic inflammatory disorder characterized by an erythematous scaly plaque of the skin and is occasionally accompanied by systemic complications. In the psoriatic lesions, an increased number of cytokine-producing dendritic cells and activated T cells are observed, which indicate that psoriasis is a prototype of an immune-mediated dermatosis. During the last decade, emerging studies demonstrate novel roles for the dendritic cell subsets in the process of disease initiation and maintenance of psoriasis. In addition, recently discovered anti-psoriatic therapies, which specifically target inflammatory cytokines produced by lesional dendritic cells, bring much better clinical improvement compared to conventional treatments. These new therapies implicate the crucial importance of dendritic cells in psoriasis pathogenesis. This review will summarize and discuss the dendritic cell subsets of the human skin and their pathophysiological involvement in psoriasis based on mouse- and patient-oriented studies.

• Herbal Formula Science
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• v.29 no.4
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• pp.311-319
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• 2021

Objectives: The aim of this study is to present one case report on the treatment of psoriasis. Methods: We did retrospective study for one psoriasis patient who had been treated by herbal medicine and acupuncture for more than one year. The patient was treated with Bojungikgi-tang hap Gamisoyo-san, Yukmijihuang-tang hap Gamisoyo-san, Saengmaek-san hap Gamisoyo-san, Gamisoyo-san hap Samul-tang and Gamisoyo-san hap Yukmijihwang-tang. Evaluation was done by PASI score and pictures. Results: After the treatment, the patient showed improvements in PASI. PASI of the patient changed from 28.2 to 0. Conclusions: This study suggests the clinical use of Korean medical treatment in systemic psoriasis.