• Title/Summary/Keyword: System Optimization

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Evaluation of Approximate Exposure to Low-dose Ionizing Radiation from Medical Images using a Computed Radiography (CR) System (전산화 방사선촬영(CR) 시스템을 이용한 근사적 의료 피폭 선량 평가)

  • Yu, Minsun;Lee, Jaeseung;Im, Inchul
    • Journal of the Korean Society of Radiology
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    • v.6 no.6
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    • pp.455-464
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    • 2012
  • This study suggested evaluation of approximately exposure to low-dose ionization radiation from medical images using a computed radiography (CR) system in standard X-ray examination and experimental model can compare diagnostic reference level (DRL) will suggest on optimization condition of guard about medical radiation of low dose space. Entrance surface dose (ESD) cross-measuring by standard dosimeter and optically stimulated luminescence dosimeters (OSLDs) in experiment condition about tube voltage and current of X-ray generator. Also, Hounsfield unit (HU) scale measured about each experiment condition in CR system and after character relationship table and graph tabulate about ESD and HU scale, approximately radiation dose about head, neck, thoracic, abdomen, and pelvis draw a measurement. In result measuring head, neck, thoracic, abdomen, and pelvis, average of ESD is 2.10, 2.01, 1.13, 2.97, and 1.95 mGy, respectively. HU scale is $3,276{\pm}3.72$, $3,217{\pm}2.93$, $2,768{\pm}3.13$, $3,782{\pm}5.19$, and $2,318{\pm}4.64$, respectively, in CR image. At this moment, using characteristic relationship table and graph, ESD measured approximately 2.16, 2.06, 1.19, 3.05, and 2.07 mGy, respectively. Average error of measuring value and ESD measured approximately smaller than 3%, this have credibility cover all the bases radiology area of measurement 5%. In its final analysis, this study suggest new experimental model approximately can assess radiation dose of patient in standard X-ray examination and can apply to CR examination, digital radiography and even film-cassette system.

A study on the feasibility evaluation technique of urban utility tunnel by using quantitative indexes evaluation and benefit·cost analysis (정량적 지표평가와 비용·편익 분석을 활용한 도심지 공동구의 타당성 평가기법 연구)

  • Lee, Seong-Won;Chung, Jee-Seung;Na, Gwi-Tae;Bang, Myung-Seok;Lee, Joung-Bae
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.21 no.1
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    • pp.61-77
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    • 2019
  • If a new utility tunnel is planned for high density existing urban areas in Korea, a rational decision-making process such as the determination of optimum design capacity by using the feasibility evaluation system based on quantitative evaluation indexes and the economic evaluation is needed. Thus, the previous study presented the important weight of individual higher-level indexes (3 items) and sub-indexes (16 items) through a hierarchy analysis (AHP) for quantitative evaluation index items, considering the characteristics of each urban type. In addition, an economic evaluation method was proposed considering 10 benefit items and 8 cost items by adding 3 new items, including the effects of traffic accidents, noise reduction and socio-economic losses, to the existing items for the benefit cost analysis suitable for urban utility tunnels. This study presented a quantitative feasibility evaluation method using the important weight of 16 sub-index items such as the road management sector, public facilities sector and urban environment sector. Afterwards, the results of quantitative feasibility and economic evaluation were compared and analyzed in 123 main road sections of the Seoul. In addition, a comprehensive evaluation method was proposed by the combination of the two evaluation results. The design capacity optimization program, which will be developed by programming the logic of the quantitative feasibility and economic evaluation system presented in this study, will be utilized in the planning and design phases of urban community zones and will ultimately contribute to the vitalization of urban utility tunnels.

Korean Sentence Generation Using Phoneme-Level LSTM Language Model (한국어 음소 단위 LSTM 언어모델을 이용한 문장 생성)

  • Ahn, SungMahn;Chung, Yeojin;Lee, Jaejoon;Yang, Jiheon
    • Journal of Intelligence and Information Systems
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    • v.23 no.2
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    • pp.71-88
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    • 2017
  • Language models were originally developed for speech recognition and language processing. Using a set of example sentences, a language model predicts the next word or character based on sequential input data. N-gram models have been widely used but this model cannot model the correlation between the input units efficiently since it is a probabilistic model which are based on the frequency of each unit in the training set. Recently, as the deep learning algorithm has been developed, a recurrent neural network (RNN) model and a long short-term memory (LSTM) model have been widely used for the neural language model (Ahn, 2016; Kim et al., 2016; Lee et al., 2016). These models can reflect dependency between the objects that are entered sequentially into the model (Gers and Schmidhuber, 2001; Mikolov et al., 2010; Sundermeyer et al., 2012). In order to learning the neural language model, texts need to be decomposed into words or morphemes. Since, however, a training set of sentences includes a huge number of words or morphemes in general, the size of dictionary is very large and so it increases model complexity. In addition, word-level or morpheme-level models are able to generate vocabularies only which are contained in the training set. Furthermore, with highly morphological languages such as Turkish, Hungarian, Russian, Finnish or Korean, morpheme analyzers have more chance to cause errors in decomposition process (Lankinen et al., 2016). Therefore, this paper proposes a phoneme-level language model for Korean language based on LSTM models. A phoneme such as a vowel or a consonant is the smallest unit that comprises Korean texts. We construct the language model using three or four LSTM layers. Each model was trained using Stochastic Gradient Algorithm and more advanced optimization algorithms such as Adagrad, RMSprop, Adadelta, Adam, Adamax, and Nadam. Simulation study was done with Old Testament texts using a deep learning package Keras based the Theano. After pre-processing the texts, the dataset included 74 of unique characters including vowels, consonants, and punctuation marks. Then we constructed an input vector with 20 consecutive characters and an output with a following 21st character. Finally, total 1,023,411 sets of input-output vectors were included in the dataset and we divided them into training, validation, testsets with proportion 70:15:15. All the simulation were conducted on a system equipped with an Intel Xeon CPU (16 cores) and a NVIDIA GeForce GTX 1080 GPU. We compared the loss function evaluated for the validation set, the perplexity evaluated for the test set, and the time to be taken for training each model. As a result, all the optimization algorithms but the stochastic gradient algorithm showed similar validation loss and perplexity, which are clearly superior to those of the stochastic gradient algorithm. The stochastic gradient algorithm took the longest time to be trained for both 3- and 4-LSTM models. On average, the 4-LSTM layer model took 69% longer training time than the 3-LSTM layer model. However, the validation loss and perplexity were not improved significantly or became even worse for specific conditions. On the other hand, when comparing the automatically generated sentences, the 4-LSTM layer model tended to generate the sentences which are closer to the natural language than the 3-LSTM model. Although there were slight differences in the completeness of the generated sentences between the models, the sentence generation performance was quite satisfactory in any simulation conditions: they generated only legitimate Korean letters and the use of postposition and the conjugation of verbs were almost perfect in the sense of grammar. The results of this study are expected to be widely used for the processing of Korean language in the field of language processing and speech recognition, which are the basis of artificial intelligence systems.

Optimization of Solid State Fermentation of Mustard (Brassica campestris) Straw for Production of Animal Feed by White Rot Fungi (Ganoderma lucidum)

  • Misra, A.K.;Mishra, A.S.;Tripathi, M.K.;Prasad, R.;Vaithiyanathan, S.;Jakhmola, R.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.2
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    • pp.208-213
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    • 2007
  • The objective of the experiment was to determine the optimum cultural [moisture levels (55, 60 and 70%), days of fermentation (7, 14 and 21), temperature (25 and $35^{\circ}C$) of incubation)] and nutritional parameters (urea addition (0 and 2%) and variable levels of single super phosphate (0.25 and 0.50% SSP)) for bio-processing of the mustard (Brassica campestris) straw (MS) under solid-state fermentation (SSF) system. The performance of SSF was assessed in terms of favorable changes in cell wall constituents, protein content and in vitro DM digestibility of the MS. Sorghum based inoculum (seed culture) of Ganoderma lucidum to treat the MS was prepared. The 50 g DM of MS taken in autoclavable polypropylene bags was mixed with a pre-calculated amount of water and the particular nutrient in the straw to attained the desired levels of water and nutrient concentration in the substrate. A significant progressive increase in biodegradation of DM (p<0.001), NDF (p<0.01) and ADF (p<0.05) was observed with increasing levels of moisture. Among the cell wall constituents the loss of ADF fraction was greatest compared to that of NDF. The loss of DM increased progressively as the fermentation proceeded and maximum DM losses occurred at 28 days after incubation. The protein content of the treated MS samples increased linearly up to the day $21^{th}$ of the incubation and thereafter declined at day $28^{th}$, whereas the improvement in in vitro DM digestibility were apparent only up to the day $14^{th}$ of the incubation under SSF and there after it declined. The acid detergent lignin (ADL) degradation was slower during the first 7 days of SSF and thereafter increased progressively and maximum ADL losses were observed at the day $28^{th}$ of the SSF. The biodegradation of DM and ADL was not affected by the variation in incubation temperature. Addition of urea was found to have inhibitory effect on fungal growth. The effect of both the levels (0.25 and 0.50) of SSP addition in the substrate, on DM, NDF, ADF, cellulose and ADL biodegradation was similar. Similarly, the protein content and the in vitro DM digestibility remain unaffected affected due to variable levels of the SSP inclusion in the substrate. From the results it may be concluded that the incubation of MS with 60 percent moisture for 21 days at $35^{\circ}C$ with 0.25 percent SSP was most suitable for MS treatment with Ganoderma lucidum. Maximum delignification, enrichment in the protein content and improvement in in vitro DM digestibility were achieved by adopting this protocol of bioprocessing of MS.

Selection of Optimal Variables for Clustering of Seoul using Genetic Algorithm (유전자 알고리즘을 이용한 서울시 군집화 최적 변수 선정)

  • Kim, Hyung Jin;Jung, Jae Hoon;Lee, Jung Bin;Kim, Sang Min;Heo, Joon
    • Journal of Korean Society for Geospatial Information Science
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    • v.22 no.4
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    • pp.175-181
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    • 2014
  • Korean government proposed a new initiative 'government 3.0' with which the administration will open its dataset to the public before requests. City of Seoul is the front runner in disclosure of government data. If we know what kind of attributes are governing factors for any given segmentation, these outcomes can be applied to real world problems of marketing and business strategy, and administrative decision makings. However, with respect to city of Seoul, selection of optimal variables from the open dataset up to several thousands of attributes would require a humongous amount of computation time because it might require a combinatorial optimization while maximizing dissimilarity measures between clusters. In this study, we acquired 718 attribute dataset from Statistics Korea and conducted an analysis to select the most suitable variables, which differentiate Gangnam from other districts, using the Genetic algorithm and Dunn's index. Also, we utilized the Microsoft Azure cloud computing system to speed up the process time. As the result, the optimal 28 variables were finally selected, and the validation result showed that those 28 variables effectively group the Gangnam from other districts using the Ward's minimum variance and K-means algorithm.

Establishment of a NanoBiT-Based Cytosolic Ca2+ Sensor by Optimizing Calmodulin-Binding Motif and Protein Expression Levels

  • Nguyen, Lan Phuong;Nguyen, Huong Thi;Yong, Hyo Jeong;Reyes-Alcaraz, Arfaxad;Lee, Yoo-Na;Park, Hee-Kyung;Na, Yun Hee;Lee, Cheol Soon;Ham, Byung-Joo;Seong, Jae Young;Hwang, Jong-Ik
    • Molecules and Cells
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    • v.43 no.11
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    • pp.909-920
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    • 2020
  • Cytosolic Ca2+ levels ([Ca2+]c) change dynamically in response to inducers, repressors, and physiological conditions, and aberrant [Ca2+]c concentration regulation is associated with cancer, heart failure, and diabetes. Therefore, [Ca2+]c is considered as a good indicator of physiological and pathological cellular responses, and is a crucial biomarker for drug discovery. A genetically encoded calcium indicator (GECI) was recently developed to measure [Ca2+]c in single cells and animal models. GECI have some advantages over chemically synthesized indicators, although they also have some drawbacks such as poor signal-to-noise ratio (SNR), low positive signal, delayed response, artifactual responses due to protein overexpression, and expensive detection equipment. Here, we developed an indicator based on interactions between Ca2+-loaded calmodulin and target proteins, and generated an innovative GECI sensor using split nano-luciferase (Nluc) fragments to detect changes in [Ca2+]c. Stimulation-dependent luciferase activities were optimized by combining large and small subunits of Nluc binary technology (NanoBiT, LgBiT:SmBiT) fusion proteins and regulating the receptor expression levels. We constructed the binary [Ca2+]c sensors using a multicistronic expression system in a single vector linked via the internal ribosome entry site (IRES), and examined the detection efficiencies. Promoter optimization studies indicated that promoter-dependent protein expression levels were crucial to optimize SNR and sensitivity. This novel [Ca2+]c assay has high SNR and sensitivity, is easy to use, suitable for high-throughput assays, and may be useful to detect [Ca2+]c in single cells and animal models.

Tutorial on the Principle of Borehole Deviation Survey - An Application of the Coordinate Transforms (시추공 공곡 측정의 원리 - 좌표계 변환의 응용)

  • Song, Yoonho
    • Geophysics and Geophysical Exploration
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    • v.23 no.4
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    • pp.243-252
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    • 2020
  • To share an understanding of trajectory measurement in surveys using borehole, this tutorial summarizes the relevant mathematical principles of the borehole deviation survey based on coordinate transform. For uncased or open holes, calculations of the azimuth-deviation-tool face rotation using three-component accelerometer and magnetometer measurements are summarized. For the steel-cased holes, calculations are based on the time-derivative formula of the coordinate transform matrix; yaw-pitch-roll angles through time are mathematically determined by integrating the threecomponent angular velocity measurements from the gyroscope while also removing the Earth's rotation effect. Sensor and data fusion to increase the accuracy of borehole deviation survey is explained with an example of the method. These principles of borehole deviation surveys can be adapted for attitude estimation in air-borne surveys or for positioning in tunnels where global positioning system (GPS) signals cannot be accessed. Information on the optimization filter that must be incorporated in sensor fusion is introduced to help future research.

Development of a Simulator for Optimizing Semiconductor Manufacturing Incorporating Internet of Things (사물인터넷을 접목한 반도체 소자 공정 최적화 시뮬레이터 개발)

  • Dang, Hyun Shik;Jo, Dong Hee;Kim, Jong Seo;Jung, Taeho
    • Journal of the Korea Society for Simulation
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    • v.26 no.4
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    • pp.35-41
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    • 2017
  • With the advances in Internet over Things, the demand in diverse electronic devices such as mobile phones and sensors has been rapidly increasing and boosting up the researches on those products. Semiconductor materials, devices, and fabrication processes are becoming more diverse and complicated, which accompanies finding parameters for an optimal fabrication process. In order to find the parameters, a process simulation before fabrication or a real-time process control system during fabrication can be used, but they lack incorporating the feedback from post-fabrication data and compatibility with older equipment. In this research, we have developed an artificial intelligence based simulator, which finds parameters for an optimal process and controls process equipment. In order to apply the control concept to all the equipment in a fabrication sequence, we have developed a prototype for a manipulator which can be installed over an existing buttons and knobs in the equipment and controls the equipment communicating with the AI over the Internet. The AI is based on the deep learning to find process parameters that will produce a device having target electrical characteristics. The proposed simulator can control existing equipment via the Internet to fabricate devices with desired performance and, therefore, it will help engineers to develop new devices efficiently and effectively.

Study on Optimal Design of Traverse Switch System for Maglev Train (자기부상열차용 트레버스 분기기 최적설계 연구)

  • Lee, Younghak;Kim, Chang-Hyun;Lee, Jong-Min
    • Journal of the Korean Society for Railway
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    • v.19 no.6
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    • pp.717-726
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    • 2016
  • Emergency tracks are necessary in case a broken down train evacuates, a train needs to make way for a faster train behind it, or a train suddenly stops and following trains must avoid colliding with it. Magnetic Levitated (maglev) Trains can change track to enter an emergency track using a segmented switch or a traverse switch. On a traverse switch, a train can change its track when the part of the track that the train is on moves to the other track. Currently manufactured Maglev trains have two bodies and the total length is 25 meters. If a traverse switch is used, it will only require 30 meters of track to move the train to the other track, so, when it comes to efficiency of costs and space, the traverse switch surpasses the articulated switch. Therefore, in this paper, an optimized design to secure structural safety and weight lightening is suggested. To achieve these results, the heights of the piled concrete and girders which are both placed on the top of the traverse switch, are set as design variables. The Finite Element Method (FEM), in application of kriging and in the design of the experiments (DOE), is used. Maximum stress, deformation, and structural weight are compared with the results, and through this process structural safety and weight lightening is proven.

A Hardwired Location-Aware Engine based on Weighted Maximum Likelihood Estimation for IoT Network (IoT Network에서 위치 인식을 위한 가중치 방식의 최대우도방법을 이용한 하드웨어 위치인식엔진 개발 연구)

  • Kim, Dong-Sun;Park, Hyun-moon;Hwang, Tae-ho;Won, Tae-ho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.11
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    • pp.32-40
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    • 2016
  • IEEE 802.15.4 is the one of the protocols for radio communication in a personal area network. Because of low cost and low power communication for IoT communication, it requires the highest optimization level in the implementation. Recently, the studies of location aware algorithm based on IEEE802.15.4 standard has been achieved. Location estimation is performed basically in equal consideration of reference node information and blind node information. However, an error is not calculated in this algorithm despite the fact that the coordinates of the estimated location of the blind node include an error. In this paper, we enhanced a conventual maximum likelihood estimation using weighted coefficient and implement the hardwired location aware engine for small code size and low power consumption. On the field test using test-beds, the suggested hardware based location awareness method results better accuracy by 10 percents and reduces both calculation and memory access by 30 percents, which improves the systems power consumption.