• Title/Summary/Keyword: Synthetic method

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A Study on the Types and Causes of Medication Errors and Related Drugs - by Analyzing AJNs Medication Error 73 Cases - (임상에서의 투약오류원인과 관련 의약품 분석 - AJN에 기고된 Medication Error 기사의 73사례를 중심으로 -)

  • Cho Won Sun
    • Journal of Korean Public Health Nursing
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    • v.16 no.1
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    • pp.176-189
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    • 2002
  • The purpose of this study were to illustrate the various medication error types and causes and identified to related drugs to provide basic data for preventing nurses' medication error by analysing 73 cases of AJN 'medication Error' column(1993, Oct -2000, Nov). Nurses' types of medication error were classified into 7 types. The most frequent error types are wrong medication$(21.9\%)$ and the wrong dose$(21.9\%)$ together. The others are wrong $time(4.1\%)$, $omission(2.7\%)$, mechanical $error(2.7\%)$, incorrect IV $rate(1.4\%)$. wrong route $administration(1.4\%)$ in order. Nurses' causes of medication error were 9 kinds. The most frequent type is confusing between similar drug shape, color, size, name, injection devices and patient's $name(43.9\%)$ and the others are lack of knowledge about $drugs(26.8\%),\; slips(7.3\%),\; miscalculating\;dose(4.9\%)$, incorrect adjusts $devices(4.9\%)$, difficulty to read or illegible decimal $point(4.9\%),$ $abbreviation(2.4\%)$, fatigue with $overwork(2.4\%)$ and no communication with $patient(2.4\%)$ in order. Related drugs with medication error are as follows. - dose unit(IU. minims. mcg/min. mEq) : Heparin. insulin. synthetic calcitonin, some enzymes and hormones, vitamins, some antibiotics, tuberculin injection. MgSO4 injection. nitroglycerin - similar size, color and shape drug : $0.9\%$ N/S and acetic acid $0.25\%$ for irrigation. premixed 2mg lidocaine sol. and $0.9\%$ N/S, gentamycin 20mg/2mL for children and 80mg/2mL for adult, dextroamphetamine 5mg and 10mg capsule. sedatives chloral hydrate 250mg/5mL and 500mg/5mL - similar name :Aredia(pamidronate disodium) and Adriamycin(doxorubicin), Lamictal (lamotrigine) and Lamisil 250mg. Elderpryl and enalapril, cefotaxime and cefoxitin, carboplatin and cisplatin, sumatriptan and zolmitriptan, Celebrex and Celexa, Humulin and Humalog, Percodan and Percocet, Diabeta and Diabinese, Epivir and Retrovir, Xanax(alprazolam) and Zantac(ranitidine) - decimal point : low molecular weight warfarin, methotrexate - unfamiliar drug uses of familiar drug ; methotrexate. droperidol, imipramine, propranolol - number of drug name(misleading chemical name) : 6-thioguanine, 6-mercaptopurine, 5-fluorouracil - type of administration route : Oxycodone(OxyContin). - administration time : acarbose(Precose). - injection way (Z-track method): hydroxyzine - epidural cathether : LMWHs(enoxaparin, dalteparin), - ADD Vantage self contained delivery system : ceftriaxone(Rocephin)

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Measurement of GPR Direct Wave Velocity by f-k Analysis and Determination of Dielectric Property by Dispersive Guided Wave (f-k 분석에 의한 레이다파 속도 측정 및 레이다파의 분산성 가이드 현상을 이용한 지하 물성 계산)

  • Yi, Myeong-Jong;Endres, Anthony L.;Kim, Jung-Ho
    • Geophysics and Geophysical Exploration
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    • v.9 no.4
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    • pp.304-315
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    • 2006
  • We have examined the applicability of f-k analysis to the GPR direct wave measurement for water content to characterize vadose zone condition. When the vadose zone consists of a dry surface layer over wet substratum, we obtained f-k spectra where most of the energy is bounded by the air and dry soil velocities. In this case, dry soil velocity was successfully estimated by using high frequency data. On the other hands, when wet soil overlies dry substratum, the f-k spectra show a contrasting response where most of the energy travels with the velocity bounded by dry and wet soil velocities. In this case, the radar waves are trapped and guided within wet soil layer, exhibiting velocity dispersion. By adopting modal propagation theory, we could formulae a simple inversion code to find two layer's dielectric constants as well as layer thickness. By inverting the velocity dispersion curve obtained from f-k spectra of synthetic modeling data, we could obtain good estimates of dielectric constants of each layer as well as first layer thickness. Moreover, we could obtain more accurate results by including the higher mode data. We expect this method will be useful to get the quantitative property of real subsurface when the field condition is similar.

Joint Electromagnetic Inversion with Structure Constraints Using Full-waveform Inversion Result (완전파형역산결과를 구조적 제약 조건으로 이용한 고해상도 전자탐사 복합역산 알고리듬 개발)

  • Jeong, Soocheol;Seol, Soon Jee;Byun, Joongmoo
    • Geophysics and Geophysical Exploration
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    • v.17 no.4
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    • pp.187-201
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    • 2014
  • Compared with the separated inversion of electromagnetic (EM) and seismic data, a joint inversion using both EM and seismic data reduces the uncertainty and gives the opportunity to use the advantage of each data. Seismic fullwaveform inversion allows velocity information with high resolution in complicated subsurface. However, it is an indirect survey which finds the structure containing oil and gas. On the other hand, marine controlled-source EM (mCSEM) inversion can directly indicate the oil and gas using different EM properties of hydrocarbon with marine sediments and cap rocks whereas it has poor resolution than seismic method. In this paper, we have developed a joint EM inversion algorithm using a cross-gradient technique. P-wave velocity structure obtained by full-waveform inversion using plane wave encoding is used as structure constraints to calculate the cross-gradient term in the joint inversion. When the jointinversion algorithm is applied to the synthetic data which are simulated for subsea reservoir exploration, images have been significantly improved over those obtained from separate EM inversion. The results indicate that the developed joint inversion scheme can be applied for detecting reservoir and calculating the accurate oil and gas reserves.

Comparison of GMTI Performance Using DPCA for Various Clutters (DPCA를 이용한 지상 이동 표적 탐지에서 클러터 종류에 따른 성능 비교)

  • Lee, Myung-Jun;Lee, Seung-Jae;Kang, Byung-Soo;Ryu, Bo-Hyun;Lim, Byoung-Gyun;Oh, Tae-Bong;Kim, Kyung-Tae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.28 no.6
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    • pp.487-496
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    • 2017
  • Ground moving target indicator(GMTI) using syntheticaperture radar(SAR) used for finding moving targets on wide background clutter in short time is one of good ways to monitor a traffic situation or an enemy's threat. Although displaced phase center antenna (DPCA) is a real time method with low computational complexity, there have been few studies about its performance against various ground clutters. Thus, we need to analyze GMTI performance for various ground clutters in order to design a suitable DPCA detector. In this paper, simulation results show that the conventional DPCA detector produces different performance in terms of detection rate and false alarm rate. In particular, the false alarm rate of heterogeneous or extremely heterogeneous clutter from urban area is higher than one of homogeneous clutter from natural area.

Study on the simulation of a spark ignition engine using BOOST (상용 소프트웨어를 이용한 스파크 점화 기관의 시뮬레이션에 관한 연구)

  • Jeong, Chang-Sik;Woo, Seok-Keun;Ryu, Soon-Pil;Yoon, Keon-Sik
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.9
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    • pp.733-742
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    • 2016
  • In recent years, gas engines fueled with LNG or synthetic gas have been attracting considerable attention for marine use owing to their potential to facilitate better fuel economy and to reduce emissions. It has been confirmed that gas engines using the Otto cycle, which involves premixed combustion, can satisfy Tier III regulations without the EGR or SCR system. The objective of this study is to acquire simulation technologies for predicting gas engine performances in industrial fields. Using the commercial software BOOST, the simulation is conducted on a gasoline engine rather than a marine engine due to the gasoline engine's easier accessibility. This study consists of two stages. In the first stage published previously, the optimal modeling techniques for representing the behavior of the gas in the intake and exhaust systems were determined. In the current study, we formulated a method to evaluate the combustion and heat transfer processes in the cylinder and to ultimately determine the major performance parameters, given that the analytical model derived from the previous stage has been applied. Through this study, we were able to determine a combustion and heat transfer model and a valve discharge coefficient that are less reliant on empirical data: we were also able to formulate a methodology through which relevant constants are decided. We confirmed that the values of transient cylinder pressure variation, indicated mean effective pressure, and air supply can be successfully predicted using our modeling techniques.

Outdoor Noise Propagation: Geometry Based Algorithm (옥외 소음의 전파: 음 추적 알고리즘)

  • 박지헌;김정태
    • The Journal of the Acoustical Society of Korea
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    • v.21 no.4
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    • pp.339-438
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    • 2002
  • This paper presents a method to simulate noise propagation by a computer for outdoor environment. Sound propagated in 3 dimensional space generates reflected waves whenever it hits boundary surfaces. If a receiver is away from a sound source, it receives multiple sound waves which are reflected from various boundary surfaces in space. The algorithm being developed in this paper is based on a ray sound theory. If we get 3 dimensional geometry input as well as sound sources, we can compute sound effects all over the boundary surfaces. In this paper, we present two approaches to compute sound: the first approach, called forward tracing, traces sounds forwards from sound sources. while the second approach, called geometry based computation, computes possible propagation routes between sources and receivers. We compare two approaches and suggest the geometry based sound computation for outdoor simulation. Also this approach is very efficient in the sense we can save computational time compared to the forward sound tracing. Sound due to impulse-response is governed by physical environments. When a sound source waveform and numerically computed impulse in time is convoluted, the result generates a synthetic sound. This technique can be easily generalized to synthesize realistic stereo sounds for virtual reality, while the simulation result is visualized using VRML.

Studies on the New Analytical Methods for Separation and Recovery of Rare Earth Metals (I) : Adsorption Characteristics of U(VI) Ion by New Synthetic Resins with Macrocyclic Compounds (희토류금속 분리 및 회수를 위한 분석화학적 연구 (제1보) : 우라늄(VI)의 분리회수를 위한 선택이온교환수지 합성과 우라늄(VI) 금속이온의 흡착특성)

  • Jung Oh Jin;Hak Jin Jung;Joon Tea Kim
    • Journal of the Korean Chemical Society
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    • v.32 no.4
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    • pp.358-370
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    • 1988
  • Several new ion exchange resins have been synthesized from chloromethyl styrene-1,4-divinylbenzene(DVB) with 1%, 2%, 4%, and 10%-crosslinking and macrocyclic ligands of cryptand type by interpolymerization method. The adsorption characteristics and the pH, time, solvents and concentration dependence of the adsorption of metal ions by this resin were studied. The correlation between the separation characteristics of uranium, rare earths and transition metal on the resins and the stability constants of complexes with macrocyclic ligands have been examined. The resins were very stable in both acidic and basic media and have good resistance to heat at $280^{\circ}C$. The $UO_2^{+2}$ aqueous solution are not adsorbed on the resins below pH 3.0, but the power of adsorption of $UO_2^{2+}$ increased rapidly above pH 4.0. The optimum equilibrium time for adsorption of metallic ions was twenty minutes and adsorptive power decreased in proportion to crosslinking size of the resins and order of dielectric constants of solvents used and the selective sequence for metal cations is in the order of $UO_2^{2+},\;Cu^{2+}\;and\;Nd^{3+}$.

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Characteristics and Biocompatibility of Electrospun Nanofibers with Poly(L-lactide-co-ε-caprolactone)/Marine Collagen (전기 방사법을 통해 제조된 Poly(L-lactide-co-ε-caprolactone)/Marine Collagen 나노파이버의 특성 및 세포친화력 평가)

  • Kim, Woo-Jin;Shin, Young-Min;Park, Jong-Seok;Gwon, Hui-Jeong;Kim, Yong-Soo;Shin, Heung-Soo;Nho, Young-Chang;Lim, Youn-Mook;Chong, Moo-Sang
    • Polymer(Korea)
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    • v.36 no.2
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    • pp.124-130
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    • 2012
  • The uniform nanofibers of poly(L-lactide-$co$-${\varepsilon}$-caprolactone) (PLCL) with different contents of marine collagen (MC) were successfully prepared by electrospinning method. The effects of the major parameters in electrospinning process such as tip to target distance (TTD), voltage, nozzle size and flow rate on the average diameter of the electrospun nanofiber were investigated in generating composite nanofiber. The diameter and morphology of the nanofibers were confirmed by a scanning electron microscopy (SEM). Also, we measured a water contact angle to determine the surface wettability of the nanofibers. The average diameter of the nanofibers decreased as the value of TTD, MC contents, and voltages increased in comparison with that of pristine PLCL nanofiber. In contrast, the diameter of the nanofibers increased as the flow rate and inner diameter of nozzle increased in comparison with that of pristine PLCL. In addition, the hydrophilicity of the nanofiber and attachment of MG-63 cells on the sheets increased as incorporated collagen contents increased. Therefore, the marine collagen would be a potential material to enhance cellular interactivity of synthetic materials by mimicking the natural tissue.

Synthesis of Cyclododecatriene from 1,3-Butadiene by Trimerization over Amine-Titanium Complex Catalyst (아민-티타늄착체 촉매상에서 1,3-부타디엔의 삼량화반응에 의한 싸이클로도데카트리엔의 합성)

  • Park, Da Min;Kim, Gye-Ryeong;Lee, Ju Hyun;Cho, Deuk Hee;Kim, Geon-Joong
    • Korean Chemical Engineering Research
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    • v.51 no.3
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    • pp.394-402
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    • 2013
  • The new complex catalysts were synthesized by the reaction of titanium compounds (titanium chloride or titanium butoxide) and diamines in this work, and they showed very high catalytic activities for the cyclododecatriene (CDT) synthesis from 1,3-butadiene through trimerization. CDT synthetic reaction was performed in an autoclave reactor, and the effects of reaction temperature, type of catalyst, catalyst amount added into the system, the mole ratio of Al/Ti and immobilization method were investigated on the yield of product CDT. The titanium complex catalyst combined to diamine with 1:1 ratio showed high selectivity to CDT more than 90%. The ratio of TTT-CDT/TTC-CDT isomers in the product revealed as different values, depending on the type of diamine combined to titanium and Ti/diamine ratios. Those homogeneous complexes could be used as a heterogenized catalyst after anchoring on the supports, and the immobilized titanium catalyst retained the catalytic activities for several times in the recycled reactions without leaching. The carbon support containing titanium has exhibited superior activity to the silica support. Especially, when the titanium complex was anchored on the support which was fabricated by the hydrolysis of tripropylaminosilane itself, the resulting titanium catalyst showed the highest BD conversion and CDT selectivity.

Analysis on Spectral Regrowth of Bandwidth Expansion Module by Quadrature Modulation Error in Digital Chirp Generator (디지털 첩 발생기에서의 직교 변조 오차에 의한 대역 확장 모듈에서의 스펙트럴 재성장 분석)

  • Kim, Se-Young;Sung, Jin-Bong;Lee, Jong-Hwan;Yi, Dong-Woo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.7
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    • pp.761-768
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    • 2010
  • This paper presents an effective method to achieve the wideband waveform for high resolution SAR(Synthetic Aperture Radar) using the frequency multiplication technique. And also this paper analyzes the root causes for the spectral regrowth due to 3rd-order intermodulation in chirp bandwidth expansion scheme using quadrature modulator and frequency multipliers. The amplitude and phase imbalance requirement are defined based on the simulation results in terms of quadrature channel imbalance. This minimizes the degradation of range resolution, peak sidelobe ratio and integrated sidelobe ratio. The wideband chirp generator using the frequency multiplier and memory map scheme was manufactured and the compensation technique was presented to reduce the spectral regrowth of SAR waveform by minimizing the amplitude and phase imbalance. After I and Q channel imbalance adjustment, the carrier level reduces -28.7 dBm to -53.4 dBm. Chirp signal with 150 MHz bandwidth at S-band expands to 600 MHz bandwidth at X-band. The sidelobe levels are reduced by about 8 to 9 dB by compensating the amplitude balance between I and Q channels.