• Title/Summary/Keyword: Synthetic Application

Search Result 730, Processing Time 0.028 seconds

The Safety Evaluation of a Potent Angiogenic Activator, Synthetic Peptide (SFKLRY-NH2) for the Skin Application

  • Kim, Dong-Ha;Lim, Yun-Young;Kim, Hyeong-Mi;Kim, So-Young;Kim, Beom-Joon;Park, Sung-Gil;Lee, Tae-Hoon;Cho, Soo-Muk
    • Toxicological Research
    • /
    • v.28 no.1
    • /
    • pp.51-56
    • /
    • 2012
  • A novel synthetic hexapeptide (SFKLRY-$NH_2$) that displays angiogenic activity has been identified by positional scanning of a synthetic peptide combinatorial library (PS-SPCL). This study was carried out to investigate the irritation of the SFKLRY-$NH_2$ on the skin. The tests were performed on the basis of Korea Food and Drug Administration (KFDA) guidelines. In results, cell toxicity is not appeared for SFKLRY-$NH_2$ in HaCaT cells and B16F10 cells. SFKLRY-$NH_2$ induced no skin irritation at low concentration ($10{\mu}m$), mild irritation at high concentration (10mM). We consider that this result is helpful for saying about the safety of SFKLRY-$NH_2$ in clinical use.

Studies on Biodegradation of Synthetic Detergents (합성세제의 성분해에 관한 조사연구)

  • Kwon, Sook-Pyo;Chung, Yong;Sim, Kyl-Soon
    • YAKHAK HOEJI
    • /
    • v.21 no.4
    • /
    • pp.193-199
    • /
    • 1977
  • ABS, Alkyl benzene sulfonate, persists for long periods in stream because of its resistance to biologic degradation. Its bio-degradation is very varied in the environments. This investigation was therefore undertaken in order to know the biodegradation of synthetic detergents which are comprising soft and hard forms from February 1976 to September 1976. The biodegradations by spontaneuos settling and aeration were determined. The reduction rates of ABS, DBS, and LAS were 9.8%, 13.7% and 10.4% by the settlings for 5 days at $25^{\circ}$ and 63.3%, 27.2%, and 43.9% by aeration respectively. It was not contributed effectively to biodegradate the synthetic detergents by the simulaneous incubation with micro-organisms isolated from sewage such as Enterobacter sp., E. coli, Bacillus sp., Flavobacterium sp., Pseudomonas sp., Staphylococcus sp., and etc. Tricking filter could also eliminate some amount of detergent. By the application of this investigation, it could be designed that detergents would be regulated in abuse in context with water pollution and be treated at a proper process in the sewage treatment plant to be installed.

  • PDF

Pullout Performance of Reinforcing Fiber Embedded in Nano Materials Cement Mortar with Nano Clay Contents (나노클레이 첨가량에 따른 나노재료 시멘트 모르타르에 정착된 보강섬유의 인발성능)

  • Oh, Ri-On;Park, Chan Gi
    • Journal of The Korean Society of Agricultural Engineers
    • /
    • v.55 no.3
    • /
    • pp.113-121
    • /
    • 2013
  • Recently, it has been studied for the application of nano-materials in the concrete. Applied a small amount of nano-materials can achieve the goal of high strength, high performance and high durability. The small addition of nano clay improves strength, thermal stability, and durability of concrete because of the excellent dispersion. The present study has investigated the effectiveness, when varying with the contents of nano clay, influencing the pull-out behavior of macro synthetic fibers in nano materials cement mortar. Pullout tests conducted in accordance with the Japan Concrete Institute (JCI) SF-8 standard for fiber-reinforced concrete test methods were used to evaluate the pullout performance of the different nano clay. Nano clay was added to the 0, 1, 2, 3, 4 and 5 % of cement weight. The experimental results demonstrated that the addition of nano clay led to improve the pull-out properties as of the load-displacement curve in the precracked and debonded zone. Also, the compressive strength, flexural strength and pullout performance and of Mix No. 1 and No. 2 increased up to the point when nano clay used increased by 2 and 3 % contents, respectively, but decreased when the exceeded 3 and 4 %, respectively. It was proved by verifying increase of the scratching phenomenon in macro synthetic fiber surface through the microstructure analysis on the surface of macro synthetic fiber.

A Study on Application of Euclid's Geometry at Unit of Equation of Figures in High School 1st Grade (고등학교 도형의 방정식 단원에서 논증기하의 활용에 대한 연구)

  • Kwon, Young-In;Suh, Bo-Euk
    • Communications of Mathematical Education
    • /
    • v.21 no.3
    • /
    • pp.451-466
    • /
    • 2007
  • Geometry in school mathematics is the field that has the possibility of diverse approach such as Synthetic Geometry and Analytic Geometry. Synthetic Geometry is handled in middle schools and Analytic Geometry in the first year of high schools. Therefore, this research show for the possibility of using Synthetic Geometry in high schools which was learned already in middle schools and the way of integrating both of them concretely. This is expected to help students understand the mathematical meaning of figures a lot.

  • PDF

Re-ignition System using Vacuum Triggered Gap-switch for Synthetic Breaking Test

  • Park Seung-Jae;Suh Yoon-Taek;Kim Dae-Won;Kim Maeng-Hyun;Song Won-Pyo;Koh Hee-Seog
    • KIEE International Transactions on Electrophysics and Applications
    • /
    • v.5C no.4
    • /
    • pp.145-151
    • /
    • 2005
  • The synthetic breaking test method was developed to evaluate the breaking performance of ultra high-voltage circuit breaker and made up of two independent circuits; current source circuit and voltage source circuit. In application of this test method, it is necessary to extend the arc of the test breaker. So, the new re-ignition system using VTGS (Vacuum Triggered Gap-Switch) was constructed to improve the efficiency and reliability of this test. In this re-ignition system, VTGS operates in high vacuum state of $5{\time}10^{17}$torr and control system consists of the triggering device and the air M-G (Motor-Generator). This re-ignition system showed the operating characteristics, such as delay time ($t_d$) and jitter time ($t_j$ not exceeding 5us and 1us respectively, and had the operating voltage of $25\~150kVdc$ at the gap distance of 24mm.

A study on the Application of STS wire Mesh air Cleaner for the 2-Wheel Automotive (2륜 자동차 공기청정기의 STS적용에 관한 연구)

  • Yi, C.S.;Lee, Y.H.;Suh, J.S.;Chung, H.S.;Jeong, H.M.
    • Journal of Power System Engineering
    • /
    • v.6 no.4
    • /
    • pp.30-35
    • /
    • 2002
  • This study represents the effects of the material of the air cleaner on the performance in a 4-stroke spark-ignition engine for motorcycles. This study is mainly focused on the possibility of the adopting the STS wire mesh air cleaner of a S.I engine. For investigating the possibility of that, the engine power, the fuel consumption and the exhaust gas analysis were carried out for the synthetic fiber air cleaner and the different size of 200 mesh, 250 mesh, 300 mesh of STS wire mash air cleaner. As the results of this study, the performance of STS wire air cleaner was similar to the fiber air cleaner at 9000 rpm but 300 mesh of STS air cleaner had a high engine power and torque at 9500 rpm. In the case of the synthetic fiber air cleaner the concentration of CO was low at 6500 rpm and in the case of the 300 mesh in STS wire mesh air cleaner the concentration of HC was lowest at all experimental regions.

  • PDF

A Comparative Study on the Multivariate Thomas-Fiering and Matalas Model (다변량 Thomas-Fiering 모형과 Matalas 모형의 비교연구)

  • 이주헌;이은태
    • Water for future
    • /
    • v.24 no.4
    • /
    • pp.59-66
    • /
    • 1991
  • Abstract The purpose of the synthetic of monthly river flows based on the short-term observed data by means of multivariate stochastic models is to provide abundunt input data to the water resources systems of which the system performance and operation policy are to be determined beforehand. In this study, multivariate Thomas-Fiering and Matalas models for synthetic generation based on stream flows in neihboring basin were employed to check if it can be applide in the modeling of monthly flows. Statistical parameters estimated by Method of Moment and Fourier Series Analysis respectively were reproduced for statistical features. For comparisons the statistical parameters of the generated monthly flow by each model were compared with those of the observed monthly flows. Results of this study suggest that the application of Matalas model for synthetic generation of monthly river flows can be adapted.

  • PDF

Machine learning of LWR spent nuclear fuel assembly decay heat measurements

  • Ebiwonjumi, Bamidele;Cherezov, Alexey;Dzianisau, Siarhei;Lee, Deokjung
    • Nuclear Engineering and Technology
    • /
    • v.53 no.11
    • /
    • pp.3563-3579
    • /
    • 2021
  • Measured decay heat data of light water reactor (LWR) spent nuclear fuel (SNF) assemblies are adopted to train machine learning (ML) models. The measured data is available for fuel assemblies irradiated in commercial reactors operated in the United States and Sweden. The data comes from calorimetric measurements of discharged pressurized water reactor (PWR) and boiling water reactor (BWR) fuel assemblies. 91 and 171 measurements of PWR and BWR assembly decay heat data are used, respectively. Due to the small size of the measurement dataset, we propose: (i) to use the method of multiple runs (ii) to generate and use synthetic data, as large dataset which has similar statistical characteristics as the original dataset. Three ML models are developed based on Gaussian process (GP), support vector machines (SVM) and neural networks (NN), with four inputs including the fuel assembly averaged enrichment, assembly averaged burnup, initial heavy metal mass, and cooling time after discharge. The outcomes of this work are (i) development of ML models which predict LWR fuel assembly decay heat from the four inputs (ii) generation and application of synthetic data which improves the performance of the ML models (iii) uncertainty analysis of the ML models and their predictions.

Prediction of concrete spall damage under blast: Neural approach with synthetic data

  • Dauji, Saha
    • Computers and Concrete
    • /
    • v.26 no.6
    • /
    • pp.533-546
    • /
    • 2020
  • The prediction of spall response of reinforced concrete members like columns and slabs have been attempted by earlier researchers with analytical solutions, as well as with empirical models developed from data generated from physical or numerical experiments, with different degrees of success. In this article, compared to the empirical models, more versatile and accurate models are developed based on model-free approach of artificial neural network (ANN). Synthetic data extracted from the results of numerical experiments from literature have been utilized for the purpose of training and testing of the ANN models. For two concrete members, namely, slabs and columns, different sets of ANN models were developed, each of which proved to have definite advantages over the corresponding empirical model reported in literature. In case of slabs, for all three categories of spall, the ANN model results were superior to the empirical models as evaluated by the various performance metrics, such as correlation, root mean square error, mean absolute error, maximum overestimation and maximum underestimation. The ANN models for each category of column spall could handle three variables together: namely, depth, spacing of longitudinal and transverse reinforcement, as contrasted to the empirical models that handled one variable at a time, and at the same time yielded comparable performance. The application of the ANN models for spall prediction of concrete slabs and columns developed in this study has been discussed along with their limitations.

Spatio-temporal soil moisture estimation using water cloud model and Sentinel-1 synthetic aperture radar images (Sentinel-1 SAR 위성영상과 Water Cloud Model을 활용한 시공간 토양수분 산정)

  • Chung, Jeehun;Lee, Yonggwan;Kim, Sehoon;Jang, Wonjin;Kim, Seongjoon
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2022.05a
    • /
    • pp.28-28
    • /
    • 2022
  • 본 연구는 용담댐유역을 포함한 금강 유역 상류 지역을 대상으로 Sentinel-1 SAR (Synthetic Aperture Radar) 위성영상을 기반으로 한 토양수분 산정을 목적으로 하였다. Sentinel-1 영상은 2019년에 대해 12일 간격으로 수집하였고, 영상의 전처리는 SNAP (SentiNel Application Platform)을 활용하여 기하 보정, 방사 보정 및 Speckle 보정을 수행하여 VH (Vertical transmit-Horizontal receive) 및 VV (Vertical transmit-Vertical receive) 편파 후방산란계수로 변환하였다. 토양수분 산정에는 Water Cloud Model (WCM)이 활용되었으며, 모형의 식생 서술자(Vegetation descriptor)는 RVI (Radar Vegetation Index)와 NDVI (Normalized Difference Vegetation Index)를 활용하였다. RVI는 Sentinel-1 영상의 VH 및 VV 편파자료를 이용해 산정하였으며, NDVI는 동기간에 대해 10일 간격으로 수집된 Sentinel-2 MSI (MultiSpectral Instrument) 위성영상을 활용하여 산정하였다. WCM의 검정 및 보정은 한국수자원공사에서 제공하는 10 cm 깊이의 TDR (Time Domain Reflectometry) 센서에서 실측된 6개 지점의 토양수분 자료를 수집하여 수행하였으며, 매개변수의 최적화는 비선형 최소제곱(Non-linear least square) 및 PSO (Particle Swarm Optimization) 알고리즘을 활용하였다. WCM을 통해 산정된 토양수분은 피어슨 상관계수(Pearson's correlation coefficient)와 평균제곱근오차(Root mean square error)를 활용하여 검증을 수행할 예정이다.

  • PDF