• The Transactions of the Korea Information Processing Society
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• v.6 no.6
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• pp.1635-1645
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• 1999

In this paper, an intelligent resynthesis technique for timing optimization at the architecture-level has been studied. The proposed technique can remedy the problem which may occur in combinational timing optimization techniques applied to circuits which have the hierarchical subblock structure at the architectural-level. The approach first tries to maintain the original hierarchical subblock while minimizing the longest delay of whole circuit. This paper tries to find a new approach to timing optimization for circuits which have hierarchical structure at architectural-level, and has verified its effectiveness experimentally. We claim its usefulness from the fact that most designers design the circuits hierarchically due to the increase of design complexity.

• Journal of the Korean Institute of Intelligent Systems
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• v.17 no.2
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• pp.160-166
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• 2007

When a mail was given to users, each user's response could be different according to his or her preference. This paper presents a solution for this situation by constructing a user preferred ontology for anti-spam systems. To define an ontology for describing user behaviors, we applied associative classification mining to study preference information of users and their responses to emails. Generated classification rules can be represented in a formal ontology language. A user preferred ontology can explain why mail is decided to be spam or ron-spam in a meaningful way. We also suggest a new rule optimization procedure inspired from logic synthesis to improve comprehensibility and exclude redundant rules.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2006.11a
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• pp.127-130
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• 2006

Coenzyme Q10(CoQ10) is a biological quinine compound that is widely found in living organisms including yeast, plants, and animals. CoQ10 has two major physiological activities:(a)mitochondrial electron-transport activity and (b )antioxidant activity. Various clinical applications are also available: Parkinson's disease, Heart disease, diabetes. Because of its various application filed, the market size of CoQ10 is continuously expanding all over the world. A Japanese company, Nisshin Pharma Inc. is the first industrial producer of CoQ10(1974). CoQ10 can be produced by fermentation and chemical synthesis. In several companies, these two methods are used for the production of CoQ10:chemical synthesis - Yungjin, Daewoong, Nishin Parma; fermentation - Kaneka, Kyowa, Yungjin, etc. Researchs in microbial production of CoQ10 have several steps: screening of producing microorganisms, strain development, fermentation process, purification process, scale-up process, plant production. Several strategies are available for the strain development : Random mutation and screening, directed metabolic engineering. For the optimization of fermentation process, various conditions (nutrient, aeration, temperature, culture type, etc.) are considered. Purification is one of the most important step because the quality of final products entirely depends on its purity. The production cost will be reduced and the quality of the CoQ10 will be impoved by continuous researches in strain development, fermentation process, purification process.

• Korean Chemical Engineering Research
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• v.56 no.4
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• pp.592-599
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• 2018

An increase in the global production of biodiesel has resulted in the newfound significance of its byproduct, glycerol. The synthesis of acetins is an economical avenue to enhance the value of glycerol derived from biodiesel. WE developed an eco-friendly process for the synthesis of fuel additives from glycerol using a mixed oxide $SO{_4}^{2-}/CeO_2-Al_2O_3$ as catalyst. The $CeO_2-Al_2O_3$ mixed oxide was synthesized by the combustion method and then sulfated. The characterization of the catalyst was by means of XRD, BET, FTIR, and SEM. The influence of temperature, mole ratio and catalyst loading on yield and selectivity of the acetins was studied for the esterification of glycerol. The reaction rate constants ($k_1$, $k_2$ and $k_3$) were estimated using optimization method in MAT lab, and the activation energies ($E_1$, $E_2$ and $E_3$) were determined by the Arrhenius equation. Furthermore, a kinetic model was developed.

• Journal of the Society of Naval Architects of Korea
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• v.35 no.2
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• pp.94-103
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• 1998

Recently, many researches are carried for high-speed and light craft. In this study, the optimum structural design procedure and the computer program are developed to minimize the hull weight of SES(Surface Effect Ship) built of composite materials. Three types of composite materials-Sandwich, Single Skin and Hybrid type- are considered and the efficiency of each type is investigated. In design process, the optimum design of main members is performed at first considering longitudinal strength. And then, the transverse member design is performed considering torsional strength SSDP(Structural Synthesis Design program) of U.S. Navy is adopted for design algorithm and DnV classification nile for design loads and strength criteria. For optimum structural design, ES 1+1 optimization technique is used.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.2 no.1
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• pp.30-36
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• 2003

Recently, mechanically beam-steering microstrip patch array antenna using MEMS technology is developed and tested. In this paper as an application of developed antenna, new radiation pattern synthesis method far beam-steering antenna without phase-shifter is proposed, and applied to synthesis of desired beam shape. Niching genetic algorithm using Restricted Competition Selection (RCS) is used for radiation pattern optimization. This approach can be applied to design of array antenna for meet EMC standard and through proposed method specific beam shapes can be synthesized.

• 한국약용작물학회:학술대회논문집
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• 2006.11a
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• pp.127-130
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• 2006

Coenzyme Q10(CoQ10) is a biological quinine compound that is widely found in living organisms including yeast, plants, and animals. CoQ10 has two major physiological activities:(a)mitochondrial electron-transport activity and (b)antioxidant activity. Various clinical applications are also available : Parkinson's disease, Heart disease, diabetes. Because of its various application filed, the market size of CoQ 10 is continuously expanding all over the world. A Japanese company, Nisshin Pharma Inc. is the first industrial producer of CoQ10(1974). CoQ10 can be produced by fermentation and chemical synthesis. In several companies, these two methods are used for the production of CoQ10:chemical synthesis - Yungjin, Daewoong, Nishin Parma; fermentation - Kaneka, Kyowa, Yungjin, etc. Researchs in microbial production of CoQ10 have several steps: screening of producing microorganisms, strain development, fermentation process, purification process, scale-up process, plant production. Several strategies are available for the strain development : Random mutation and screening, directed metabolic engineering. For the optimization of fermentation process, various conditions (nutrient, aeration, temperature, culture type, etc.) are considered. Purification is one of the most important step because the quality of final products entirely depends on its purity. The production cost will be reduced and the quality of the CoQ10 will be impoved by continuous researches in strain development, fermentation process, purification process.

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.511-516
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• 2005

Sorbitan methacrylate was synthesized from sorbitan dehydrated from D-sorbitol using an immobilized lipase. To optimize the enzymatic synthesis of sorbitan methacrylate, response surface methodology was applied to determine the effects of five-level-four-factors and their reciprocal interactions on sorbitan methacrylate biosynthesis. A total of 30 individual experiments were performed, which were designed to study reaction temperature, reaction time, enzyme amount and substrate molar ratio. A statistical model predicted that the highest conversion yield of sorbitan methacrylate was 100%, at the following optimized reaction conditions: a reaction temperature of 43.06 $^{\circ}C$, a reaction time of 164.25 mins., an enzyme amount of 7.47%, and a substrate molar ratio of 3.98:1. Using these optimal factor values under experimental conditions in four independent replicates, the average conversion yield reached 98.7%${\pm}$1.2% and was well within the value predicted by the model.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.11b
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• pp.194-199
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• 2005

Body-on-frame type vehicle has a set of frame bushes which are installed between body and frame fur vibration Isolation. Such frame bushes are important vibration transmission paths to passenger space. In order to reduce the vibration level of passenger space, therefore, the change of complex stiffness of the frame bushes is more efficient than modification of other parts of the vehicle such as body, frame and suspension. The purpose of this study is to reduce the vibration level for ride comfort by optimization of complex stiffness of frame bushes. In order to do this end, simple finite element vehicle model was constructed and the complex stiffness of frame bushes was set to be design variable. Objective function was defined to reflect passenger ride comfort and genetic algorithm and sub-structure synthesis were applied for minimization of the objective function.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.4
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• pp.17-29
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• 1999

This paper presents a high level synthesis method targeting low power consumption for data-dominated CMOS circuits (e.g., DSP). The high level synthesis is divided into three basic tasks: scheduling, resource and register allocation. For lower power scheduling, we increase the possibility of reusing an input operand of functional units. For a scheduled data flow graph, a compatibility graph for register and resource allocation is formed, and then a special weighted network is then constructed from the compatibility graph and the minimum cost flow algorithm is performed on the network to obtain the minimum power consumption data path assignment. The formulated problem is then solved optimally in polynomial time. This method reduces both the switching activity and the capacitance in synthesized data path. Experimental results show 15% power reduction in benchmark circuits.