• Journal of Applied Biological Chemistry
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• v.61 no.4
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• pp.351-355
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• 2018

Treatment towards wound healing, a complex and dynamic process, has been given a great deal of efforts in the last few decades. Focus has been imposed on developing wound dressings that meet the requirements for proper wound healing. In this study, hydrogel made from blends of poly (vinyl alcohol) and ${\beta}$-1,6-branched-${\beta}$-1,3-glucan (beta-glucan) were synthesized by modified solvent casting method for wound dressing application. Optimization of hydrogel composition and analysis of wound dressing parameters such as stability and fluid uptake capacity (in the presence of water, saline and different pH solutions) has been studied. The result indicated that the PVA/beta-glucan hydrogel hold its structural integrity even at alkaline pH (pH~9) and upholds fluids four times of its original weight. Thus, the developed hydrogel is expected to be a promising candidate as wound dressing.

• Korean Chemical Engineering Research
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• v.60 no.3
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• pp.392-397
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• 2022

Methane is one of the major greenhouse gases, recently, the biotechnological conversion from methane to high-value added chemicals have emerged as an effort to reduce methane gas emission. In this study, we optimized ectoine bio-milking conditions in which cells were repeatedly used to improve intracellular and extracellular ectoine yield from methane by using Methylomicrobium alcaliphilum 20ZDP2. First, the cultivation and intracellular ectoine accumulation conditions were optimized with respect to the growth phase and medium salinity to achieve the highest yield of synthesis. Second, ectoine excretion was optimized by determining the ectoine secretion time (15 min) in appropriate medium salinity under hypoosmotic conditions (1% NaCl). Finally, bio-milking of ectoine was successfully repeated more than 10 times using M. alcaliphilum 20ZDP2, and the ectoine yield was improved up to 129.29 mg/ DCW g.

• Microbiology and Biotechnology Letters
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• v.51 no.1
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• pp.59-68
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• 2023

Xylanase is an industrially relevant enzyme used for the production of xylobiose and xylose. Various methods are used to enhance the microbial yield of xylanase. In the present study, co-culturing of Bacillus subtilis and Bacillus pumilus were investigated using submerged fermentation for xylanase production, which was markedly increased when sal, sagwan, newspaper, wheat bran, and xylan were used as single carbon sources. Maximum xylanase production was reported after 5 days of incubation in optimized media at pH 7.0 and 37℃, resulting in 2.69 ± 0.25 µmol/min by coculture. The 1:1 ratio of sal and sagwan in optimized production media was shown to be suitable for xylanase synthesis in submerged fermentation (SMF). In comparison to mono-culture using B. pumilus and B. subtilis, co-culturing resulted in an overall 3.8-fold and 2.15-fold increase in xylanase production, respectively.

• Journal of the Korean Society of Industry Convergence
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• v.27 no.2_1
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• pp.277-285
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• 2024

Hydrogen is considered a key energy source to achieve carbon neutrality through the global goal of 'net zero'. Due to limitations in producing green hydrogen domestically, Korean companies are interested in importing green hydrogen produced overseas. The Middle East has high-quality solar energy resources and is attracting attention as a region producing green hydrogen using renewable energy. To build a green ammonia plant, optimization of the production facility configuration and economic feasibility analysis are required. It is expected that it will contribute to reviewing the economic feasibility of constructing overseas hydrogen production plants through preliminary economic feasibility analysis.

• Journal of the Korean Society of Systems Engineering
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• v.9 no.2
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• pp.83-90
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• 2013

Integrated aircraft synthesis process for rapid analysis and design is described in this paper. Data flow between different analysis fields is described in details. All the data are divided into several groups according to importance and source of the data. Analysis of design requirements and certification regulations is carried out to determine baseline configuration of an aircraft. Overall design process can be divided into initial sizing, conceptual and preliminary design phases. Basic data for conceptual design are obtained from initial sizing, CAD and geometry analysis. Basic data are required input for weight, aerodynamics and propulsion analyses. Results of this analysis are used for stability and control, performance, mission, and load analysis. Feasibility of design is verified based on analysis results of each discipline. Design optimization that involves integrated process for aircraft analysis is performed to determine optimum configuration of an aircraft on a conceptual design stage. The process presented in this paper was verified to be used for light aircraft design.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.7
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• pp.680-688
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• 2001

In this paper, we propose a reliable method for searching the optimally performing generalized brain-state-in-a-box (GBSB) neural associative memory using an evolution program (EP) given a set of prototype patterns to be stored as stable equilibrium points. First, we exploit some qualitative guidelines necessary to synthesize the GBSB model. Next, we parameterize the solution space utilizing the limited number of parameters to represent the solution space. Then, we recast the synthesis of GBSB neural associative memories as two constrained optimization problems, which are equivalent to finding a solution to the original synthesis problem. Finally, we employ an evolution program (EP), which enables us to find an optimal set of parameters related to the size of domains of attraction (DOA) for prototype patterns. The validity of this approach is illustrated by a design example and computer simulations.

• Carbon letters
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• v.14 no.4
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• pp.210-217
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• 2013

The synthesis of carbon nanomaterials (CNMs) by a chemical vapor deposition method using three different plant oils as precursors is presented. Because there are four parameters involved in the synthesis of CNM (i.e., the precursor, reaction temperature of the furnace, catalysts, and the carrier gas), each having three variables, it was decided to use the Taguchi optimization method with the 'the larger the better' concept. The best parameter regarding the yield of carbon varied for each type of precursor oil. It was a temperature of $900^{\circ}C$ + Ni as a catalyst for neem oil; $700^{\circ}C$ + Co for karanja oil and $500^{\circ}C$ + Zn as a catalyst for castor oil. The morphology of the nanocarbon produced was also impacted by different parameters. Neem oil and castor oil produced carbon nanotube (CNT) at $900^{\circ}C$; at lower temperatures, sphere-like structures developed. In contrast, karanja oil produced CNTs at all the assessed temperatures. X-ray diffraction and Raman diffraction analyses confirmed that the nanocarbon (both carbon nano beads and CNTs) produced were graphitic in nature.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.12
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• pp.1997-2003
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• 2003

Recently, there have been many researches and developments in optical disc drive by high density of track and high access speed. Therefore, the optical pick-up should guarantee highly accurate dynamic characteristics for the wide bandwidth in order to cope with this trend. These demands for optical pick-up actuator can be solved by improvements of lens-holder through the following methods. The first way is the analysis of the sensitivity matrix of design variables for vibration modes after appropriate design parameters are selected like shapes and local dimensions of a lens-holder. The second way is the optimization of design variables by calculating sequential linear programming after the problem of extending bandwidth are converted to problem of minimizing adequate objective function. In the result, modified FE model is obtained through several iterations by finite difference scheme(FDS). While results of the first way show better convergence of the target frequency, the second result shows better reduction of mass increase.

• Proceedings of the KAIS Fall Conference
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• 2011.12a
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• pp.200-203
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• 2011

A copper-based metal organic framework (MOF) named Cu-BTC, also known as HKUST-1, was synthesized by using a solvothermal method at various synthesis temperature, time and pressure. The obtained samples were characterized with Powder X-ray diffraction (XRD) for phase structure, scanning electron microscopy (SEM) for crystal structure, and nitrogen adsorption-desorption for pore textural structure. The Cu-BTC sample was also studied for $CO_2$ adsorption. The analysis results displayed that the sample synthesized at the condition of temperature: $120^{\circ}C$, synthesis time: 12 hours, pressure: 1 bar exhibited a good crystal structure with uniform size of octahedral particles. The BET data revealed a high surface area of 1741.7 $m^2g^{-1}$ and a pore volume of 0.7137 $cm^3g^{-1}$and exhibiteda maximum $CO_2$ adsorption capacity of 170 mg/g of the sorbent at $25^{\circ}C$.

• Journal of Information Processing Systems
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• v.13 no.5
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• pp.1183-1202
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• 2017

Image restoration has been carried out by texture synthesis mostly for large regions and inpainting algorithms for small cracks in images. In this paper, we propose a new approach that allows for the simultaneous fill-in of different structures and textures by processing in a wavelet domain. A combination of structure inpainting and patch-based texture synthesis is carried out, which is known as patch-based inpainting, for filling and updating the target region. The wavelet transform is used for its very good multiresolution capabilities. The proposed algorithm uses the wavelet domain subbands to resolve the structure and texture components in smooth approximation and high frequency structural details. The subbands are processed separately by the prioritized patch-based inpainting with isophote energy driven texture synthesis at the core. The algorithm automatically estimates the wavelet coefficients of the target regions of various subbands using optimized patches from the surrounding DWT coefficients. The suggested performance improvement drastically improves execution speed over the existing algorithm. The proposed patch optimization strategy improves the quality of the fill. The fill-in is done with higher priority to structures and isophotes arriving at target boundaries. The effectiveness of the algorithm is demonstrated with natural and textured images with varying textural complexions.