• 대한한의학회지
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• 제44권3호
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• pp.150-162
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• 2023

Meniere's disease is characterized by episodic vertigo, fluctuating hearing loss, tinnitus and ear fullness. The main pathological finding is endolymphatic hydrops, but the etiology of disease and effective treatment methods are still disputed. Recently, Cervical spine disorders(CSD) and Temporomandibular disorders(TMD) have been attracting attention as one of the causes of Meniere's disease. A 65-year-old female Meniere patient with musculoskeletal problems in the cervical and mandible area was treated by Korean medical therapies including pharmacoacupuncture treatment. After 5 weeks of treatment, there was no meaningful change in hearing level evaluated with pure tone audiometry, but the subjective symptoms of Meniere improved significantly. Numerical rating scale (NRS) decreased from 10 to 0 for hearing loss, 10 to 3 for tinnitus and 8 to 3 for ear fullness. Also NRS of cervicalgia was reduced from 5 to 0 after treatment. The result suggests that the Korean medical therapy including pharmacoapuncture targeting CSD and TMD could be safe and effective method for patients with Meniere's disease.

• 대한한의학회지
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• 제30권5호
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• pp.77-87
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• 2009

Objectives: This study aimed to evaluate the effect of purgation therapy with Natrii sulfas, an oriental medical therapy for stroke patients with constipation, on physiological indexes and the brain edema of rats. Methods: Brain edema was induced by the middle cerebral artery occlusion (MCAO); Natrii sulfas was administered once after the MCAO. At 3, 6, 15, 24, 48 hours after reperfusion, physiological indexes such as fecal weight, urine volume and water content in stool were assessed, and at 48 hours after reperfusion the edema index was measured. Results: 1. Purgation therapy with Natrii sulfas significantly improved the reduction of fecal weight caused by ischemic insult (P<0.05). 2. Purgation therapy with Natrii sulfas significantly improved the reduction of urine volume caused by ischemic insult (P<0.05). 3. Purgation therapy with Natrii sulfas significantly improved the reduction of water content in stool caused by ischemic insult (P<0.05). 4. Purgation therapy with Natrii sulfas did not improve the neurological symptom caused by ischemic insult. 5. Purgation therapy with Natrii sulfas did not attenuate the total infarct volume caused by ischemic insult. 6. Purgation therapy with Natrii sulfas attenuated the brain edema caused by ischemic insult (P<0.05). Conclusions: These results suggest that purgation therapy with Natrii sulfas improves some important symptoms and has a protective effect on the brain edema caused by ischemic insult.

• 대한한방내과학회지
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• 제40권2호
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• pp.220-227
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• 2019

Objectives: Parkinson's disease is the neurodegenerative disease that affects both motor and non-motor function, including postural instability. Camptocormia is an abnormal condition in which the thoracolumbar spine bends forward during walking or standing. However, the treatment options are limited and often not effective. The purpose of this study was to report on the Korean medical treatment of a Parkinson's disease patient with postural instability who presented with camptocormia. Methods: We used Korean medical treatment including herbal medicine (Jemageopung-tang), acupuncture and pharmacopuncture therapy to the patient who was admitted to the hospital for 21 days. The clinical symptoms were assessed with the Unified Parkinson's Disease Rating Scale (UPDRS) and walking time without assistance. Results: After treatment, the UPDRS Parts 2 and 3 scores were decreased from 5 to 3 and 20 to 9, respectively. Also, the walking time without assistance was improved. Conclusion: This study suggested that Korean medical treatment could be an effective option for treating Parkinson's disease with postural instability.

• 대한장애인치과학회지
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• 제13권2호
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• pp.108-113
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• 2017

MMD 환자는 심한 울음이나 운동 등으로 유발되는 과호흡성 뇌혈류량 감소에 주의해야 하며, 특히 소아 환자의 경우 낯선 환경에서 쉽게 울음을 터뜨리는 경향이 있고, 뇌의 산소요구량이 많으며, 뇌혈류량 변화에 민감하므로 치과 진료 시에 더욱 세심한 관리가 필요하다. 본 증례는 발달 지연을 동반하여 일상의 구강 위생 관리 및 치과 검진에 비협조적이고, 다수 치아에 광범위한 우식증을 보이는 발달장애가 있는 MMD 소아 환자를 전신 마취 하에 안전하고 효과적으로 치료한 사항을 보고하는 바이다. 환아는 이전에 수차례의 뇌경색 증상을 보여 뇌혈관 문합술을 받은 바 있고, 발달 지연 외에도 지적 장애, 언어장애, 편마비, 연하장애, 사시증을 동반하였다. 환아의 기저 질환과 협조도, 우식의 심도를 고려하여 세보플루레인을 이용한 전신 마취를 행동조절 요법으로 선택하였고, 술 전 정맥로 확보 시 환아의 불안을 조절하기 위해 미다졸람 경구 투여를 시행하였다. 모든 생징후를 안전하게 감시하며 성공적으로 치과 치료를 마친 후, 적극적인 통증 조절을 위해 아세트아미노펜 경구 투여를 시행하였다. 전신마취 이후에는 정기 검진 및 불소 도포를 통해 환자의 구강 건강 증진에 기여할 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제24권6호
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• pp.515-522
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• 2003

인두는 구강과 식도, 비강과 폐의 중간에서 능동적으로 구강을 통해 섭취되는 음식물과 비강을 통해 흡입되는 공기의 통로역할을 하는 주요한 기관이다. 본 연구는 유한요소기법을 이용한 인두의 3차원 구조의 재구성 과정을 거쳐 인두의 생체역학모델을 구현하였으며, 연하곤란환자의 인두근육의 주요부분에 대한 구조적 변형특성을 3가지로 분류하여 유한요소기법을 이용하여 인두내의 압력에 대한 형상의 변형을 관찰 후 최적화 과정을 거쳐 각 부분에서의 추정 압력 구배를 측정하여 연하과정에서 내부에 생성되는 압력의 연속적인 압력분포를 추정하였다. CT에 의한 인두의 변형 형상을 추정하여 임의 압력에 의한 인두구조의 변형 형상을 유한요소 해석에 의해 계산한 후 비교하여 실제 인두강 내에 형성되는 압력을 추정하였다. 재료적 특성은 인두의 기능이상 시 근조직경화가 발생, 즉 stiffness 가 증가하는 것으로 가정하여 응력-변형률 관계에 있어서 각각 $25\%,\;50\%,\;75\%$씩 증가시켜 분석하였다. 이러한 인두의 생체역학모델은 인두기능장애를 가진 환자의 치료 계획 수립에 도움이 되는 유용한 자료를 제공 할 것으로 생각된다.

• 보건행정학회지
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• 제30권2호
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• pp.231-244
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• 2020

Background: As the population is aging, chronic diseases and depression are becoming the main problems in a country's healthcare system. In this study, we aimed to explore the associations between chronic diseases and depression among the elderly in South Korea. Methods: We analyzed 9,975 (men, 4,147; women, 5,828) respondents obtained from the 2014 National Survey of Living Conditions and Welfare Needs of Korean Older Persons. Our dependent variable was either 1 or 0 according to whether a respondent had depression or not, where depression was defined when the Short Form of Geriatric Depression Scale score was 8 or more points. Variables of interest were 24 types of chronic diseases and covariates included various socio-demographic and health behavior characteristics. We performed Rao-Scott chi-square tests and hierarchal logistic regression analyses by gender, reflecting the characteristics of the survey. Results: A significant difference was found in the proportion of having depression between genders (men 18.9% vs. women 23.4%). According to fully adjusted, multivariable analyses, for elderly men, relative to those without any chronic disease, the odds ratio of depression was 1.56 (95% confidence interval [CI], 1.10-2.22) in the stroke patients group and 1.82 (95% CI, 1.01-3.25) in the osteoporosis patients group. For elderly women, the odds ratio was 1.96 (95% CI, 1.28-3.00) in the fracture/dislocation and aftereffects patients group and 1.30 (95% CI, 1.03-1.64) in the group of patients with other diseases. Conclusion: Even after being adjusted for diverse characteristics, some chronic diseases were significantly associated with depression in the elderly and the association differed between genders. Therefore, public health and medical interventions are needed to manage such chronic diseases together with curing depression symptoms.

• 대한한의학방제학회지
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• 제18권2호
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• pp.25-51
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• 2010

This report describes 214 prescriptions including Angelicae Gigantis Radix and Cnidii Rhizoma in Dongeuibogam. Angelicae Gigantis Radix and Cnidii Rhizoma have been used separately or concurrently in Oriental Medicine for a long time as a treatment for various diseases. The following conclusions are reached through investigations on the applications of prescriptions including Angelicae Gigantis Radix and Cnidii Rhizoma in Dongeuibogam. 1. 34 times(15.9%) prescriptions are recorded in women chapter, 24 times(11.2%) in wind chapter, 13 times(6.1%) in children chapter and 12 times(5.6%) in intumescence chapter, which are arranged in order of frequency. 2. Treating blood, stroke and fetal movement are ranked top, regulating blood, headache, cataract, carbunculosis, pregnancy, abortion, underdevelopment, etc, among 137 symptoms in prescriptions including Angelicae Gigantis Radix and Cnidii Rhizoma. 3. The dosages of Angelicae Gigantis Radix and Cnidii Rhizoma are ranged from 2.5 pun~6 nyang. 1 jeon is recorded 54 times(25.2%), 7 pun is 29 times(13.6%), 5 pun is 24 times(11.2%), 1 nyang is 21 times(9.8%), same amount is 11 times(5.1%), 5 pun is 10 times(4.7%), 8 pun is 9 times(4.2%) used among 187 prescriptions including Angelicae Gigantis Radix and Cnidii Rhizoma. 4. The dosages of Angelicae Gigantis Radix and Cnidii Rhizoma are ranged from 2.5 pun~6 nyang. 2.5 pun~1.5 jeon, 2 jeon~6 nyang, same amount which are recorded by percent(decoction groups: the other groups) are 69.0%(98.0:2.0%), 25.5%(18.5:81.5%), 5.1%(18.2:81.8%) respectively. The less using dosage of Angelicae Gigantis Radix and Cnidii Rhizoma has a more percentage of decoctions groups, The more using dosage of Angelicae Gigantis Radix and Cnidii Rhizoma has a more percentage of the other groups except decoctions. The less using prescriptions have an effects of controling menstrual pain, enhancing blood and chi, etc, as a whole. The more using prescriptions as a form of compound powder have an effects in epilepsy, chronic diseases, etc. 5. The 214 prescriptions including Angelicae Gigantis Radix and Cnidii Rhizoma in Dongeuibogam are mainly composed of Goongguitang, Samooltang, Sagoonjatang and Gobangpoongtang, etc.

• 대한한의학회지
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• 제17권1호
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• pp.302-328
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• 1996

I. 연구개발(硏究開發)의 목적(目的) 및 중요성(重要性) 한국(韓國) 임상자료(臨床資料)를 효과적(效果的)으로 모으기 위한 자료수집용(資料收集用) 진료부(診療簿) 형식(形式)을 고안(考案)함으로써 전문가(專門家)의 지식(知識)을 체계적(體系的)으로 수집(收集)하고 통계분석시(統計分析時) 유효(有效)한 결과(結果)를 기대(期待)할 수 있도록 한다. 진료부(診療簿) 형식(形式)은 개인별(個人別) 편차(偏差)가 심(甚)한 한국(韓國) 임상자료(臨床資料)의 문제점(問題點)을 수집단계(收集段階)에서 해결(解決)하는데 매우 중요(重要)하며 또한 수집(收集)된 자료(資料)는 전문가(專門家)시스템의 지식(知識)으로 제공(提供)되므로 핵심적(核心的)인 연구자료(硏究資料)가 된다. II. 연구개발(硏究開發)의 내용(內容) 및 범위(範圍) 임상자료(臨床資料) 수집(收集)을 위한 진료부형식(診療簿形式)의 고안(考案), 임상자료(臨床資料) 분석(分析), ODS의 진단(診斷)과 전문가(專門家) 진단(診斷)의 비교(比較)를 내용(內容)으로 하며, 연구범위(硏究範圍)는 한의(韓醫) 임상자료중(臨床資料中) 많은 환자분포(患者分布)를 보이고 있는 중풍환자(中風患者)를 대상(對象)으로 이와 관련(關聯)된 지식(知識) 및 용어(用語)를 정리(整理)하되 중풍환자(中風患者)는 CT로 뇌혈관질환(腦血管疾患)이 확인(確認)된 환자(患者)로 한정(限定)하였다. III. 연구개발결과(硏究開發結果) 및 활용(活用)에 대한 건의(建議) 자료수집용(資料收集用) 진료부(診療簿)는 임상자료(臨床資料)의 수집(收集), 관련지식(關聯知識) 및 용어정리(用語整理), 그리고 타(他) 진료기관(診療機關)의 임상자료수집(臨床資料收集)에 활용(活用)하며, 임상자료(臨床資料)에 대한 평가분석(評價分析)의 결과(結果)는 차후 타(他) 질환자료(疾患資料) 수집(收集)이나 시스템구축(構築)에 필요(必要)한 임상자료(臨床資料)로 활용(活用)된다. 또한 이 자료(資料)는 임상교육(臨床敎育) 및 임상자료(臨床資料)를 통(通)한 한양방(韓洋方)의 협진자료(協診資料)로 활용(活用)될 수 있을 것으로 기대(期待)된다.

• 대한임상검사과학회지
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• 제39권2호
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• pp.141-146
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• 2007

Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a disorder characterized by the repetitive collapse of the pharyngeal airway during sleep, which leads to oxygen desaturation, sleep fragmentation, daytime sleepiness, and increased risk for hypertension and stroke. We investigated the clinical factors related to the severity of OSAHS. Polysomnography was performed in three hundred and ninety five consecutive adult patients with clinical symptoms of obstructive sleep apnea syndrome. All patients completed the sleep questionnaire and the Epworth Sleepiness Scale before polysomnography. Patients were classified into four groups based on the severity of their polysomnographic data: Non-OSA group, characterized by Apnea-Hypopnea Index (AHI) < 5; mild OSA group, by AHI 5-15; moderate OSA group, by AHI 16-30; and severe OSA group, by AHI > 30. Neck circumference was also measured at the cricothyroid level. A total of 395 patients (336 men and 59 women) were studied. In the non-OSA group, there were 55 patients; their mean neck circumference was $39.63{\pm}4.24cm$ and mean BMI was $24.48{\pm}3.53$. In the mild group, there were 101 patients; their mean neck circumference was $41.93{\pm}3.75cm$ and mean BMI was $25.33{\pm}2.94$. In the moderated group, there were 93 patients; their mean neck circumference was $43.27{\pm}3.50cm$ and BMI was $25.90{\pm}2.88$. In the severe group, there were 146 patients; their mean neck circumference was $44.94{\pm}3.93cm$ and mean BMI was $26.81{\pm}3.76$. Men had significantly larger neck circumference than women ($Mean{\pm}SD$, $43.72{\pm}3.83$ vs $39.17{\pm}4.30$, p < 0.001), and higher AHI than women ($29.12{\pm}22.65$ vs $14.63{\pm}14.11$, p < 0.001). Multiple regression analysis revealed that neck circumference was the most significant predictor of AHI. Neck circumference and BMI were positively correlated with the severity of OSAHS. The severity of OSAHS was greater in men than in women.

• 디지털융복합연구
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• 제12권3호
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• pp.353-358
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• 2014

급성기 허혈성 뇌졸중 증상이 있는 뇌 관류 CT 검사를 시행한 환자를 대상으로 장비사가 제시한 고정 시간 기법(Fixed time technique)과 조영제 추적 기법(Bolus tracking technique)을 비교하여 환자의 피폭선량을 분석하고자 하였으며, 조영제 추적 기법의 유용성과 최적의 조영증강 구간을 구현하는 Time graph를 알아보기 위한 것이다. 환자에서는 PCT의 $CTDI_{VOL}$은 고정시간기법에서 431.72mGy, Bolus tracking에서 323.61mGy로 측정되었고, DLP값은 고정시간기법에서 $1243.47mGy{\cdot}cm$, Bolus tracking에서 $932mGy{\cdot}cm$로 측정되었다. Time graph는 고정시간기법에서 다양하게 나타났으나, Bolus tracking 기법에서는 최적의 Time graph를 얻을 수 있었으며, 뇌 관류 CT검사 시 Bolus tracking기법을 적용하여 피폭선량을 25% 정도 감소시킬 수 있었다.