• Title/Summary/Keyword: Symptom Improvement

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The Association of Trust, Social Participation with Self-Rated Health Status - Mediating Effect of Depression - (신뢰, 사회활동 참여와 지각된 건강수준과의 관련성 - 우울감의 매개효과 -)

  • Lee, Jin Hyang;Park, Ki-Soo;Jeon, Hye Ji;Yang, Hyun Su;Kim, Bokyoung;Choe, Sung Pil Michael
    • Journal of agricultural medicine and community health
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    • v.38 no.4
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    • pp.257-266
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    • 2013
  • Objectives: This study was performed to investigate the relationship between individual-level social capital and depression. And, we assessed if depressive symptom mediates the relationship between social capital and self-rated health status. Methods: Data from the 2011 Community Health Survey were analyzed for this study. We used chi-square tests and analyzed a four step approach in which several regression analyses were conducted and significance of the coefficients was examined at each step. Results: In men, the results of controlling mediating factor (depression): social participation was not significantly associated with self-rated health status(p=0.082), the finding supports that social participation was fully mediated by depression. In women, the relationship between social capital(trust, social participation) and self-rated health status was partially mediated by depression. Conclusions: In order to increase self rated health status, not only improvement in trust and social participation are needed but effort to reduce depression must be combined.

Pilot Study on Characterization of Patients with Low Back Pain: Multi-center, Prospective, Observation Study (요통 환자의 특성 조사 예비 연구: 다기관, 전향적, 관찰연구)

  • Park, Chang-Hyun;Jang, Bo-Hyoung;Ko, You-Me;Park, Dong-Su;Kim, Soon-Joong;Park, Won-Hyung;Cha, Yun-Yeop;Ko, Seong-Gyu;Song, Yun-Kyung
    • Journal of Korean Medicine Rehabilitation
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    • v.26 no.2
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    • pp.123-132
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    • 2016
  • Objectives The aim of this study done as pilot study is to analyze the current state of patients who have low back pain through registry. Methods This study is done under approval of Gil Oriental Medical Hospital of Gachon University, Oriental Medical Hospital of Sangji University, Jecheon Oriental Medical Hospital of Se-Myung University IRB. Among subjects who signed the consent form by their own will, we decided whom to register as subjects of this study by the standard of selection and exception. We collected the sociological investigation, character of low pack pain, degree of symptom which they felt before and after the hospitalization from registered subjects. Results 1. The number of the subjects is 16. The average age is 41.0. 9 of them are female, 7 of them are male. Most of the subjects have history illness which has connection with low pack pain. 2. According to the patient's free description of the back pain, 6 of them suffered throbbing pain. And 8 of the patients have chronic pain, 6 of them have intermittent pain of back pain analysing the character of the low back pain. They answered the pain lasted for 47.6 minutes on average. 3. About the change on the average R.O.M. of L-spine, R.O.M. of Lateral bending, Extension, Flexion, Rotation has increased after leaving the hospital compared with before hospitalization. 4. The amount of discomfort or strength of pain, which was checked by VAS on the day of leaving the hospital, has decreased than they were before the hospitalization. And there was the improvement on the dysfunction score and EQ-5D. Conclusions Through this study, we specifically analyzed the symptoms of the low back pain by accumulating the analysis about the symptoms using several indicators and description which is freely spoken by patients about their symptoms. Further research is expected to complete multi-center registry by building registry and by using it, to get various epidemiologic informations about low back pain.

Institutional Ethnography on Organization of Case Management Practice at a Mental Health Center (정신보건센터 사례관리 실천의 조직화에 관한 제도적 문화기술지)

  • Ha, Ji Seoun
    • Korean Journal of Social Welfare
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    • v.68 no.4
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    • pp.199-224
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    • 2016
  • This study is a research that investigated organization of case management practice at a mental health center. For organization research of case management practice, this study applied the research method of Institutional Ethnography, and analyzed 'work knowledge' and 'texts' data which were obtained through field work that lasted 3 months with 11 study participants. The analysis is not interpretation of the researcher, but it is work that assembles 'work knowledge' of field workers until they reach discovering institutions that organize case management practice. As a result of this study, case management practice of the mental health center was being standardized as 'a service that is biased towards symptom management without comprehensive and continual resources links' by new public management theory, bio-medicine discussion, 'standardization policy', 'treatment rate improvement policy', 'performance-based budget system', 'performance evaluation system' and 'continual linkage policy', mediating texts. This is a different outcome from usefulness of case management that is claimed to support politically.

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Safety and Effectiveness of Long Acting Injectable Antipsychotic Paliperidone Palmitate Treatment in Schizophrenics : A 24-Week Open-Label Study (조현병 환자에서 장기지속형 항정신병 주사제 팔리페리돈 팔미테이트의 효능과 안전 : 24주 개방형 연구)

  • Kang, Hyun-Ku;Hahm, Woong;Shon, In-Ki;Paik, In-Ho
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.111-117
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    • 2013
  • Objectives We investigated the effectiveness and safety when treated in schizophrenics with paliperidone palmitate, a long acting injectable antipsychotic. Methods This was a 24-week open-label study, performed at one center in Korea. The eligible patients with schizophrenia diagnosed by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria were enrolled. Patients received long-acting paliperidone palmitate injection (234 mg, baseline; 156 mg, week 1 ; then once 4 weeks flexible dosing). Effectiveness assessments were measured by the Positive and Negative Syndrome Scale (PANSS), The Clinical Global Impression Severity Scale (CGI-S), The Personal and Social Performance (PSP) at baseline, week 1, every 4 weeks untill 24 weeks or endpoint. Safety assessments were measured by The Extrapyramidal Symptom Rating Scale (ESRS), body weight (BW) and incidence of adverse events. Oral antipsychotics were stopped or tapered off within next 14 days. Results Of 20 patients recruited, 9 patients (45%) completed the study. Paliperidone palmitate produced a significant improvement in PANSS total score from baseline to endpoint. The response rate was 75% [mean change (${\pm}SD$) $-25.9{\pm}14.4$, all p < 0.001]. The CGI-S and PSP total scores significantly improved during 24 weeks (All p < 0.001). Eighty percent of patients reported adverse events and most common adverse events (${\geq}10%$) in paliperidone palmitate were anticholinergic adverse event, extrapyramidal symptoms, weight gain, akathisia, insomnia, headache, agitation, anxiety and GI trouble. ESRS score is not statistically significant, but tends to get better at the end of the study when compared to baseline. Conclusions Our study results demonstrated maintained effectiveness and safety of paliperidone palmitate treatment in schizophrenics. And provides both clinicians and patients with a new choice of treatment that can improve the outcome of long term therapy. Their potential effectiveness and safety should be better addressed by future randomized-controlled trials.

Retrospective Study of Patients with Cough Treated with Eunhwayeongyo-tang (은화연교탕(銀花連翹湯)을 투여한 기침 환자에 대한 후향적 연구)

  • Baek, Hyun-jung;Lee, Beom-joon;Jung, Sung-ki;Jung, Hee-jae
    • The Journal of Internal Korean Medicine
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    • v.37 no.6
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    • pp.961-977
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    • 2016
  • Objectives: This study was designed to analyze the treatment effects of Eunhwayeongyo-tang through retrospective chart reviews. We also checked the correlation between each pair of variables of the symptoms and curative rates of patients with cough. Methods: Thirty-three patients with cough who had satisfied the selection criteria were retrospectively reviewed through their basic medical records, nasal endoscopy, and questionnaires about cough on their first and second visits. The questionnaires used were "The questionnaire on clinical symptoms of cough & sputum", Leicester Cough Questionnaire Korean Version (LCQ-K), Total Nasal Symptom Scores (TNSS), Visual Analog Scale (VAS), and "Cold-heat patterns". The improvement rate, calculated by "The questionnaire on clinical symptoms of cough & sputum" was considered to be clinically effective if reduction of symptoms scored more than 30%. The state of nasopharyngeal mucosa was assessed to categorize the cold-heat patterns of the upper respiratory tract and for diagnosis. Results: According to this study, cough and sputum improved by $57.22{\pm}37.76%$. Most patients (76%) improved significantly after $12.18{\pm}6.59days$ of taking Eunhwayeongyo-tang. The cure rates of 26 patients among the 33 patients were judged as effective. All the mean scores of the questionnaires and the anterior nasal cavity states were significantly improved on the patients' second visits. After $18.39{\pm}15.68days$, 30 patients were completely cured and ended treatment. The nasopharyngeal mucosa states of all patients were categorized as heat patterns. Conclusions: The conditions of the patients with nasopharyngitis significantly improved after taking Eunhwayeongyo-tang. All of the patients had pharyngitis or rhinitis. The cold-heat pattern of nasopharyngeal mucosa was a significant indicator of upper respiratory inflammation diagnosis.

Effects of Phellinus linteus-Barley corn Water Extract in Triton WR-1339(TX)-Induced Hiperlipidemic Rats (상황버섯보리의 기능성에 관한 연구)

  • Suk, Min-Hee;Kang, Kyung-Hwa;Choi, Young-Hyun;Choi, Byung-Tae;Park, Sung-Ha
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.6
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    • pp.1424-1431
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    • 2007
  • This study was designed to observe the effects of the Phellinus linteus-Barley corn water extract (PLBC) on the improvement of the blood biochemical aspects; serum AST, ALT, LDH, ALP, Phospholipid, Trigryceride, Total Cholesterol, HDL, LDL, of Triton WR-1339(TX)-induced hiperlipidemic rats. Experimental groups were designed to normal control group(Normal), hiperlipidemic control group(Control), hiperlipidemic control group treated with Barley corn water extract(1000mg/1kg ; BC), hiperlipidemic control group treated with Phellinus linteus-Barley corn water extract (500, 1000, 1500mg/1kg; PLBC-1, PLBC-2, and PLBC-3, respectively). Serum AST levels of BC and all PLBC treated groups were significantly decreased (p<0.005) compared to Control group. Serum ALT levels of BC and PLBC-2 groups were decreased (p<0.05), PLBC-1 and PLBC-3 groups were significantly decreased (p<0.005) compared to Control group. Serum LDH levels of BC group was decreased but no significant, PLBC-1 and PLBC-2 groups were decreased (p<0.05), PLBC-3 group was significantly decreased (p<0.025) compared to Control group. Serum ALP levels of BC and PLBC-1 groups were decreased (p<0.05), PLBC-2 group was decreased but no significant, PLBC-3 group was significantly decreased (p<0.005) compared to Control group. Serum Phospholipid levels of BC group was decreased but no significant, PLBC-1 group was decreased (p<0.025), PLBC-2 and PLBC-3 groups were significantly decreased (p<0.005) compared to Control group. Serum Triglyceride levels of BC group was increased but no significant, PLBC-1 group was decreased but no significant, PLBC-2 and PLBC-3 groups were significantly decreased (p<0.005) compared to Control group. Serum Total cholesterol levels of BC group was decreased (p<0.05), PLBC-1, PLBC-2 and PLBC-3 groups were significantly decreased (p<0.005) compared to Control group. Serum HDL levels of BC group was increased (p<0.05), PLBC-1 and PLBC-2 groups were significantly increased (p<0.005), PLBC-3 group was increased (p<0.025) compared to Control group. Serum LDL levels of BC, PLBC-1 and PLBC-2 groups were decreased but no significant, PLBC-3 group was significantly decreased (p<0.005) compared to Control group. These results suggested that Phellinus linteus-Barley corn water extract improve Triton WR-1339(TX)-induced hiperlipidemic symptom in rats.

A Case of Continuous Positive Airway Pressure Therapy in a Patient with Central Sleep Apnea and Heart Failure (중추성 수면 무호흡이 동반된 심부전 환자에서 지속적 상기도 양압술 적용 1례)

  • An, Jee Young;Kim, Shin Bum;Kang, Hyeon Hui
    • Sleep Medicine and Psychophysiology
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    • v.24 no.2
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    • pp.118-123
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    • 2017
  • Central sleep apnea (CSA) is a highly prevalent comorbidity in patients with heart failure and may present in 25 to 40 percent of heart failure patients. Continuous positive airway pressure (CPAP) is the primary therapeutic option and effective in treatment of obstructive sleep apnea (OSA). In heart failure patients with CSA, several trials of CPAP showed a number of positive effects in heart failure treatment. A 58-year-old male visited the hospital because of dyspnea and he was diagnosed as heart failure with ischemic heart disease. He underwent coronary angiography and received percutaneous coronary intervention due to stenosis at the middle of left anterior descending coronary artery. However, dyspnea was not completely improved after treatment with percutaneous coronary intervention. The patient also experienced snoring and sleep apnea which worsened with symptom of dyspnea in the recent year. We suspected CSA and the patient underwent polysomnography to confirm whether sleep apnea was present. During the polysomnography, CSA with Cheyne-Stokes respiration (CSR) was observed and apnea-hypopnea index was 45.9/hr. The patient was treated with CPAP. After CPAP treatment, hypoxemia and CSA were resolved and dyspnea was improved with reducing NYHA class. We report a case successfully treated with clinical improvement by presuming CSA in a patient with heart failure.

Quality of Life for Patients with Esophageal/Gastric Cardia Precursor Lesions or Cancer: A One-year Prospective Study

  • Wen, Ying;Pan, Xiong-Fei;Huang, Wen-Zhi;Zhao, Zhi-Mei;Wei, Wen-Qiang;Chen, Feng;Lan, Hui;Huang, He;Yang, Chun-Xia;Qiao, You-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.45-51
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    • 2015
  • Background: The current study examined health-related quality of life (QoL) for patients with esophageal/gastric cardia precursor lesions or cancer before and after treatment to facilitate improved prevention and treatment. Materials and Methods: Patients with different stages of esophageal/gastric cardia lesions completed two QoL questionnaires, EORTC QLQ-C30 and supplemental QLQ-OES 18, before primary treatment, and at 1, 6 and 12 months after treatment. Results: Fifty-nine patients with precursor lesions, 57 with early stage cancer, and 43 with advanced cancer responded to our survey. Patients with precursor lesions or early stage cancer reported better QoL overall than those with advanced cancer before treatment (p<0.01). Global QoL scores before treatment and at 1 month after treatment were $71{\pm}9$ versus $69{\pm}9$ (p>0.01), $71{\pm}8$ versus $61{\pm}11$ (p<0.01), $67{\pm}11$ versus $62{\pm}9$ (p<0.01) for three stages of lesions. At 6 months after treatment, some QoL measures recovered gradually in precursor lesion and early cancer patients, while some continuously deteriorated in advanced cancer patients. At 12 months, all QoL scores were comparable to baseline for patients with precursor lesions (p>0.01), while global QoL, social, pain, and insomnia scores for early stage and advanced cancer were inferior to corresponding baseline levels (difference between means>5, p<0.01). At this time point, compared with patients with early stage cancer, those with advanced cancer showed worse QoL with all function and most symptom measures (p<0.01). Conclusions: Patients with precursor lesions or early stage esophageal/gastric cardia cancer show better QoL than those with advanced cancer. This indicates that screening, early diagnosis and treatment may improve the QoL for esophageal/gastric cardia cancer patients. Target intervention and counseling should be given by health care providers during treatment and follow-up to facilitate QoL improvement.

Statistical Analysis of Subjective Symptoms of Respiratory Disease and Factors Related to Prevalent Status among Dental Technicians (치과기공사의 호흡기 질환 자각증상과 유병상태 관련 요인)

  • Oh, Seon-Mi;Kwon, Eun-Ja
    • The Journal of the Korea Contents Association
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    • v.11 no.10
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    • pp.355-369
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    • 2011
  • The purpose of this study was to determine the subjective symptoms of respiratory disease and factors related to prevalent status among dental technicians by analyzing the questionnaire data from 300 dental technicians in Seoul and GyeongGi-Do, using SPSS WIN 18.0 program. The results are followings; 1. There were significant differences among subjects in the normal complaints rate for cough by presence smoking, total career, and work days per week. 2. There was significant difference among subjects in the normal complaints rate for sputum only by work days per week.(P<0.05) 3. There were significant differences among subjects in the normal complaints rate for continuance of sputum or congestion by work days per week and required measures for improvement in pain. 4. There were significant differences among subjects in the normal complaints rates for blocked nose and coryza by sex, age, work days per week and average length of breaking time during working (P<0.05). 5. There were significant differences among subjects in the normal complaints rates for shortness of breath by sex, exercise frequency, average length of exercise, main job. 6. There was significant difference among subjects in the experience rate due to symptom of pulmonary disease only by main job.(P<0.05).

Outcome of Extraarticular Dorsal Closing Wedge Osteotomy for Freiberg's Disease (관절외 배부 폐쇄 쐐기 절골술을 이용한 Freiberg병의 치료 결과)

  • Lee, Jun Young;Kim, Woong Hee;Jung, Sung;Yang, Sung Hun
    • Journal of Korean Foot and Ankle Society
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    • v.20 no.3
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    • pp.126-130
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    • 2016
  • Purpose: The aim of this study was to evaluate the result of extraarticular dorsal closing wedge osteotomy in Freiberg's disease. Materials and Methods: Between February 2012 and July 2014, total 10 patients who underwent dorsal closing wedge osteotomy and followed up more than 1 year were selected for inclusion. Average age was 16.3 years, and average follow-up period was 15.5 months. The diagnosis was made using magnetic resonance imaging of those with a limitation in walking or usual activity due to pain in the metatarsal head. During operation, we removed loose body, and synovectomy was done. Osteotomy at the metatarsal neck and fixation with Kirschner wire were performed. X-ray was taken to check shortening of 2nd metatarsal and bone union. Moreover, we checked the active range of motion of 2nd metatarsophalangeal joint before and after surgery. At the last follow-up, the shortening of metatarsal, American Orthopaedic Foot and Ankle Society (AOFAS) score, visual analogue scale (VAS), and patient's subjective satisfaction were evaluated. Results: According to the Smillie's stage, there were 3 cases of stage II, 4 cases of stage III, and 3 cases of stage IV. Average bone union time on the osteotomy site was 8 weeks. Average shortening of metatarsal was 2.53 mm. Average AOFAS score improved significantly from 56.9 to 82.8 points at final follow-up (p<0.05), and average VAS score also improved significantly from 6.4 to 1.4 points at final follow-up (p<0.05). Average active range of motion at metatarsophalangeal joint improved from $28.0^{\circ}$ preoperatively to $46.5^{\circ}$ at the final follow-up. Other complications, such as metatarsalgia and arthritis, were not found; however, there was 1 case of delayed union with no symptom. Conclusion: In Freiberg's disease, dorsal closing wedge osteotomy is recommended for the improvement of clinical symptoms and range of motion.