• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.11
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• pp.66-76
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• 2009

The motion estimation in video encoding system occupies the biggest part. So, we require the motion estimator with efficient structure for real-time operation. And for motion estimator's implementation, it is desired to design hardware module of an exclusive use that perform the encoding process at high speed. This paper proposes motion estimation detection block(MED), 41 SADs(Sum of Absolute Difference) calculation block, minimum SAD calculation and motion vector generation block based on parallel processing. The parallel processing can reduce effectively the amount of the operation. The minimum SAD calculation and MED block uses the pre-computation technique for reducing switching activity of the input signal. It results in high-speed operation. The MED and 41 SADs calculation blocks are composed of adder tree which causes the problem of critical path. So, the structure of adder tree has changed the most commonly used ripple carry adder(RCA) with carry skip adder(CSA). It enables adder tree to operate at high speed. In addition, as we enabled to easily control key variables such as control signal of search range from the outside, the efficiency of hardware structure increased. Simulation and FPGA verification results show that the delay of MED block generating the critical path at the motion estimator is reduced about 19.89% than the conventional strukcture.

• International Journal of Oral Biology
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• v.31 no.4
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• pp.113-118
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• 2006

In the primary sensory neuron of the mesencephalic trigeminal nucleus (MTN), the peripheral axon supplies a large number of annulospiral endings surrounding intrafusal fibers encapsulated in single muscle spindles while the central axon sends only a few number of synapses onto single ${\alpha}-motoneurons({\alpha}-MNs)$. Therefore, the ${\alpha}-{\gamma}$ linkage is thought to be very crucial in the jaw-closing movement. Spike activity in a ${\gamma}-motoneuron\;({\gamma}-MN)$ would induce a large number of impulses in single peripheral axons by activating many intrafusal fibers simultaneously, subsequently causing an activation of ${\alpha}-MNs$ in spite of the small number of synapses. Thus, the activity of ${\gamma}-MNs$ may be vital for modulation of jaw-closing movements. Independently of such a spindle activity modulated by ${\gamma}-MNs$, somatic depolarization in MTN neurons is known to trigger the oscillatory spike activity. Nevertheless, the trafficking of these spikes arising from the two distinct sources of MTN neurons is not well understood. In this short review, switching among multiple functional modes of MTN neurons is discussed. Subsequently, it will be discussed which mode can support the ${\alpha}-{\gamma}$ linkage. In our most recent study, simultaneous patch-clamp recordings from the soma and axon hillock revealed a spike-back-propagation from the spike-initiation site in the stem axon to the soma in response to a somatic current pulse. The persistent $Na^+$ current was found to be responsible for the spike-initiation in the stem axon, the activation threshold of which was lower than those of soma spikes. Somatic inputs or impulses arising from the sensory ending, whichever trigger spikes in the stem axon first, would be forwarded through the central axon to the target synapse. We also demonstrated that at hyperpolarized membrane potentials, 4-AP-sensitive $K^+$ current ($IK_{4-AP}$) exerts two opposing effects on spikes depending on their origins; the suppression of spike initiation by increasing the apparent electrotonic distance between the soma and the spike-initiation site, and the facilitation of axonal spike invasion at higher frequencies by decreasing the spike duration and the refractory period. Through this mechanism, the spindle activity caused by ${\gamma}-MNs$ would be safely forwarded to ${\alpha}-MNs$. Thus, soma spikes shaped differentially by this $IK_{4-AP}$ depending on their origins would reflect which one of the two inputs was forwarded to the target synapses.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.8B
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• pp.553-562
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• 2007

Consumer needs becomes various in a mature mobile telecommunication market, while service differentiation is hard to achieve. Because of the introduction of number portability, switching barrier becomes lower and the competition among telecommunication service providers is getting fierce in order to maintain and obtain customers. Moreover, HSDPA, which is a new telecommunication service, caused the intense marketing activity for the move to the next generation customers. Under these circumstances, brand equity can be a key to a long-term competitive edge for mobile phone service providers. However, there were few researches reporting the mobile telecommunication brand equity, and none of them analyzed if customer equity which particularly is developed at the CDMA market has an effect on HSDPA service. In this study, we identified the determinants of mobile telecommunication brand equity, which is focused on brand image, customer benefit, price, service quality, and marketing activity, and its influence on the HSDPA service subscription behavior. Finally, we suggested the strategic implication of brand management strategies for mobile phone service providers.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.6
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• pp.902-906
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• 2017

Objective: This study was conducted to characterize the behaviors and the body weight of suckling piglets in different social environments. Methods: Two groups of sows and suckling piglets housed either in individual farrowing crates in separate pens ($1.8{\times}2.4m$, the control group) or in groups of three sows with their piglets in farrowing crates in a large common enclosure ($5.4{\times}2.2m$, the treatment group) were observed with the aid of video technology for 9 consecutive hours on days 1, 2, and 3, after mixing. Results: Suckling, agonistic, and elimination behaviors of suckling piglets were significantly higher in the control group than in the treatment group. Inactive behavior was higher in the treatment group than in the control group. Most of the effects of the social environment on the suckling piglets seem to be the result of large reductions in behaviors and body weight for piglets switching from high activity to low activity. Moreover, suckling behavior and birth body weight were highly correlated with body weight at the end of the test. Conclusion: The social environment that resulted from mixing, thus, had significant effects on the behavior and body weight of suckling piglets, and behavioral characteristics, therefore, should be considered when making improvements to the husbandry and care methods used in swine production.

• Journal of Microbiology and Biotechnology
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• v.14 no.6
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• pp.1267-1274
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• 2004

Colostrum contains various kinds of cytokines including TGF-$\beta$ that has potent regulatory effects on cells of the immune system. We compared the levels of TGF-$\beta$1 and TGF-$\beta$2 in bovine and human colostrum. Based on the isoform-specific ELISA, bovine colostrum collected on day 1 post-delivery retained $53.71{\pm}29.55\;ng/ml$ of TGF-$\beta$1 and $40.41{\pm}21.78\;{\mu}g/ml$ of TGF-$\beta$2 (n=4), while in human, $381.45{\pm}158.24\;ng/ml$ of TGF-$\beta$1 and $41.47{\pm}9.63\;ng/ml$ of TGF-$\beta$2 (n=5). Thus, dominant TGF-$\beta$ isoforms were completely opposite between human and bovine colostrum samples. The concentrations of both isoforms declined as lactation proceeded. Biological activities of the colostrum samples were determined using an MV1LU cell line. Consistent with the result from the immunoassay, TGF-$\beta$1 in human and TGF-$\beta$2 in bovine colostrum were responsible for the anti proliferative activity against MV1LU cells. Furthermore, bovine colostrum increased IgA secretion by LPS-stimulated mesenteric lymph node (MLN) cells, and this effect was abrogated by either anti­TGF-$\beta$2 antibody or combined anti-TGF-$\beta$1/$\beta$2 antibody, but not by anti- TGF-$\beta$1 antibody alone. Similarly, TGF-$\beta$2 in bovine colostrum enhanced the Ig germ line (GL) promoter activity, which is the earliest event toward IgA isotype switching. Taken together, these results suggest that TGF-$\beta$ isoforms, differentially expressed in human and bovine colostrum, may promote IgA isotype production in the neonatal intestine.

• Journal of the Korea Society of Computer and Information
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• v.13 no.3
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• pp.225-236
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• 2008

This study is to evaluate the influence of relationship marketing and identify empirically the important factors which affect relationship continuity between multimodal transport operators and shippers. The empirical findings of this research are, MTO's marketing activity factors which consist of customers' contact intensity, relationship-oriented factors, positively affects relationship continuity such as revisit intention and word-of-mouth communication. As a result, relationship marketing activities are essential to the market strategy of MTO for continuous and stable growth. Also, on condition of transactional types, On-line transaction has an effect of customer switching, but there is no different effect in case of service type. Accordingly, international MTO in domestic need to develop various relationship marketing programs such as a special program for enhancing the continuity, an event for long-term customers and training program should be implemented and enforced to elevate qualify of the service encounter.

• Molecules and Cells
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• v.24 no.2
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• pp.283-287
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• 2007

$TGF-{\beta}1$ induces Ig germ-line ${\alpha}$ ($GL{\alpha}$) transcription and subsequent class switching recombination (CSR) to IgA. In the present study, we investigated the roles of two E3-ubiquitin ligases, Smurfs (HECT type) and Arkadia (RING finger type) on $TGF{\beta}1$-induced IgA CSR. We found that over-expression of Smurf1 and Smurf2 decreased $TGF{\beta}1$-induced $GL{\alpha}$ promoter activity and strengthened the inhibitory effect of Smad7 on the promoter activity. Further, over-expression of Smurf1 and Smurf2 decreased both Smad3/4-mediated and Runx3-mediated $GL{\alpha}$ promoter activities, suggesting that the Smurfs can down-regulate the major $TGF-{\beta}1$ signaling pathway and decrease $GL{\alpha}$ gene expression. In parallel, the over-expressed Smurf1 decreased the expression of endogenous IgA CSR-predictive transcripts ($GLT_{\alpha}$, $PST_{\alpha}$, and $CT_{\alpha}$) and also $TGF{\beta}1$-induced IgA secretion. Conversely over-expression of Arkadia abolished the inhibitory effect of Smad7 on $TGF{\beta}1$-induced $GLT_{\alpha}$ expression and IgA secretion. Similar results were obtained in the presence of over-expressed Smad7 and Smurf1. These results indicate that Arkadia can amplify $TGF{\beta}1$-induced IgA CSR by degrading Smad7, which interacts with Smurf1. We conclude that Smurf and Arkadia have opposite roles in the regulation of $TGF{\beta}1$-induced IgA isotype expression.

• Journal of Microbiology and Biotechnology
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• v.13 no.4
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• pp.598-606
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• 2003

Salmonella encodes an enterotoxin (Stn) which possesses biological activity similar to the cholera toxin. Stn contributes significantly to the overall virulence of S. typhimurium in a murine model. The production of Stn is enhanced in a high-osmolarity medium and by contact with epithelial cells. In the present study, the in vitro and in vivo transcriptional regulations of the sin promoter revealed two promoters, P1 and P2. The P1 promoter identified by a primer extension analysis of stn mRNA exhibited a switching mechanism in vivo. Depending on the growth stage, transcription was initiated from different start sites termed $P1_S\;and\;P1_E$. $P1_S$, recognized by RNA polymerase containing ${\sigma}^S(E{\sigma}^S),\;and\;P1_E$, recognized by $E{\sigma}^70$, were activated during the stationary and exponential phases, respectively, while $P1_S\;and\;P1_E$ were both negatively regulated by CRPㆍcAMP and H-NS. Results revealed that $P1_S$ was the responsible promoter activated under a high osmolarity and low pH. The P2 promoter was identified 45 nucleotides downstream from $P1_E$ and negatively controlled by CRPㆍcAMP in vitro. No P2 activity was detected in vivo. The regulation of stn expression monitored using a Pstn::egfp fusion indicated that $E{\sigma}^S$ was required for the induction of stn and various factors were involved in stn regulation inside animal cells.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.3
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• pp.95-99
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• 2008

This paper proposes a new minimal resource high-level synthesis algorithm for low power design automation. The proposed algorithm executes an efficient approach to minimize the power consumption of the functional units in a circuit during the high level synthesis. In this paper, we visit all control steps one by one to reduce the switching activity in CDFG. The register sharing algorithm determines the minimum register after the life time analysis of all variable. According to property of input signal for functional unit, the proposed method visits all control step one by one and determines the resource allocation with minimal power consumption at each control step in a greedy fashion. The effect of the proposed algorithm has been proved through various filter benchmark to adopt a new scheduling and allocation algorithm considering the low rover.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.35.1-35.1
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• 2013

By probing nuclear regions and overall properties of AGN hosts as a function of their environments, we aim to observationally examine how AGN activities are related to their surroundings. We have selected eight representative AGN hosts in the Virgo cluster, including seven cluster members (M49, M60, M84, M87, NGC 4435, NGC 4526, NGC 4636) and one galaxy that is likely to be background (NGC 4261) but still close enough to be studied in high resolution. The selected galaxies are located in a range of density regions showing various morphology in 1.4 GHz continuum. High resolution observations with the KVN allow us to access the inner region of the AGN without suffering from dust extinction and synchrotron self-absorption. Since half of our targets are weak to be detected at K-band within its coherence time, we applied phase referencing (fast antenna position switching) to calibrate fast atmospheric phase fluctuations. We successfully detected relatively bright AGNs, such as M87, M84 and NGC4261, but no detection signature was found to the other members of the sample. In this talk, we will present our first results from our KVN observations, while we will discuss in detail the applied technique and our immediate future plans.