• Journal of Korean Society on Water Environment
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• v.22 no.2
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• pp.364-369
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• 2006

The investigation of the Acetylcholinesterase (AChE) activity in tissues (brain, eye, muscle and serum) of crucian carp (Carassius auratus) exposed to the waterborne parathion was carried out for application as biomarker of organophosphate pesticides. The AChE activities were significantly inhibited in the experimental organs of C. auratus treated ${\geq}63{\mu}g/L$ of concentrations of parathion. The AChE activity of C. auratus was significantly reduced in response to brain (79.1~92.4%), eye (76.0~91.5%), muscle (89.7~97.6%) and serum (68.9~78.0%) after 30 days exposure. No significant mortality occurred during the experiment duration but behavioral changes occurred in the carp after exposure to the parathion were erratic swimming and convulsions. The anomaly in the carp exposed to parathion were observed in the form of scoliosis. The use of AChE activity and other adverse responses of the carp might be use as a reliable monitoring tool to detect parathion in aquatic ecosystem which might produce significant population changes.

• Journal of Microbiology and Biotechnology
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• v.32 no.4
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• pp.447-457
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• 2022

Notoginsenoside R1 and ginsenoside Rg1 are the main active ingredients of Panax notoginseng, exhibiting anti-fatigue, anti-tumor, anti-inflammatory, and other activities. In a previous study, a GH39 β-xylosidase Xln-DT was responsible for the bioconversion of saponin, a natural active substance with a xylose group, with high selectivity for cleaving the outer xylose moiety of notoginsenoside R1 at the C-6 position, producing ginsenoside Rg1 with potent anti-fatigue activity. The optimal bioconversion temperature, pH, and enzyme dosage were obtained by optimizing the transformation conditions. Under optimal conditions (pH 6.0, 75℃, enzyme dosage 1.0 U/ml), 1.0 g/l of notoginsenoside R1 was converted into 0.86 g/l of ginsenoside Rg1 within 30 min, with a molar conversion rate of approximately 100%. Furthermore, the in vivo anti-fatigue activity of notoginsenoside R1 and ginsenoside Rg1 were compared using a suitable rat model. Compared with the control group, the forced swimming time to exhaustion was prolonged in mice by 17.3% in the Rg1 high group (20 mg/kg·d). Additionally, the levels of hepatic glycogen (69.9-83.3% increase) and muscle glycogen (36.9-93.6% increase) were increased. In the Rg1 group, hemoglobin levels were also distinctly increased by treatment concentrations. Our findings indicate that treatment with ginsenoside Rg1 enhances the anti-fatigue effects. In this study, we reveal a GH39 β-xylosidase displaying excellent hydrolytic activity to produce ginsenoside Rg1 in the pharmaceutical and food industries.

• Archives of Plastic Surgery
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• v.36 no.4
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• pp.437-444
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• 2009

Purpose: Transgender is a disorder of gender identity, who have appropriate chromosomal, hormonal and anatomical characteristics corresponding to their sexual phenotype but feel strongly with respect to their sexual identity, that they belong to the opposite sex. There is a persistence discomfort and sense of inappropriateness about one's assigned sex in a person who has reached puberty. Transgender is a psychiatric problem, but surgical method provides more satisfactory adjustment for patients. In gender reassignment surgery for female to male transgender, mastectomy, nipple reduction, hysterectomy, oophorectomy and phalloplasty are included. And as the final operation, recommended for scrotoplasty and artificial testes insertion. So we investigated the necessity and method of scrotoplasty in the final operation of female to male transgender. Method: The authors have long term follow-up of 75 cases female to male transgender during January, 1991 to February, 2008. Among them, 13 cases were evaluated in this study. During phalloplasty, the labium major skin preserved. And this labium majoral skin flap was made for the neoscrotum. At least six months later, artificial testes were inserted in neoscrotum with local anesthesia. Middle sized (3 cm diameter) artificial testes(silicon gel or carving soft silicone implant) were used because of the limitation of the neoscrotum. We evaluated the questionnaire and interview about the postoperative satisfaction in configuration of reconstructed scrotum, and the necessity of operation, the postoperative psychosocioeconomic improvement and limitation of body exposure activities such as swimming, public bathing. Results: Based on this study, satisfaction of reconstructed scrotum after scrotoplasty was improved(92%). The necessity of scrotoplasty was in 92.3% and the postoperative psychosocioeconomic well - being improvement was 77% in answers. Less limitation of activities requiring body exposure was 54% in answers. Most of the patients were satisfied with the results of surgical operation inspite of the operative procedure had some postoperative complications. Conclusion: This study was reported that the scrotoplasty in female to male transgender is not only a conversion of external genitalia but also an improvement of psychosocial state. Most patients sincerely hope to this operation, so we improve our surgical method for more good results.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5060-5065
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• 2012

The purpose of this study was to report the incidence of drowning accident in order to prevent and decrease the accidents of drowning. Data were obtained on all accidents of drowning accidents occurred from January to December 2007 were identified by using the Emergency Activity Daily Report Data from the National Emergency Management Agency (NEMA). The age, weather, date, location, time and case of the drowning accident were examined. The Chi-square test was used to compare each group. All comparisons were made at the p<0.05 level of significance. The result show that the age of drowning accidents for victims aged 20-29 was 27.9%, and for victims aged 30-39 years, 18.7%. In reguard to the age group, drowning accidents during recreational aquatic activity was age 20-39; 51(44.8%). In reguard to the locations, the number of drowning accidents in a lake or reservoir during recreational aquatic activity was 62(53.4%). The number of drowning accidents in a lake or reservoir during etc was 51(58%). In reguard to the days, the number of drowning accidents on Saturday during recreational aquatic activity was 30(25.8%), on Sunday 32(27.6%). The weather of drowning accidents during recreational aquatic activity was sunny 60(51.8%), rainy 40(34.4%), cloudy 16(13.8%). The season of drowning accidents during recreational aquatic activity was summer 53(45.7%). In reguard to season, two groups are significantly different. Drowning is a leading cause of injury related accidents. Understanding the characteristics of drowning is the first step to developing prevention strategies that may be beneficial for people of all ages and under nearly all circumstances are increased swimming ability, lifeguard staffing, providing life jackets, and public education activities.

• Journal of the Korean Institute of Landscape Architecture
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• v.46 no.1
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• pp.127-142
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• 2018

Ttukseom was once a suburban area that had a government horse ranch for national use and a naenogpo (area of royal farm land). During the Japanese colonial period, a pleasure ground was built at Ttukseom, and after independence, it has been used as a park through the process of urbanization. This study examines the creation of the Ttukseom Pleasure Ground and the process through which the pleasure ground were transformed to a park. This study also explores its landscape and cultural aspects. In the 1930s, Gyeongseonggwedo (京城軌道), a private railway company, built a pleasure ground at Ttukseom to attract passengers, according to the business model of Japanese railway companies, in which recreational areas were developed near railway routes. Mass media portrayed this area as a "rural landscape" in contrast to the city. The Ttukseom Pleasure Ground emerged as a popular summer resort for Gyeongseong citizens. At the same time, it was managed by Gyeongseongbu (京城府). The city of Seoul began to manage the Ttukseom Pleasure Ground following independence, and development plans for Ttukseom as a pleasure ground or a park were continuously drafted but never implemented. Even after Korea's independence, the operation and use of the pleasure ground did not change significantly from the colonial era. In the late 1980s, the Ttukseom Pleasure Ground became the Ttukseom Han River Citizen's Park, and the sandy beach of the Han River was removed. Nonetheless, the previous facilities and major activities such as an open-air swimming pool, camp ground, and areas for boat recreation remained as major park programs. When the urbanization of Ttukseom was completed, its idyllic image disappeared and it became a park instead of a pleasure ground. Since parks expand their programs, it can be concluded that by providing those kinds of programs, the Ttukseom Pleasure Ground transformed to a park.

• Korean Journal of Environmental Biology
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• v.35 no.2
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• pp.128-133
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• 2017

To determine the optimum water temperature (a temperature which minimizes metabolic activities and stress in fish) for long distance transportation of red-spotted grouper (Epinephelus akaara), by evaluating the behavior, survival and physiological and hematological responses to variable water temperature conditions (9, 12, 15, 18 and $21^{\circ}C$) for 48 hours. Fish exposed to $9^{\circ}C$ died at 48 hours exposure, but those exposed to 12, 15, 18 and $21^{\circ}C$ treatment groups all survived. Fish in the 15, 18 and $21^{\circ}C$ exposure groups exhibited normal swimming, while those exposed to $12^{\circ}C$ were observed to be stationary at the bottom of the tank. The plasma cortisol and glucose concentration were higher in fish exposed to $12^{\circ}C$ than at other temperature conditions. The fish in the 12 and $15^{\circ}C$ groups had significantly higher hematocrit (Ht) and hemoglobin (Hb) than those in the 18 and $21^{\circ}C$ groups (P<0.05). Levels of aspartate aminotransferase (AST), $NH_3$ and osmolality showed a pattern similar to the levels of plasma cortisol, while alanine aminotransferase (ALT) and total protein did not significantly vary among the experimental groups. These results indicate that the optimum water temperature for long distance transportation of the red-spotted grouper is $15^{\circ}C$.

• The Journal of the Korea Contents Association
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• v.17 no.7
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• pp.283-293
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• 2017

This study analyzed the actual conditions of use of public sports facilities and characteristics of the users of the facilities through surveys and measured the spatial imbalance of the public sports facilities currently supplied by using gravity potential model. This study also suggests evaluation criteria that may be considered for efficient location selection by examining the change of accessibility to the facilities that meet the needs of users in the future. As the results of the questionnaire survey, unlike current usage, the users hoped for badminton, weight training and swimming. And we could confirm the demand for the expansion of the multi - purpose indoor gym which can carry out such activities in the areas. As the result of the analysis on the difference in accessibility of the public sports facility, there were some large variations in the regions. It was found that a balanced supply of facilities was needed in terms of equity. In particular, when analyzing by considering the population estimates of 2025, It is analyzed that the accessibility will be reduced to about 60% compared to that of 2015. In addition, it is evaluated as the best alternative in terms of overall efficiency that the location of the facilities should be in Munsan area where population growth is expected in the future.

• Korean Journal of Ichthyology
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• v.28 no.2
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• pp.110-115
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• 2016

This study was conducted in order to investigate the growth and morphological development of Cypselurus hiraii larvae and to obtain basic data for taxonomic research. Specimens for this study were collected using a scoop net (aperture Ø60 cm) at the Geomun Island in Yeosu-si, Jollanam-do in July and August of 2013, and the mean water temperature was $20.6{\pm}1.84^{\circ}C$ and the mean salinity was $32.1{\pm}0.46$‰ during the collection. In post-larvae of total length 9.58~9.69 mm (average $9.63{\pm}0.04mm$, n=5), the mouth was opened, and the maxilla was shorter than the mandible. The length of the dorsal fin did not exceed that of the ventral fin, and the dorsal fin was on the same line as that of the ventral fin. In post-larvae of total length 18.0~18.5 mm (average $18.2{\pm}0.22mm$, n=5), with the growth accelerated, the pectoral fin was developed broadly and their caudal fin was differentiated into the heterocercal tail. These characteristics suggest the development of swimming ability and resultant active feeding activities. In post-larvae of total length 22.4~23.0 mm (average $22.7{\pm}0.21mm$, n=5), striped melanophores deposited in the pectoral fin, and small spot-like melanophores expanded in the processes formed on the mandible. The dorsal and anal fins were on the same line, and the anal fin was situated behind the dorsal fin.

• Journal of muscle and joint health
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• v.9 no.1
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• pp.18-27
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• 2002

Introduction : Exercise has been suggested as an important nursing strategy in which to help elderly maintain functional performance and to enhanced quality of life. Most of exercise study has been reported on fitness exercise such as walking, swimming, dance etc for health of elderly. There have been few reports about exercise on the promotion of small and fine movement of elderly. The purpose of this pilot study was to determine an effect of 6 weeks hand and finger exercise in home to improve hand muscle strength such as grip strength and finger pinch pressure. Materials and Methods Design: This pilot study was used one group pre and post-test design. Sample: Twelve elderly women above 60 years of age or older living in community were selected by convenient sampling. Procedure: Signed informed consent was obtained prior to participate in this study. The authors met elderly and taught hand and finger exercise, daily a week for 6 weeks, within 30 minutes per session. But exercise frequency and strength were not same. Instruments: Left and right grip strength were measured by Bulb Dynamometer(made in USA) and left and right pinch pressure were measured by Baseline Hydraulic Pinch Gauge(made in USA). Data analysis: Discriptive data analyses were performed on all variables. Wilcoxon matched-pairs Signed-Ranks test were used to find difference of grip strength and pinch pressure between pre and post exercise using SPSS 10.0 for Window. Results: Samples age ranged from 60 to 73, Mean age was 65.3. All were women. Ten elderly were diagnosed osteoarthritis and one had DM. After six weeks hand and finger exercise, Left and right grip strength were higher than those of before exercise(Z=-2.667, P<0.01 ; Z=-3.065, p<0.01). And left pinch pressure after hand and linger exercise were higher than that of before pinch pressure (Z=-2.315, p<0.05). But Right pinch pressure was not shown significant change(Z=-1.099, p>0.05). Conclusions: Although this study was limited by the sample size and design, the findings provide some important implications for community based exercise nursing intervention. Short term (six weeks) exercise of hand and linger is shown to be useful as nursing intervention to maintain routine daily activities such as eating, writing, grip something for elderly.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.35 no.6
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• pp.551-556
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• 2002

We have experimentally evaluated the content of thyroid hormones (THs), the growth and activity of larval rockfish (Sebastes schiegeli) born from parturient mother fish injected with 20 $\mu$g/g BW of 3,5,3-triiodo-L-thyronine ($T_{3}$). There was no difference of L-thyroxine ($T_{4}$) levels between controls (sham control and control) and $T_{3}$ groups in yolk-sac larvae just born from broodstock, while $T_{3}$level of $T_{3}$ group was significantly increased compared with controls. In addition, the both larval $T_{3}$ and $T_{4}$ levels in $T_{3}$ group were always higher than those of control during experimental period. Also, there were significant differences in the development of larvae from the two groups. The larval growth in total length and body weight according to the elapsed days after parturition showed the linear and curve equations, respectively, and the slopes of $T_{3}$ group were significantly higher than those of control. The survival rate of larvae in $T_{3}$ group was higher than that of control. Although the survival rate in $T_{3}$ group under the condition of starvation was significantly depressed compared with the control, larval swimming index in $T_{3}$ group was higher than control. Finally, these findings suggest that the exogenous $T_{3}$ could be transferred into hatched larvae in parturient rockfish by maternal injection, and subsequently the exogenous hormone could play some roles on physiological metabolism of larvae after parturition and may confer a distinct advantage to the fragile larvae during the early developmental stage.