• 청정기술
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• 제17권1호
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• pp.13-18
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• 2011

포스핀(phosphine) 리간드(ligand)가 도포된 메조포러스 실리카(mesoporous silicas)에 팔라듐 나노입자를 도입하여 새로운 팔라듐(Pd) 불균일 촉매(heterogeneous catalyst)를 제조하였다. 제조된 촉매는 브롬화벤젠 유도체(bromobenzene derivatives)들의 Suzuki cross-coupling 반응에 대하여 뛰어난 촉매활성을 나타내었고 촉매를 두 번째 사용하였을 때는 수율이 감소하였다.

• Bulletin of the Korean Chemical Society
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• 제24권11호
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• pp.1632-1636
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• 2003

Palladium-catalyzed cross-coupling reactions of neopentyloxysulfonylphenyl bromides with arylboronic acids provided a variety of neopentyl biphenylsulfonates in good yields. 2-Bromo- and 4-bromobenzenesulfonates underwent the coupling reaction more rapidly than 3-bromobenzenesulfonate, while chlorobenzenesulfonate did not produce the coupling product under the standard reaction conditions.

• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2697-2700
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• 2009

A $Pd(OAc)_2/(o-MeOPh)_3P$ system has been developed for the catalytic Suzuki coupling of aryl bromides with arylboronic acids. Our catalyst system covers a broad spectrum of commonly available arylboronic acids and aryl bromides to provide biaryls in very good yields. The catalyst system works very well in the synthesis of sterically hindered biaryls.

• Bulletin of the Korean Chemical Society
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• 제34권5호
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• pp.1477-1480
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• 2013

The Suzuki cross-coupling reactions proceeded in excellent yields when it was catalyzed by magnetically recyclable nanocatalyst. This nanocatalyst provided very high catalytic activity with low loading level (1 mol %), because the palladium nanoparticles were so small in size (~2 nm) and located on the surface of the nanocomposite. It was also easily recovered from the reaction mixture using a magnet and reused for six consecutive cycles.

• Bulletin of the Korean Chemical Society
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• 제25권1호
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• pp.29-30
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• 2004

• 대한화학회지
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• 제61권5호
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• pp.299-303
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• 2017

• 대한화학회지
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• 제66권6호
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• pp.442-450
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• 2022

생리학적 활성을 보일 것으로 기대되는 다양한 pyrrolopyrimidine 유도체를 O-arylation과 Suzuki 짝지움 반응을 통해 합성하였다. 금속 촉매 Cu를 사용하고 마이크로파 조사 조건에서O-arylation을 성공적으로 진행하여 pyrrolo[3,2-d]pyrimidine의 4번 위치에 phenol기를 도입할 수 있었다. 또한, 금속촉매 Pd를 사용하는 Suzuki짝지움 반응도 마이크로파를 사용하여 pyrrolo[3,2-d]pyrimidine의 4번 위치에 aryl 기를 도입할 수 있었다. 유도체의 다양화를 위한 반응 조건으로 마이크로파를 사용함으로써 긴 반응 시간과 열전달 효율성 문제를 가지고 있는 전통적인 열 반응의 단점을 획기적으로 극복할 수 있었다. 본 연구 결과는 신약개발 연구에 중요한 역할을 할 것으로 기대되는 pyrrolo[3,2-d]pyrimidine 유도체를 다양화하는데 사용할 수 있다.

• 약학회지
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• 제57권5호
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• pp.357-361
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• 2013

A formal synthesis of Lespedezol $A_1$ has been accomplished. The key feature of this synthesis involves an efficient and powerful palladium-catalyzed cross coupling reaction of diazocarbonyl compound with bis(benzyloxy)phenylboronic acid for the key 3-aryl-chromen-4-one intermediate, which was difficult to be prepared by Suzuki coupling reaction in the previous study. The versatile and efficient synthetic procedure would facilitate synthesis of pterocarpenes and their derivatives.

• Bulletin of the Korean Chemical Society
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• 제32권spc8호
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• pp.2897-2898
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• 2011

• Bulletin of the Korean Chemical Society
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• 제32권8호
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• pp.2584-2592
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• 2011

Nickel nanoparticle-poly(N-vinyl-2-pyrrolidone)/$TiO_2-ZrO_2$ composite (Ni-PVP/$TiO_2-ZrO_2$) was prepared by in situ polymerization method. The physical and chemical properties of Ni-PVP/$TiO_2-ZrO_2$ were investigated by XRD, FT-IR, BET, TGA, SEM and TEM techniques. The catalytic performance of this novel heterogeneous catalyst was determined for the Suzuki-Miyaura cross-coupling reaction between aryl halides and phenylboronic acid in the presence of methanol-water mixture as solvent. The effects of reaction temperature, the amount of catalyst, amount of support, solvent, and amount of metal for the synthesis of Ni-PVP/$TiO_2-ZrO_2$, were investigated as well as recyclability of the heterogeneous composite. The catalyst used for this synthetically useful transformation showed considerable level of reusability besides very good activity.