• Title/Summary/Keyword: Survival Rates

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Studies on the Effects of Bisection Method and With and Without-Zona Pellucida of Bovine Embryos on In Vitro Developmental Rates (분할방법 및 투명대 부착 여부가 분할 초기배의 체외발생에 미치는 영향에 관한 연구)

  • 이종진;남윤이;김상근
    • Journal of Embryo Transfer
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    • v.12 no.1
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    • pp.21-27
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    • 1997
  • The studies were carried out to investigate the effects of bisection method and with and without-zona pellucida of embryos on in vitro developmental rate bisected embryos by micromanipulator, micropipette and pipetting. The ovaries were obtained from slaughtered Korean native cows. The follicular oocytes were cultured in TCM-199 mediurn containing 10 IU /ml의 PMSG(Sigma, USA), 10 IU /ml의 hCG, 1$\mu$g /ml의 $\beta$-estradiol(Sigma, USA) and 10% FCS for 24~48 hrs in incubator with 5% $CO_2$ in air at 38.5$^{\circ}C$ and then, matured oocytes were again cultured for 12~ 18 hrs with motile capacitated sperm by preincubation of heparin. Bisected embryos cultured for 1~5 days in 20% FCS + TCM-199 medium. Survival rate was defined as developmental rate on in vitro culture or FDA-test. The results are summarized as follows :1. The survival rates of bisected bovine embryos by micromanipulator and micropipett were 29.2% and 19.1%, respectively. The rates of non-bisection embryos(46.7%) were significantly higher than those of bisection embryos. 2. The in vitro developmental rates of bisected bovine embryos by micromanipulator, micropipett and pipetting method were 32.4%, 19.4% and 25.6%, respectively.3. The in vitro developmental rates of with and without-zona pellucida of bisected bovine embryos by raicromanipulator were 30.8% and 25.0%, respectively. The rates of nonbisection embryos(53.1%) were significantly higher than those of bisection embryos.

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Graft Patency of No-Touch Saphenous Veins Used as Aortocoronary Bypass Grafts

  • Jeongwon Kim;Suk Ho Sohn;Jae-Sung Choi;Se Jin Oh;Ho Young Hwang
    • Journal of Chest Surgery
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    • v.56 no.5
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    • pp.313-321
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    • 2023
  • Background: This study evaluated the early, 1-year, and 3-year graft patency rates and mid-term clinical outcomes after no-touch saphenous veins (NT-SVs) were used as aortocoronary grafts in coronary artery bypass grafting (CABG). Methods: In total, 101 patients who underwent CABG using NT-SVs as aortocoronary grafts were included. The 2 most common indications for performing aortocoronary grafting with NT-SVs were unavailability of the left internal thoracic artery (n=36) and moderate lesions where flow competition was expected (n=27). Early (median, 1 day; interquartile range [IQR], 1-2 days), 1-year (median, 13 months; IQR, 11-16 months), and 3-year (median, 34 months; IQR, 27-41 months) graft angiography was performed in 98 (97.0%), 84 (83.2%), and 40 patients (39.6%), respectively. The median follow-up duration was 43 months (IQR, 13-76 months). Overall survival rates and the cumulative incidence of major adverse cardiac events were evaluated. Results: The operative mortality rate was 2% (2 of 101 patients). Early postoperative patency rates for overall and aortocoronary NT-SV grafts were 98.2% (223 of 227 distal anastomoses) and 98.2% (164 of 167), respectively. The 1- and 3-year patency rates for aortocoronary SV grafts were 94.9% (131 of 138) and 90.6% (58 of 64), respectively. The overall survival rates at 5 and 10 years were 81.7% and 59%, respectively. The cumulative incidence of major adverse cardiac events at 5 and 10 postoperative years was 20.7% and 39%, respectively. Conclusion: The feasibility of using NT-SVs as aortocoronary grafts in CABG was shown in this study, based on the graft patency rates up to 3 years and the mid-term clinical outcomes.

Retrospective study on survival rate of 2158 osseointegrated implants placed in 770 patients in Sanbon dental hospital of Wonkwang University (원광대학교 산본치과병원에서 770명의 환자에 식립한 2158개의 골유착성 임플란트의 보철 전 초기 생존율에 관한 후향적 연구)

  • Seon, Hwa-Gyeong;Chee, Young-Deok
    • Journal of Dental Rehabilitation and Applied Science
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    • v.30 no.4
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    • pp.278-288
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    • 2014
  • Purpose: The aim of the study was to evaluate preprosthetic initial survival rate and factors associated with survival of osseointegrated implants placed in edentulous area of maxilla and mandible and to suspect the possible causes leading to failure. Materials and Methods: A total of 2158 endosseous implants that had been inserted between 2004 through 2013 were placed in 770 patients. The clinical comparisons were performed to evaluate implant loss in relation to age and gender of patients, position, system, length and diameter of implant, and bone graft technique. Results: According to position, the survival rates were 98.23% in maxillary anterior site, 96.98% in maxillary posterior site, 97.85% in mandibular anterior site and 98.76% in mandibular posterior site (P < 0.05). According to diameter of implant, the survival rates were 100% under 3.0 mm, 97.09% between 3.0 to 3.5 mm, 98.19% between 3.5 to 4.0 mm and 98.29% between 4.0 to 4.5 mm but relatively lower survival rate was 75% in 5.0 mm-over (P < 0.05). The survival rates of implants were 89.51%, 98.28%, 98.34% and 99.27% in the group with isolated sinus graft, with isolated GBR, with sinus graft and GBR simultaneously and without bone graft, especially (P < 0.05). Conclusion: This study establishes a relationship between survival rate of implant and position, diameter of implant system and bone graft technique. In conclusion, there were low survival rates in maxillary posterior site, in dental implants with wide diameter of 5 mm-over, and in the group with isolated sinus graft.

Differences in Incidence, Mortality and Survival of Breast Cancer by Regions and Countries in Asia and Contributing Factors

  • Kim, Yeonju;Yoo, Keun-Young;Goodman, Marc T
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2857-2870
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    • 2015
  • Although the incidence of breast cancer in Asia remains lower than in North America, Western Europe, and Oceania, rates have been increasing rapidly during the past few decades, and Asian countries now account for 40% of breast cancer cases diagnosed worldwide. Breast cancer mortality has also increased among Asian women, in contrast to decreased mortality in Northern America, Western Europe, and Oceania. These increased rates are associated with higher prevalence of breast cancer risk factors (e.g., reduced parity, delayed childbirth, increased obesity) that have accompanied economic development throughout the region. However, Asian regions (western, south-central, south-eastern, and eastern) and countries differ in the types and magnitude of changes in breast cancer risk factors, and cannot be viewed as a single homogeneous group. The objective of this paper was to contrast the heterogeneous epidemiology of breast cancer by Asian regions and countries, and to suggest potential avenues for future research.

White Spot Baculovirus Infection of Shrimp Spawner, Inhabitant Organisms and Survival in Seawater (White Spot Baculovirus의 모하와 중간숙주 감염 및 해수생존)

  • Heo, Moon-Soo;Sohn, Sang-Gyu;Kim, Young-Jin
    • Journal of fish pathology
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    • v.13 no.1
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    • pp.15-20
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    • 2000
  • Infection rates with white spot baculovirus(WSBV) in wild-caught shrimp spawners appeared to be 52% in Penaeus chinensis and 20% in Penaeus japonicus when diagnosed by polymerase chain reaction (PCR). Infection rates of WSBV from inhabitant organisms in shrimp farm showed 37% in Upogebia major and 29% in Calliamassa japonica. The viruses maintained their survivorship in seawater at $4^{\circ}C$, but lost it at $25^{\circ}C$.

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The Experimental Effects of ShingongNaetakSan Extract on Immunocytes and Cancer (神功內托散이 免疫細胞 및 腫瘍에 미치는 實驗的 效果)

  • Choi, Jung-hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.13 no.1
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    • pp.129-140
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    • 2000
  • ShingongNaetakSan(SNS) was drugs used in treatment of carbuncle and cellulitis in Oriental So, the purpose of this Study was to investigate effect of SNS on the proliferation of immunocytes and anti-cancer. This Study estimated the proliferation of L1210 cell lines and S-180 cell lines in vitro. and estimated the proliferation of L1210 cells, thymocytes and splenocytes, and tumor weight, body weight and mean survival rates in vivo. The proliferation and cytotoxicity of cells was tested using a colorimetric tetrazoliun assy(MTT assy). The results of this study were obtained as follow ; SNS had effect on the proliferation of L1210 cells in vitro and splenocytes in vivo, and SNS decreased significantly tumor weight, and increased significantly mean survival rates.

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Radioprotective Effects of Ginseng Proteins (인삼단백질의 방사선 방어작용)

  • 김춘미;한규선
    • YAKHAK HOEJI
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    • v.29 no.5
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    • pp.246-252
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    • 1985
  • Ginseng proteins were isolated and partially purified to obtain two fractions, namely GI and GII. Radioprotective effects of these fractions were examined on $\gamma$-ray irradiated ICR mice by observing 30-day survival rates after irradiation. Also investigated were the effects of GI fraction on the recovery of radiation damage. As the results, the GI fraction showed strong protection against radiation indicated by the increment of 30-day survival rates, while the GII fraction did not. The GI fraction enhanced the recovery of body and splenic weights and increased the amount of DNA in liver significantly. It also helped to recover the damage done on erythrocytes by increasing the number to normal in short period, however, it had no effect on the recovery of leukocyte counts.

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Yeast Cell Cultivation of Produce Active Dry Yeast with Improved Viability (생존능이 증진된 활성 건조효모 생산을 위한 효모세포배양)

  • Kim, Geun;Kim, Jae-Yun
    • KSBB Journal
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    • v.14 no.5
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    • pp.561-565
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    • 1999
  • Optimum conditions for vacuum-drying ad cultivation of yeast cells for the production of active dry yeast were examined. At lower temperature, more drying time was required to dry the yeast pellet to reach the desirable water content(8%). Optimum temperature of vaccum oven and time for drying was 63$^{\circ}C$ and 90 min, respectively. Optimum medium composition for flask culture using cane molasses as the substrate were 0.25% sugar, 0.013% $K_2$HPO$_4$, 0.1% $K_2$HPO$_4$. and 0.125% (NH$_4$)$_2$SO$_4$. Culture temperature $25^{\circ}C$ gave the highest survival rate of dired yeast. After finishing fed-batch culture and the culture was left in the fermentor without adding any sugar or nutrient, survival of the dried yeast harvested from the fermentor increased to 86.0% after 36 hr. It was also observed that the yeast cells with higher budding rates showed lower survival rate.

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Radiotherapy Results of Brain Astrocytomas (성상세포종의 방사선치료성적)

  • Suh, Chang-Ok;Kim, Gwi-Eon;Suh, Jung-Ho
    • Radiation Oncology Journal
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    • v.2 no.2
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    • pp.177-184
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    • 1984
  • A retrospective analysis of survival data of i2 cases with brain astrocytomas was presented. All patients received post·operative radiotherapy in the period of $1973\~1983$ at YUMC, Yonsei Cancer Center. There were 24 patients with Grade II, 12 patients with Grade III and 16 patients with Grade IV astrocytomas. Survival rates o ere analyzed according to histologic grade of malignancy, age, tumor location, radiation dose and extent of surgical tumor resection. 5year actuarial survival for patients with Grade II astrocytomas was $32.9\%$ and Grade III was $42.9\%$. The 1 year and 2 year survival rate of Grade astrocytomas were $46.7\%$ and $0\%$. Histologic grade of tumor was important prognostic factor in brain astrocytomas. Age and extent of surgical resection were significant prognostic (actors in all grades of astrocytomas and tumor location and radiation dose were significant in Grade f astrocytomas.

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Beta Processes and Survival Analysis (베타과정과 베이지안 생존분석)

  • Kim, Yongdai;Chae, Minwoo
    • The Korean Journal of Applied Statistics
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    • v.27 no.6
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    • pp.891-907
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    • 2014
  • This article is concerned with one of the most important prior distributions for Bayesian analysis of survival and event history data, called Beta processes, proposed in Hjort (1990). We review the current state of the art of beta processes and their application to survival analysis. Relevant methodological and practical areas of research that we touch on relate to constructions, posterior distributions, large-sample properties, Bayesian computations, and mixtures of Beta processes.