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Anti-Obesity Effect of Panax Ginseng in Animal Models: Study Protocol for a Systematic Review and Meta-Analysis (동물실험에서 인삼의 항비만 효과: 체계적 고찰과 메타분석을 위한 연구 프로토콜)

  • Cho, Jae-Heung;Kim, Koh-Woon;Park, Hye-Sung;Yoon, Ye-Ji;Song, Mi-Yeon
    • Journal of Korean Medicine for Obesity Research
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    • v.17 no.1
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    • pp.37-45
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    • 2017
  • Recently the global epidemic problem of obesity has stimulated intense interest in the study of physiological mechanisms using animal models as a way to gain crucial data required for translation to human studies. Panax ginseng has been reported to have anti-obesity or antidiabetic effects in many animal studies; however, there have been few studies investigating human obesity. Herein, we will assess and examine the evidence supporting the anti-obesity effect of Panax ginseng in animal models with respect to anthropometric and metabolic outcomes. We will include controlled, comparative studies assessing the effect of Panax ginseng in preclinical studies of obesity. Panax ginseng will be administered during or following the induction of experimental obesity. The primary outcome measure will be anthropometric assessment and the secondary outcome measures will include adipose tissue weight, total amount of food consumed and metabolic parameters. We will search MEDLINE, Embase, PubMed, Web of Science, and Scopus without language, publication date, or other restrictions. Ethical approval will not be necessary as the data collected in this study will not be individual patient data, consequently there will be no concerns about violations of privacy. After finishing the whole procedure, the results will be disseminated by publication in a peer-reviewed journal or presented at a relevant conference. This protocol has been registered on the Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies (CAMARADES) website (http://www.camarades.info).

Preparation of Whey Powder-Based Biopolymer Films (유청분말을 이용한 생고분자 필름의 제조)

  • Cho, Seung-Yong;Park, Jang-Woo;Rhee, Chul
    • Korean Journal of Food Science and Technology
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    • v.30 no.6
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    • pp.1285-1294
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    • 1998
  • Whey powder, a by-product of milk industry, was utilized to produce biopolymer film with the combination of film matrix supporting material, sodium caseinate. Biopolymer films were prepared from whey powder-sodium caseinate mixtures at several mixing ratios. The effects of pH, plasticizers and cross-linkers on tensile strength (TS) and elongation (E) of films were investigated. The films could be formed by use of whey powder up to 70%. As the whey powder content was increased, TS of the film decreased while E increased. Films containing more than 70% of whey powder could not be formed due to the stickiness of lactose in whey powder. The optimum pH of the film solution was found to be 10. Among the plasticizers tested, sorbitol was found to be the most effective plasticizer while glycerol was inadequate for the film. Tensile strengths of films containing $30{\sim}40%$ whey powder were higher than 10 MPa with relatively high E, when the films were plasticized with 30% (w/w) and 40% sorbitol. TSs of the relatively weak films containing $50{\sim}60%$ whey powders were improved by the addition of small amount of sodium citrate for 30% sorbitol plasticized films, and by the addition of sodium chloride for 40% sorbitol plasticized films. It was concluded that up to 70% of whey powder could be utilized to produce biopolymer films by adding sorbitol and cross linkers at pH 10.

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In-Situ based Trajectory Editing Method of a 3D Object for Digilog Book Authoring (디지로그 북 저작을 위한 3D 객체의 In-Situ 기반의 이동 궤적 편집 기법)

  • Ha, Tae-Jin;Woo, Woon-Tack
    • Journal of the HCI Society of Korea
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    • v.5 no.2
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    • pp.15-24
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    • 2010
  • A Digilog Book is an augmented reality (AR) based next generation publication supporting both sentimental analog emotions and digitized multi-sensory feedbacks by combining a conventional printed book and digital contents. As a Digilog Book authoring software, ARtalet provides an intuitive authoring environment through 3D user interface in AR environment. In this paper, we suggest ARtalet authoring environment based trajectory editing method to generate and manipulate a movement path of an augmented 3D object on the Digilog Book. Specifically, the translation points of the 3D manipulation prop is examined to determine that the point is a proper control point of a trajectory. Then the interpolation using splines is conducted to reconstruct the trajectory with smoothed form. The dynamic score based selection method is also exploited to effectively select small and dense control points of the trajectory. In an experimental evaluation our method took the same time and generated a similar amount of errors as the usual approach, but reduced the number of control points needed by over 90%. The reduced number of control points can properly reconstruct a movement path and drastically decrease the number of control point selections required for movement path modification. For control manipulation, the task completion time was reduced and there was less hand movement needed than with conventional method. Our method can be applicable to drawing or curve editing method in immersive In-Situ AR based education, game, design, animation, simulation application domains.

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Systematic Review of the Effect of Glucosamine on Joint Health while Focused on the Evaluation of Claims for Health Functional Food (건강기능식품의 기능성을 중심으로 한 글루코사민의 관절건강 기능성에 대한 체계적 고찰)

  • Kim, Joohee;Kim, Ji Yeon;Kwak, Jin Sook;Paek, Ju Eun;Jeong, Sewon;Kwon, Oran
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.2
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    • pp.293-299
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    • 2014
  • Although the functional ingredient has been evaluated based on scientific evidence by the Ministry of Food and Drug Safety (MFDS), the levels of scientific evidence and consistency of the results might vary according to the emerging data. Therefore, a periodic re-evaluation may be needed in some functional ingredients. In this study, we re-evaluated the scientific evidence for the joint health of glucosamine as a functional ingredient in health functional food. Literature searches were conducted using Pubmed, Cochrane, KISS, and IBIDS databases with the search term of glucosamine in combination with osteoarthritis. The search was limited to human studies published in English, Korean and Japanese. Using the MFDS's evidence based evaluation system for scientific evaluation of health claims, 34 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting the relation between glucosamine and joint health. Among the 34 studies, significant effects for joint health were reported in 28 studies, and their daily intake amount was 1.5 to 2 g. Eleven out of 34 studies were identified, excluding severe radiographic osteoarthritis, and ten from those eleven studies reported significant effects for joint health. Based on this systematic review, we concluded that there was possible evidence to support a relation between glucosamine intake and joint health.

An Intelligent Image Retrieval System using XML (XML을 이용한 지능형 이미지 검색 시스템)

  • 홍성용;나연묵
    • Journal of Korea Multimedia Society
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    • v.7 no.1
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    • pp.132-144
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    • 2004
  • With the rapid development of internet technology, the number of internet users and the amount of multimedia information on the internet is ever increasing. Recently, the web sites, such as e-business sites and shopping mall sites, deal with lots of image information. As a result, it is required to support content- based image retrieval efficiently on such image data. This paper proposes an intelligent image retrieval system, which adopts XML, technology. To support object-based col)tent retrieval on product catalog images containing multiple objects, we describe a multi -level metadata structure which represents the local features, global features, and semantics of image data. To enable semantic-based and content-based retrieval on such image data, we design a XML-Schema for the proposed metadata and show how to represent such metadata using XML- documents. We also describe how to automatically transform the retrieval results into the forms suitable for the various user environments, such as web browser or mobile browser, using XSLT The proposed scheme can be easily implemented on any commercial platforms supporting XML technology. It can be utilized to enable efficient image metadata sharing between systems, and it will contribute in improving the retrieval correctness and the user's satisfaction on content-based e-catalog image retrieval.

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COBie Document Prototype for supporting BIM based Smart Maintenance of Buildings (BIM 기반 건축물 스마트 유지관리 지원 COBie 문서 프로토타입)

  • Koo, Kyo-Jin;Park, Sang-Hun;Cho, Dong-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.60-68
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    • 2019
  • For effective building maintenance, the collection and management of various maintenance date such as work history information and material information is required. Despite the introduction of information management technologies and systems to reduce the amount of maintenance work of buildings, which have become larger and more complex, the maintenance information is not being utilized properly. As an alternative, research on the introduction and utilization of BIM is being conducted continuously. However, the BIM models generated at the design phase are not utilized in practice due to a lack of architectural maintenance information. This study proposed a COBie document prototype to support BIM-based smart maintenance tasks performed by building managers. In order to formalize various types of maintenance work procedures, a BIM-based maintenance process model is presented in two categories: inspection and maintenance. Among the BIM attribute data of the BIM model generated at the design phase, the parameters corresponding to the maintenance necessary information for each basic process are derived. Based on this, we proposed a COBie document prototype consisting of seven spreadsheets. The results of a case study confirmed that the KBIMS library-based BIM model created at the design phase without the maintenance information can be used at the maintenance phase.

Boosting up the Mount Latency of NAND Flash File System using Byte-addressable NVRAM (바이트 접근성을 가지는 비휘발성 메모리 소자를 이용한 낸드 플래시 파일 시스템의 부팅시간 개선 기법)

  • Jeon, Byeong-Gil;Kim, Eun-Ki;Shin, Hyung-Jong;Han, Seok-Hee;Won, Yoo-Jip
    • Journal of KIISE:Computing Practices and Letters
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    • v.14 no.3
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    • pp.256-260
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    • 2008
  • This paper describes an improvement of mount-time delay in NAND Flash file systems. To improve file system mount performance, this work configures a hierarchical storage system with byte-addressable NVRAM and NAND Flash memory, and let the meta data of a file system allocated in the NVRAM. Since the meta data are stored in NVRAM supporting data integrity some of the items, which are stored in Spare area and Object Header area of NAND Flash memory to control meta data of NAND Flash file system, could be eliminated. And also, this work eliminates the scanning operation of the Object Header area of previous work FRASH1.0. The scanning operation is definitely required to find out the empty Object Header address for storing the Object Header data and provokes a certain amount of performance loss in file generation and deletion. In this work, an implemented file system, so-called FRASH1.5, is demonstrated, featuring new data structures and new algorithms. The mount time of FRASH1.5 becomes twice as fast as that of the FRASH1.0. The performance in file generation gets improved by about $3{\sim}8%$. In particular, for most large-size files, the FRASH1.5 has 8 times faster mount time than YAFFS, without any performance loss as seen in the file generation.

The Financial Stability of Before-and-after Retirement -Expectation and Support for the Quality of the Elderly Life- (은퇴 전후 세대 재정안정성 -노년기 삶의 수준에 대한 기대와 지원-)

  • Kim, Eunyoung
    • Korean Journal of Social Welfare
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    • v.66 no.1
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    • pp.61-85
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    • 2014
  • Lately, as the problem of the aged poverty becomes a big social issue, this paper studies the problem of financial stability with respect to the income and consumption of before-and-after retirement generations. After dividing the data in Korean Longitudinal Study of Ageing(KLoSA) into retired and non-retired groups, this study compares the difference among ageing groups by cross analysis and t-test. First, the result tells that the total personal income of retired group is lower than the one of non-retired group. Second, the public pension income benefit ratio of retired group is only 30% of it's total income, and the amount of public pension appears to be 40% of the total pension income. The benefit ratio of the personal pension income is low as about 1% in both groups, The private transfer income of the retired group takes relatively large portion in its total personal income. Third, as people gets older, financial stability gets worse because consumption does not decrease as much as the income decreases. Fourth, it is turned out that the expectation of old life supporting from nation is low in both groups. Fifth, the factors that affects the income of the public pension in the retired group are gender, age, education, and health status, when compared with the factors to the personal total income of the non-retired group. In terms of policy, this paper emphasizes the needs of the intensification of the public pension and the support for the revitalization of the personal pension.

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A Study on the Interannual Variation of Seedfall and Seed Viability of Acer pictum subsp. mono in Natural Broadleaved Forests at Mt. Jungwang (중왕산 천연활엽수림에서 고로쇠나무 낙하종자량 및 종자활력의 연년변이 연구)

  • Kim, Hoi Jin;Kim, Gab Tae
    • Korean Journal of Environment and Ecology
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    • v.29 no.4
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    • pp.503-507
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    • 2015
  • To examine the interannual variation of seedfall and seed viability rates of Acer pictum subsp. mono (APSM), we investigated the annual seedfall and seed viability of APSM in the natural broadleaved forest in Mt. Jungwang, Gangwon-do, from 2009 to 2014. The amounts of annual seedfalls from 2009 to 2014 were revealed to be 5,700, 4,060, 60,900, 403,450 and 310 ea/ha respectively. 2013 is presumed to be the masting year since large amounts of seedfall were revealed, compared to that of the other years in the study period. Also, the amount of seeds was significantly different among seed viabilities. Most fallen seeds were damaged or decayed, accounting for 47.88% of the total, followed by empty seeds, undeveloped seeds and sound seeds in that order. The percentage of sound seeds ranged from 6.7 to 31.0%, which marks the lowest average with 16.74%. In the masting year, 2013, a significantly larger number of sound seeds fell at 125,070 ea/ha, on the forest floor than in the other years (320~17,840 ea/ha). Meanwhile, the ratio of damaged or decayed seeds was the lowest at 38%, although the number of those seeds was the largest, 153,310 ea/ha, for the same year. These results imply that the surplus seeds are supplied for natural regeneration in the masting year, supporting the seed predator satiation hypothesis. More long-term researches should be conducted on the seed production of broadleaved trees.

Water Balance Analysis of Pumped-Storage Reservoir during Non-Irrigation Period for Recurrent Irrigation Water Management (순환형 농업용수관리를 위한 농업용 저수지의 비관개기 양수저류 추정)

  • Bang, Na-Kyoung;Nam, Won-Ho;Shin, Ji-Hyeon;Kim, Han-Joong;Kang, Ku;Baek, Seung-Chool;Lee, Kwang-Ya
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.4
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    • pp.1-12
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    • 2020
  • The extreme 2017 spring drought affected a large portion of South Korea in the Southern Gyeonggi-do and Chungcheongnam-do districts. This drought event was one of the climatologically driest spring seasons over the 1961-2016 period of record. It was characterized by exceptionally low reservoir water levels, with the average water level being 36% lower over most of western South Korea. In this study, we consider drought response methods to alleviate the shortage of agricultural water in times of drought. It could be to store water from a stream into a reservoir. There is a cyclical method for reusing water supplied from a reservoir into streams through drainage. We intended to present a decision-making plan for water supply based on the calculation of the quantity of water supply and leakage. We compared the rainfall-runoff equation with the TANK model, which is a long-term run-off model. Estimations of reservoir inflow during non-irrigation seasons applied to the Madun, Daesa, and Pungjeon reservoirs. We applied the run-off flow to the last 30 years of rainfall data to estimate reservoir storage. We calculated the available water in the river during the non-irrigation season. The daily average inflow from 2003 to 2018 was calculated from October to April. Simulation results show that an average of 67,000 tons of water is obtained during the non-irrigation season. The report shows that about 53,000 tons of water are available except during the winter season from December to February. The Madun Reservoir began in early October with a 10 percent storage rate. In the starting ratio, a simulated rate of 4 K, 6 K, and 8 K tons is predicted to be 44%, 50%, and 60%. We can estimate the amount of water needed and the timing of water pump operations during the non-irrigation season that focuses on fresh water reservoirs and improve decision making for efficient water supplies.