• Korean Journal of Digital Imaging in Medicine
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• v.9 no.2
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• pp.17-21
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• 2007

The purpose to recognize change of average pixel value of acquisition image by control panel's density and right set up method of speed (sensitivity) and exposure dose(mAs) change that dose in purpose digital flatpanel-detector. X -ray generator DHF-158H2(Hitachi, Japan). Detector CXDI 4OG(Canon, Japan), 12 : 1 grid and exposure ray 135 kVp, 250 mA, 10 ms. focus-detector distance 180 cm and used AEC mode. DICOM reflex analysis program used image J that is digital reflex analysis program that offer in United States America National Health Center(National Institutes of Health : NlH) phantom used chest phantom(Anthromorphic : Flukebrome.medicaI USA). An experiment chest phantom that consist by formation equivalence material use because density value( -3${\sim}$+3) in X-ray control panel and seep that is speed step(slow, medium, fast) each control experimentalize. image analysis reflex neted through an experiment using image j each image compare. These was change in dose according to slow, medium, fast and density's change in an experiment result. According to detector sensitivity and density condition set, dose was relationship dissimilarity 500% from 200%. The dose came highest when is density +3 to slow. and dose more increases gray scale's extent could know that rise. Could know whether how equipment set is important through this experiment. cause of disease which change by digital radiography system forward is thought to increase more, it is considered that suitable education by this and continuous interest about equipment need absolutely.

• Biomolecules & Therapeutics
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• v.19 no.2
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• pp.206-210
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• 2011

Natural Killer (NK) cells are the lymphocytes that are derived from hematopoietic stem cells, developed in the bone marrow from hematopoietic stem cells (HSC) by sequential acquisition of functional surface receptors, and express the repertoire of inhibitory and activating receptors. Recently, Osteopontin (OPN) has been identified as a critical factor for differentiation of natural killer cells. However, the detailed mechanism of OPN-induced NK differentiation has been still to be elucidated. Here, we determined the signaling pathway and possible receptor for OPN in NK differentiation. OPN induced expression of Bcl-2 and activation of Erk kinase. Inhibition of Erk pathway decreased the effect of OPN on NK differentiation. In addition, the expression of integrin ${\alpha}9$ was significantly increased by OPN during NK differentiation, suggesting the possible role of a major signaling molecule for OPN- induced NK differentiation.

• Journal of Digital Convergence
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• v.14 no.1
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• pp.407-412
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• 2016

The design in this study containing a consideration of children's free fantasy and experiential acquisition, is convergence in terms of its external use of Solar thermal energy and human friendly software, and is about public design based on eco-friendly playing equipments. Despite several flaws, the modularized solar-light power generation equipment is suitable for realizing the concept of the relationship between the Sun and the life thanks to its being versatile. Playing is equivalent to the world for children in itself, therefore; it should be something flexible to stimulate their fantasy and I imagined the sun, which should be something more than a mere source of power generation, and the children interact with each other by the medium of this equipment.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.6
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• pp.463-472
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• 2020

Direct reprogramming, also known as a trans-differentiation, is a technique to allow mature cells to be converted into other types of cells without inducing a pluripotent stage. It has been suggested as a major strategy to acquire the desired type of cells in cell-based therapies to repair damaged tissues. Studies related to switching the fate of cells through epigenetic modification have been progressing and they can bypass safety issues raised by the virus-based transfection methods. In this study, a protocol was established to directly convert fully differentiated fibroblasts into diverse mesenchymal-lineage cells, such as osteoblasts, adipocytes, chondrocytes, and ectodermal cells, including neurons, by means of DNA demethylation, immediately followed by culturing in various differentiating media. First, 24 h exposure of 5-azacytidine (5-aza-CN), a well-characterized DNA methyl transferase inhibitor, to NIH-3T3 murine fibroblast cells induced the expression of stem-cell markers, that is, increasing cell plasticity. Next, 5-aza-CN treated fibroblasts were cultured in osteogenic, adipogenic, chondrogenic, and neurogenic media with or without bone morphogenetic protein 2 for a designated period. Differentiation of each desired type of cell was verified by quantitative reverse transcriptase-polymerase chain reaction/western blot assays for appropriate marker expression and by various staining methods, such as alkaline phosphatase/alizarin red S/oil red O/alcian blue. These proposed procedures allowed easier acquisition of the desired cells without any transgenic modification, using direct reprogramming technology, and thus may help make it more available in the clinical fields of regenerative medicine.

• Journal of Aerospace System Engineering
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• v.18 no.3
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• pp.27-33
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• 2024

According to the success of the Nuri Space Launch Vehicle (KSLV-II) and the development goal of the next generation space launch vehicle (KSLV-III), it is expected that the domestic geostationary satellite capability will be increased from (1 to 3.7) ton. Also, it is predicted that substantial ability of about 1 ton can be provided for the space exploration of the Moon, Mars, asteroids, etc. The Goheung space launch site is optimized for sun-synchronous small satellites, and due to the essential precondition that the launch trajectory does not impinge another country's sovereign airspace, it is not satisfactory as a geostationary satellite launching site. Its latitude also requires more energy to shape the rotating orbital plane from the initial injection status. This results in a decreasing factor of economic feasibility, including the operating complexity. Therefore, in parallel with the development of a next generation space launch vehicle, the practical process for acquisition of oversea land or sea space launch site near the Earth's equator and research for the optimization of orbiting methods of geostationary satellite injection must be continued.

• Journal of the Korean Society of Radiology
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• v.2 no.3
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• pp.5-9
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• 2008

In the computerized tomography(CT), various filters are using in the reconstruction algorithm to reduce or eliminate the artifacts which are intrinsically induced by the imperfection of mathematical methods for reconstruction, lack of real informations about anatomic structures in the projection image, errors in data acquisition and so on. Hann filter was used to evaluate the filter effects on the elimination of reconstruction artifact in the CT image. The quantitative study was done by changing cut-off frequency of Hann filter from 0.1 to 0.9 with frequency increasement by 0.2. NPS analysis was fulfilled for the quantitative evaluation of filter effect.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.1
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• pp.65-74
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• 2008

Objectives : This experimental study was designed to investigate the effects of Lumbricus extract (LE) on the changes in regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats, and further to determine the mechanism of action of LE. Methods : The changes of rCBF were observed by Laser-Doppler flowmetry (LDF) and the changes of MABP were recorded by a data acquisition system assembled with MacLab and Macintosh. Results : LE significantly increased rCBF in a high dosage(10.0 mg/kg, i.p), but MABP was somewhat increased as compared with baseline. This result suggests that LE significantly increased rCBF by dilating pial arterial diameter. Increase of LE-induced rCBF was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p), an inhibitor of cyclooxygenase, but was not significantly inhibited by pretreatment with methylene blue ($10{\mu}g/kg$, i.p), an inhibitor of guanylate cyclase. Conclusions : LE increased rCBF by dilating pial arterial diameter, and the action of this response was mediated by cyclooxygenase.

• The Journal of Korean Institute for Practical Engineering Education
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• v.1 no.1
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• pp.30-37
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• 2009

The purpose of this study is the development and application of practical education program for the security of semiconductor equipments maintenance technology. For securing the semiconductor equipments maintenance technology, this study aims to research on the Training and Development. The main field of HRD is about the Training and Development. We develop the practical education program applying the ADDIE Model to conduct the education training. This developed program tests the education training on the officers of Samsung Electronics, the maker of semiconductor. By the test, we hope to provide the technology education program focusing on the practical experiences of systematic and effective companies.

• Transactions on Electrical and Electronic Materials
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• v.16 no.6
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• pp.323-327
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• 2015

In this paper, parameters related with partial discharge (PD) were analyzed in SF₆ gas under AC and DC voltages. Three electrode systems (protrusion on conductor, protrusion on enclosure, and free particle) were fabricated to simulate PD defects in a gas-insulated switchgear (GIS). All electrode systems were filled with SF₆ gas at 0.5 MPa. PD pulses were detected using an oscilloscope and a data acquisition (DAQ) based on IEC 60270. To analyze the PD characteristics under AC and DC voltages, parameters such as discharge inception voltage (DIV), discharge extinction voltage (DEV), pulse magnitude, repetition rate, and T-F map were compared. From the experimental results, PD was revealed to have different characteristics under AC and DC, and these results may be useful for diagnosis of power facilities operated under HVDC.

• Speech Sciences
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• v.12 no.3
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• pp.175-183
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• 2005

In this study, realization of strong and weak syllables in English by Korean leaners with low English proficiency was examined through experiment. The aspects of three acoustic characteristics-duration, pitch, amplitude-were measured and compared with native speakers of English. It was assumed that production of duration, pitch and amplitude of strong and weak syllable by Korean learners would be different from that of English native speakers. According to the production experiments, English native speakers produced strong syllable longer, higher and louder than weak syllable. However, Korean leaners produced strong syllable higher and louder than weak syllable, but not longer enough. Specifically, weak syllable by Korean leaners was longer and strong syllable shorter than native speakers. Furthermore, the difference in duration of syllables between Korean leaners and English native speakers is more significant than pitch and amplitude. As a result, the duration was more important cue for the realization of stress than pitch and amplitude. However, Korean leaners did not produce duration of stressed syllables as English native speakers did, even though they produce the pitch and amplitude of stressed syllable in a similar way to native speakers. The reasons for those were considered, too.