• Genomics & Informatics
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• v.14 no.4
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• pp.196-204
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• 2016

Many researchers have found that one of the most important characteristics of the structure of linkage disequilibrium is that the human genome can be divided into non-overlapping block partitions in which only a small number of haplotypes are observed. The location and distribution of haplotype blocks can be seen as a population property influenced by population genetic events such as selection, mutation, recombination and population structure. In this study, we investigate the effects of the density of markers relative to the full set of all polymorphisms in the region on the results of haplotype partitioning for five popular haplotype block partition methods: three methods in Haploview (confidence interval, four gamete test, and solid spine), MIG++ implemented in PLINK 1.9 and S-MIG++. We used several experimental datasets obtained by sampling subsets of single nucleotide polymorphism (SNP) markers of chromosome 22 region in the 1000 Genomes Project data and also the HapMap phase 3 data to compare the results of haplotype block partitions by five methods. With decreasing sampling ratio down to 20% of the original SNP markers, the total number of haplotype blocks decreases and the length of haplotype blocks increases for all algorithms. When we examined the marker-independence of the haplotype block locations constructed from the datasets of different density, the results using below 50% of the entire SNP markers were very different from the results using the entire SNP markers. We conclude that the haplotype block construction results should be used and interpreted carefully depending on the selection of markers and the purpose of the study.

• Journal of the Korean Chemical Society
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• v.34 no.2
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• pp.203-210
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• 1990

As a possible biocompatible and biodegrable polymer skeleton for drug delivery system, block copolymers of L-lactic acid and L-glutamic acid with different composition were synthesized and characterized. Poly (L-lactide) was prepared by polymerization of L-lactide with zine oxide at $130^{\circ}C$ for 72 hrs. 3-Amino-l-propanol was introduced to poly (L-lactide) by an ester linkage in order to initiate polymerization. Polymerization of $\gamma-benzyl-L-glutamate-N-carboxyanhydride(\gamma-BLG-NCA)$ utiliizing the amino group of modified poly (L-lactide) as an initiator gave rise to the block copoly $(L-lactide-\gamma-benzyl-L-glutamate).$ The NMR study of resulting block copolymers showed that the composition of L-lactic acid and $\gamma-benzyl-L-glutamate$ in block copolymers was depended on the weight ratio of poly (L-lactide) and $\gamma-BLG-NCA.$ The thermal properties of the resulting block copolymers were determined by the differential scanning calorimetry and by the thermogravimetry.

• Journal of the Korean Solar Energy Society
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• v.29 no.6
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• pp.81-87
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• 2009

The purpose of this study is to evaluate of the outdoor thermal environment by building scale and block type as variable factors. In this study, 18 cases of office in central business district that have different condition are compared about their surface temperature, HIP(Heat Island Potential), and MRT(Mean Radiant Temperature). They are simulated with 3-dimension numerical simulation software named Hoyano-model. The output results contain visualized distribution chart and numerical data. The results of evaluation are as follows. (1)The surface temperature of the building becomes higher as building coverage ratio is higher but floor area ratio is lower. In same conditions, unified block type is maximum $3.2^{\circ}C$ higher than divided block type. (2)HIP shows different daily pattern as block type. During daytime, divided block type is much higher than unified block type but after sunset, it is changed. (3)MRT shows different distribution pattern as sunlight moves expecially at noon. (4)As the results of this study, cases that have high floor area ratio condition show lower surface temperature by tendency to stay low indoor temperature in office building and big rate of windows on building surface.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.8A
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• pp.725-732
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• 2002

Block-wise MAP (Maximum A posteriori) decoding algorithm for turbo-codes requires less memory than Log-MAP decoding algorithm. The ER (Bit Error Rate) performance of previous block-wise MAP decoding algorithm depend on the block length and training length. To maximize hardware utilization and perform successive decoding, the block length is set to be equal to the training length in previous MAP decoding algorithms. Simulation result on the BER performance shows that the EBR performance can be maintained with shorter blocks when training length is sufficient. This paper proposes an architecture for area efficient block-wise MAP decoder. The proposed architecture employs the decoding schema for reducing memory by using the training length, which in N times larger than block length. To efficiently handle the proposed schema, a pipelined architecture is proposed. Simulation results show that memory usage can be reduced by 30%~45% in the proposed architecture without degrading the BER performance.

• Journal of the Korean Society of Tobacco Science
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• v.23 no.2
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• pp.95-102
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• 2001

This study was conducted to obtain the basic information for breeding of burley(N. tabacum cv. burley) and sun-cured tobacco(N. tabacum cv. sun-cured) variety. Two burley(Burley 21, KB 108), and T.I. 1068 and three sun-cured varieties(Yeonbyeon 3, Jaheungyeon and Jaraehong) were diallel crossed and 15 combinations of F$_1$generations were made in 1998, respectively. Six parental varieties, 15 F$_1$s were grown under the complete randomized block design with 3 replications at Chonju Experiment Station, Korea Ginseng & Tobacco Research Institute in 2000. The data of 12 quantitative characters were measured for degree of heterosis. The results obtained are as follows. Heterosis of F$_1$generation was positive in weight per leaf, plant height, stem diameter, yield, leaf length and total alkaloid content. Cross combinations between either Burley 21 or KB 108 and sun-cured varieties showed comparatively high heterosis in each characters.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.9
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• pp.4603-4624
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• 2016

In this paper, a new reversible watermarking algorithm with adaptive embedding threshold matrix is proposed. Firstly, to avoid the overflow and underflow, two flexible thresholds, TL and TR, are applied to preprocess the image histogram with least histogram shift cost. Secondly, for achieving an optimal or near optimal tradeoff between the embedding capacity and imperceptibility, the embedding threshold matrix, composed of the embedding thresholds of all blocks, is determined adaptively by the combination between the composite chaos and the average energy of Integer Wavelet Transform (IWT) block. As a non-liner system with good randomness, the composite chaos is suitable to search the optimal embedding thresholds. Meanwhile, the average energy of IWT block is calculated to adjust the block embedding capacity, and more data are embedded into those IWT blocks with larger average energy. The experimental results demonstrate that compared with the state-of-the-art reversible watermarking schemes, the proposed scheme has better performance for the tradeoff between the embedding capacity and imperceptibility.

• The Korean Journal of Pain
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• v.4 no.2
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• pp.186-190
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• 1991

Causalgia is an extremely incapacitating disease often associated with a major peripheral nerve injury, which is characterized by sustained diffuse burning pain, allodynia and hyperpathia. The condition follows traumatic nerve lesions, often combined with vasomotor and sudomotor disturbances and later trophic changes. While sympathectomy has been the classical treatment of causalgia, others nonsurgical therapies such as regional sympathetic block, IV regional sympathetic block, oral adrenolytic drugs, transcutaneous electrical nerve simulation, physical theraphy, cryotheraphy and psychotheraphy have been used. Causalgia is rare in children and early treatment is controversial because of the possibility of many different complications following aggressive treatment. This is a report of a 6-year-old girl with causalgia suffered after a right posterior tibial nerve injury following an intragluteal injection of an antipyretics. We successfully treated this syndrome with continuous epidural block using 0.5% lidocaine and no specific complication was encountered.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.5 no.1
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• pp.13-19
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• 2012

In this paper, we propose the pulmonary nodule detection method based on hierarchical 3D block analysis. The proposed system consists of two main part. In the first part, we select the block which is need to analysis. In the second part, we analysis the selected blocks. We extract the shape based features of the object in the selected blocks. Support Vector Machine is applied to the extracted features to classify into nodules and non-nodules.

• The Korean Journal of Pain
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• v.18 no.2
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• pp.279-283
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• 2005

Biplane fluoroscopy is usually used in angiography. Biplane fluoroscopy gives a biplane image with high resolution during the performance of operations. Trigeminal nerve blocks are effective treatment modalities for trigeminal neuralgia, and maxillary nerve block is the most dangerous procedure among them. The anatomic structures can change after head and neck surgery, so the trigeminal nerve block procedures cannot be done so easily. We used biplane fluoroscopy in these difficult cases. Our first case was a 60-year-old man who had undergone maxillary nerve block. The second case was of a 64-year-old man who had pulsed radiofrequency lesioning of mandibular nerve performed after head and neck surgery. With biplane fluoroscopy, we got good results without any complications.

• Korean Journal of Computational Design and Engineering
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• v.21 no.2
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• pp.177-185
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• 2016

In this paper, an optimal planning system for operating transporters in shipyard is developed. The system is designed to utilize the geometries of shipyard, and manage the data of blocks and transporters directly. There are four major menus such as shipyard map management based on GIS, block transportation request, transporter management, and optimal transportation planning in the system. The geometries and properties of the shops, roads, and addresses are manipulated in the shipyard map management menu. The block transportation requests and the properties of transporters are managed in the block transportation request and transporter management menus, respectively. The optimum transportation is planned automatically for minimizing the unload times of the transporters, and the optimum transportation plans are confirmed and printed to the transporter drivers. The effectiveness of the system was verified through the application to a large-sized shipyard.