• Journal of Microbiology
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• v.41 no.2
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• pp.63-72
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• 2003

Chronic inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis, affects around 2 in every 1000 individuals in western countries and its incidence, particularly amongst children, is increasing. IBD shows extreme morbidity with impact on all aspects of quality of life. If left untreated, IBD can lead to death. Conventional treatment of IBD involves powerful immunosuppressive chemotherapies and surgical intervention. Long-term anti-inflammatory medication is required and so patients are often subject to a spectrum of unpleasant side effects. Interleukin-10 (IL-10) is a cytokine that acts to suppress inflammation. When however administered by injection, the high levels of IL-10 that are distributed throughout the body also lead to side effects. Lactococcus lactis can be genetically engineered to secrete biologically active cytokines. When applied to the mucosa, these L. lactis can actively deliver such cytokines. By use of this principle we developed a new therapeutic approach for IBD. Administration of L. lactis that secretes murine IL-10 cures and prevents IBD in mice. The use of the engineered L. lactis gets around the problem of delivering IL-10, allowing dramatic reduction of the effective dose. A sincere concern exists about the possible dangers of uncontrolled, deliberate release of genetically modified microorganisms, such as could occur following application in healthcare. We engaged in the establishment of adequate means for biological growth control of engineered L. lactis by targeted gene exchange between thyA and hIL-10.

• Journal of the Korean Society for Library and Information Science
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• v.14
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• pp.93-130
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• 1987

Scientific communication is an information exchange activity between scientists. Scientific communication is carried out in a variety of informal and formal ways. Basically, informal communication takes place by word of mouth, whereas formal communication occurs via the written word. Science is a highly interdependent activity in which each scientist builds upon the work of colleagues past and present. Consequently, science depends heavily on scientific communication. In this study, three mathematical models, namly Brillouin measure, logistic equation, and Markov chain are examined. These models provide one with a means of describing and predicting the behavior of scientific communication process. These mathematical models can be applied to construct quality filtering algorithms for subject literature which identify synthesized elements (authors, papers, and journals). Each suggests a different type of application. Quality filtering for authors can be useful to funding agencies in terms of identifying individuals doing the best work in a given area or subarea. Quality filtering with respect to papers can be useful in constructing information retrieval and dissemination systems for the community of scientists interested m the field. The quality filtering of journals can be a basis for the establishment of small quality libraries based on local interests in a variety of situations, ranging from the collection of an individual scientist or physician to research centers to developing countries. The objective of this study is to establish the theoretical framework for informetrics which is defined as the quantitative analysis of scientific communication, by investigating mathematical models of scientific communication.

• Imaging Science in Dentistry
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• v.50 no.3
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• pp.183-192
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• 2020

Purpose: This study was performed to assess the accuracy of preoperative cone-beam computed tomography (CBCT), when justified for other reasons, in locating the apical foramen and establishing the working length. Materials and Methods: Six electronic databases were searched for studies on this subject. All studies, of any type, were included if they compared measurements of working length with preoperative CBCT to measurements using an electronic apex locator (EAL) or histological reference standard. Due to the high levels of heterogeneity, an inverse-variance random-effects model was chosen, and weighted mean differences were obtained with 95% confidence intervals and P values. Results: Nine studies were included. Compared to a histological reference standard, CBCT indicated that the apical foramen was on average 0.40 mm coronal of its histological position, with a mean absolute difference of 0.48 mm. Comparisons were also performed to an EAL reference standard, but the conclusions could not be considered robust due to high levels of heterogeneity in the results. Conclusion: A low level of evidence is produced suggesting that preoperative CBCT shows the apical foramen to be on average 0.40 mm coronal to its histological position, with a mean absolute difference of 0.48 mm.

• Journal of Digital Convergence
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• v.9 no.1
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• pp.107-114
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• 2011

In order to have the highest level of a certain society's technology be evaluated as digital contents technology the value concept of such technology's social utilization must be established while active investment on the technology takes place and makes it the subject of social capitalization. This study wishes to discuss the strategies and methods of establishing and managing IP holding company which requires business activation with digital contents technology at its base, research ways of vitalizing IP holding company to expand social utility values of contents technology, suggest necessary systemic improvements and investment activation methods, management structure, and governance structure by investigating ways to stimulate the industrialization of contents technology through the establishment and management of this IP holding company, and finally come up with a realistic measure to establish and manage a IP holding company. Strategies on commercialization of digital contents technology and acceleration of technology development, as well as activation of venture business set-ups will be analyzed and suggested based on such suggestions while IP holding company's digital contents technology investment activation model will be established to produce means to realize discovering superior contents companies and activation of investment, and activating high quality contents production for the global market.

• Acta Via Serica
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• v.4 no.2
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• pp.61-77
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• 2019

Following the introduction of Buddhism to China by Xuanzang (玄奘 602-664), the visual tradition of an itinerant monk became a popular subject. This theme developed into a Buddhist figure with an accompanying tiger, especially in Korea where tigers were an object of worship and ritual. This paper examines Korean examples of post-itinerant monk Buddhist figures accompanied by tigers, in particular the portrayal of itinerant monks as arhats and sansins. The supernatural powers of arhats were diverse, and they often tamed the tigers who then accompanied them on their journeys. The arhat, who was introduced during the Unified Silla period and gained popularity during the Goryeo period, was loved by the general public during the Joseon Dynasty as a familiar presence that brought good fortune. Special portraits of monks accompanied by a tiger, known as sansindo (山神圖), form a unique Korean genre. Sansin religious beliefs formed through a fusion of the newly introduced Buddhism and the age-old indigenous worship of sacred mountains and tigers. Most Buddhist temples include a sansin shrine containing on altar with sansin statues and portraits. Tigers in the portraits of itinerant monks and the stories of Buddhist monks who tamed tigers became famous and widely accepted in Korea, a nation already rich in tiger lore. Folklore and indigenous shamanism contributed to the establishment of Buddhism in Korea, and tigers played a central role in this.

• Journal of the Korea Society of Computer and Information
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• v.21 no.2
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• pp.43-49
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• 2016

In this paper, we propose the controllability function and service design to efficiently implement the control of the disaster communication network, using Internet of Things(IoT) Technology. In accordance with the spread of Information Communication Technology(ICT), the era for building a disaster communications system without exclusion over the entire areas has emerged. National wireless mesh networks for public safety and disaster relief have been evolving to strengthen the pre-disaster response system using the latest technologies through the convergence of various technologies and services from the viewpoint of the command and control between disaster response agencies. In line with such a technological paradigm shift, the controllability of the objects in the IoT has been emerging as a key quality requirement of a disaster communications system. In this study, the objects are classified by the subject of control according to the IoT component, such as data, network resources and services in order to effectively implement their controllability. In addition, based on the destination of this controllability, technologies and services have been designed that can reduce the damage caused by disasters. Technologies and services that were derived from this study must be implemented in the current disaster safety network systems together with the establishment of an infrastructure for the networks in order that all persons are able to effectively utilize the disaster communications system for their safety.

• Hwankyungkyoyuk
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• v.21 no.1
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• pp.57-69
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• 2008

The purpose of Environmental subject in the Korean school is pretty much similar to that of international organization. Because it doesn't apply the characteristics of School Education to environmental education, this school environmental education purpose needs to be discussed. The purpose of this study is to establish the reasonable purpose of school environmental education by analyzing the educational views. This study have been done through review of research literature, which usually includes references and papers on environmental education, school environmental education, educational point of view, educational purpose. It analyzed three kinds of views on education: technological view on education, initiation view on education, socialization view on education. The results are as follows: The purpose of school environmental education from technological view on education is environmental education activity itself that educates students to put the environmental preservation value into action. Initiation view on education aims at school environmental education as activities that instruct students on intellectual ability in order to develop a comprehensive view of intelligence. The purpose of environmental education in school on the basis of socialization view on education focuses on activities that authoritative teachers transmit the social value of environmental preservation to students in school.

• Asian Journal of Business Environment
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• v.3 no.2
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• pp.5-15
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• 2013

Purpose - This pilot study explores the gap between venture capitalists and young business graduates in Pakistan. Though the young graduates remain enthusiastic about choosing entrepreneurship as a profession, their success is subject to financial constraints. Research design, data, methodology - We administered a Likert-scale based questionnaire to 200 business graduates from June to July 2012, and interviewed ten venture capitalists from Islamabad and Lahore-two highly business oriented cities of Pakistan-to collect the data. The survey participation was on a voluntary basis without any financial sponsorship. Findings- There is a communication gap between the two parties (venture capitalists and business graduates), and a lack of trust in the entrepreneurial education and training offered in the educational institutions in Pakistan. The study, however, reveals the leading role of the Government in reducing this gap through certain measures. Conclusions - Some measures that can reduce the gap between venture capitalists and young graduates are: association of business schools with industry; financial institutions'initiatives to financially support the small and medium level projects of the economics and business students during their studies; establishment of placement bureaus in the business schools; and organization of regular open houses in the universities.

• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.4
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• pp.765-774
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• 1998

This purpose of this study was to contribute to the establishment of nutriton labeling and consumer education about food label by offereing basic information. Survey was carried out by questionnaire method. Subject groups were middle and high school female teachers and they were asked questions about their utilization and satisfaction of the current food labeling system, their awareness of the nutrition labeling and its necessity, and their acceptance of the future enforcement of nutrition labeling system. Questionnaires were distributed to 500 middle school female teachers in Chungbuk and Kyoggi area. Out of 340 reports(68%) collected, 311 reports(91.5%) were analyzed using SAS computer program. Most of the respondents payed much attention to the labels of the food at the time of purchase, the degree of their satisfaction in the current food labeling system was low. Concerning the awareness on nutrition labeling, Home Economics teachers knew better than non-Home Economics whether there were the regulations of nutrition labeling in Korea or not. Ninety-six percent of respondents answered that nutrition labeling is necessary. Home Economics teachers recognized the necessity of nutrition labeling more strongly than non-Home Economics teachers. Sixty eight percent of the respondents showed positive attitude to the actuation of nutrition labeling.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.4 no.1
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• pp.103-127
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• 1980

Due to the rapid growth of publications, librarians have been facing the problems caused by the shortage of stack as well as the quality deterioration of library collections. This naturally disappointed the user communities and the present library activities are weak and inadequate. It seems to the author that one of the desirable actions in remedying this problems is to weed library collections properly and regulraly. The purpose of this study is to establish weeding criteria in library collections, particulary in the fields of polictical science, economics and law In order to establish weeding criteria, shelf-time period which is the length of time that a book remains on the shelf between the last two users of a volume, was measured by examining the book cards or date-due slips of circulating books and collections which remained in the stack. The results of this study are as follows: (1) In the fields of political science economics and law, the shelf-time periods of general materials in Korean for circulation was measured. (2) This study shows shelf-time periods that vary in different subject fields. (3) Combining the shelf-time periods of books in active circulation and the total collection including books which have never been circulated, the size of library holdings which may satisfy a certain percentage of the current circulation can be estimated.