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Vasorelaxant and hypotensive effects of trazodone in Guinea pig (기니픽에서 trazodone의 혈관 이완 및 혈압 하강 효과)

  • Kim, Shang-Jin;Kang, Hyung-Sub;Kim, Jin-Shang
    • Korean Journal of Veterinary Research
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    • v.45 no.4
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    • pp.485-493
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    • 2005
  • We studied the effects of trazodone on arterial blood pressure in anesthesized guinea pigs, and on vascular responses in isolated thoracic aorta. Trazodone produced a concentration-dependent relaxation in phenylephrine-precontracted endothelium intact (+E) rings, but not in a KCl-precontracted aortic rings. These relaxant effects of trazodone on +E rings were significantly greater than those on denuded (-E) rings. The trazodone-induced relaxation was suppressed by glibenclamide and tetrabutylammonium, but not by N(G)-nitro-L-arginine (L-NNA), N(omega)-nitro-L-arginine methyl ester (L-NAME), methylene blue (MB), nifedipine, indomethacin, 2-nitro-4-carboxyphenyl-n,n-diphenylcarbamate (NCDC) and clotrimazole. In vivo, infusion of trazodone elicited a significant decrease in arterial blood pressure. Trazodone-induced blood pressure lowering was markedly inhibited by intravenous pretreatment of prazosin but not by pretreatment of saponin, L-NNA, L-NAME, MB, nifedipine, glibenclamide, clotrimazole and NCDC. In addition, trazodone produced an increase in twitch force of isolated papillary muscle and left ventricular pressure of perfused heart. These findings suggest that the endothelium-independent vasorelaxant effect of trazodone may be explained by activation of $Ca^{2+}$-activated and ATP-sensitive $K^+$ channels, and the hypotensive effect of trazodone is not associated with cardiac contraction.

Shopping Value of the Consumers Who Purchase Fashion/Beauty Products Using Group Buying Social Commerce and Private Shopping Malls (공동구매형 소셜커머스와 프라이빗 쇼핑몰을 이용하여 패션/뷰티 제품을 구매하는 소비자들의 쇼핑 가치)

  • Seo, Sangwoo;Cho, Yunjin
    • Journal of the Korean Society of Clothing and Textiles
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    • v.38 no.2
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    • pp.161-174
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    • 2014
  • This study performs an investigative research on the shopping value of consumers who purchase fashion/beauty products using group buying social commerce among the types of social commerce and private shopping malls. We provide basic knowledge on consumer behavior using social commerce newly appeared as shopping channels. For the method, the research was performed by designing a sequential integration method of conducting quantitative verification after qualitative research. As a result of qualitative research, multiple shopping values have been shown as the common shopping values of consumers using two types of shopping malls. The dimensions are price, quality, convenience, interaction, information, reliability, hedonic and impulse buying values. A total of eight sub-dimensions have appeared due to performing quantitative verification on the shopping value of group buying social commerce. The dimensions are same as the results from the qualitative research. The shopping value of consumers who purchase fashion/beauty products using private shopping malls has been classified into seven dimensions (except interaction value).

A Study on the Customer Experience Analysis for the Silver Generation in the Communication Service Market using CEM (CEM을 활용한 통신서비스 시장의 실버고객 경험분석에 관한 연구)

  • Bae, Jae-Ho;Wang, Gi-Nam
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.32 no.2
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    • pp.66-75
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    • 2009
  • As the population of the silver generation is increasing, the importance and effects of the market for the silver generation are also growing. We segments the categories of the silver generation into six sub-segments using based on the factors like life style, life stage, or performing role from the point of view in communication industry. After segmenting those categories, we observed the experience of each segmented group in detail. Likewise, we executed both FGD(Focused Group Discussion) and participants' observations together to effectively collect the expressed and/or potential needs. Customer's experience was collected along the touch points and customer corridors after dividing the customer's experience world into two groups; communication styles in usual life (life log) and direct contact channels. The effects of delivering an affirmative customer's experience would be empowered by eliminating negative experiences or complementing affirmative experiences. For this purpose, this paper presents the improvement points for the better customer's experience based on the observed customer's experience. This paper presented a sample way of customer-centric approach to design the services or products in the communication industry. In addition to that, the analyzed results of this paper will be useful to find out an effective approach to the market of silver generation.

Single-silicon TFT Structure for Kink-effect Suppression with Symmetric Dual-gate by Three Split floating N+ Zones (Kink-effect 개선을 위한 세 개의 분리된 N+ 구조를 지닌 대칭형 듀얼 게이트 단결정 TFT 구조에 대한 연구)

  • Lee, Dae-Yeon;Hwang, Sang-Jun;Park, Sang-Won;Sung, Man-Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.5
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    • pp.423-430
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    • 2005
  • In this paper, we have simulated a Symmetric Dual-gate Single-Si TFT which has three split floating $n^{+}$ zones. This structure reduces the kink-effect drastically and improves the on-current. Due to the separated floating $n^{+}$ zones, the transistor channel region is split into four zones with different lengths defined by a floating $n^{+}$ region. This structure allows an effective reduction of the kink-effect depending on the length of two sub-channels. The on-current of the proposed dual-gate structure is 0.9 mA while that of the conventional dual-gate structure is 0.5 mA at a 12 V drain voltage and a 7 V gate voltage. This results show a $80 {\%}$ enhancement in on-current by adding two floating $n^{+}$ zones. Moreover we observed the reduction of electric field In the channel region compared to conventional single-gate TFT and the reduction of the output conductance in the saturation region. In addition we also confirmed the reduction of hole concentration in the channel region so that the kink-effect reduces effectively.

40 Gbps All-Optical 3R Regeneration and Format Conversion with Related InP-Based Semiconductor Devices

  • Jeon, Min-Yong;Leem, Young-Ahn;Kim, Dong-Churl;Sim, Eun-Deok;Kim, Sung-Bock;Ko, Hyun-Sung;Yee, Dae-Su;Park, Kyung-Hyun
    • ETRI Journal
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    • v.29 no.5
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    • pp.633-640
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    • 2007
  • We report an experimental demonstration of 40 Gbps all-optical 3R regeneration with all-optical clock recovery based on InP semiconductor devices. We also obtain alloptical non-return-to-zero to return-to-zero (NRZ-to-RZ) format conversion using the recovered clock signal at 10 Gbps and 40 Gbps. It leads to a good performance using a Mach-Zehnder interferometric wavelength converter and a self-pulsating laser diode (LD). The self-pulsating LD serves a recovered clock, which has an rms timing jitter as low as sub-picosecond. In the case of 3R regeneration of RZ data, we achieve a 1.0 dB power penalty at $10^{-9}$ BER after demultiplexing 40 Gbps to 10 Gbps with an eletroabsorption modulator. The regenerated 3R data shows stable error-free operation with no BER floor for all channels. The combination of these functional devices provides all-optical 3R regeneration with NRZ-to-RZ conversion.

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Condensation Heat Transfer and Pressure Drop of R245fa in a Plate-shell Heat Exchanger (Plate-shell 열교환기에서 R245fa의 응축열전달 및 압력강하 특성에 관한 연구)

  • Kim, Sung Woo;Baek, Changhyun;Song, Kang Sub;Kim, Yongchan
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.28 no.12
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    • pp.495-501
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    • 2016
  • Condensation heat transfer and pressure drop of R245fa were investigated experimentally in a plate-shell heat exchanger which consisted of thirty seven counter flow channels formed by thirty-eight plates with a chevron angle of $50^{\circ}$. The upflow of the water in one channel receives heat from the downflow of R245fa in the other. The effects of refrigerant mass flux, imposed heat flux, refrigerant saturation pressure, and mean vapor quality on the heat transfer characteristics were explored in detail. Experimental correlations were proposed to predict the condensation heat transfer coefficient and friction factor in terms of the Boiling number, Reynolds number, and Prandtl number. In the experiments, the mean vapor quality in the refrigerant channel was varied from .22 to .82, mass flux from 3 to $5kg/m^2$, imposed heat flux from 1 to $3kW/m^2$, and system pressure from .61 to .81 MPa.

A MAC Protocol for Link Maintenance in Multichannel Cognitive Radio Ad Hoc Networks

  • Li, Jingye;Luo, Tao;Gao, Jing;Yue, Guangxin
    • Journal of Communications and Networks
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    • v.17 no.2
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    • pp.172-183
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    • 2015
  • To provide an efficient link maintenance approach, we propose a cross layer medium access control (LM-MAC) protocol for multichannel cognitive radio ad hoc networks. Link establishment and reliable transmission are two key problems for a perfect link maintenance mechanism. Since the cognitive user (CU) pairs have to reestablish their links each frame, in the proposed MAC protocol, three different access modes are designed to guarantee transmission efficiency in continuous frames. To enhance the transmission reliability, each CU will create a father spectrum list (FSL) after joining in the network. FSL is divided into three groups of sub-channels with different functions to compensate the packet loss caused by the primary users' appearance and the deep fading. Meanwhile, since the transmitter and the receiver will share the same FSL, periodical cooperative sensing is adopted to further optimize the former problem. Finally, compared with the existing opportunistic multichannel (OMC)-MAC protocol, the proposed LM-MAC protocol achieves better system performance in terms of saturation throughput, continuity and access delay.

Error Concealment Based on Multiple Representation for Wireless Transmission of JPEG2000 Image

  • Ou, Yang;Lee, Won-Young;Yang, Tae-Uk;Chee, Sung-Taek;Rhee, Kyung-Hyune
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.1C
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    • pp.68-78
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    • 2008
  • The transmission of multimedia information over error-prone channels such as wireless networks has become an important area of research. In this paper, we propose two Error Concealment(EC) schemes for wireless transmission of JPEG2000 image. The Multiple Representation(MR) is employed as the preprocessing in our schemes, whereas the main error concealing operation is applied in wavelet domain at receiver side. The compressed code-stream of several subsampled versions of original image is transmitted over a single channel with random bit errors. In the decoder side, the correctly reconstructed wavelet coefficients are utilized to recover the corrupted coefficients in other sub-images. The recovery is carried out by proposed basic(MREC-BS) or enhanced(MREC-ES) methods, both of which can be simply implemented. Moreover, there is no iterative processing during error concealing, which results a big time saving. Also, the simulation results confirm the effectiveness and efficiency of our proposed schemes.

Performance Comparison of Channelization Schemes for Flexible Satellite Transponder with Digital Filter Banks (디지털 필터뱅크 기반 플렉서블 위성중계기를 위한 채널화 기법의 성능비교 연구)

  • Lee, Dong-Hun;Kim, Ki-Seon
    • Journal of the Korea Institute of Military Science and Technology
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    • v.13 no.3
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    • pp.405-412
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    • 2010
  • The purpose of this paper is to compare complexity and to assess flexibility of competing transponder architectures for satellite communication services. For performance comparison, we consider three channelization techniques: digital down converter(DDC) based on the use of the cascaded integrator-comb(CIC) filter, tuneable pipeline frequency transform(T-PFT) based on the tree-structure(TS) and variable oversampled complex-modulated filter banks(OCM-FB) based on the polyphase FFT(P-FFT). The comparison begins by presenting a basic architecture of each channelization method and includes analytical expressions of the number of multiplications as a computational complexity perspective. The analytical results show that DDC with CIC filter requires the heavy computational burden and the perfect flexibility. T-PFT based on the TS provides the almost perfect flexibility with the low complexity over DDC with the CIC filter for a large number of sub-channels. OCM-FB based on the P-FFT shows the high flexibility and the best computational complexity performance compared with other approaches.

Development of Processing System of the Direct-broadcast Data from the Atmospheric Infrared Sounder (AIRS) on Aqua Satellite

  • Lee Jeongsoon;Kim Moongyu;Lee Chol;Yang Minsil;Park Jeonghyun;Park Jongseo
    • Korean Journal of Remote Sensing
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    • v.21 no.5
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    • pp.371-382
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    • 2005
  • We present a processing system for the Atmospheric Infrared Sounder (AIRS) sounding suite onboard Aqua satellite. With its unprecedented 2378 channels in IR bands, AIRS aims at achieving the sounding accuracy of radiosonde (1 K in 1-km layer for temperature and $10\%$ in 2-km layer for humidity). The core of the processor is the International MODIS/AIRS Processing Package (IMAPP) that performs the geometric and radiometric correction for generation of Level 1 brightness temperature and Level 2 geophysical parameters retrieval. The processor can produce automatically from received raw data to Level 2 geophysical parameters. As we process the direct-broadcast data almost for the first time among the AIRS direct-broadcast community, a special attention is paid to understand and verify the Level 2 products. This processor includes sub-systems, that is, the near real time validation system which made the comparison results with in-situ measurement data, and standard digital information system which carry out the data format conversion into GRIdded Binary II (GRIB II) standard format to promote active data communication between meteorological societies. This processing system is planned to encourage the application of geophysical parameters observed by AIRS to research the aqua cycle in the Korean peninsula.