• Title/Summary/Keyword: Sub--Channels

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Oxidative stress impairs the meat quality of broiler by damaging mitochondrial function, affecting calcium metabolism and leading to ferroptosis

  • Chen, Zuodong;Xing, Tong;Li, Jiaolong;Zhang, Lin;Jiang, Yun;Gao, Feng
    • Animal Bioscience
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    • v.35 no.10
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    • pp.1616-1627
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    • 2022
  • Objective: This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers. Methods: In this study, a total of 144 one-day-old male Ross 308 chicks were divided into 3 groups (control group, saline group, and hydrogen peroxide [H2O2] group) with 6 replicates of 8 broilers each. The study lasted for 42 d. The broilers in the saline and H2O2 groups were intraperitoneally injected with 0.75% saline and 10.0% H2O2 on the 16th and 37th day of the experimental period respectively, the injection volumes were 1.0 mL/kg of broiler body weight. On the 42nd day of the experimental period, two chicks were randomly selected from each cage, a total of thirty-six chicks were stunned by electric shock and slaughtered to collect breast muscle samples. Results: The H2O2 exposure reduced pH value, increased drip loss and shear force of breast meat (p<0.05), impaired the ultrastructure and function of mitochondria. The H2O2 exposure damaged the antioxidant system in mitochondria, excessive reactive oxygen species carbonylation modified calcium channels on mitochondria, which impaired the activities of key enzymes on calcium channel, resulted in the increased calcium concentration in cytoplasm and mitochondria (p<0.05). In addition, the H2O2 exposure increased the iron content and lipid peroxidation (p<0.05), which induced ferroptosis. Conclusion: Oxidative stress could impair meat quality by causing mitochondrial dysfunction, resulting in calcium metabolism disorder and ferroptosis.

Cooling Performance Analysis of Sub-scale Calorimeter (축소형 칼로리미터의 냉각성능 해석)

  • 조원국;문윤완
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2003.05a
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    • pp.9-12
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    • 2003
  • A cooling performance analysis has been made in the 8-channel calorimeter based on sub-scale KSR-III engine. Three-dimensional heat transfer analysis in cooling channels has been performed using the heat flux distribution through the chamber wall predicted from axi-symmetric compressible flow inside the combustion chamber. The heat flux distribution was verified against the published literature. Presented for the development and operation of the calorimeter are the coolant pressure drop, coolant temperature rise and the maximum chamber wall temperature.

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Specific Resistance (K2´) of Dust Layer Deposited on Porous Media (다공성 필터에서의 여과 분진층 비저항 연구)

  • 이선희;이경미;조영민
    • Journal of Korean Society for Atmospheric Environment
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    • v.20 no.3
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    • pp.371-380
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    • 2004
  • In the dust separation by using porous filter media, the structure of dust layer deposited on the filter surface of filter medium directly affects the effective filtration. The present study has investigated the specific resistance (K$_2$') of the dust layer and its porosity ($\varepsilon$$_{c}$) for three different filters; FA composite filter, metal fiber filter and stainless filter. The specific resistance (K$_2$') increased and at the same time the cake porosity ($\varepsilon$$_{c}$) decreased with the increase of filtration velocity, possibly due to the compressible effect of dust layer. However, under the low dust concentration, subsequent dust particles would block the open channels through the layer resulting in high specific resistance of the layer. The FA composite filter among three filters was shown to be the most effective filter for dust cake filtration at low filtration velocities less than 0.1 m/s for an approximate dust concentration of 5 g/㎥.

Cooling Performance Analysis of a Sub-scale Calorimeter (축소형 칼로리미터의 냉각성능 해석)

  • 조원국;문윤완
    • Journal of the Korean Society of Propulsion Engineers
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    • v.7 no.3
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    • pp.8-14
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    • 2003
  • A cooling performance analysis has been made in the 8-channel calorimeter based on sub-scale KSR-III engine. Three-dimensional heat transfer analysis in cooling channels has been performed using the heat flux distribution through the chamber wall predicted from axi-symmetric compressible flow inside the combustion chamber. The heat flux distribution is verified against the published literature. Presented for the development and operation of the calorimeter are the coolant pressure drop, coolant temperature rise and the maximum chamber wall temperature. Required coolant flow rate is determined for given chamber pressure. Cooling performance is also predicted for temperature dependant coolant properties.

Performance Analysis of Synchronous Downlink MC-CDMA with Precoding and Frequency Offset

  • Jang, Won-Mee;Lee, Moon-Woo
    • Journal of Communications and Networks
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    • v.9 no.2
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    • pp.192-197
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    • 2007
  • We analyze the performance of code division multiple access (CDMA) system with multicarrier (MC) that employs precoding in synchronous downlink channels. Even though considerable efforts are undergoing for frequency offset estimation and correction, it is inevitable for the system to bear the remaining frequency offset. Therefore it is important to predict accurately the system performance in the presence of the residual frequency offset. We obtain the bit error rate (BER) performance in terms of the number of users, the spreading factor, the number of sub-carriers, and frequency offset. We assume that the spreading factor is equal to the number of sub-carriers, although we can generalize the case. The simulation results show that the BER of MC-CDMA with precoding shows a performance that varies with frequency offset as well as system loading.

Study on the Runoff Estimation Considering Stream Order (하천차수를 고려한 유출량 산정에 관한 연구)

  • Choi, Jong-In;Kang, Sang-Hyeok
    • Journal of the Korean Society of Hazard Mitigation
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    • v.5 no.4 s.19
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    • pp.17-27
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    • 2005
  • In this paper the watershed is divided by stream order law of Horton to estimate the runoff with stream order. We use the contour data to extract spatially distributed topographical information like stream channels and networks of sub-basins. A contour model is developed, validated, and adopted to estimate the effective stream order number for the runoff. The results show that the peak discharge which is divided into first river order was close to observed one. The contour model will provide effective informations to plan river works classified by sub-basins for river restoration.

Development of a Method of Cybersickness Evaluation with the Use of 128-Channel Electroencephalography (128 채널 뇌파를 이용한 사이버멀미 평가법 개발)

  • Han, Dong-Uk;Lee, Dong-Hyun;Ji, Kyoung-Ha;Ahn, Bong-Yeong;Lim, Hyun-Kyoon
    • Science of Emotion and Sensibility
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    • v.22 no.3
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    • pp.3-20
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    • 2019
  • With advancements in technology of virtual reality, it is used for various purposes in many fields such as medical care and healthcare, but as the same time there are also increasing reports of nausea, eye fatigue, dizziness, and headache from users. These symptoms of motion sickness are referred to as cybersickness, and various researches are under way to solve the cybersickness problem because it can cause inconvenience to the user and cause adverse effects such as discomfort or stress. However, there is no official standard for the causes and solutions of cybersickness at present. This is also related to the absence of tools to quantitatively measure the cybersickness. In order to overcome these limitations, this study proposed quantitative and objective cybersickness evaluation method. We measured 128-channel EEG waves from ten participants experiencing visually stimulated virtual reality. We calculated the relative power of delta and alpha in 11 regions (left, middle, right frontal, parietal, occipital and left, right temporal lobe). Multiple regression models were obtained in a stepwise manner with the motion sickness susceptibility questionnaire (MSSQ) scores indicating the susceptibility of the subject to the motion sickness. A multiple regression model with the highest under the area ROC curve (AUC) was derived. In the multiple regression model derived from this study, it was possible to distinguish cybersickness by accuracy of 95.1% with 11 explanatory variables (PD.MF, PD.LP, PD.MP, PD.RP, PD.MO, PA.LF, PA.MF, PA.RF, PA.LP, PA.RP, PA.MO). In summary, in this study, objective response to cybersickness was confirmed through 128 channels of EEG. The analysis results showed that there was a clearly distinguished reaction at a specific part of the brain. Using the results and analytical methods of this study, it is expected that it will be useful for the future studies related to the cybersickness.

Group 1 metabotropic glutamate receptor 5 is involved in synaptically-induced Ca2+-spikes and cell death in cultured rat hippocampal neurons

  • Yang, Ji Seon;Jeon, Sujeong;Jang, Hyun-Jong;Yoon, Shin Hee
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.6
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    • pp.531-540
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    • 2022
  • Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved in synaptically-induced intracellular free Ca2+ concentration ([Ca2+]i) spikes and neuronal cell death induced by 0.1 mM Mg2+ and 10 µM glycine in cultured rat hippocampal neurons from embryonic day 17 fetal Sprague-Dawley rats using imaging methods for Ca2+ and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays for cell survival. Reduction of extracellular Mg2+ concentration ([Mg2+]o) to 0.1 mM induced repetitive [Ca2+]i spikes within 30 sec at day 11.5. The mGluR5 antagonist 6-Methyl2-(phenylethynyl) pyridine (MPEP) almost completely inhibited the [Ca2+]i spikes, but the mGluR1 antagonist LY367385 did not. The group 1 mGluRs agonist, 3,5-dihydroxyphenylglycine (DHPG), significantly increased the [Ca2+]i spikes. The phospholipase C inhibitor U73122 significantly inhibited the [Ca2+]i spikes in the absence or presence of DHPG. The IP3 receptor antagonist 2-aminoethoxydiphenyl borate or the ryanodine receptor antagonist 8-(diethylamino)octyl 3,4,5-trimethoxybenzoate also significantly inhibited the [Ca2+]i spikes in the absence or presence of DHPG. The TRPC channel inhibitors SKF96365 and flufenamic acid significantly inhibited the [Ca2+]i spikes in the absence or presence of DHPG. The mGluR5 antagonist MPEP significantly increased the neuronal cell survival, but mGluR1 antagonist LY367385 did not. These results suggest a possibility that mGluR5 is involved in synaptically-induced [Ca2+]i spikes and neuronal cell death in cultured rat hippocampal neurons by releasing Ca2+ from IP3 and ryanodine-sensitive intracellular stores and activating TRPC channels.

Novel Viterbi Decoding Architecture for DVB-T with Improved Performance in Rayleigh Channels (레일레이 채널에서 성능 향상을 위한 DVB-T용 비터비 디코더의 아키텍쳐)

  • Oh, Jung-Youn;Park, Kyu-Hyun;Lee, Seung-Jun
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.39 no.6
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    • pp.718-726
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    • 2002
  • This paper presents a novel Viterbi decoding architecture for European Digital Video Broadcasting (DVB) receiver. The channel sate information (CSI) of each sub carrier is used to weight the bit-metric of each symbol. The weighted bit-metric is delivered to Viterbi decoder after going through the symbol deinterleaver and bit deinterleaver, such that the CSI can be correctly applied to corresponding bits even after the two interleavings. Simulation shows that the new architecture gives significant performance enhancement of 6~13dB in Rayleigh fading channels depending on the modulation types. This results is also better than previous results by 3.7~10.3dB.

Short-term effects of elevated CO2 on periphyton community in an artificially constructed channel

  • Park, Hye-Jin;Kwon, Dae-Ryul;Kim, Baik-Ho;Hwang, Soon-Jin
    • Journal of Ecology and Environment
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    • v.40 no.1
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    • pp.12-19
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    • 2016
  • Background: Direct impact of inorganic carbon (i.e., carbon dioxide ($CO_2$)) on the periphyton community is important to understand how and to what extent atmospheric conditions can affect the structure and dynamics of these communities in lotic systems. We investigated the influence of elevated $CO_2$ concentration on the periphyton community in the artificially constructed channels during the winter period. The channels made of acrylic paneling were continuously supplied with surface water discharged from a small reservoir, which was supported with ground water, at a flow rate of 5 L/min, and water temperature ranging $4-5^{\circ}C$. The effects of elevated $CO_2$ concentrations (790 ppm) were evaluated in comparison with the control (395 ppm $CO_2$) by analyzing pH, water carbon content and nutrients in water, periphyton composition and biomass, chlorophyll-a, ash-free dry-matter at 2-day intervals for 10 days. Results: After the addition of $CO_2$, significant decreases of pH, $NH_3-N$, and $PO_4-P$ (p < 0.05) and increases of chlorophyll-a, ash-free dry-matter, and the cell density of periphyton (p < 0.01) were observed, whereas the species composition of periphyton and water carbon content did not change. Conclusions: These results suggest that elevated $CO_2$ in flowing water system with low temperature could facilitate the growth of periphyton resulting in biomass increase, which could further influence water quality and the consumers throughout the food web.