• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.93.2-93.2
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• 2012

Point Spread Function (PSF) is one of the most important optical characteristics for describing the performance of a telescope. And a concept of subpixelization is inevitable in evaluating the undersampled PSF (Shin and Sakurai 2009). Then, the internal structure of Yohkoh SXT CCD pixel is not uniform: For the top half of pixel area, the X-ray should pass a so-called gate structure where the charges are transferred to an output amplifier. This gate structure shows energy-dependent sensitivity (Tsuneta et al. 1991). For example, for Al-K (8.34 A) X-ray emission, the transmission of the polysilicon gate is about 0.9. Also, for the peak coronal response of the SXT thin filters, around 17 angstrom (0.729 keV), the transmission of the gate is about 0.6, falling off sharply towards longer wavelengths. It should be noted that this spectrally dependent non-uniform response of each CCD pixel will certainly have a noticeable effect on the properties of the PSF at longer wavelengths. Therefore, especially for analyzing the undersampled PSF of low energy source, a careful consideration of non-uniform internal pixel structure is required in determining the shape of the PSF core. The details on the effect of gate structure will be introduced in our presentation.

• Journal of the Korean Institute of Telematics and Electronics
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• v.13 no.3
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• pp.22-27
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• 1976

For linear IC design, one has to know the epi thickness, resistivity, and structure of buried island inserted between epi and substrate because the mask structure can only be changed for linear IC consisted of various type of transistors to be made for desired specific function. The interrelation of IC operational and saturation voltages with epi resistivity, theckness and divice structure are studied and presented in graphic forms so that IC design engineers can utilize them.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.10
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• pp.45-51
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• 2002

To achieve the lightweight and robust design of a structure, it is requested to design a structure and its control system simultaneously, which is called as the combined optimal design. A constant-cross-sectional area cantilever beam was chosen as an example for the applying the optimum design method. An initial load and a time varying disturbance were applied at the free end of the beam. Sliding mode control was selected due to its insensitiveness to the disturbance compared with other modes. It is known that the sliding mode control is robust to the disturbance and the uncertainty only if a matching condition is met, after giving a switching hyper plane. In this study, the optimum method was used for the design of the switching hyper plane and the objective function of the optimum switching hyper plane was assumed to be the objective one of the control system. The total weight of the structure was treated as a constraint and the cross sectional areas of the beam were considered as design variables, which means a nonlinear programming problem. The sequential linear programming method was applied to solve it. As a result of the optimum design, the effect of attenuating vibrations has been improved obviously. Moreover, lightweight design of the structure became possible from the relationship of the weight of the structure and the control objective function.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.13 no.12
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• pp.930-937
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• 2003

This research deals with how to select connection positions of two substructures to be synthesized. The goal of this research is to find optimal connection positions in order to maximize the fundamental natural frequency of the synthesized structure. The natural frequencies of a connected structure are obtained by modal-force equations. Optimal connection positions can be selected through optimization process. In the optimization process, the natural frequencies of a connected structure are set to object function value and connection positions become design variables. The method described above is applied to synthesis problems of plates, which is initially conducted for FE models and verified through experiments. Especially in experiments. FRF(frequency response function) s are obtained by means of the Modal Testing technique to be used in modal-force equations for synthesizing. Once the substructures are synthesized. the Modal Testing technique is again applied to spot-welded structure using the result from the optimization procedure. It is found that the fundamental natural frequency of the synthesized structure with the optimized result gives higher value than those with the initially given connection positions.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.65-71
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• 2003

This research deals with how to select connection positions of two substructures to be synthesized. The goal of this research is to find optimal connection positions in order to maximize the fundamental natural frequency of the synthesized structure. The natural frequencies of a connected structure are obtained by modal-force equations. Optimal connection positions can be selected through optimization process. In the optimization process, the natural frequencies of a connected structure are set to object function value and connection positions become design variables. The method described above is applied to synthesis problems of plates, which is initially conducted for FE models and verified through experiments. Especially in experiments, FRE(frequency Response function)s are obtained by means of the Modal Testing technique to be used in modal-force equations for synthesizing. Once the substructures are synthesized, the Modal Testing technique is again applied to spot-welded structure using the result from the optimization procedure. It is found that the fundamental natural frequency of the synthesized structure with the optimized result gives higher value than those with the initially given connection positions.

• Geomechanics and Engineering
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• v.17 no.6
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• pp.565-572
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• 2019

Spatial variability is an inherent characteristic of soil, and auto-correlation length (ACL) is a very important parameter in the reliability or probabilistic analyses of geotechnical engineering that consider the spatial variability of soils. Current methods for estimating the ACL need a large amount of laboratory or in-situ experiments, which is a great obstacle to the application of random field theory to geotechnical reliability analysis and design. To estimate the ACL reasonably and efficiently, we propose a micro-structure based numerical simulation method. The quartet structure generation set algorithm is used to generate stochastic numerical micro-structure of soils, and scanning electron microscope test of soil samples combined with digital image processing technique is adopted to obtain parameters needed in the QSGS algorithm. Then, 2-point correlation function is adopted to calculate the ACL based on the generated numerical micro-structure of soils. Results of a case study shows that the ACL can be estimated efficiently using the proposed method. Sensitivity analysis demonstrates that the ACL will become stable with the increase of mesh density and model size. A model size of $300{\times}300$ with a grid size of $1{\times}1$ is suitable for the calculation of the ACL of clayey soils.

• BMB Reports
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• v.41 no.6
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• pp.444-447
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• 2008

Trypanothione reductase is an important target enzyme for structure-based drug design against Leishmania. We used homology modeling to construct a three-dimensional structure of the trypanothione reductase (TR) of Leishmania infantum. The structure shows acceptable Ramachandran statistics and a remarkably different active site from glutathione reductase(GR). Thus, a specific inhibitor against TR can be designed without interfering with host (human) GR activity.

• BMB Reports
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• v.33 no.3
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• pp.195-201
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• 2000

A human gene has been reported that may encode the enzyme acetohydroxyacid synthase. Previously this enzyme was thought to be absent from animals although it is present in plants and many microorganisms. In plants, this enzyme is the target of a number of commercial herbicides and the use of these compounds may need to be reassessed if the human enzyme exists and proves to be susceptible to inhibition. Here we report the construction of several plasmid vectors containing the cDNA sequence for this protein, and their expression in Escherichia coli. High levels of expression were observed, but most of the protein proved to be insoluble. The small amounts of soluble protein contained little or no acetohydroxyacid synthase activity. Attempts to refold the insoluble protein were successful insofar as the protein became soluble. However, the refolded protein did not gain any acetohydroxyacid synthase activity. In vivo complementation tests of an E. coli mutant produced no evidence that the protein is active. Incorrect folding, or the lack of another subunit, may explain the data but we favor the interpretation that this gene does not encode an acetohydroxyacid synthase.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.3
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• pp.63-71
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• 2007

During the design phase of a product, reliability and design engineers are called upon to evaluate the reliability of the system, The question of how to meet target reliability for the system arises when estimated reliability or cost is inadequate. This then becomes a problem of reliability allocation and system structure design. This study proposes the optimization methodology to achieve target reliability with minimum cost through construction of the cost function of system. In cost function, total cost means the sum of initial cost, repair cost and maintenance cost. This study constructs optimization problem about system structure design and reliability allocation using cost function. This problem constructed is solved by Multi-island Genetic Algorithm(MIGA), and applies to urban transit brake system. Current brake system of the urban transit is series system. Series system is the simplest and perhaps one of the most common system, but it demands high reliability and maintenance cost because all components must be operating to ensure system operation. Thus this study makes a comparative study by applying k-out-of-n system to brake system. This methodology presented can be a great tool for aiding reliability and design engineers in their decision-makings.

• Journal of the Society of Naval Architects of Korea
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• v.45 no.2
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• pp.192-201
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• 2008

The design process becomes more difficult due to the increasing complexity of products. Thus, without any proper design experience, designer cannot handle his design problems systematically. Besides, the conventional optimal design method cannot be used effectively at the early design stage, since most design problems must be formulated in terms of objective and constraint functions based on the mathematical concepts of Operation Research. Thus, in this paper, new design concept based on FBS (Function-Behavior-Structure) design model is introduced to help the novice designer formulate the complex design problems systematically into a mathematical form. In this FBS model, function means the designer's new intents designer wants to create for, structure stand for a final product configuration and behaviour is a product's performance. FBS design model is thus rather totally different concept used for formulating design problem, compared with conventional optimal design method. To validate this new FBS model, 330K VLCC design case is performed, and we found, though it is one design example case, that this new design concept could be effectively used for future ship design problems since, during the formulating design problem, the only engineering terminology such as function, structure, and behaviour of design product is used based on the engineering concepts, instead of mathematical terminology such as objective and constraints.