• Title/Summary/Keyword: Structure elucidation

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Synthesis of Some Novel N7-tetrazolo[5,1-f]-1,2,4-triazin-8-(7H)-one Compounds as Potential Antimicrobial Agents

  • El-Badry, Susan M.;Taha, Mamdouh A.M.
    • Journal of the Korean Chemical Society
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    • v.58 no.4
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    • pp.381-387
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    • 2014
  • A series of new $N^7$-tetrazolo[5,1-f ]-1,2,4-triazin-8-(7H)-one derivatives 4-16 were designed and synthesized from 3 with different reagents. The newly prepared compounds were characterized by spectral data and screened for their antimicrobial activities against various bacteria and fungi strains.

Taxoids from the Heartwood of Taxus baccata L. Growing in Turkey

  • Erdemoglu, Nurgun;Sener, Bilge
    • Natural Product Sciences
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    • v.6 no.2
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    • pp.96-101
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    • 2000
  • The ethanolic extract of the heartwood of Taxus baccata L. afforded six taxoids, belonging to the skeletally three different groups, $2{\alpha},\;5{\alpha},\;10{\beta}-triacetoxy-14{\beta}-(2-methyl)-butryloxy-4(20)$,11-taxadiene (1), taxusin (2), baccatin VI (3), baccatin III (4), $1{\beta}-hydroxybaccatin$ I (5) and taxol (6). The isolation and structure elucidation of three taxoids (3-5) have been presented in this study. This is the first report for the presence of these taxoids in Taxus baccata L. growing in Turkey.

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Analytical Separation of Isomeric Saponins by LC/MS

  • Young, Han-Suk;Park, Jong-Cheol;Choi, Jae-Sue
    • Korean Journal of Pharmacognosy
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    • v.19 no.4
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    • pp.248-250
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    • 1988
  • The application of LC/MS system with FRIT-FAB LC/MS interface in both positive and negative ion modes to the analytical separation of isomeric saponins was studied. The two isomeric saponins such as rosamultin and arjunetin were well separated and analyzed FRIT, FAB LC/MS system. This is another examples to structure elucidation of natural products.

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Structure Elucidation for New Sestertepene Alkaloids from the Sponge Sacotragus sp.

  • Rho, Jung-Rae;Shin, Jong-Heon;Lee, Hyi-Seung
    • Journal of the Korean Magnetic Resonance Society
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    • v.7 no.1
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    • pp.55-61
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    • 2003
  • Sarcotragins C(1) and D(2), two novel compounds, have been isolated from the sponge Sarcotragus sp. collected from Jaeju Island, Korea. The structures of these compounds have been determined to be linear sesterterpene alkaloids on the basis of combined 1D and 2D NMR experiments. The stereochemistry involved was established by comparison of the NMR data with those reported for a similar compound.

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Sesquiterpenoids from the Rhizome of Curcuma zedoaria

  • Hong, Chai-Hee;Kim, Young-heem;Lee, Sang-Kook
    • Archives of Pharmacal Research
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    • v.24 no.5
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    • pp.424-426
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    • 2001
  • In the course of searching for biologically active sesquiterpenoids from Curcuma genus, two sesquiterpenoids were isolated from the rhizome of Curcuma zedoaria (Zingiberaceae). Their structures were identified as ar-turmerone (1) and $\beta$-turmerone (2). The structure elucidation of compounds 1 and 2 was carried out by comparison of their physical and spectral data with previously reported values.

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Isolation and Structure Elucidation of Flavonoid Glycosides from Lindera obtusiloba BL. (생강나무에서 분리한 Flavonoid 배당체의 화학구조)

  • 박종철;유영법;이종호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.1
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    • pp.76-79
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    • 1996
  • 생강나무 (Libdera obtusiloba BL.)의 페놀성 화합물들을 분리하기 위하여 잎고 줄기의 MeOH 엑스로부터 계통 분획한 EtOAc 분획물은 silica gel column chro-matography로 분리하여 2종의 화합물을 얻었다. IR, UV,$^1H-NMR$, $^13C-NMR$ 등의 분석을 행하여 화학구조를 밝힌 결과 이들 화합물의 화학구조는 잎에서 $quer-cetin-3-O-\alpha-L-rhamnopyranoside(quercitrin),$ 줄기에서는 quercetin $3-O-\beta-D-galactoyranoside(hyperoside)로$ 각각 결정하였다. 이 화합물들은 생강나무에서 처음으로 분리하였다.

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Chemical Constituents of Pulicaria gnaphalodes

  • Ali, Muhammad Shaiq;Jahangir, Muhammad;Saleem, Muhammad;Ahmad, Viqar Uddin
    • Natural Product Sciences
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    • v.5 no.3
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    • pp.134-137
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    • 1999
  • The chloroform extract of Pulicaria gnaphalodes yielded flavonoids (1-2), sesquiterpenoid (3), sterol (4), benzoic acid derivative (5) and fatty acids (6-7). Their structures were elucidated with the aid of NMR spectroscopy. The described compounds have not been reported so far from this source.

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NMR PEAK ASSIGNMENT FOR THE ELUCIDATION OF THE SOLUTION STRUCTURE OF T4 ENDONUCLEASE V

  • Im, Hoo-Kang;Jee, Jun-Goo;Yu, Jun-Suk;Lee, Bong-Jin
    • Proceedings of the Korean Biophysical Society Conference
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    • 1996.07a
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    • pp.18-18
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    • 1996
  • Bacteriophage T4 endonuclease V initiates the repair of ultraviolet (UV)-induced pyrimidine dimer photoproducts in duplex DNA. The mechanism of DNA strand cleavage involves four sequential steps: linear diffusion along dsDNA, pyrimidine dimer-specific binding, pyrimidine dimer-DNA glycosylase activity, and AP lyase activity. (omitted)

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