• 융합보안논문지
• /
• 제14권6_1호
• /
• pp.3-12
• /
• 2014

본 연구는 우수 장교양성을 목적으로 시행중인 군사학과 학생들의 자질과 품성 함양을 위한 훈육교수의 역할과 훈육을 담당하는 교수의 핵심역량을 어떻게 어떤 항목으로 할 것인가와 이를 개발하기 위한 역량 모델을 제시하고자 하였다. 이 연구를 통하여 군사학과 교육운영체계의 전반적인 발전방안을 제시하는데 그 목적이 있다. 이와 같은 연구목적을 달성하기 위해 본 연구는 기존 훈육의 개념에 대한 선행연구와 이론을 기초로 발전방안을 제시하였다. 여기에 제시된 내용은 사관학교 위주의 선행연구를 기초로 하여 훈육요원에게 필요한 핵심 역량인 교수 평가 생활 지도 학급경영 역량을 일반적 운영절차에 따라 계획 준비 실시 성과분석단계로 구분하여 어떻게 진행하고 조치할 것인가에 대한 모델을 제시했다는데 의의가 있으며 여기서 제시한 연구결과는 일반대학 군사학과의 훈육담당 교수의 역할과 역량을 효율적으로 발휘하기 위한 모델을 제시하기 위해 연구되었다. 훈육에 관련된 모델은 사관학교에서 부분적으로 연구되었으나 본 연구는 민간대학 군사학과 학생들의 훈육을 담당하는 교수들의 역량을 효율적으로 극대화하기 위한 모델을 제시했다는데 그 의의가 있다. 그러나, 여기서 제시한 모델은 최근 군 교육기관에서 연구된 일부 내용들과 일반적인 훈육관련 선행연구들을 기초로 만들어진 모델이기 때문이 이것을 모든 대학이 그대로 적용하기에는 약간의 제한 사항들이 도출될 수 있다. 따라서 이 연구를 출발점으로 하여 민간대학 군사학과 훈육담당 교수들이 이 모델을 기초로 하여 실증적인 검증과 보완이 필요하고 지속적인 분석과 보완이 되어야 할 것이다.

• 한국정보시스템학회지:정보시스템연구
• /
• 제21권3호
• /
• pp.71-97
• /
• 2012

There has been an upward trend in smartphone sales in Korea as well as the rest of the world. Even though smartphones are now at the peak of their popularity, the fact that they are somewhat limited in terms of their usages for certain purposes is unexpected. Precisely, compared to PC, smartphones typically have smaller display screens with a lower resolution, which make them difficult to use in general. For instance, when customers search the information about products in mobile shopping malls, due to the smaller screen with a low resolution smartphone users may realize that it is not easy and convenient not only to search the information, but also to read the information they found in the shopping malls. This restriction could become one of reasons that lowers the perceived quality of information in the shopping malls, which in turn leads to the reluctance to use the shopping malls. A comprehensive information systems (IS) literature review found that there has been little empirical evidence on perceived information quality that affects smartphone users' intention to use mobile shopping malls. The purposes of this study is to examine 1) the effects of perceived information quality on smartphone users' intention to use mobile shopping malls and 2) the relationships among behavioral beliefs in the middle of independent and dependent variables, such as information satisfaction, perceived usefulness, and customers' attitude toward mobile shopping. A survey was conducted in March 2012. College students and practitioners took participated in the survey. Structural Equation Modeling(SEM) was used for all data analysis. The results found that there is a strong relationship between perceived information quality and smartphone users' intention to use mobile shopping malls. In addition, this study also showed that there are strong relationships among behavioral beliefs. Further research is expected to validate the findings of this study and apply them in specific contexts.

• Applied Microscopy
• /
• 제43권1호
• /
• pp.21-26
• /
• 2013

The oriental fruit moth (Grapholita molesta Busck) and the peach fruit moth (Carposina sasakii Matsumura) are the most severe insect pests affecting apple orchards in Korea. To prevent an outbreak of these two species and to control these agricultural insect pests, it is important to identify them accurately. However, it is hard to classify them when they were in the larval stage since they tunnel into the apple fruit. In this study, surface structures of the two species of larvae were observed using stereo microscope and scanning electron microscope. Distinct differences between the two species of larvae were found. The prothorax spiracles of oriental fruit moth larvae were approximately twice as large as those of peach fruit moth larvae. The arrangements of subventral setae, located around the proleg, were different between oriental fruit moth and peach fruit moth larvae. Furthermore, subdorsal setae of oriental fruit moth were located next to the spiracle on the 8th abdominal segment, while that of peach fruit moth was located above the spiracle. The identification of the two species of larvae observed in this study was confirmed using polymerase chain reaction-restriction fragment length polymorphism method. Surface structural differences are intrinsic characteristics for each species of larvae and can easily be identified using stereo microscope. These specificities will be helpful where a large number of field-collected larvae need to be identified routinely in pest control research.

• Molecules and Cells
• /
• 제27권6호
• /
• pp.673-680
• /
• 2009

Conversion of the normal soluble form of prion protein, PrP ($PrP^C$), to proteinase K-resistant form ($PrP^{Sc}$) is a common molecular etiology of prion diseases. Proteinase K-resistance is attributed to a drastic conformational change from ${\alpha}$-helix to ${\beta}$-sheet and subsequent fibril formation. Compelling evidence suggests that membranes play a role in the conformational conversion of PrP. However, biophysical mechanisms underlying the conformational changes of PrP and membrane binding are still elusive. Recently, we demonstrated that the putative transmembrane domain (TMD; residues 111-135) of Syrian hamster PrP penetrates into the membrane upon the reduction of the conserved disulfide bond of PrP. To understand the mechanism underlying the membrane insertion of the TMD, here we explored changes in conformation and membrane binding abilities of PrP using wild type and cysteine-free mutant. We show that the reduction of the disulfide bond of PrP removes motional restriction of the TMD, which might, in turn, expose the TMD into solvent. The released TMD then penetrates into the membrane. We suggest that the disulfide bond regulates the membrane binding mode of PrP by controlling the motional freedom of the TMD.

• 한국강구조학회 논문집
• /
• 제24권1호
• /
• pp.109-117
• /
• 2012

연구대상은 콘크리트 충전강관 (Concrete Filled steel tube)기둥과 보의 접합부를 합성반강접으로 적용한 구조물의 설계 적용에 관한 것이다. 합성반강접으로 기둥접합부의 강성을 조절함으로서 구조적 안전성을 확보하고 경제적인 부재를 적용하고자 하였다. 저층건물을 모멘트골조로 구조물의 안정성을 검토한 결과 합성작용으로 인하여 합성반강접을 이용하면 횡강성이 증대하여 저층건물의 경우 특별한 횡 보강재 없이 저항할 수 있음을 확인 하였다. 고층건물의 경우 모멘트골조가 횡저항 분담이 10%정도 되었으며 반강접 비율은 60%정도가 적절하였다. 경제적인 면에서 보 부재는 등분포하중이 작용하는 경우는 반강접 효과가 크나 집중하중이 작용하는 보는 반강접 효과가 크지 않았으며 등분포의 경우 60% 반강접이 단부 모멘트 저감에 따른 경제성이 가장 좋은 것으로 분석되었다. 단부 모멘트는 약 25% 감소되는 것을 확인 할 수 있었다.

• 한국식물학회:학술대회논문집
• /
• 한국식물학회 1995년도 제9회 식물생명공학 심포지움 식물육종과 분자생물학의 만남 The 9th Plant Biotechnology Symposium -Breeding and Molecular Biology-
• /
• pp.57-86
• /
• 1995

Molecular mapping of plant genomes has progressed rapidly since Bostein et al.(1980) introduced the idea of constructing linkage maps of human genome based on restriction fragment length polymorphism (RFLP) markers. In recent years, the development of protein and DNA markers has stimulated interest for the new approaches to plant improvement. While classical maps based on morphological mutant markers have provided important insights into the plant genetics and cytology, the molecular maps based on molecular markers have a number of inherent advatages over classical genetic maps for the applications in genetic studies and/or breeding schemes. Isozymes and DNA markers are numerous, discrete, non-deleterious, codominant, and almost entirely free of environmental and epistatic interactions. For these reasons, they are widely used in constructing detailed linkage maps in a number of plant species. Plant breeders improve crops by selecting plants with desirable phenotypes. However a plant's phenotyes is often under genetic control, positioning at different "quantitative trait loci" (QTLs) together with environmental effects. Molecular maps provide a possible way to determine the effect of the individual gene that combines to produce a quantitative trait because the segregation of a large number of markers can be followed in a single genetic cross. Using market-assisted selection, plants that contain several favorable genes for the trait and do not contain unfavourable segments can be obtained during early breeding processes. Providing molecular maps are available, valuable data relevant to the taxonomic relationships and chromosome evolution can be accumulated by comparative mapping and also the structural relationships between linkage map and physical map can be identified by cDNA sequencing. After constructing high density maps, it will be possible to clone genes, whose products are unknown, such as semidwarf and disease resistance genes. However, much attention has to be paid to level-up the basic knowledge of genetics, physiology, biochemistry, plant pathology, entomology, microbiology, and so on. It must also be kept in mind that scientists in various fields will have to make another take off by intensive cooperation together for early integration and utilization of these newly emerging high-techs in practical breeding. breeding.

• Industrial Engineering and Management Systems
• /
• 제8권3호
• /
• pp.194-200
• /
• 2009

This study provides a heuristic algorithm to solve the locating problem of repair service centers (RSCs). To enhance the customer service level with more satisfaction and quicker responsiveness, the locating problem of RSCs has become one of the important issues in reverse supply chain management. This problem is formulated as a zero-one mixed integer programming in which an exiting distributor will be considered to be an un-capacitated repair service center for the objective of cost-minimizing. Since logistical costs are highly interrelated with the multinational location of distributors and RSCs, the fixed cost for setting a repair service center, variable cost, transportation cost, and exchange rates are considered in this study. Recognizing the selection of un-capacitated RSCs' locations is a combinatorial optimization problem and is a zero-one mixed integer programming with NP-hard complexity, we provide a heuristic algorithm named as incremental cost matrix procedure (ICMP) to simplify the solving procedure. By using the concise and structural cost matrix, ICMP can efficiently screen the potential location with cost advantage and effectively decide which distributor should be a RSC. Results obtained from the numerical experiments conducted in small scale problem have shown the fact that ICMP is an effective and efficient heuristic algorithm for solving the RSCs locating problem. In the future, using the extended ICMP to solve problems with larger industrial scale or problems with congestion effects caused by the variation of customer demand and the restriction of the RSC capacity is worth a further investigation.

• 한국발생생물학회지:발생과생식
• /
• 제22권3호
• /
• pp.263-273
• /
• 2018

Aquaporin (AQP) 3, a facilitated transporter of water and glycerol, expresses in placenta and fetal membranes, but the detailed localization and function of AQP3 in placenta remain unclear. To elucidate a role of AQP3 in placenta, we defined the expression and cellular localization of AQP3 in placenta and fetal membranes, and investigated the structural and functional differences between wild-type and AQP3 null mice. Gestational sacs were removed during mid-gestational period and amniotic fluid was aspirated for measurements of volume and composition. Fetuses with attached placenta and fetal membranes were weighed and processed for histological assessment. AQP3 strongly expressed in basolateral membrane of visceral yolk sac cells of fetal membrane, the syncytiotrophoblasts of the labyrinthine placenta and fetal nucleated red blood cell membrane. Mice lacking AQP3 did not exhibit a significant defect in differentiation of trophoblast stem cells and normal placentation. However, AQP3 null fetuses were smaller than their control litter mates in spite of a decrease in litter size. The total amniotic fluid volume per gestational sac was reduced, but the amniotic fluid-to-fetal weight ratio was increased in AQP3 null mice compared with wild-type mice. Glycerol, free fatty acid and triglyceride levels in amniotic fluid of AQP3 null mice were significantly reduced, whereas lactate level increased when compared to those of wild-type mice. These results suggest a role for AQP3 in supplying nutrients from yolk sac and maternal blood to developing fetus by facilitating transport of glycerol in addition to water, and its implication for the fetal growth in utero.

• 한국터널지하공간학회 논문집
• /
• 제9권4호
• /
• pp.387-401
• /
• 2007

최근 용지매입의 제한, 주변 구조물과의 간섭 등으로 두 터널의 이격거리가 매우 작은 근접 병설터널의 시공이 증가하고 있다. 이러한 경우 터널의 안정성뿐만 아니라 중앙 필라부의 안정성 확보를 위한 보강공법의 선정은 매우 중요한 문제라 할 수 있다. 본 연구에서는 상 하행선의 터널단면이 다른 비대칭 형태이면서, 두 터널간의 이격거리가 매우 근접한 병설터널에 대한 안정성 평가 및 필라부 보강방안에 대하여 상세한 해석적 검토를 수행하였다. 또한 근접 병설터널의 안정성을 확보할 수 있도록 암반 필라의 안정성 검토와 보강공법 등 근접 병설터널의 사례연구를 토대로 보강공법의 적정성과 합리적인 대안을 제시하였다. 특히, 굴착순서, 이격거리, 굴착방법에 따른 터널 거동 파악을 위하여 암반 필라의 응력상태 및 터널변위를 분석하여 암반파괴이론에 근거한 안정성 평가를 수행하였다. 또한 암반 필라부 보강공법의 적정성 검토 및 향후 근접병설 터널에서의 암반 필라 안정성 확보를 위한 개선방안을 제안하였다

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권7호
• /
• pp.2971-2974
• /
• 2015

TP53 is assumed to be a very important tumour suppressor gene, as illustrated by recent reports that have shown effects of its polymorphisms on breast cancer risk. Arg72Pro and PIN3(16bp duplication) polymorphisms are proposed to have an effective role in structural changes of p53 and have therefore attracted interest as a risk factor for breast cancer in different populations. The aim of this study was to examine and determine whether p53 codon 72 and PIN3 Ins16 bp may be associated with an increased risk for breast cancer in female patients from the northwest of Iran. Genotyping was performed by PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) method for a total of 100 women with breast cancer and 100 healthy women without any background of cancer, focusing on the TP53 Arg72Pro-16Del/Ins haplotypes and the combined genotypes. The results in this study established no statistical significant distinctions between the genotypes and a llele frequency were found for Arg72Pro and PIN3 Ins 16 bp polymorphisms between patients and controls.