• Bulletin of the Korean Chemical Society
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• 제35권12호
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• pp.3542-3546
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• 2014

Relationship between molecular freedom of amyloidogenic protein and its self-assembly into amyloid fibrils has been evaluated with ${\alpha}$-synuclein, an intrinsically unfolded protein related to Parkinson's disease, by restricting its structural plasticity through an end-to-end disulfide bond formation between two newly introduced cysteine residues on the N- and C-termini. Although the resulting circular form of ${\alpha}$-synuclein exhibited an impaired fibrillation propensity, the restriction did not completely block the protein's interactive core since co-incubation with wild-type ${\alpha}$-synuclein dramatically facilitated the fibrillation by producing distinctive forms of amyloid fibrils. The suppressed fibrillation propensity was instantly restored as the structural restriction was unleashed with ${\beta}$-mercaptoethanol. Conformational flexibility of the accreting amyloidogenic protein to pre-existing seeds has been demonstrated to be critical for fibrillar extension process by exerting structural adjustment to a complementary structure for the assembly.

• 복식
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• 제58권9호
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• pp.166-175
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• 2008

For the structural firefighting protective clothing, it can show a synergy effect when it satisfies smart fabric to block off a harmful environmental element and ergonomics design that apply range of motion of human body and appropriate size system. There are various standards about the structural firefighting protective clothing, but it's difficult to find a rule about movement suitability because the performance of the material holds a lot of the rules. Therefore, the purpose of this study is to propose a scheme to evaluate the current structural firefighting protective clothing and to improve movement suitability by research on the actual condition. For this, the survey about wearer acceptability scale on design and size and about improvement requirements was executed gathering firefighters' opinion. Questionnaire was composed with 23 items about satisfaction on current structural firefighting protective clothing, body suitability, movement suitability, improvement requirement and subjective information. As a results, Korean firefighters demand ergonomics design of structural firefighting protective clothing which to minimize restriction of body movement and to maximize body suitability.

• 약학회지
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• 제39권1호
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• pp.6-9
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• 1995

The clinical isolate Staphylococcus aureus SA2 had four kinds of plasmids and was resistant to ampicillin, chloramphenicol, clindamycin, erythromycin, gentamicin, kanamycin, methicillin, streptomycin, tetracycline and tobramycin. Transformation experiment demonstrated that 4.44 kb plasmid(pKH6) encoded resistance to tetracycline. The cleavage map of pKH6 was determined by restriction enzyme mapping techniques. The cleavage map is given for EcoRV, HindIII, HpaI, HpaII, KpnI and Xbal. Restriction endonucleases BamHl, BglI, BGIII, BstEII, EcoRI, HaellI, PstI, PvuII, SalI, Smal, and Xhol have no site on this plasmid. The restriction map revealed extensive structural homology between pKH6 and pT181.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1997년도 가을 학술발표회 논문집
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• pp.539-545
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• 1997

Since the length of massive wall-structure is generally longer and larger than its thickness and a lift height of concrete of placement, cracks induced by hydration heat are governed by outer structural restriction rather than inner one. However, the degree of restriction control is expected to be affected by the sizes of wall thickness, length and a lift height. Thus, this analytical study aims at the development of relationship among those to minimize thermal cracks. In addition, the effect of types of cement on the thermal heats and stresses is evaluated for anti-sulphate and 2blended Portland cements concrete. It was found from analytical study that a lift height of concrete placement is the most important factor controlling thermal cracks, and the increase of lift heights is not always detrimental to structural safety.

• 아동학회지
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• 제26권6호
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• pp.351-365
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• 2005

This study investigated causal relations between mother's parenting, self-efficacy, perceived social support, stress, and parenting behaviors, Child's temperament, and the mediational role of mother's parenting self-efficacy. Participants were 404 Korean children and their mothers living in Seoul, Korea. Results showed that mother's parenting self-efficacy was positively related to mother's Warmth-Acceptance, social support, and child's temperament. On the other hand, mother's parenting self-efficacy was negatively related to. mother's Rejection-Restriction, mother's Permissiveness-Nonintervention, and mother's stress. Structural equation modeling indicated that mother's parenting self-efficacy was a significant mediator of the relation between mother's perceived social support and stress, child's temperament, and mother's parenting behaviors including Warmth-Acceptance, Rejection-Restriction and Permissiveness-Nonintervention Child's temperament had an indirect effect on mother's Rejection-Restriction and Permissiveness Nonintervention.

• 대한가정학회지
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• 제44권11호
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• pp.79-89
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• 2006

This study investigated the relations between mother's parenting self-efficacy, perceived social support, parenting behavior, and stress, and child's temperament, and child' self-esteem, including a mediational role of Korean mother's parenting self-efficacy. The participants were 404 Korean child-mother dyads living in Seoul, Korea. Structural equation modeling indicated that mother's parenting self-efficacy was a significant mediator of the relation between mother's perceived social support and child's temperament and mother's parenting behaviors including Warmth-Acceptance, Rejection-Restriction, and Permissiveness-Nonintervention. In the Warmth-Acceptance model, mother's parenting self-efficacy was related to child self-esteem through Warmth-Acceptance. In the Rejection-Restriction model, mother's parenting self-efficacy was related to child self-esteem both directly and through Rejection-Restriction. Child's temperament was also related to Rejection-Restriction directly. In the Permissiveness-Nonintervention model, mother's parenting self-efficacy was related to child self-esteem directly, not through Permissiveness-Nonintervention. Child's temperament, also, was related to Permissiveness-Nonintervention directly.

• 응용통계연구
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• 제24권5호
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• pp.799-807
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• 2011

본 연구에서는 기존의 벡터자기회귀모형에서 내생변수의 충격을 식별 가능하도록 모형의 당기 구조교란항 계수행렬에 사전 제약을 가해, 외생적 충격에 대한 변수들의 장단기 동적 반응을 추적해 보았다. 구조형 모형에 특정 이론에 의거하지 않고 현실상황에 상응한다고 판단되는 식별제약을 설정하여 추정하고 각 변수의 변동에서 각 구조적 충격이 차지하는 상대적 중요도를 계산하였다. 분석결과는 식별제약 및 모형의 추정결과와 일관성을 유지하는 것으로 판명되었다.

• 한국토양비료학회지
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• 제49권2호
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• pp.144-156
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• 2016

Soil is a dynamic biological system, in which it is difficult to determine the composition of microbial communities. Knowledge of microbial diversity and function in soils are limited because of the taxonomic and methodological limitations associated with studying the organisms. In this review, approaches to measure microbial diversity in soil were discussed. Research on soil microbes can be categorized as structural diversity, functional diversity and genetic diversity studies, and these include cultivation based and cultivation independent methods. Cultivation independent technique to evaluate soil structural diversity include different techniques such as Phospholipid Fatty Acids (PLFA) and Fatty Acid Methyl Ester (FAME) analysis. Carbon source utilization pattern of soil microorganisms by Community Level Physiological Profiling (CLPP), catabolic responses by Substrate Induced Respiration technique (SIR) and soil microbial enzyme activities are discussed. Genetic diversity of soil microorganisms using molecular techniques such as 16S rDNA analysis Denaturing Gradient Gel Electrophoresis (DGGE) / Temperature Gradient Gel Electrophoresis (TGGE), Terminal Restriction Fragment Length Polymorphism (T-RFLP), Single Strand Conformation Polymorphism (SSCP), Restriction Fragment Length Polymorphism (RFLP) / Amplified Ribosomal DNA Restriction Analysis (ARDRA) and Ribosomal Intergenic Spacer Analysis (RISA) are also discussed. The chapter ends with a final conclusion on the advantages and disadvantages of different techniques and advances in molecular techniques to study the soil microbial diversity.

• Structural Engineering and Mechanics
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• 제53권1호
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• pp.89-104
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• 2015

In current bridge management systems (BMSs), load and speed restrictions are applied on unhealthy bridges to keep the structure safe and serviceable for as long as possible. But the question is, whether applying these restrictions will always decrease the internal forces in critical components of the bridge and enhance the safety of the unhealthy bridges. To find the answer, this paper for the first time in literature, looks into the design aspects through studying the changes in demand by capacity ratios of the critical components of a bridge under the train loads. For this purpose, a structural model of a simply supported bridge, whose dynamic behaviour is similar to a group of real railway bridges, is developed. Demand by capacity ratios of the critical components of the bridge are calculated, to identify their sensitivity to increase of speed and magnitude of live load. The outcomes of this study are very significant as they show that, on the contrary to what is expected, by applying restriction on speed, the demand by capacity ratio of components may increase and make the bridge unsafe for carrying live load. Suggestions are made to solve the problem.

• 대한가정학회지
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• 제45권5호
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• pp.63-74
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• 2007

As the number of North Koreans defectors entering South Korea with their family members increases, it becomes more important to explore the family characteristics that facilitate their adjustment. The data used in the present study was collected from a survey of 195 North Korean defectors. The aim of this study was to investigates how the structural and relational aspects of family influence the socio-cultural adjustment of North Korean defectors. The structural characteristics of family life included whether or not the defectors exited with their family members, whether they were living with family members, and whether they were living with family members under the age of 18. The relational characteristics included family cohesion and adaptability. The study results showed that living with young family members was negatively associated with the social activity restriction problems commonly perceived by North Korean defectors. Family cohesion was also negatively associated with the social activity restriction problems and positively associated with the social isolation problems. The results of this study also showed that family adaptability was not significantly associated with any socio-cultural adjustment problems.