• Structural Engineering and Mechanics
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• v.29 no.5
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• pp.505-530
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• 2008

This paper proposes the application of active multiple tuned mass dampers (AMTMD) for translational and torsional response control of a simplified two-degree-of-freedom (2DOF) structure, able to represent the dynamic characteristics of general asymmetric structures, under the ground acceleration. This 2DOF structure is a generalized 2DOF system of an asymmetric structure with predominant translational and torsional responses under earthquake excitations using the mode reduced-order method. Depending on the ratio of the torsional to the translational eigenfrequency, i.e. the torsional to translational frequency ratio (TTFR), of asymmetric structures, the following three cases can be distinguished: (1) torsionally flexible structures (TTFR < 1.0), (2) torsionally intermediate stiff structures (TTFR = 1.0), and (3) torsionally stiff structures (TTFR > 1.0). The even distribution of the AMTMD within the whole width and half width of the asymmetric structure, thus leading to three cases of installing the AMTMD (referred to as the AMTMD of case 1, AMTMD of case 2, AMTMD of case 3, respectively), is taken into account. In the present study, the criterion for searching the optimum parameters of the AMTMD is defined as the minimization of the minimum values of the maximum translational and torsional displacement dynamic magnification factors (DMF) of an asymmetric structure with the AMTMD. The criterion used for assessing the effectiveness of the AMTMD is selected as the ratio of the minimization of the minimum values of the maximum translational and torsional displacement DMF of the asymmetric structure with the AMTMD to the maximum translational and torsional displacement DMF of the asymmetric structure without the AMTMD. By resorting to these two criteria, a careful examination of the effects of the normalized eccentricity ratio (NER) on the effectiveness and robustness of the AMTMD are carried out in the mitigation of both the translational and torsional responses of the asymmetric structure. Likewise, the effectiveness of a single ATMD with the optimum positions is presented and compared with that of the AMTMD.

• Structural Engineering and Mechanics
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• v.63 no.5
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• pp.617-628
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• 2017

In order to study the failure mode and seismic behavior of the interior-joint in steel traditional-style buildings, a single beam-column joint and a double beam-column joint were produced according to the relevant building criterion of ancient architectural buildings and the engineering instances, and the dynamic horizontal loading test was conducted by controlling the displacement of the column top and the peak acceleration of the actuator. The failure process of the specimens was observed, the bearing capacity, ductility, energy dissipation capacity, strength and stiffness degradation of the specimens were analyzed by the load-displacement hysteresis curve and backbone curve. The results show that the beam end plastic hinge area deformed obviously during the loading process, and tearing fracture of the base metal at top and bottom flange of beam occurred. The hysteresis curves of the specimens are both spindle-shaped and plump. The ultimate loads of the single beam-column joint and double beam-column joint are 48.65 kN and 70.60 kN respectively, and the equivalent viscous damping coefficients are more than 0.2 when destroyed, which shows the two specimens have great energy dissipation capacity. In addition, the stiffness, bearing capacity and energy dissipation capacity of the double beam-column joint are significantly better than that of the single beam-column joint. The ductility coefficients of the single beam-column joint and double beam-column joint are 1.81 and 1.92, respectively. The cracks grow fast when subjected to dynamic loading, and the strength and stiffness degradation is also degenerated quickly.

• Steel and Composite Structures
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• v.28 no.2
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• pp.223-231
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• 2018

Nowadays, there are a great number of various structures that have been retrofitted by using different FRP Composites. Due to this, more researches need to be conducted to know more the characteristics of these structures, not only that but also a comparison among them before and after the retrofitting is needed. In this research, a model steel structure is tested using a bench-scale earthquake simulator on the shake table, using recorded micro tremor data, in order to get the dynamic behaviors. Columns of the model steel structure are then retrofitted by using GFRP composite, and then tested on the Quanser shake table by using the recorded micro tremor data. At this stage, it is needed to evaluate the dynamic behaviors of the retrofitted model steel structure. Various types of methods of OMA, such as EFDD, SSI, etc. are used to take action in the ambient responses. Having a purpose to learn more about the effects of GFRP composite, experimental model analysis of both types (retrofitted and no-retrofitted models) is conducted to evaluate their dynamic behaviors. There is a provision of ambient excitation to the shake table by using recorded micro tremor ambient vibration data on ground level. Furthermore, the Enhanced Frequency Domain Decomposition is used through output-only modal identification. At the end of this study, moderate correlation is obtained between mode shapes, periods and damping ratios. The aim of this research is to show and determine the effects of GFRP Composite implementation on structural responses of the model steel structure, in terms of changing its dynamical behaviors. The frequencies for model steel structure and the retrofitted model steel structure are shown to be 33.916% in average difference. Finally, it is shown that, in order to evaluate the period and rigidity of retrofitted structures, OMA might be used.

• Journal of the Society of Naval Architects of Korea
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• v.28 no.2
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• pp.251-267
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• 1991

Plastic strength analysis using plastic failure mode as a limit state is adopted instead of a conventional elastic structural analysis to predict the ultimate strength of Web frame idealized by a plane frame. Linear programming arid Compact procedure are developed for determining the collapse load factor. It is found that the final results are good agreement with the results of Elasto-plastic analysis. Besides, the redundant structures like Web frame is known to have multiple failure modes. Web frame may collapse under any of the possible failure modes. Thus, the identification of these possible failure modes is necessary and very important in the reliability analysis of Web frame. In order to deal with multiple failure modes, automatic generation method of all failure modes and basic failure modes is used for selecting the dominant failure modes. The probability of failure pastic collapse of Web frame is calculated using these dominant failure modes. The safety of Web frame is asscssed and compared by performing the deterministic and probabilistic analysis.

• Journal of Plant Biology
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• v.36 no.2
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• pp.127-132
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• 1993

Self-incompatibility in Brassica campestris is controlled by multi-allele system in a single genetic locus, the S locus, and it is elucidated that S-glycoproteins are S gene products. In this experiments, we examined the genetic mode(pollen tube behavior and segregation of S-glycoprotein), characteristic of S-glycoproteins and DNA constitution within nuclear genome on S gene family that unexplained by single locus model, and investigated the segregation pattern of S-glycoproteins in bred F1 generation. By diallel cross among the 15 plants within one family the existence of three types of homozygotes and three types of heterozygotes were observed, and segregation of S-allele could not explained by single locus model. From the results of IEF-immunoblot analysis for non-segregated individual plant, the segregation pattern of S specific bands was corresponded with results of diallel cross except with one case(SaSa genotype). The molecular weight of 6 different S-genotype varied in near by 50 kD, and each genotype expressed with 2 or 3 bands. Specific bands in SaSa, SbSb, ScSc has almost similar molecular weight between them. Southern analysis of genomic DNA probed with S-glycoprotein cDNA for 6 different genotypes revealed that there are clear difference in polymorphism, multiple bands of hybridization, when restriction enzymes of EcoR I were used. It could be assumed that there are several sequences related to the S-glycoprotein structural genes within their nuclear genome. Therefore, we suggested the possibilities that S-allele system could be controlled by multi-locus, that dominance-recessive interactions could be explained by modifier gene or supressor gene based on the results of abnormal segregation of S-glycoprotein in bred F1. The F2 analyses are progressing in now.

• Journal of IKEEE
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• v.21 no.3
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• pp.252-255
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• 2017

$Mo_xW_{1-x}Si_2$ heaters were fabricated by self-propagating high-temperature synthesis (SHS) process and post sintering process. To validate the reliability of the $Mo_xW_{1-x}Si_2$ heaters, the accelerated life test (ALT) was conducted, and then lifetime to $Mo_xW_{1-x}Si_2$ heaters was estimated by using Minitab programs. Also, the failure analysis of $Mo_xW_{1-x}Si_2$ heaters after ALT was performed through electrical and structural properties. As the results, it was confirmed that the dominant failure mode of $Mo_xW_{1-x}Si_2$ heaters is the crack formation in heaters and the delamination of protective $SiO_2$ layers.

• Earthquakes and Structures
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• v.8 no.3
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• pp.555-572
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• 2015

This paper presents an experimental study of three two-dimensional (2D/planar) steel reinforced concrete (SRC) T-shaped column-RC beam hybrid joints and six 3D SRC T-shaped column-steel beam hybrid joints under low cyclic reversed loads. Considering different categories of steel configuration types in column cross section and horizontal loading angles for the specimens were selected, and a reliable structural testing system for the spatial loading was employed in the tests. The load-displacement curves, carrying capacity, energy dissipation capacity, ductility and deformation characteristics of the test subassemblies were analyzed. Especially, the seismic performance discrepancies between planar hybrid joints and 3D hybrid joints were intensively compared. The failure modes for planar loading and spatial loading observed in the tests showed that the shear-diagonal compressive failure was the dominating failure mode for all the specimens. In addition, the 3D hybrid joints illustrated plumper hysteretic loops for the columns configured with solid-web steel, but a little more pinched hysteretic loops for the columns configured with T-shaped steel or channel-shaped steel, better energy dissipation capacity & ductility, and larger interlayer deformation capacity than those of the planar hybrid joints. Furthermore, it was revealed that the hysteretic loops for the specimens under $45^{\circ}$ loading angle are generally plumper than those for the specimens under $30^{\circ}$ loading angle. Finally, the effects of steel configuration type and loading angle on the seismic damage for the specimens were analyzed by means of the Park-Ang model.

• Structural Engineering and Mechanics
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• v.31 no.4
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• pp.453-475
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• 2009

The literature regarding the free vibration analysis of Bernoulli-Euler and Timoshenko beams on elastic soil is plenty, but the free vibration analysis of Reddy-Bickford beams on elastic soil with/without axial force effect using the Differential Transform Method (DTM) has not been investigated by any of the studies in open literature so far. In this study, the free vibration analysis of axially loaded Reddy-Bickford beam on elastic soil is carried out by using DTM. The model has six degrees of freedom at the two ends, one transverse displacement and two rotations, and the end forces are a shear force and two end moments in this study. The governing differential equations of motion of the rectangular beam in free vibration are derived using Hamilton's principle and considering rotatory inertia. Parameters for the relative stiffness, stiffness ratio and nondimensionalized multiplication factor for the axial compressive force are incorporated into the equations of motion in order to investigate their effects on the natural frequencies. At first, the terms are found directly from the analytical solutions of the differential equations that describe the deformations of the cross-section according to the high-order theory. After the analytical solution, an efficient and easy mathematical technique called DTM is used to solve the governing differential equations of the motion. The calculated natural frequencies of one end fixed and the other end simply supported Reddy-Bickford beam on elastic soil using DTM are tabulated in several tables and figures and are compared with the results of the analytical solution where a very good agreement is observed and the mode shapes are presented in graphs.

• Molecules and Cells
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• v.41 no.6
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• pp.545-552
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• 2018

Spleen tyrosine kinase (SYK) is a cytosolic non-receptor protein tyrosine kinase. Because SYK mediates key receptor signaling pathways involving the B cell receptor and Fc receptors, SYK is an attractive target for autoimmune disease and cancer treatments. To date, representative oral SYK inhibitors, including fostamatinib (R406 or R788), entospletinib (GS-9973), cerdulatinib (PRT062070), and TAK-659, have been assessed in clinical trials. Here, we report the crystal structures of SYK in complex with two newly developed inhibitors possessing 4-aminopyrido[4,3-D]pyrimidine moieties (SKI-G-618 and SKI-O-85). One SYK inhibitor (SKI-G-618) exhibited moderate inhibitory activity against SYK, whereas the other inhibitor (SKI-O-85) exhibited a low inhibitory profile against SYK. Binding mode analysis indicates that a highly potent SYK inhibitor might be developed by modifying and optimizing the functional groups that interact with Leu377, Gly378, and Val385 in the G-loop and the nearby region in SYK. In agreement with our structural analysis, one of our SYK inhibitor (SKI-G-618) shows strong inhibitory activities on the ${\beta}$-hexosaminidase release and phosphorylation of SYK/Vav in RBL-2H3 cells. Taken together, our findings have important implications for the design of high affinity SYK inhibitors.

• Journal of the Korea Concrete Institute
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• v.20 no.2
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• pp.257-267
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• 2008

Results of seventy-seven specimens tested by this study and previous research were collected and evaluated to propose the flexural strength and shear strength for flexural members with steel fiber concrete. For strength evaluation, structural parameters such as compressive strength, steel fiber content, tensile reinforcement ratio, and shear span to effective depth ratio are involved. The proposed equations for flexural and shear strength are regarded to give a good prediction for the strength of steel fiber reinforced composite and/or RC beams to compare with equations by previous researchers. Especially, the proposed shear strength equation in this study shows the lowest the mean value, the coefficient of variation and the error ratio among predictions by several equations. Therefore, equations for shear strength and flexure strength, which are proposed in this study are to be useful measure to predict the actual behavior and failure mode of steel fiber reinforced composite beams.