• Applied Biological Chemistry
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• 제37권5호
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• pp.339-342
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• 1994

Streptomyces rochei 87051-3의 발효액에서 제초성 물질을 분리하고 maculosin-1, -5 및 -6으로 동정하였다. 이것은 Streptomyces에서 이들 물질이 분리된 최초의 보고이다.

• Applied Biological Chemistry
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• 제36권6호
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• pp.476-480
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• 1993

제초성항생물질인 maculosin과 phenylacetic acid를 생산하는 균주를 Streptomyces rochei로 동정하였다. 동정은 형태학적 및 생리학적 특성시험에 기초하였다. 이 균주는 진균류인 Alternaria altenata 외에 maculosin의 생성이 보고된 최초의 Streptomyces 속 균주이다.

• Journal of Microbiology and Biotechnology
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• 제6권4호
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• pp.260-264
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• 1996

An isolate, 90-GT-129 was found to produce antibiotics with a selective inhibitory activity against Streptococcus pyogenes and Xanthomonas sp. The isolate formed a gray spiral aerial spore mass with smooth surface. Analysis of the cell wall acid hydrolysate of the isolate revealed presence of LL-di-aminopimelic acid, which indicates that the isolate belongs to a cell wall type Ⅰ actinomycetes. Cultural and physiological characteristics of the isolate placed it in Streptomyces rochei synonym cluster. A comparison of the isolate with 26 reference strains of Streptomyces rochei synonym demonstrated differences in physiological and cultural characteristics.

• Journal of Microbiology and Biotechnology
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• 제6권4호
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• pp.265-269
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• 1996

An isolate of Streptomyces rochei synonym was found to produce antibiotics with narrow anti-microbial spectrum against Streptococcus and Xanthomonas sp. Among the antibiotic complex produced by the strain, the main active compound was isolated, and its physico-chemical properties and biological activities were investigated. Molecular weight of the compound was determined to be ${[M+H]}^+$ 797 (FAB-MS). UV, $^1H \;and\;^{13}C$ NMR, and IR spectra suggested that the compound is a kirromycin-like aurodox group antibiotic. However, the anti-microbial spectrum of the main compound was slightly different from that of kirromycin. In addition, it was newly found that kirromycin showed a selective anti-microbial activity against Streptococcus pyogenes and phytopathogenic Xanthomonas sp.

• Journal of Microbiology
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• 제33권4호
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• pp.315-321
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• 1995

The relationship between morphological differentiation and production of trypsin-like protease (TLP_ in streptomycetes was studied. All the Streptomyces spp.In this study produced TLP just before the onset of aerial mycelium formation. Addition of TLP inhibitor, TLCK, to the top surface of colonies inhibited aerial mycelium formation as well as TLP inhibitor, TLCK, to the top surface of colonies inhibited aerial mycelium formation as well as TLP activity. Addition of 2% glucose to the Bennett agar medium repressed both the aerial mycelium formation and TLP production in S. abuvaviensis, S. coelicolor A3(2), S exfoliatus, S. microflavus, S. roseus, s. lavendulae, and S. rochei. However the addition of glucose did not affect S. limosus, S. felleus, S. griseus, S. phaechromogenes, and S. rimosus. The glucose repression on aerial mycelium formation and production of TLP was relieved by the addition of glucose anti-metabolite (methyl .alpha.-glucopyranoside). Therefore, it was concluded that TLP production is coordinately regulated with morphological differentiation and TLP activity is essential for morphological differentiation in streptomycetes. The proposed role of TLP is that TLP participates in the degradation of substrate mycelium protein for providing nutrient for aerial mycelial growth.