• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.4
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• pp.1216-1231
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• 2021

With the increase in the population of our cities and the rapid increase in the number of private cars, urban traffic has become more and more congested. At this stage, urban public transportation has become one of the main ways to improve urban traffic congestion. Aiming at the problem of how to improve the basic capacity of buses in multi-line transfer stations, this paper conducts simulation research based on anylogic software. Through micro-simulation analysis of vehicles entering, stopping, and exiting the station, combined with the delay model theory, the vehicle is given Stop organization optimization and station layout improvement methods, so that vehicles can run in the station more stably, smoothly and safely. Case analysis shows that applying this method to the roadside parking problem, the main and auxiliary bus stations have a significant improvement in operating capacity compared with the conventional tandem double bus stations, and the service level of the main and auxiliary bus stations has been significantly improved.

• Journal of the Korean Society of Safety
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• v.37 no.4
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• pp.28-35
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• 2022

This study is aimed to develop a safety diagnosis system for fire pumps that detects normal and abnormal signals for the stable operation of the system. Hence, the following activities were carried out: first, a threshold value was identified for the normal operation and six abnormal operations (adherence of impeller, absence of water source, separation of pump and motor, run-stop operation, air inflow into the casing, and reverse-phase loss of the power line) reflecting changes in the current, flow and pressure of fire pumps; secondly, based on the identified signals, an algorithm capable of detecting three abnormal signals was developed and in terms of hardware, a current, pressure and flow sensor suitable for the analogue input values of NI-6009 was designed and installed. This combination of the hardware and software is applicable as a diagnosis system to ensure the stable operation of fire pumps.

• Tuberculosis and Respiratory Diseases
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• v.67 no.4
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• pp.325-330
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• 2009

Background: Pulmonary tuberculosis (TB) is still common disease among the elderly patients in Korea where the overall incidence of TB is decreasing. Adverse drug reactions (ADR) associated with anti-TB drugs occurs frequently. Especially the aged tends to have more frequent ADRs than younger ones. These ADRs can cause significant morbidity, compromise therapeutic effects of drugs and even induce drug resistance. Therefore we evaluated the effect of ADRs on the first-line anti-TB drugs in elderly patients with active pulmonary TB. Methods: We retrospectively reviewed the charts and radiological findings of the patients with 65 and older who were bacteriologically confirmed as active TB and treated with standard anti-TB drugs for at least 6 months. Major ADR was defined with temporary or continuous stop of any first-line drugs intake. Results: An ADR was noted in 54% of all patients. The incidence of major ADR was 32% in all elderly patients. Dermatologic ADR (9%) was the most common among the major ADRs. GI trouble (8%), arthralgia (6%), visual change (6%), hepatotoxicity (4%), and fever (1%) were also noted. The drugs responsible for major ADR were ethambutol (62%), pyrazinamide (35%), rifampin (18%) and isoniazid (9%). Major ADRs were associated with higher ESR level at the initiation of anti-TB drugs. Conclusion: First-line anti-TB drugs in elderly patients frequently caused the major ADRs. Therefore the elderly patients receiving anti-TB drugs should be closely monitored and better tolerable therapy should be considered as part of a TB research agenda.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.10
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• pp.3911-3916
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• 2010

In this paper we describe contents and results on running test for ATP on-board equipment, which has propelled as one of the research projects, so called, "Reliability assessment and operation technology development for Korean-type tilting trains" in order to ensure the safety and operation efficiency of tilting trains. We developed tilting trains for the speed-up of conventional lines and for the passenger service improvement where the KTX is not available. And we made progress the operation trial test in the 120,000 km distance with the use of ATS equipment, used in existing lines, for the purpose of the reliability assessment of the developed tilting trains. We decided to accelerate the speed for more than 200km/h with respect to the 6 existing lines including Jungang-line and Chungbuk-line where KTX has not operated. According to this decision, Train control system is to be changed from ATS to ATP. We should have installed an ATP on-board unit in tilting trains and verified the operational suitability, therefore we installed the same ATP on-board unit on tilting trains as that used in the ATP construction project on Gyeongbu-line and Honam-line, and verified that the function and performance of the installed ATP on-board unit conformed to the tilting trains operation.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.2
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• pp.7-13
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• 2011

This paper presents a Time-to-Digital Converter which is a key block of an All-Digital Phase Locked Loop. In this work, a Vernier Delay Line is added in a conventional Gated Ring Oscillator, so it could get multi-phases and a high resolution. The Gated Ring Oscillator uses 7 unit delay cell, the Vernier Delay Line is used each delay cell. So proposed Time-to-Digital Converter uses total 21 phases. This Time-to-Digital Converter circuit is designed and laid out in $0.13{\mu}m$ 1P-6M CMOS technology. The proposed Time-to-Digital Converter achieves 26ps resolution, maximum input signal frequency is 100MHz and the digital output of proposed Time-to-Digital Converter are 8-bits. The proposed TDC detect 5ns phase difference between Start and Stop signal. A power consumption is 8.4~12.7mW depending on Enable signal width.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.8
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• pp.887-894
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• 2007

In this paper, design and fabrication of the LPF with controllable four transmission zeros using electric coupling and added open stub is presented. Pass-band of the LPF is GSM band, and two transmission zeros are generated by the electric coupling at the WiBro and S-DMB band, And the other two transmission zeros are generated by the open stub at the upper frequencies. Harmonic frequency of the stop-band is suppressed by the realization of the filter using quasi-lumped element with small parasitic values. $C_M$, which is the electric coupling element of the equivalent circuit, is realized by the distance control between the open stubs of the filter structure. The fabricated LPF used teflon substrate with relative permittivity of 2.6. And it has a size of $38{\times}20{\times}0.79 mm^3$, which is including a feed line. The measured 3 dB cut-off frequency is 1.55 GHz, and locations of the transmission zeros are 2.20, 2.43, 4.11 and 6.84 GHz, respectively.

• Journal of Korean Society of Transportation
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• v.35 no.1
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• pp.79-89
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• 2017

The purpose of this study is to analyze the current right-turn operation at signalized intersections and suggest appropriate right-turn operation strategy. From field investigation, right-turn signals have not only operated various type and shape, lacking of consistency, but also there was no clear regulations or standards. It could increase drivers' confusion and cause vehicle-to-pedestrian accidents. In order to improve pedestrian safety, there is urgent need to study the regulations and standards regarding to right-turn traffic control. This study suggests appropriate right-turn signal operation strategy. In case of permissive right-turn operation, it should be stated on regulations that red light means right-turn vehicles must stop temporarily at the stop line and then turn right. Necessary conditions for installing right-turn signal for protected operation are that there should have one or more exclusive right-turn lanes and right-turn signal face should contain the lenses with three-color arrow indication. In addition, we assort right-turn operation types as permissive, protected and protected/permissive right-turn and suggest specific signal operation strategy by the types.

• Journal of agricultural medicine and community health
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• v.31 no.3
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• pp.237-244
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• 2006

Objectives: DASH (dietary approaches to stop hypertension) diet are recommended as first-line therapy for prevention of hypertension individuals with high normal blood pressure. We studied the effects of DASH program on blood pressure among the pre-hypertension group. Methods: To determine the impact of dietary patterns on the control of hypertension we studied the subgroup of 141 participants with systolic blood pressure of 120 to 139 mm Hg or diastolic BP of 80 to 89mmHg, body mass index(BMI) ${\geq}25kg/m^3$ or waist to hip ratio(WHR) ${\geq}0.95$(for man). 0.85(for woman) enrolled in DASH program. Participants were received of education and consulting about DASH every week for 8 weeks. Results: The level of diet to prevention of hypertension and compliance of DASH increased after education. Also, The DASH program significantly reduced systolic BP (from $136.03{\pm}12.40mmHg$ to $126.09{\pm}11.25mmHg$, p< .01) and diastolic BP (from $81.80{\pm}6.32mmHg$ to $76.44{\pm}10.61mmHg$, p< .01). Conclusion: The DASH program effectively lowers BP and may be useful in achieving prevention of hypertension.

• The KIPS Transactions:PartD
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• v.15D no.1
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• pp.121-130
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• 2008

In line with the enhanced weight and variety of electronic commerce in business activities, new type of payment settlement and banking system which will enable to store, create and transfer values from the existing method of payment settlement is highly required. Cyber Banking system draws strong attention being the solution of there requirements. The existing Cyber Banking system has the difficulty of operation, administration, in addition to the problem of initial facility investment of big amount, resulted from the usage of the current business process. As the existing Cyber Bank system is unable to carry out the function of storing, creating, and transferring values due to the adoption conventional credit card system instead of the application of non-stop payment system between the seller and buyer. As a result, current Cyber Bank system still imply the deficiency of non-performing cash payment function on internet. This paper describes (1) an integrated application process, One Process One Input (OPOI) which is essential for software development of the Cyber Bank, (2) an application process of payment settlement system to be applied to the electronic commerce in Internet. And then, with these for a basis, (3) design and implementation of payment settlement system through CyberBank for Electronic Commerce. Consequently, by means of this suggested process, we could attempt to solve the problem of existing Cyber Bank system and further to explore the possibility of advanced Cyber Banking being the non-stop payment settlement system. The effectiveness of this suggested system has been practically confirmed.

• Journal of Acupuncture Research
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• v.20 no.2
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• pp.98-111
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• 2003

Objective : This study was designed to analyze the effects of bee venom and melittin on cell death in neuroblastoma cell line. Methods : MTT assay, morphologic method, DNA fragmentation, flow cytometry, immunocytochemistry analysis, RT-PCR and Western blot were performed. Results : The obtained results are summarized as follows: 1. The MTT assay demonstrated that neuroblastoma cell viability was significantly inhibitted dose-dependently by treatment with bee venom and melittin in comparison with control. 2. Cell culture demonstrated that control group proliferated highestly at he 5th day in comparison with the 4th day in bee venom and melittin group. And in bee venom and melitti group cell proliferation decreased 2.5 times than control group. 3. The morphologic study demonstrated that neuroblastoma cell showed apoptosis after treatment with bee venom and melittin for 6 hours using microscope. 4. The Flow cytometry demonstrated that apoptosis of neuroblastoma cell treated with bee venom and melittin was related with stop of cell cycle in stage of $G_0/G_1$. 5 .DNA fragmenation demonstrated that neuroblastoma cell treated with bee venom and melittin showed DNA ladder below 1 Kbp. 6. Immunocytochemistry assay demonstrated that Fos and MAPK which are related with cancer were down-regulated by treatment with bee venom and melittin. 7. RT-PCR analysis demonstrated that Fos and MAPK mRNA were transcripted. Fos was down-regulated form treatment with $5{\mu}g/ml$ bee venom and MAPK was down-regulated form $1{\mu}g/ml$ bee venom. 8. Western blot demonstrated that Fos was down-regulated from $1{\mu}g/ml$ bee venom whereas MAPK was expressed by $1{\mu}g/ml$ bee venom but down-regulated by $10{\mu}g/ml$ bee venom. Conclusions : We found that some cancer related genes ware down-regulated by treatment with bee venom and melittin. Further study is needed for investigating the anti-cancer effect of bee venom and melittin.